Frank Nestle

Frank Nestle

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Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells.

Front Immunol 2018 23;9:493. Epub 2018 Mar 23.

St. John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, Guy's Hospital, London, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2018.00493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876289PMC
April 2019

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment.

Cell 2019 Feb 31;176(4):757-774.e23. Epub 2019 Jan 31.

Barts Cancer Institute, John Vane Science Building, Charterhouse Square, Queen Mary University of London, London EC1M 6BQ, UK; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.12.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370915PMC
February 2019

Unraveling Vascular Inflammation: From Immunology to Imaging.

J Am Coll Cardiol 2017 Sep;70(11):1403-1412

Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.07.750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658004PMC
September 2017

Pathogenesis and immunotherapy in cutaneous psoriasis: what can rheumatologists learn?

Curr Opin Rheumatol 2017 01;29(1):71-78

aSt. John's Institute of Dermatology, King's College London bNIHR Biomedical Research Centre at Guy's and St. Thomas's Hospitals and King's College London, London, UK.

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http://pdfs.journals.lww.com/co-rheumatology/2017/01000/Path
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http://dx.doi.org/10.1097/BOR.0000000000000358DOI Listing
January 2017

Innate and adaptive immune traits are differentially affected by genetic and environmental factors.

Nat Commun 2017 01 5;8:13850. Epub 2017 Jan 5.

Department of Twin Research and Genetic Epidemiology, Kings College London, London SE1 7EH, UK.

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http://dx.doi.org/10.1038/ncomms13850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227062PMC
January 2017

T Cell-Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A-Mediated Epidermal Hyperplasia.

J Immunol 2016 12 24;197(11):4403-4412. Epub 2016 Oct 24.

Division of Rheumatology, Allergy and Clinical Immunology, Department of Internal Medicine, University of California at Davis, Davis, CA 95616;

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http://dx.doi.org/10.4049/jimmunol.1600383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123839PMC
December 2016

Targeting CD8(+) T cells prevents psoriasis development.

J Allergy Clin Immunol 2016 07 9;138(1):274-276.e6. Epub 2016 Jan 9.

Department of Dermatology, University Hospital of Lausanne CHUV, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.10.046DOI Listing
July 2016

IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin.

Sci Rep 2016 07 14;6:29736. Epub 2016 Jul 14.

St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, Faculty of Life Sciences and Medicine, King's College London &NIHR Biomedical Research Centre at Guy's and St. Thomas's Hospitals and King's College London, King's College London, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1038/srep29736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944184PMC
July 2016

Practical guidance on immunogenicity to biologic agents used in the treatment of psoriasis: What can be learnt from other diseases?

J Dermatolog Treat 2015 25;26(6):520-7. Epub 2015 Jun 25.

d Clinic and Policlinic for Dermatology and Allergology, Ludwig-Maximilian-University , Munich , Germany.

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http://dx.doi.org/10.3109/09546634.2015.1034076DOI Listing
May 2016

IgG4 Characteristics and Functions in Cancer Immunity.

Curr Allergy Asthma Rep 2016 Jan;16(1)

St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine; Faculty of Life Sciences and Medicine, King's College London, London, UK.

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http://dx.doi.org/10.1007/s11882-015-0580-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705142PMC
January 2016

Pathogenesis and treatment of psoriasis: exploiting pathophysiological pathways for precision medicine.

Clin Exp Rheumatol 2015 Sep-Oct;33(5 Suppl 93):S2-6. Epub 2015 Oct 15.

St. John's Institute of Dermatology, Guy's and St. Thomas' Hospitals NHS Foundation Trust, London, UK.

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December 2015

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma.

Oncoimmunology 2015 Nov 3;4(11):e1032492. Epub 2015 Jun 3.

St. John's Institute of Dermatology; Division of Genetics and Molecular Medicine; Faculty of Life Sciences and Medicine; King's College London & NIHR Biomedical Research Centre at Guy's and St. Thomas' Hospitals and King's College London; Guy's Hospital; King's College London ; London, UK.

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http://dx.doi.org/10.1080/2162402X.2015.1032492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590000PMC
November 2015

TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination.

Curr Biol 2015 Nov 29;25(22):2899-914. Epub 2015 Oct 29.

Tumour Plasticity Laboratory, Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE11UL, UK. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651903PMC
http://dx.doi.org/10.1016/j.cub.2015.09.054DOI Listing
November 2015

The genetic architecture of the human immune system: a bioresource for autoimmunity and disease pathogenesis.

Cell 2015 Apr 12;161(2):387-403. Epub 2015 Mar 12.

Cutaneous Medicine Unit, St. John's Institute of Dermatology, King's College London, London SE1 9RT, UK; NIHR Biomedical Research Centre at Guy's and St. Thomas' NHS Foundation Trust, London SE1 9RT, UK.

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http://dx.doi.org/10.1016/j.cell.2015.02.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393780PMC
April 2015

Pathway-level disease data mining through hyper-box principles.

Math Biosci 2015 Feb 19;260:25-34. Epub 2014 Sep 19.

Department of Informatics, School of Natural and Mathematical Sciences, King's College London, Strand, London WC2R 2LS, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mbs.2014.09.005DOI Listing
February 2015

Revisiting the role of B cells in skin immune surveillance.

Trends Immunol 2015 Feb 21;36(2):102-11. Epub 2015 Jan 21.

Cutaneous Medicine and Immunotherapy Unit, St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, and National Institute for Health Research (NIHR) Biomedical Research Centre at Guy's and St Thomas' Hospitals and King's College London, London SE1 9RT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.it.2014.12.006DOI Listing
February 2015

Immunogenicity of biotherapy used in psoriasis: the science behind the scenes.

J Invest Dermatol 2015 Jan 14;135(1):31-38. Epub 2014 Aug 14.

St. John's Institute of Dermatology, King's College London School of Medicine, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X153704
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http://dx.doi.org/10.1038/jid.2014.295DOI Listing
January 2015

Effects of BRAF mutations and BRAF inhibition on immune responses to melanoma.

Mol Cancer Ther 2014 Dec 10;13(12):2769-83. Epub 2014 Nov 10.

St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine and NIHR Biomedical Research Centre at Guy's and St. Thomas's Hospitals and King's College London, London, United Kingdom.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258403PMC
December 2014

Psoriasis.

Cold Spring Harb Perspect Med 2014 Aug 1;4(8). Epub 2014 Aug 1.

St. John's Institute of Dermatology, King's College London, London SE1 9RT, United Kingdom National Institute for Health Research GSTT/KCL Comprehensive Biomedical Research Centre, Guy's and St. Thomas' National Health Service Foundation Trust, London SE1 9RT, United Kingdom.

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http://www.dermatology.ca/wp-content/uploads/2012/01/cdnpsor
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http://perspectivesinmedicine.cshlp.org/lookup/doi/10.1101/c
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http://dx.doi.org/10.1101/cshperspect.a015354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109580PMC
August 2014

Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions.

Immunity 2014 Jun 5;40(6):989-1001. Epub 2014 Jun 5.

Division of Molecular Immunology, MRC National Institute for Medical Research, Mill Hill, London NW7 1AA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067745PMC
June 2014

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration.

Nat Commun 2014 Jun 25;5:4255. Epub 2014 Jun 25.

Tumour Plasticity Team, Randall Division of Cell and Molecular Biophysics, King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK.

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http://dx.doi.org/10.1038/ncomms5255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118761PMC
June 2014

The IL-23/IL-17 axis in psoriatic arthritis.

Autoimmun Rev 2014 Apr-May;13(4-5):496-502. Epub 2014 Jan 11.

Department of Internal Medicine, Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, CA 95616, USA; Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children Northern California, CA 95817, USA. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2014.01.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995976PMC
May 2014

Mechanisms regulating skin immunity and inflammation.

Nat Rev Immunol 2014 May 11;14(5):289-301. Epub 2014 Apr 11.

St John's Institute of Dermatology and Guy's and St Thomas' Hospital National Institute for Health Research Biomedical Research Centre, King's College London, SE1 9RT London, UK.

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http://dx.doi.org/10.1038/nri3646DOI Listing
May 2014

TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis.

Eur J Immunol 2013 Dec 20;43(12):3138-46. Epub 2013 Nov 20.

St. John's Institute of Dermatology, King's College London, London, UK.

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http://doi.wiley.com/10.1002/eji.201343801
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http://dx.doi.org/10.1002/eji.201343801DOI Listing
December 2013

What on "irf" is this gene 4? Irf4 transcription-factor-dependent dendritic cells are required for T helper 2 cell responses in murine skin.

Immunity 2013 Oct;39(4):625-7

St. John's Institute of Dermatology, King's College London, London SE1 9RT, UK.

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http://dx.doi.org/10.1016/j.immuni.2013.09.008DOI Listing
October 2013

IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape.

Oncoimmunology 2013 Jul 7;2(7):e24889. Epub 2013 May 7.

Cutaneous Medicine and Immunotherapy Unit; St. John's Institute of Dermatology; Division of Genetics and Molecular Medicine & NIHR Biomedical Research Centre at Guy's and St. Thomas's Hospitals and King's College London; London, UK.

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http://dx.doi.org/10.4161/onci.24889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782134PMC
July 2013

Psoriasis.

Annu Rev Pathol 2012 4;7:385-422. Epub 2011 Nov 4.

St. John's Institute of Dermatology, King's College London, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1146/annurev-pathol-011811-132448DOI Listing
April 2013

IgG4 subclass antibodies impair antitumor immunity in melanoma.

J Clin Invest 2013 Apr;123(4):1457-74

National Institute for Health Research Biomedical Research Centre at Guy's and St. Thomas' Hospitals and King's College London, Cutaneous Medicine and Immunotherapy Unit, St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London School of Medicine, Guy's Hospital, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1172/JCI65579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613918PMC
April 2013

Biomarkers in psoriasis and psoriatic arthritis.

Ann Rheum Dis 2013 Apr;72 Suppl 2:ii104-10

St John's Institute of Dermatology, King's College London, London, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-203037DOI Listing
April 2013

Xenogeneic graft-versus-host-disease in NOD-scid IL-2Rγnull mice display a T-effector memory phenotype.

PLoS One 2012 28;7(8):e44219. Epub 2012 Aug 28.

St. John's Institute of Dermatology, King's College London and NIHR Biomedical Research Centre, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044219PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429415PMC
February 2013

Toward prediction of immune mechanisms and design of immunotherapies in melanoma.

Crit Rev Biomed Eng 2012 ;40(4):279-94

Centre for Bioinformatics, Department of Informatics, School of Natural and Mathematical Sciences, King's College London, United Kingdom.

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January 2013

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.

Hum Mol Genet 2012 Dec 21;21(23):5185-92. Epub 2012 Aug 21.

National Institute for Health Research, Biomedical Research Centre, Guy’s and St Thomas’ NHS Foundation Trust, Toronto, ON, Canada M5T 1R8.

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http://dx.doi.org/10.1093/hmg/dds344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490509PMC
December 2012

Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application.

Cancer Immunol Immunother 2012 Sep 3;61(9):1547-64. Epub 2011 Dec 3.

NIHR Biomedical Research Centre at Guy's and St Thomas's Hospitals and King's College London, London, UK.

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http://dx.doi.org/10.1007/s00262-011-1162-8DOI Listing
September 2012

Transcriptome classification reveals molecular subtypes in psoriasis.

BMC Genomics 2012 Sep 12;13:472. Epub 2012 Sep 12.

Centre for Bioinformatics, Department of Informatics, School of Natural and Mathematical Sciences, King's College London, Strand, London WC2R 2LS, UK.

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http://dx.doi.org/10.1186/1471-2164-13-472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481433PMC
September 2012

Advances in the treatment of melanoma.

Clin Med (Lond) 2012 Apr;12(2):168-71

NIHR Biomedical Research Centre at Guy's and St Thomas's Hospitals and King's College London.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954106PMC
http://dx.doi.org/10.7861/clinmedicine.12-2-168DOI Listing
April 2012

Unraveling the autoimmune translational research process layer by layer.

Nat Med 2012 Jan 6;18(1):35-41. Epub 2012 Jan 6.

Division of Gastroenterology and Hepatology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nm.2632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592149PMC
January 2012

The multitasking organ: recent insights into skin immune function.

Immunity 2011 Dec;35(6):857-69

St. John's Institute of Dermatology, King's College London & National Institute for Health Research Biomedical Research Center, Guy's and St. Thomas's Hospitals, London SE1 9RT, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S107476131100512
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http://dx.doi.org/10.1016/j.immuni.2011.12.003DOI Listing
December 2011

Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies.

PLoS One 2011 Apr 29;6(4):e19330. Epub 2011 Apr 29.

Cutaneous Medicine and Immunotherapy Unit, Division of Genetics and Molecular Medicine, NIHR Biomedical Research Centre at Guy's and St. Thomas's Hospitals and King's College London, King's College London School of Medicine, St. John's Institute of Dermatology, Guy's Hospital, King's College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019330PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084832PMC
April 2011

Harnessing dendritic cells in inflammatory skin diseases.

Semin Immunol 2011 Feb 4;23(1):28-41. Epub 2011 Feb 4.

St. John's Institute of Dermatology, King's College London and NIHR Biomedical Research Centre, Guy's and St. Thomas' Hospitals, 9th floor Tower Wing, Guy's Hospital, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1016/j.smim.2011.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235550PMC
February 2011

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Nat Genet 2010 Nov 17;42(11):985-90. Epub 2010 Oct 17.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1038/ng.694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749730PMC
November 2010

Cutting edge: A critical functional role for IL-23 in psoriasis.

J Immunol 2010 Nov 18;185(10):5688-91. Epub 2010 Oct 18.

St. John's Institute of Dermatology, National Institute for Health Research Biomedical Research Centre, King's College London, London, United Kingdom.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1001538
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http://dx.doi.org/10.4049/jimmunol.1001538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776381PMC
November 2010

Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions.

J Invest Dermatol 2010 Jul 6;130(7):1785-96. Epub 2010 May 6.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1038/jid.2010.103DOI Listing
July 2010

The role of IL-23 in the immunopathogenesis of psoriasis.

F1000 Biol Rep 2010 May 24;2. Epub 2010 May 24.

St John's Institute of Dermatology, King's College London School of Medicine; NIHR Biomedical Research Centre; and FOCIS Centre of Excellence at King's College London London SE1 9RT UK.

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http://www.f1000biology.com/reports/10.3410/B2-40
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http://dx.doi.org/10.3410/B2-40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950033PMC
May 2010

Skin immune sentinels in health and disease.

Nat Rev Immunol 2009 Oct 18;9(10):679-91. Epub 2009 Sep 18.

St. John's Institute of Dermatology, King's College London, UK.

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http://dx.doi.org/10.1038/nri2622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947825PMC
October 2009

Psoriasis.

N Engl J Med 2009 Jul;361(5):496-509

St. John's Institute of Dermatology, Federation of Clinical Immunology Societies Centre of Excellence at King's College London and Guy's and St. Thomas' Foundation Trust, London, United Kingdom.

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http://dx.doi.org/10.1056/NEJMra0804595DOI Listing
July 2009

Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells.

Cancer Immunol Immunother 2009 Jun 22;58(6):915-30. Epub 2008 Oct 22.

Cutaneous Medicine and Immunotherapy Unit, St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London School of Medicine, Guy's Tower, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1007/s00262-008-0607-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017872PMC
June 2009

The IL-23/Th17 axis in the immunopathogenesis of psoriasis.

J Invest Dermatol 2009 Jun 26;129(6):1339-50. Epub 2009 Mar 26.

St John's Institute of Dermatology, King's College London School of Medicine and NIHR Biomedical Research Centre, London, UK.

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http://dx.doi.org/10.1038/jid.2009.59DOI Listing
June 2009

A role for Th17 cells in the immunopathogenesis of atopic dermatitis?

J Invest Dermatol 2008 Nov;128(11):2569-71

St. John's Institute of Dermatology, King's College London School of Medicine and NIHR Biomedical Research Centre, London, United Kingdom.

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http://dx.doi.org/10.1038/jid.2008.283DOI Listing
November 2008

Psoriasis.

Authors:
Frank O Nestle

Curr Dir Autoimmun 2008 ;10:65-75

St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London School of Medicine at Guy's, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1159/000131424DOI Listing
August 2008

The cytokine and chemokine network in psoriasis.

Clin Dermatol 2007 Nov-Dec;25(6):568-73

Department of Pathology and Skin Disease Research Program, Oncology Institute and Cardinal Bernardin Cancer Center, Loyola University Chicago Medical Center, Maywood, IL 60153, USA.

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http://dx.doi.org/10.1016/j.clindermatol.2007.08.011DOI Listing
February 2008

Baseline nail disease in patients with moderate to severe psoriasis and response to treatment with infliximab during 1 year.

J Am Acad Dermatol 2008 Feb 20;58(2):224-31. Epub 2007 Dec 20.

Oregon Health Sciences University, Dermatology and Clinical Research, Portland, Oregon 97210, USA.

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http://dx.doi.org/10.1016/j.jaad.2007.07.042DOI Listing
February 2008

Infliximab treatment improves productivity among patients with moderate-to-severe psoriasis.

Eur J Dermatol 2007 Sep-Oct;17(5):381-6. Epub 2007 Aug 2.

Department of Dermatology, Georg-August University; Von-SieboldStrasse 3, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1684/ejd.2007.0234DOI Listing
January 2008

Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide.

Nature 2007 Oct 16;449(7162):564-9. Epub 2007 Sep 16.

Department of Immunology, M. D. Anderson Cancer Center, University of Texas, Houston, Texas 77030, USA.

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http://www.nature.com/articles/nature06116
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http://dx.doi.org/10.1038/nature06116DOI Listing
October 2007

Immunopathogenesis of psoriasis.

Clin Rev Allergy Immunol 2007 Oct;33(1-2):45-56

Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA.

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http://link.springer.com/10.1007/s12016-007-0039-2
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http://dx.doi.org/10.1007/s12016-007-0039-2DOI Listing
October 2007

Deepening our understanding of immune sentinels in the skin.

J Clin Invest 2007 Sep;117(9):2382-5

St. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London School of Medicine, London, United Kingdom.

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http://dx.doi.org/10.1172/JCI33349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952646PMC
September 2007

Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

Nat Med 2007 Jul 1;13(7):836-42. Epub 2007 Jul 1.

Department of Dermatology, University Hospital of Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1038/nm1605DOI Listing
July 2007

The pathogenic role of tissue-resident immune cells in psoriasis.

Trends Immunol 2007 Feb 2;28(2):51-7. Epub 2007 Jan 2.

Division of Immunology and Allergy, University Hospital of Lausanne (CHUV), CH-1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.it.2006.12.005DOI Listing
February 2007

A new lease on life for dendritic cell vaccines?

Authors:
Frank O Nestle

Nat Biotechnol 2006 Dec;24(12):1483-4

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http://dx.doi.org/10.1038/nbt1206-1483DOI Listing
December 2006

Cutaneous malignant lymphomas: update 2006.

J Dtsch Dermatol Ges 2006 Nov;4(11):914-33

Dept. of Dermatology, University Hospital, Zürich, Switzerland.

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http://dx.doi.org/10.1111/j.1610-0387.2006.06069.xDOI Listing
November 2006

Animal models of psoriasis and psoriatic arthritis: an update.

Curr Rheumatol Rep 2006 Oct;8(5):342-7

Department of Dermatology, University Hospital Zurich, 8091 Zurich, Switzerland.

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October 2006

Defining upstream elements of psoriasis pathogenesis: an emerging role for interferon alpha.

J Invest Dermatol 2005 Nov;125(5):xiv-xv

Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1111/j.0022-202X.2005.23923.xDOI Listing
November 2005

Cancer vaccines: the next generation of tools to monitor the anticancer immune response.

PLoS Med 2005 Oct 25;2(10):e339. Epub 2005 Oct 25.

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.plos.org/10.1371/journal.pmed.0020339
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http://dx.doi.org/10.1371/journal.pmed.0020339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1261511PMC
October 2005

Dendritic-cell-based therapeutic vaccination against cancer.

Curr Opin Immunol 2005 Apr;17(2):163-9

Department of Dermatology, University Hospital of Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.coi.2005.02.003DOI Listing
April 2005

Antigen specific immunotherapy: Quo vadis?

Authors:
Frank O Nestle

Swiss Med Wkly 2005 Apr;135(15-16):211

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http://dx.doi.org/2005/15/smw-10997DOI Listing
April 2005

Metastatic melanoma secreted IL-10 down-regulates CD1 molecules on dendritic cells in metastatic tumor lesions.

Am J Pathol 2004 Dec;165(6):1853-63

Department of Dermatological Sciences, University of Florence Medical School, Florence, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618726PMC
http://dx.doi.org/10.1016/S0002-9440(10)63238-5DOI Listing
December 2004

The IL-12 family member p40 chain as a master switch and novel therapeutic target in psoriasis.

J Invest Dermatol 2004 Dec;123(6):xiv-xv

Department of Dermatology, University Hospital of Zurich, Gloriastrasse, Zurich, Switzerland.

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http://dx.doi.org/10.1111/j.0022-202X.2004.23488.xDOI Listing
December 2004

Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities.

J Clin Invest 2004 Jun;113(12):1664-75

Skin Disease Research Laboratory and Cardinal Bernardin Cancer Center, Loyola University of Chicago, Medical Center, Maywood, Illinois 60153, USA.

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http://dx.doi.org/10.1172/JCI22147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420513PMC
June 2004