Fabian Schumacher

Fabian Schumacher

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Fabian Schumacher

Fabian Schumacher

Publications by authors named "Fabian Schumacher"

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51Publications

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Acid Sphingomyelinase Deficiency Ameliorates Farber Disease.

Int J Mol Sci 2019 Dec 11;20(24). Epub 2019 Dec 11.

Department of Molecular Biology, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.

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http://dx.doi.org/10.3390/ijms20246253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941101PMC
December 2019

Monitoring the Sphingolipid Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry.

Front Cell Dev Biol 2019 1;7:210. Epub 2019 Oct 1.

Department of Toxicology, University of Potsdam, Nuthetal, Germany.

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http://dx.doi.org/10.3389/fcell.2019.00210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779703PMC
October 2019

Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis.

Front Cell Dev Biol 2019 15;7:226. Epub 2019 Oct 15.

Institute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.3389/fcell.2019.00226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803391PMC
October 2019

Acid sphingomyelinase - a regulator of canonical transient receptor potential channel 6 (TRPC6) activity.

J Neurochem 2019 Sep 22;150(6):678-690. Epub 2019 Aug 22.

Department of Chemistry and Pharmacy, Molecular and Clinical Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1111/jnc.14823DOI Listing
September 2019

Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells.

Epigenetics 2019 Sep 17:1-16. Epub 2019 Sep 17.

Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam , Nuthetal , Germany.

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http://dx.doi.org/10.1080/15592294.2019.1666652DOI Listing
September 2019

Nationwide central diagnosis review for childhood solid tumors: From concept to realization of an Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) integrated project.

Pediatr Blood Cancer 2019 08 17;66(8):e27749. Epub 2019 Apr 17.

Pediatric Onco-Haematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, Azienda Ospedaliera-Universitaria Città della Salute e della Scienza, Torino, Italy.

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http://dx.doi.org/10.1002/pbc.27749DOI Listing
August 2019

Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia.

J Mol Med (Berl) 2019 Aug 20;97(8):1195-1211. Epub 2019 Jun 20.

Department of Surgery, College of Medicine, University of Cincinnati, 231 Albert Sabin Way ML 0558, Cincinnati, OH, 45267, USA.

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http://dx.doi.org/10.1007/s00109-019-01800-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647234PMC
August 2019

Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels.

Pharmaceutics 2019 Aug 5;11(8). Epub 2019 Aug 5.

Clinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.

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http://dx.doi.org/10.3390/pharmaceutics11080394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723892PMC
August 2019

1-Methoxy-3-indolylmethyl DNA adducts in six tissues, and blood protein adducts, in mice under pak choi diet: time course and persistence.

Arch Toxicol 2019 Jun 15;93(6):1515-1527. Epub 2019 Apr 15.

Department of Nutritional Toxicology, Institute of Human Nutrition Potsdam-Rehbrücke, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.

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http://link.springer.com/10.1007/s00204-019-02452-3
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http://dx.doi.org/10.1007/s00204-019-02452-3DOI Listing
June 2019

Identification of functional lipid metabolism biomarkers of brown adipose tissue aging.

Mol Metab 2019 06 4;24:1-17. Epub 2019 Apr 4.

Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; German Center for Diabetes Research (DZD), München, Neuherberg, Germany; Institute of Nutritional Science, University of Potsdam, Potsdam-Rehbrücke, Nuthetal, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778183119
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http://dx.doi.org/10.1016/j.molmet.2019.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531832PMC
June 2019

Qualifying X-ray and Stimulated Raman Spectromicroscopy for Mapping Cutaneous Drug Penetration.

Anal Chem 2019 Jun 15;91(11):7208-7214. Epub 2019 May 15.

Institute of Pharmacy (Pharmacology and Toxicology) , Freie Universität Berlin , Königin-Luise-Strasse 2 + 4 , 14195 Berlin , Germany.

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http://dx.doi.org/10.1021/acs.analchem.9b00519DOI Listing
June 2019

Core-multishell nanocarriers enhance drug penetration and reach keratinocytes and antigen-presenting cells in intact human skin.

J Control Release 2019 Apr 21;299:138-148. Epub 2019 Feb 21.

Clinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité-Universitaetsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2019.02.028DOI Listing
April 2019

Interleukin-22 protects intestinal stem cells against genotoxic stress.

Nature 2019 02 30;566(7743):249-253. Epub 2019 Jan 30.

Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://www.nature.com/articles/s41586-019-0899-7
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http://dx.doi.org/10.1038/s41586-019-0899-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420091PMC
February 2019

Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery.

Nanoscale 2018 Sep;10(35):16848-16856

Institut für Chemie und Biochemie, Freie Universität Berlin, Takustr. 3, 14195, Berlin, Germany.

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http://dx.doi.org/10.1039/c8nr05536jDOI Listing
September 2018

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice.

Crit Care 2018 Oct 29;22(1):282. Epub 2018 Oct 29.

Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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https://ccforum.biomedcentral.com/articles/10.1186/s13054-01
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http://dx.doi.org/10.1186/s13054-018-2213-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206919PMC
October 2018

Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery.

Nanoscale 2018 Sep;10(35):16848-16856

Institut für Chemie und Biochemie, Freie Universität Berlin, Takustr. 3, 14195, Berlin, Germany.

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http://dx.doi.org/10.1039/c8nr05536jDOI Listing
September 2018

How Effective Is Tacrolimus in the Imiquimod-Induced Mouse Model of Psoriasis?

J Invest Dermatol 2018 02 22;138(2):455-458. Epub 2017 Sep 22.

Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.09.019DOI Listing
February 2018

Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice.

J Nutr Biochem 2017 10 9;48:112-119. Epub 2017 Jul 9.

Institute of Nutrition, Department of Molecular Nutrition Physiology, Friedrich Schiller University Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2017.07.002DOI Listing
October 2017

Lysophosphatidic Acid Inhibits Insulin Signaling in Primary Rat Hepatocytes via the LPA3 Receptor Subtype and is Increased in Obesity.

Cell Physiol Biochem 2017 1;43(2):445-456. Epub 2017 Sep 1.

Faculty of Mathematics and Natural Science, Institute of Nutritional Science, Department of Toxicology, University of Potsdam, Potsdam, Germany.

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http://dx.doi.org/10.1159/000480470DOI Listing
October 2017

The sphingosine 1-phosphate breakdown product, (2)-hexadecenal, forms protein adducts and glutathione conjugates in vitro.

J Lipid Res 2017 08 6;58(8):1648-1660. Epub 2017 Jun 6.

Department of Nutritional Toxicology, Institute of Nutritional Science, University of Potsdam, 14558 Nuthetal, Germany

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http://dx.doi.org/10.1194/jlr.M076562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538286PMC
August 2017

Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium.

Eur J Pharm Biopharm 2017 Jun 9;115:122-130. Epub 2017 Feb 9.

College of Pharmacy, Freie Universität Berlin, Kelchstr. 31, 12169 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2017.02.001DOI Listing
June 2017

In Silico Prediction of Human Sulfotransferase 1E1 Activity Guided by Pharmacophores from Molecular Dynamics Simulations.

J Biol Chem 2016 Jan 5;291(1):58-71. Epub 2015 Nov 5.

From the Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2/4, 14195 Berlin,

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http://dx.doi.org/10.1074/jbc.M115.685610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697188PMC
January 2016

Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans.

Talanta 2015 Nov 28;144:71-9. Epub 2015 May 28.

Department of Food Chemistry, Institute of Nutritional Science, University of Potsdam, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2015.05.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600537PMC
November 2015

Glucosinolates Are Mainly Absorbed Intact in Germfree and Human Microbiota-Associated Mice.

J Agric Food Chem 2015 Sep 22;63(38):8418-28. Epub 2015 Sep 22.

Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke , Nuthetal, Germany.

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http://pubs.acs.org/doi/10.1021/acs.jafc.5b02948
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http://dx.doi.org/10.1021/acs.jafc.5b02948DOI Listing
September 2015

Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans.

Metallomics 2015 May 13;7(5):847-56. Epub 2015 Mar 13.

Neuroscience Graduate Program, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1039/c5mt00052aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431931PMC
May 2015

Simultaneous detection of multiple DNA adducts in human lung samples by isotope-dilution UPLC-MS/MS.

Anal Chem 2015 Jan 8;87(1):641-8. Epub 2014 Dec 8.

Research Group Genotoxic Food Contaminants, German Institute of Human Nutrition (DIfE) , 14558 Nuthetal, Germany.

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http://dx.doi.org/10.1021/ac503803mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287830PMC
January 2015

Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry.

Anal Chem 2014 Sep 3;86(18):9065-73. Epub 2014 Sep 3.

Department of Nutritional Toxicology, Institute of Nutritional Science, University of Potsdam , Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.

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http://dx.doi.org/10.1021/ac501677yDOI Listing
September 2014

Optimized enzymatic hydrolysis of DNA for LC-MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol.

Anal Biochem 2013 Mar 9;434(1):4-11. Epub 2012 Nov 9.

German Institute of Human Nutrition, Potsdam-Rehbrücke, 14558 Nuthetal, Germany.

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http://dx.doi.org/10.1016/j.ab.2012.11.001DOI Listing
March 2013

Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.

Anal Chem 2012 Jul 3;84(14):6256-62. Epub 2012 Jul 3.

German Institute of Human Nutrition, Potsdam-Rehbrücke, 14558 Nuthetal, Germany.

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http://dx.doi.org/10.1021/ac301436qDOI Listing
July 2012

How to optimise the coverage rate of infant and adult immunisations in Europe.

BMC Med 2007 May 29;5:11. Epub 2007 May 29.

Infectious Diseases Service at the Zentrum für Präventive Pädiatrie, Johannes Gutenberg Universität, Mainz, Germany.

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http://dx.doi.org/10.1186/1741-7015-5-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1903356PMC
May 2007