Ewa M Urbanska

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Ewa M Urbanska

Publications by authors named "Ewa M Urbanska"

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29Publications

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Prolonged therapy with antidepressants increases hippocampal level of kynurenic acid and expression of Kat1 and Kat2 genes.

Pharmacol Rep 2018 Jan 31;70(4):737-745. Epub 2018 Jan 31.

Department of Clinical Neuroscience, Karolinska Institute, Section of Psychiatry at Karolinska University Hospital Huddinge, Stockholm, Sweden.

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January 2018

Correlations of Kynurenic Acid, 3-Hydroxykynurenine, sIL-2R, IFN-α, and IL-4 with Clinical Symptoms During Acute Relapse of Schizophrenia.

Neurotox Res 2017 Jul 8;32(1):17-26. Epub 2017 Mar 8.

Laboratory of Cellular and Molecular Pharmacology, Department of Experimental and Clinical Pharmacology, Medical University, Lublin, Poland.

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July 2017

[The kynurenic acid hypothesis - a new look at etiopathogenesis and treatment of schizophrenia].

Pol Merkur Lekarski 2016 Sep;41(243):160-164

I Department of Psychiatry, Psychotherapy and Early Intervention, Medical University of Lublin; II Departament of Psychiatry and Psychiatry Rehabilitation, Medical University of Lublin.

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September 2016

Experimental diabetes mellitus type 1 increases hippocampal content of kynurenic acid in rats.

Pharmacol Rep 2014 Dec 10;66(6):1134-9. Epub 2014 Aug 10.

Medical University of Lublin, Lublin, Poland; Institute of Agricultural Medicine, Lublin, Poland. Electronic address:

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December 2014

New insight into the antidepressants action: modulation of kynurenine pathway by increasing the kynurenic acid/3-hydroxykynurenine ratio.

J Neural Transm (Vienna) 2012 Feb 10;119(2):235-43. Epub 2011 Jun 10.

Department of Experimental and Clinical Pharmacology, Medical University, Jaczewskiego 8, 20-090, Lublin, Poland.

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February 2012

Novel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro.

Neurotox Res 2011 Jul 14;20(1):40-50. Epub 2010 Sep 14.

Family Medicine Department, Medical University of Lublin, Staszica 13, 20-081 Lublin, Poland.

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July 2011

beta-adrenergic enhancement of brain kynurenic acid production mediated via cAMP-related protein kinase A signaling.

Prog Neuropsychopharmacol Biol Psychiatry 2009 Apr 12;33(3):519-29. Epub 2009 Feb 12.

Department of Experimental and Clinical Pharmacology, Skubiszewski Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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April 2009

Clenbuterol enhances the production of kynurenic acid in brain cortical slices and glial cultures.

Pharmacol Rep 2008 Jul-Aug;60(4):574-7

Department of Pharmacology and Clinical Pharmacology, Skubiszewski Medical School, Jaczewskiego 8, PL 20-090 Lublin, Poland.

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January 2009

Enhanced glutamatergic transmission reduces the anticonvulsant potential of lamotrigine but not of felbamate against tonic-clonic seizures.

Pharmacol Rep 2007 Jul-Aug;59(4):462-6

Department of Pharmacology and Clinical Pharmacology, Skubiszewski Medical University of Lublin, Jaczewskiego 8, PL 20-090 Lublin, Poland.

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May 2008

Memantine increases brain production of kynurenic acid via protein kinase A-dependent mechanism.

Neurosci Lett 2008 Apr 17;435(2):169-73. Epub 2008 Feb 17.

Department of Experimental and Clinical Pharmacology, Skubiszewski Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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April 2008

Hyperglycemia enhances the inhibitory effect of mitochondrial toxins and D,L-homocysteine on the brain production of kynurenic acid.

Pharmacol Rep 2007 May-Jun;59(3):268-73

Family Medicine Department, Skubiszewski Medical University of Lublin, Staszica 13, PL 20-081 Lublin, Poland.

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January 2008

SNAP and SIN-1 increase brain production of kynurenic acid.

Eur J Pharmacol 2007 Jun 3;563(1-3):130-3. Epub 2007 Mar 3.

Department of Pharmacology, Skubiszewski Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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June 2007

Serum kynurenic acid positively correlates with cardiovascular disease risk factor, homocysteine: a study in stroke patients.

Pharmacol Rep 2006 Jul-Aug;58(4):507-11

Department of Pharmacology and Toxicology, Skubiszewski Medical University in Lublin, Jaczewskiego 8, PL 20-090 Lublin, Poland.

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January 2007

Enhancement of brain kynurenic acid production by anticonvulsants--novel mechanism of antiepileptic activity?

Eur J Pharmacol 2006 Jul;541(3):147-51

Department of Pharmacology, Skubiszewski Medical University, Lublin, Poland.

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July 2006

Effect of pesticides on kynurenic acid production in rat brain slices.

Ann Agric Environ Med 2005 ;12(2):177-9

Department of Toxicology, Institute of Agricultural Medicine, Lublin, Poland.

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April 2006

Homocysteine, a risk factor for atherosclerosis, biphasically changes the endothelial production of kynurenic acid.

Eur J Pharmacol 2005 Jul;517(3):217-23

Department of Cardiosurgery, Skubiszewski Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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July 2005

Adenosine A1 receptors and the anticonvulsant potential of drugs effective in the model of 3-nitropropionic acid-induced seizures in mice.

Eur Neuropsychopharmacol 2005 Jan;15(1):85-93

Department of Pharmacology and Toxicology, Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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January 2005

Carbamazepine enhances brain production of kynurenic acid in vitro.

Eur J Pharmacol 2004 Sep;498(1-3):325-6

Department of Pharmacology and Toxicology, Skubiszewski Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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September 2004

Endogenous level of kynurenic acid and activities of kynurenine aminotransferases following transient global ischemia in the gerbil hippocampus.

Pol J Pharmacol 2003 May-Jun;55(3):443-7

Department of Pharmacology and Toxicology, Medical University, Jaczewskiego 8, PL 20-090 Lublin, Poland.

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February 2004

FK506 attenuates 1-methyl-4-phenylpyridinium- and 3-nitropropionic acid-evoked inhibition of kynurenic acid synthesis in rat cortical slices.

Acta Neurobiol Exp (Wars) 2003 ;63(2):101-8

Department of Pharmacology and Toxicology, Medical University, 8 Jaczewskiego St., 20-090 Lublin, Poland.

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September 2003

1-Methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats.

Neurosci Lett 2002 Sep;330(1):49-52

Department of Pharmacology and Toxicology, Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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September 2002

Endothelium-dependent production and liberation of kynurenic acid by rat aortic rings exposed to L-kynurenine.

Eur J Pharmacol 2002 Jul;448(2-3):133-7

Department of Cardiosurgery, Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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July 2002

Regulation of kynurenic acid synthesis in C6 glioma cells.

J Neurosci Res 2002 Jun;68(5):622-6

Department of Pharmacology and Toxicology, Medical University, Lublin, Poland.

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June 2002

Propranolol and metoprolol enhance the anticonvulsant action of valproate and diazepam against maximal electroshock.

Pharmacol Biochem Behav 2002 Jan-Feb;71(1-2):223-31

Department of Pharmacology and Toxicology, Medical University, Jaczewskiego 8, 20-090 Lublin, Poland.

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April 2002