Ewa Ehrenborg

Ewa Ehrenborg

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Ewa Ehrenborg

Ewa Ehrenborg

Publications by authors named "Ewa Ehrenborg"

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Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.

J Mol Cell Cardiol 2019 Sep 15. Epub 2019 Sep 15.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.09.003DOI Listing
September 2019

Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions.

Mol Ther 2018 04 31;26(4):1040-1055. Epub 2018 Jan 31.

Department of Medicine, Karolinska Institute, Stockholm, Sweden; Department of Vascular and Endovascular Surgery, Technical University Munich, Munich, Germany; German Center for Cardiovascular Research (DZHK), Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080193PMC
April 2018

Lack of genetic susceptibility in takotsubo cardiomyopathy: a case-control study.

BMC Med Genet 2018 03 7;19(1):39. Epub 2018 Mar 7.

Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Sjukhusbacken 10, 11883, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12881-018-0544-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842616PMC
March 2018

Genetic variants of increased waist circumference in psychosis.

Psychiatr Genet 2017 12;27(6):210-218

Departments of aMolecular Medicine and Surgery, Neurogenetics Unit bNeurobiology, Care Sciences and Society, Centre for Family Medicine cClinical Neuroscience dMolecular Medicine and Surgery, Endocrine and Diabetes Unit eMedicine, Cardiovascular Medicine Unit, Karolinska Institutet fCenter for Molecular Medicine, Karolinska University Hospital Solna gDepartment of Adult Psychiatry, PRIMA Barn och Vuxenpsykiatri AB hChild and Adolescent Psychiatry Research Center, Stockholm, Sweden.

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http://dx.doi.org/10.1097/YPG.0000000000000181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662154PMC
December 2017

Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts.

Int J Biochem Cell Biol 2017 10 12;91(Pt A):9-13. Epub 2017 Aug 12.

Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.07.021DOI Listing
October 2017

Perilipin 5 is protective in the ischemic heart.

Int J Cardiol 2016 Sep 16;219:446-54. Epub 2016 Jun 16.

Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden; Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.06.037DOI Listing
September 2016

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

Arterioscler Thromb Vasc Biol 2016 09 28;36(9):1947-61. Epub 2016 Jul 28.

From the Departments of Molecular Medicine and Surgery (L.P.M., U.R., A.R., M.L., I.E., S.R., M.K., S.A., J.R., U.H.), Medicine (M.S.-L., J.M., V.P., Y.L., H.J., M.G.D., L.M., E.E., G.P.-B., G.K.H., P.E., A.H.), Division of Cardiovascular Epidemiology, Institute of Environmental Medicine (U.d.F.), and Department of Clinical Neuroscience, Center for Molecular Medicine (V.V.), Karolinska Institutet, Solna, Sweden; Division of Vascular Surgery, Stanford University, CA (C.L.M., T.Q.); Science for Life Laboratory, Solna, Sweden (M.V., J.L.); Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Italy (D.B., E.T.); Dipartimento di Scienze Cliniche e di Comunità, Centro Cardiologico Monzino, IRCCS, Milan, Italy (D.B., F.V., E.T.); British Heart Foundation Laboratories, Department of Medicine, University College of London, United Kingdom (S.E.H.); Department of Cardiology, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden (U.d.F.); Science for Life Laboratory, Department of Proteomics, Stockholm, Sweden (J.O.); and Department of Vascular Surgery, Leiden University Medical Center, The Netherlands (J.H.N.L.).

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http://dx.doi.org/10.1161/ATVBAHA.116.307893DOI Listing
September 2016

MicroRNA 486-3P as a stability marker in acute coronary syndrome.

Biosci Rep 2016 07 30;36(3). Epub 2016 Jun 30.

Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1042/BSR20160023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293558PMC
July 2016

Melatonin receptor 1B gene associated with hyperglycemia in bipolar disorder.

Psychiatr Genet 2016 Jun;26(3):136-9

aNeurogenetics Unit, Department of Molecular Medicine and Surgery bDepartment of Clinical Neuroscience cEndocrine and Diabetes Unit, Department of Molecular Medicine and Surgery dCardiovascular Medicine Unit, Department of Medicine eDepartment of Neurobiology, Care Sciences and Society, Centre for Family Medicine fCentre for Psychiatric Research and Education, Karolinska Institutet gCenter for Molecular Medicine, Karolinska University Hospital Solna hChild and Adolescent Psychiatry Research Center, Stockholm iDepartment of Clinical Sciences, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1097/YPG.0000000000000131DOI Listing
June 2016

A Case-Control Study of Risk Markers and Mortality in Takotsubo Stress Cardiomyopathy.

J Am Coll Cardiol 2016 Apr;67(16):1931-6

Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden; Söder-sjukhuset, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jacc.2016.02.029DOI Listing
April 2016

ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability.

Arterioscler Thromb Vasc Biol 2015 May 12;35(5):1226-35. Epub 2015 Mar 12.

From the Atherosclerosis Research Unit, Department of Medicine, Center for Molecular Medicine, Karolinska University Hospital (J.M., P.G., H.J., L.M., P.E., E.E.), Division of Clinical Research Center, Department of Laboratory Medicine (K.H.), Division of Renal Medicine, Department of Clinical Science, Technology and Intervention (A.W.), Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery (A.F.-C.), Karolinska Institutet, Stockholm, Sweden; Wihuri Research Institute, Helsinki, Finland (P.T.K.); and Experimental Cardiovascular Research Group and Cardiology Department, Skåne University Hospital, Clinical Research Center, Clinical Sciences Malmö, Lund University, Sweden (I.G.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304840DOI Listing
May 2015

Peroxisome proliferator-activated receptor delta and cardiovascular disease.

Atherosclerosis 2013 Nov 5;231(1):95-106. Epub 2013 Sep 5.

Atherosclerosis Research Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.08.027DOI Listing
November 2013

MicroRNA-9 regulates the expression of peroxisome proliferator-activated receptor δ in human monocytes during the inflammatory response.

Int J Mol Med 2013 May 20;31(5):1003-10. Epub 2013 Mar 20.

Atherosclerosis Research Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital L8:03, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.3892/ijmm.2013.1311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658603PMC
May 2013

Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed.

Biochem Biophys Res Commun 2012 Aug 20;425(2):138-43. Epub 2012 Jul 20.

Department of Medical Biosciences, Physiological Chemistry Umeå University, SE-901 87 Umeå, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2012.07.048DOI Listing
August 2012

European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011.

Atherosclerosis 2012 Mar 11;221(1):287-93. Epub 2011 Dec 11.

Dipartimento di Scienze Farmacologiche, Biologiche e Chimiche Applicate, Universita 'di Parma, 43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.12.002DOI Listing
March 2012

Stereotyping at the undergraduate level revealed during interprofessional learning between future doctors and biomedical scientists.

J Interprof Care 2010 Jan;24(1):53-62

Department of Molecular Medicine & Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://www.tandfonline.com/doi/full/10.3109/1356182090292170
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http://dx.doi.org/10.3109/13561820902921704DOI Listing
January 2010

IGFBP-1 protease activity and IGFBP-1 fragments in a patient with multiple myeloma.

Growth Horm IGF Res 2009 Dec 17;19(6):507-12. Epub 2009 Jun 17.

Department of Molecular Medicine and Surgery, Karolinska Institutet, L1:01 Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ghir.2009.05.002DOI Listing
December 2009

Regulation of skeletal muscle physiology and metabolism by peroxisome proliferator-activated receptor delta.

Pharmacol Rev 2009 Sep;61(3):373-93

Atherosclerosis Research Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://pharmrev.aspetjournals.org/cgi/doi/10.1124/pr.109.001
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http://dx.doi.org/10.1124/pr.109.001560DOI Listing
September 2009

PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function.

Curr Opin Lipidol 2009 Aug;20(4):333-6

Oxford Centre for Diabetes, Endocrinology and Metabolism, Nuffield Department of Clinical Medicine, University of Oxford, UK.

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http://dx.doi.org/10.1097/MOL.0b013e32832dd4b1DOI Listing
August 2009

PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes.

Toxicol Appl Pharmacol 2008 Aug 26;231(1):1-9. Epub 2008 Mar 26.

Atherosclerosis Research Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.taap.2008.03.007DOI Listing
August 2008

PPARdelta increases expression of the human apolipoprotein A-II gene in human liver cells.

Int J Mol Med 2008 Jun;21(6):819-24

Atherosclerosis Research Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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June 2008

Alternative splicing of human peroxisome proliferator-activated receptor delta (PPAR delta): effects on translation efficiency and trans-activation ability.

BMC Mol Biol 2007 Aug 16;8:70. Epub 2007 Aug 16.

The Atherosclerosis Research Unit, King Gustaf V Research Institute, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1471-2199-8-70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045109PMC
August 2007

Open-ended assignments and student responsibility.

Biochem Mol Biol Educ 2007 May;35(3):187-92

From the Department of Clinical Microbiology, Microbiology and Tumorbiology Center, Karolinska University Hospital, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1002/bmb.49DOI Listing
May 2007

Promoter analysis of the murine squalene epoxidase gene. Identification of a 205 bp homing region regulated by both SREBP'S and NF-Y.

Biochim Biophys Acta 2006 Oct 1;1761(10):1213-27. Epub 2006 Sep 1.

Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska University Hospital, 14186 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbalip.2006.08.015DOI Listing
October 2006

Acquired obesity increases CD68 and tumor necrosis factor-alpha and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins.

J Clin Endocrinol Metab 2006 Jul 11;91(7):2776-81. Epub 2006 Apr 11.

M.Sc., Obesity Research Unit, Biomedicum Helsinki, C428a, P.O. Box 700, FIN-00029 HUS, Finland.

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http://dx.doi.org/10.1210/jc.2005-2848DOI Listing
July 2006

A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein.

Biochim Biophys Acta 2005 Apr;1728(1-2):95-104

MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, UK.

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http://dx.doi.org/10.1016/j.bbaexp.2005.01.017DOI Listing
April 2005

Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins.

J Clin Endocrinol Metab 2004 Sep;89(9):4414-21

Department of Medicine, Atherosclerosis Research Unit, King Gustaf V Research Institute, Karolinska Institutet, S-17176 Stockholm, Sweden.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2004-0153DOI Listing
September 2004

Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy.

Am J Physiol Endocrinol Metab 2004 Jun 28;286(6):E941-9. Epub 2004 Jan 28.

Division of Diabetes, Department of Medicine, Helsinki University Central Hospital, PO Box 348, FIN-00029 HUS, Helsinki, Finland.

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http://dx.doi.org/10.1152/ajpendo.00490.2003DOI Listing
June 2004

Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines.

Cancer Res 2004 May;64(9):3162-70

Biomedical Research Centre and Cancer Research United Kingdom Molecular Pharmacology Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, United Kingdom.

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May 2004

PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells.

Biochem Biophys Res Commun 2003 Aug;308(2):361-8

King Gustaf V Research Institute, Karolinska Institutet, Karolinska Hospital, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/s0006-291x(03)01384-6DOI Listing
August 2003

Evidence that peroxisome proliferator-activated receptor delta influences cholesterol metabolism in men.

Arterioscler Thromb Vasc Biol 2003 Apr 27;23(4):637-43. Epub 2003 Feb 27.

Atherosclerosis Research Unit, King Gustaf V Research Institute, Karolinska Hospital, SE-171 76 Stockholm, Sweden.

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http://atvb.ahajournals.org/content/23/4/637.full.pdf
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http://atvb.ahajournals.org/cgi/doi/10.1161/01.ATV.000006438
Publisher Site
http://dx.doi.org/10.1161/01.ATV.0000064383.88696.24DOI Listing
April 2003

Troglitazone stimulates IGF-binding protein-1 by a PPAR gamma-independent mechanism.

Biochem Biophys Res Commun 2003 Apr;303(2):693-9

Department of Molecular Medicine, Karolinska Institutet and Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/s0006-291x(03)00403-0DOI Listing
April 2003

Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.

Atherosclerosis 2003 Apr;167(2):311-7

Atherosclerosis Research Unit, King Gustaf V Research Institute, Karolinska Hospital, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/s0021-9150(03)00016-9DOI Listing
April 2003

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.

J Lipid Res 2002 Jan;43(1):51-8

King Gustaf V Research Institute, Karolinska Hospital, SE-171 76, Stockholm, Sweden.

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January 2002