Evelien Smits

Evelien Smits

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Evelien Smits

Publications by authors named "Evelien Smits"

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New targets for therapy: antigen identification in adults with B-cell acute lymphoblastic leukaemia.

Cancer Immunol Immunother 2020 May 22;69(5):867-877. Epub 2020 Jan 22.

Department of Biomedical Sciences, University of Hull, Cottingham Road, Hardy Building, Room 111, Hull, HU7 6RX, UK.

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http://dx.doi.org/10.1007/s00262-020-02484-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183504PMC
May 2020

The potential and controversy of targeting STAT family members in cancer.

Semin Cancer Biol 2020 Feb 9;60:41-56. Epub 2019 Oct 9.

Multidisciplinary Oncologic Centre Antwerp (MOCA), Antwerp University Hospital, Wilrijkstraat 10, Edegem, B-2650, Belgium; Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, Wilrijk, B-2610, Belgium; Gynaecologic Oncology Unit, Antwerp University Hospital, Wilrijkstraat 10, Edegem, B-2650, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.10.002DOI Listing
February 2020

Ribonucleic Acid Engineering of Dendritic Cells for Therapeutic Vaccination: Ready 'N Able to Improve Clinical Outcome?

Cancers (Basel) 2020 Jan 27;12(2). Epub 2020 Jan 27.

Laboratory of Experimental Hematology, VAXINFECTIO, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.

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http://dx.doi.org/10.3390/cancers12020299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072269PMC
January 2020

Modifying the Tumour Microenvironment: Challenges and Future Perspectives for Anticancer Plasma Treatments.

Cancers (Basel) 2019 Dec 2;11(12). Epub 2019 Dec 2.

PLASMANT, Chemistry Department, University of Antwerp, 2610 Antwerp, Belgium.

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http://dx.doi.org/10.3390/cancers11121920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966454PMC
December 2019

Dendritic Cell-Based and Other Vaccination Strategies for Pediatric Cancer.

Cancers (Basel) 2019 Sep 19;11(9). Epub 2019 Sep 19.

Center for Cell Therapy & Regenerative Medicine, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, Antwerp, Belgium.

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http://dx.doi.org/10.3390/cancers11091396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770385PMC
September 2019

CD56 Homodimerization and Participation in Anti-Tumor Immune Effector Cell Functioning: A Role for Interleukin-15.

Cancers (Basel) 2019 Jul 22;11(7). Epub 2019 Jul 22.

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.

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http://dx.doi.org/10.3390/cancers11071029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678613PMC
July 2019

Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion.

Front Immunol 2018 10;9:658. Epub 2018 Apr 10.

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Faculty of Medicine and Health Sciences, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.3389/fimmu.2018.00658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902500PMC
June 2019

Dendritic Cells and Programmed Death-1 Blockade: A Joint Venture to Combat Cancer.

Front Immunol 2018 1;9:394. Epub 2018 Mar 1.

Laboratory of Experimental Hematology, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.3389/fimmu.2018.00394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863527PMC
May 2019

Memory CD4 T cell receptor repertoire data mining as a tool for identifying cytomegalovirus serostatus.

Genes Immun 2019 03 15;20(3):255-260. Epub 2018 Jun 15.

AUDACIS, Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1038/s41435-018-0035-yDOI Listing
March 2019

Non-Thermal Plasma as a Unique Delivery System of Short-Lived Reactive Oxygen and Nitrogen Species for Immunogenic Cell Death in Melanoma Cells.

Adv Sci (Weinh) 2019 Mar 28;6(6):1802062. Epub 2019 Jan 28.

Plasma, Laser Ablation, and Surface Modeling-Antwerp (PLASMANT) University of Antwerp Universiteitsplein 1 2610 Antwerpen-Wilrijk Belgium.

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http://dx.doi.org/10.1002/advs.201802062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425452PMC
March 2019

Transcriptome profiling in blood before and after hepatitis B vaccination shows significant differences in gene expression between responders and non-responders.

Vaccine 2018 10 8;36(42):6282-6289. Epub 2018 Sep 8.

Department of Medical Genetics, University of Antwerp/Antwerp University Hospital, Edegem, Belgium; AUDACIS, Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp, Antwerp, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X183123
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http://dx.doi.org/10.1016/j.vaccine.2018.09.001DOI Listing
October 2018

Natural killer cells and their therapeutic role in pancreatic cancer: A systematic review.

Pharmacol Ther 2018 09 13;189:31-44. Epub 2018 Apr 13.

Center for Oncological Research, University of Antwerp, Antwerp, Belgium; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Antwerp, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S01637258183006
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http://dx.doi.org/10.1016/j.pharmthera.2018.04.003DOI Listing
September 2018

BDCA1+CD14+ Immunosuppressive Cells in Cancer, a Potential Target?

Vaccines (Basel) 2018 Sep 19;6(3). Epub 2018 Sep 19.

Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen 6525 GA, The Netherlands.

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http://dx.doi.org/10.3390/vaccines6030065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161086PMC
September 2018

Author Correction: Multidisciplinary study of the secondary immune response in grandparents re-exposed to chickenpox.

Sci Rep 2018 Jul 12;8(1):10824. Epub 2018 Jul 12.

Centre for Health Economics Research & Modeling Infectious Diseases (CHERMID), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1038/s41598-018-28930-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043574PMC
July 2018

The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy.

Cytokine Growth Factor Rev 2018 06 16;41:54-64. Epub 2018 May 16.

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.cytogfr.2018.05.002DOI Listing
June 2018

Combining top-ranked immunotherapeutics in lung cancer.

Lancet Oncol 2018 05 5;19(5):592-594. Epub 2018 Apr 5.

Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Antwerp, Belgium; Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1016/S1470-2045(18)30186-4DOI Listing
May 2018

Vaccine and immune cell therapy in non-small cell lung cancer.

J Thorac Dis 2018 May;10(Suppl 13):S1602-S1614

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.

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http://dx.doi.org/10.21037/jtd.2018.05.134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994506PMC
May 2018

Anti-cancer capacity of plasma-treated PBS: effect of chemical composition on cancer cell cytotoxicity.

Sci Rep 2017 11 28;7(1):16478. Epub 2017 Nov 28.

Research group PLASMANT, Department of Chemistry, University of Antwerp Universiteitsplein 1, BE-2610, Wilrijk-Antwerp, Belgium.

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http://dx.doi.org/10.1038/s41598-017-16758-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705646PMC
November 2017

CD70 and PD-L1 in anaplastic thyroid cancer - promising targets for immunotherapy.

Histopathology 2017 Sep 16;71(3):357-365. Epub 2017 Jun 16.

Department of Pathology, Antwerp University Hospital, Edegem, Belgium.

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http://dx.doi.org/10.1111/his.13230DOI Listing
September 2017

Monocyte-Derived Dendritic Cells with Silenced PD-1 Ligands and Transpresenting Interleukin-15 Stimulate Strong Tumor-Reactive T-cell Expansion.

Cancer Immunol Res 2017 08 21;5(8):710-715. Epub 2017 Jun 21.

Laboratory of Hematology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1158/2326-6066.CIR-16-0336DOI Listing
August 2017

CD56 in the Immune System: More Than a Marker for Cytotoxicity?

Front Immunol 2017 24;8:892. Epub 2017 Jul 24.

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Faculty of Medicine and Health Sciences, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.3389/fimmu.2017.00892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522883PMC
July 2017

Dendritic Cells as Vaccines: Key Regulators of Tolerance and Immunity.

Mediators Inflamm 2016 31;2016:5789725. Epub 2016 May 31.

Department of Laboratory Medicine, Radboudumc, Nijmegen, Netherlands.

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http://dx.doi.org/10.1155/2016/5789725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906213PMC
June 2017

Multidisciplinary study of the secondary immune response in grandparents re-exposed to chickenpox.

Sci Rep 2017 04 24;7(1):1077. Epub 2017 Apr 24.

Centre for Health Economics Research & Modeling Infectious Diseases (CHERMID), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1038/s41598-017-01024-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430877PMC
April 2017

IL-15 receptor alpha as the magic wand to boost the success of IL-15 antitumor therapies: The upswing of IL-15 transpresentation.

Pharmacol Ther 2017 02 21;170:73-79. Epub 2016 Oct 21.

Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine & Health Sciences, University of Antwerp, Antwerp, Belgium; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Antwerp, Belgium; Center for Oncological Research Antwerp, Faculty of Medicine & Health Sciences, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.pharmthera.2016.10.012DOI Listing
February 2017

Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells.

Oncotarget 2017 Feb;8(8):13652-13665

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium.

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http://dx.doi.org/10.18632/oncotarget.14622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355127PMC
February 2017

Generation and Cryopreservation of Clinical Grade Wilms' Tumor 1 mRNA-Loaded Dendritic Cell Vaccines for Cancer Immunotherapy.

Methods Mol Biol 2016 ;1393:27-35

Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, D.T.431, Wilrijk, Antwerp, 2610, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-3338-9_3DOI Listing
December 2016

Prognostic and predictive aspects of the tumor immune microenvironment and immune checkpoints in malignant pleural mesothelioma.

Oncoimmunology 2017 28;6(1):e1261241. Epub 2016 Nov 28.

Center for Oncological Research, University of Antwerp, Antwerp, Belgium; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1080/2162402X.2016.1261241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283621PMC
November 2016

Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells.

J Hematol Oncol 2016 Sep 29;9(1):101. Epub 2016 Sep 29.

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041439PMC
http://dx.doi.org/10.1186/s13045-016-0329-3DOI Listing
September 2016

Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity.

Oncoimmunology 2016 2;5(10):e1227902. Epub 2016 Sep 2.

Department of Tumor Immunology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences , Nijmegen, the Netherlands.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2016.1
Publisher Site
http://dx.doi.org/10.1080/2162402X.2016.1227902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087293PMC
September 2016

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect.

J Immunol Res 2015 29;2015:158038. Epub 2015 Oct 29.

Center for Oncological Research, University of Antwerp, 2610 Wilrijk, Belgium ; Department of Pathology, Antwerp University Hospital, 2650 Edegem, Belgium.

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http://dx.doi.org/10.1155/2015/158038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641952PMC
August 2016

Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines.

Cancer Res 2016 08 20;76(15):4332-46. Epub 2016 Jun 20.

Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands. Department of Medical Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1695DOI Listing
August 2016

Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis.

PLoS One 2015 22;10(10):e0140483. Epub 2015 Oct 22.

Cancer Sciences Unit (MP824), Somers Cancer Sciences Building, University of Southampton, Southampton, United Kingdom; Department of Life Sciences, University of Bedfordshire, Park Square, Luton, United Kingdom; Department of Haematological Medicine, King's College London School of Medicine, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140483PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619595PMC
June 2016

Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner.

PLoS One 2015 7;10(5):e0123340. Epub 2015 May 7.

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123340PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423923PMC
February 2016

Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials.

Pharmacol Ther 2016 Feb 23;158:24-40. Epub 2015 Nov 23.

Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.pharmthera.2015.11.008DOI Listing
February 2016

Targeting immune checkpoints: New opportunity for mesothelioma treatment?

Cancer Treat Rev 2015 Dec 28;41(10):914-24. Epub 2015 Sep 28.

Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium; Laboratory of Experimental Hematology, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2015.09.006DOI Listing
December 2015

Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity.

Oncotarget 2015 Dec;6(42):44123-33

Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.18632/oncotarget.6536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792546PMC
December 2015

Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation.

Oncoimmunology 2015 Nov 27;4(11):e1023973. Epub 2015 May 27.

U-DANCE; Laboratory for Translational Immunology; UMC Utrecht ; Utrecht, The Netherlands ; U-DAIR; LTI; UMC Utrecht ; Utrecht, The Netherlands.

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http://dx.doi.org/10.1080/2162402X.2015.1023973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589057PMC
November 2015

Dendritic Cells as Pharmacological Tools for Cancer Immunotherapy.

Pharmacol Rev 2015 Oct;67(4):731-53

Faculty of Medicine and Health Sciences, Vaccine & Infectious Disease Institute, Laboratory of Experimental Hematology, Tumor Immunology Group (S.A., H.H.V.A., H.G., E.L., V.F.V.T., Z.N.B.), and Faculty of Medicine and Health Sciences, Center for Oncological Research (E.L.S.), University of Antwerp, Antwerp, Belgium; Center for Cell Therapy & Regenerative Medicine, Antwerp University Hospital, Antwerp, Belgium (S.A., E.L.S., Z.N.B.); and ANZAC Research Institute, Dendritic Cell Biology and Therapeutics Group, University of Sydney, Sydney, New South Wales, Australia (C.B., P.D.F.).

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http://dx.doi.org/10.1124/pr.114.009456DOI Listing
October 2015

Plasma, blood and liver tissue sample preparation methods for the separate quantification of liposomal-encapsulated prednisolone phosphate and non-encapsulated prednisolone.

J Liposome Res 2015 Mar 1;25(1):46-57. Epub 2014 Jul 1.

Pharmaceutical Sciences and Clinical Supply , MSD Oss BV, Oss , The Netherlands and.

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http://dx.doi.org/10.3109/08982104.2014.928887DOI Listing
March 2015

Poly(I:C) as cancer vaccine adjuvant: knocking on the door of medical breakthroughs.

Pharmacol Ther 2015 Feb 2;146:120-31. Epub 2014 Oct 2.

Center for Oncological Research, University of Antwerp, B-2610 Antwerp, Belgium; Tumor Immunology Group, Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, B-2650 Edegem, Belgium; Center for Cell Therapy & Regenerative Medicine, Antwerp University Hospital, B-2650 Edegem, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2014.09.010DOI Listing
February 2015

Interleukin-15: new kid on the block for antitumor combination therapy.

Cytokine Growth Factor Rev 2015 Feb 28;26(1):15-24. Epub 2014 Sep 28.

Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine & Health Sciences, University of Antwerp, Antwerp, Belgium; Center for Oncological Research Antwerp, Faculty of Medicine & Health Sciences, University of Antwerp, Antwerp, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2014.09.001DOI Listing
February 2015

Induction of cytomegalovirus-specific T cell responses in healthy volunteers and allogeneic stem cell recipients using vaccination with messenger RNA-transfected dendritic cells.

Transplantation 2015 Jan;99(1):120-7

1 Department of Nephrology-Hypertension, Antwerp University Hospital, Edegem, Belgium. 2 Laboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium. 3 Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium. 4 Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Edegem, Belgium. 5 Department of Hematology, Antwerp University Hospital, Edegem, Belgium. 6 Centre for the Evaluation of Vaccination (CEV), Vaccine & Infectious Disease Institute (Vaxinfectio), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium. 7 Department of Microbiology, Antwerp University Hospital, Edegem, Belgium.

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http://dx.doi.org/10.1097/TP.0000000000000272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281162PMC
January 2015

Loading of acute myeloid leukemia cells with poly(I:C) by electroporation.

Methods Mol Biol 2014 ;1139:233-41

Tumor Immunology Group, Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-0345-0_20DOI Listing
November 2014

Immunotherapy: is a minor god yet in the pantheon of treatments for lung cancer?

Expert Rev Anticancer Ther 2014 Oct 22;14(10):1173-87. Epub 2014 Aug 22.

Oncology Department, Phase I - Early Clinical Trials Unit, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, Belgium.

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http://dx.doi.org/10.1586/14737140.2014.952287DOI Listing
October 2014

HPV vaccine stimulates cytotoxic activity of killer dendritic cells and natural killer cells against HPV-positive tumour cells.

J Cell Mol Med 2014 Jul 30;18(7):1372-80. Epub 2014 Jun 30.

Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine & Health Sciences, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1111/jcmm.12284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124021PMC
July 2014

In vitro confirmation of the quantitative differentiation of liposomal encapsulated and non-encapsulated prednisolone (phosphate) tissue concentrations by murine phosphatases.

J Liposome Res 2014 Jun 5;24(2):130-5. Epub 2013 Nov 5.

Pharmaceutical Sciences and Clinical Supply , MSD Oss BV, Oss , The Netherlands and.

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http://dx.doi.org/10.3109/08982104.2013.850593DOI Listing
June 2014

Clinical use of dendritic cells for cancer therapy.

Lancet Oncol 2014 Jun;15(7):e257-67

Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Edegem, Belgium; Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium.

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http://dx.doi.org/10.1016/S1470-2045(13)70585-0DOI Listing
June 2014

Influence of frequent infectious exposures on general and varicella-zoster virus-specific immune responses in pediatricians.

Clin Vaccine Immunol 2014 Mar 15;21(3):417-26. Epub 2014 Jan 15.

Centre for Health Economics Research and Modeling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1128/CVI.00818-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957663PMC
March 2014

Tumoricidal activity of human dendritic cells.

Trends Immunol 2014 Jan 18;35(1):38-46. Epub 2013 Nov 18.

Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Department of Medical Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.it.2013.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106406PMC
January 2014

Interleukin-15 dendritic cells as vaccine candidates for cancer immunotherapy.

Hum Vaccin Immunother 2013 Sep 18;9(9):1956-61. Epub 2013 Jun 18.

Vaccine & Infectious Disease Institute; Laboratory of Experimental Hematology; Tumor Immunology Group (TIGR); University of Antwerp; Antwerp, Belgium; Center for Cell Therapy & Regenerative Medicine; Antwerp University Hospital; Antwerp, Belgium.

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http://dx.doi.org/10.4161/hv.25373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906362PMC
September 2013

NK cells: key to success of DC-based cancer vaccines?

Oncologist 2012 20;17(10):1256-70. Epub 2012 Aug 20.

Vaccine & Infectious Disease Institute (Vaxinfectio), Laboratory of Experimental Hematology, TIGR, University of Antwerp (UA), Antwerp University Hospital (UZA), Wilrijkstraat 10, B-2650 Antwerp, Belgium.

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http://dx.doi.org/10.1634/theoncologist.2011-0122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481891PMC
June 2013

Interleukin-15-induced CD56(+) myeloid dendritic cells combine potent tumor antigen presentation with direct tumoricidal potential.

PLoS One 2012 28;7(12):e51851. Epub 2012 Dec 28.

University of Antwerp, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Antwerp, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051851PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532168PMC
June 2013

Interferon α may be back on track to treat acute myeloid leukemia.

Oncoimmunology 2013 Apr;2(4):e23619

Tumor Immunology Group, Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium ; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Antwerp, Belgium.

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http://dx.doi.org/10.4161/onci.23619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654584PMC
April 2013

Sampling site matters when counting lymphocyte subpopulations.

PLoS One 2012 25;7(7):e41405. Epub 2012 Jul 25.

Centre for Health Economics Research and Modeling Infectious Diseases, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041405PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405139PMC
March 2013

The development of a method to quantify encapsulated and free prednisolone phosphate in liposomal formulations.

J Pharm Biomed Anal 2013 Mar 21;75:47-54. Epub 2012 Nov 21.

Pharmaceutical Sciences and Clinical Supply, MSD Oss BV, Oss, The Netherlands.

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http://dx.doi.org/10.1016/j.jpba.2012.11.008DOI Listing
March 2013

CD56 marks human dendritic cell subsets with cytotoxic potential.

Oncoimmunology 2013 Feb;2(2):e23037

Vaccine and Infectious Disease Institute (VAXINFECTIO); Laboratory of Experimental Hematology; University of Antwerp; Antwerp, Belgium.

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http://dx.doi.org/10.4161/onci.23037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601173PMC
February 2013

Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities.

Blood 2012 Nov 10;120(19):3936-44. Epub 2012 Sep 10.

Department of Tumor Immunology, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2012-06-435941DOI Listing
November 2012

Dendritic cell vaccination in acute myeloid leukemia.

Cytotherapy 2012 Jul;14(6):647-56

University of Antwerp, Vaccine & Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Wilrijk, Antwerp, Belgium.

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http://dx.doi.org/10.3109/14653249.2012.693744DOI Listing
July 2012

Poly(I:C) enhances the susceptibility of leukemic cells to NK cell cytotoxicity and phagocytosis by DC.

PLoS One 2011 17;6(6):e20952. Epub 2011 Jun 17.

Vaccine & Infectious Disease Institute (Vaxinfectio), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Antwerp, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020952PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117863PMC
November 2011

Dendritic cells in the pathogenesis and treatment of human diseases: a Janus Bifrons?

Immunotherapy 2011 Oct;3(10):1203-22

Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (Vaxinfectio), University of Antwerp, B-2610 Wilrijk, Belgium.

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http://dx.doi.org/10.2217/imt.11.110DOI Listing
October 2011

Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia.

Cancer Immunol Immunother 2011 Jun 26;60(6):757-69. Epub 2011 Apr 26.

Laboratory of Experimental Haematology, Vaccine and Infectious Disease Institute, Antwerp University Hospital, University of Antwerp, Wilrijkstraat 10, 2650, Antwerp, Belgium.

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http://dx.doi.org/10.1007/s00262-011-1022-6DOI Listing
June 2011

Dendritic cell vaccine therapy for acute myeloid leukemia: questions and answers.

Hum Vaccin 2011 May 1;7(5):579-84. Epub 2011 May 1.

University of Antwerp, Vaccine & Infectious Disease Institute-Laboratory of Experimental Hematology, Wilrijk (Antwerp), Belgium.

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http://dx.doi.org/10.4161/hv.7.5.14652DOI Listing
May 2011

Exploring the impact of exposure to primary varicella in children on varicella-zoster virus immunity of parents.

Viral Immunol 2011 Apr;24(2):151-7

Centre for Health Economics Research and Modeling Infectious Diseases (CHERMID), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1089/vim.2010.0031DOI Listing
April 2011

The effect of apoptotic cells on virus-specific immune responses detected using IFN-gamma ELISPOT.

J Immunol Methods 2010 May 6;357(1-2):51-4. Epub 2010 Mar 6.

Laboratory of Experimental Hematology, Vaccine & Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, B-2650 Edegem, Belgium.

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http://download.bioon.com.cn/upload/month_1007/20100705_fe17
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http://linkinghub.elsevier.com/retrieve/pii/S002217591000050
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http://dx.doi.org/10.1016/j.jim.2010.03.001DOI Listing
May 2010

The Toll-like receptor 7/8 agonist resiquimod greatly increases the immunostimulatory capacity of human acute myeloid leukemia cells.

Cancer Immunol Immunother 2010 Jan 16;59(1):35-46. Epub 2009 May 16.

Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1007/s00262-009-0721-8DOI Listing
January 2010

Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties.

J Transl Med 2009 Dec 18;7:109. Epub 2009 Dec 18.

University of Antwerp - Faculty of Medicine, Vaccine & Infectious Disease Institute (Vaxinfectio), Laboratory of Experimental Hematology, Universiteitsplein 1, B-2610 Wilrijk (Antwerp), Belgium.

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http://translational-medicine.biomedcentral.com/articles/10.
Publisher Site
http://dx.doi.org/10.1186/1479-5876-7-109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807857PMC
December 2009

Dendritic cell-based cancer gene therapy.

Hum Gene Ther 2009 Oct;20(10):1106-18

Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, B-2610 Wilrijk (Antwerp), Belgium.

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http://dx.doi.org/10.1089/hum.2009.145DOI Listing
October 2009

Acute myeloid leukemic cell lines loaded with synthetic dsRNA trigger IFN-gamma secretion by human NK cells.

Leuk Res 2009 Apr 9;33(4):539-46. Epub 2008 Oct 9.

Vaccine & Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, Antwerp University, Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.leukres.2008.08.020DOI Listing
April 2009

Immunotherapy of acute myeloid leukemia: current approaches.

Oncologist 2009 Mar 16;14(3):240-52. Epub 2009 Mar 16.

Vaccine & Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1634/theoncologist.2008-0165DOI Listing
March 2009

The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy.

Oncologist 2008 Aug 13;13(8):859-75. Epub 2008 Aug 13.

Vaccine & Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1634/theoncologist.2008-0097DOI Listing
August 2008

Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women.

Int J Cancer 2004 Jan;108(2):258-61

Department of Medical Oncology, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1002/ijc.11543DOI Listing
January 2004