Publications by authors named "Evan Y Snyder"

100Publications

Nna1 gene deficiency triggers Purkinje neuron death by tubulin hyperglutamylation and ER dysfunction.

JCI Insight 2020 10 2;5(19). Epub 2020 Oct 2.

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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October 2020

"Reprogram Enablement" as an Assay for Identifying Early Oncogenic Pathways by Their Ability to Allow Neoplastic Cells to Reacquire an Epiblast State.

Stem Cell Reports 2020 09 13;15(3):761-775. Epub 2020 Aug 13.

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA; Department of Pediatrics, University of California, La Jolla, CA, USA. Electronic address:

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September 2020

Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells.

Curr Protoc Stem Cell Biol 2020 09;54(1):e119

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.

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September 2020

The Evolution of Stem Cells, Disease Modeling, and Drug Discovery for Neurological Disorders.

Stem Cells Dev 2020 Sep 6;29(17):1131-1141. Epub 2020 May 6.

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA.

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September 2020

Stem Cell Composition of Umbilical Cord Blood Following Milking Compared with Delayed Clamping of the Cord Appears Better Suited for Promoting Hematopoiesis.

J Pediatr 2020 01 27;216:222-226. Epub 2019 Aug 27.

Department of Pediatrics, University of California San Diego, La Jolla, CA; Center for Stem Cells and Regenerative Medicine, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA; Sanford Consortium for Regenerative Medicine, La Jolla, CA. Electronic address:

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January 2020

Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness.

Cell Rep 2019 08;28(8):2064-2079.e11

Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Neurological Surgery and Brain Tumor Research Center, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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August 2019

Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice.

Cell Transplant 2018 08 11;27(8):1249-1255. Epub 2018 Jul 11.

1 School of Life Sciences, Tsinghua University, Beijing, China.

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August 2018

The state of the art in stem cell biology and regenerative medicine: the end of the beginning.

Authors:
Evan Y Snyder

Pediatr Res 2018 01 13;83(1-2):191-204. Epub 2017 Dec 13.

Center for Stem Cells & Regenerative Medicine, Sanford Burnham Prebys Medical Discovery Institute and Department of Pediatrics, University of California-San Diego, La Jolla, California.

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January 2018

Finding a new purpose for old drugs.

Authors:
Evan Y Snyder

Science 2017 09;357(6354):869-870

Sanford Burnham Prebys Medical Discovery Institute and Department of Pediatrics, University of California-San Diego, La Jolla, CA 92037, USA.

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September 2017

Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells.

Neurosurgery 2016 Sep;79(3):481-91

‡Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; §Division of SCI Research, Veterans Affairs Boston Healthcare System, Boston, Massachusetts; ¶Medical Research Institute, Chung-Ang University College of Medicine, Seoul, Korea; ‖Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; #Stem Cell Center, Sanford-Burnham Medical Research Institute, La Jolla, California; **Department of Medicine, University of British Columbia, Vancouver, BC, Canada; ‡‡Department of PM&R, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, Massachusetts.

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September 2016

hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature.

Stem Cell Reports 2015 Jun 21;4(6):1075-88. Epub 2015 May 21.

Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037, USA; Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

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June 2015

Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

Stem Cells Transl Med 2015 Mar 3;4(3):217-23. Epub 2015 Feb 3.

Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation and Harvard Stem Cell Institute, Cambridge, Massachusetts; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA; Saïd Business School, University of Oxford, Oxford, United Kingdom; Centre for Behavioural Medicine, UCL School of Pharmacy, University College London, London, United Kingdom; Stanford-UCSF FDA Center of Excellence in Regulatory Science and Innovation (CERSI), San Francisco, California, USA

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March 2015

Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies.

Cell Stem Cell 2015 Jan;16(1):13-7

Department of Biochemical Engineering, University College London, London, WC1H 0AH, UK; Department of Nanobiomedical Science and BK21 Plus NBM Global Research Center of Regenerative Medicine, Dankook University, Cheonan 330-714, Republic of Korea; Institute of Tissue Regeneration Engineering, Dankook University Graduate School, Cheonan 330-714, Republic of Korea. Electronic address:

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January 2015

Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study.

J Tissue Eng 2014 19;5:2041731414551764. Epub 2014 Sep 19.

Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK ; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation (CASMI), University of Oxford, Oxford, UK ; Harvard Stem Cell Institute, Cambridge, MA, USA ; Centre for Behavioural Medicine, UCL School of Pharmacy, University College London, London, UK.

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November 2014

Laser-assisted generation of human induced pluripotent stem cells.

Curr Protoc Stem Cell Biol 2014 Nov 3;31:4A.7.1-15. Epub 2014 Nov 3.

Stem Cell Research Center and Core Facility, Sanford-Burnham Medical Research Institute, La Jolla, California.

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November 2014

Aberrant production of tenascin-C in globoid cell leukodystrophy alters psychosine-induced microglial functions.

J Neuropathol Exp Neurol 2014 Oct;73(10):964-74

From the Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut (KIC, PNW, KMJ, AMN, AWG, AVS, EB, SJC); Stem Cells and Regenerative Biology Program, Sanford-Burnham Institute, La Jolla, California (EYS); and Department of Anatomy and Cell Biology, University of Illinois, Chicago, Illinois (ERB).

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October 2014

Special issue on stem cells: "the end of the beginning".

Exp Neurol 2014 Oct 17;260:1-2. Epub 2014 Jun 17.

Center for Stem Cells & Regenerative Medicine, Sanford-Burnham Medical Research Institute, Department of Pediatrics, University of California, San Diego, USA.

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October 2014

Generation, Expansion, and Differentiation of Human Induced Pluripotent Stem Cells (hiPSCs) Derived From the Umbilical Cords of Newborns.

Curr Protoc Stem Cell Biol 2014 May 16;29:1C.16.1-13. Epub 2014 May 16.

Department of Pediatrics, University of California at San Diego and Rady Children's Hospital, San Diego, California.

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May 2014

Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.

Stem Cells Transl Med 2014 Jun 17;3(6):692-701. Epub 2014 Apr 17.

Graduate Program in Biomedical Sciences, University of California at San Diego, La Jolla, California, USA; Program in Stem Cell and Regenerative Biology, Sanford-Burnham Medical Research Institute, La Jolla, California, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA; Departments of Psychiatry, Neurosurgery, and Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Neurology, University of Colorado School of Medicine, Denver, Colorado, USA; Department of Neurosurgery and Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts, USA; Gene Therapy Center and Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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June 2014

Reparative effects of neural stem cells in neonatal rats with hypoxic-ischemic injury are not influenced by host sex.

Pediatr Res 2014 May 24;75(5):603-11. Epub 2014 Jan 24.

1] Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, California [2] Division of Translational Studies, School of Behavioral Health, Loma Linda University School of Medicine, Loma Linda, California.

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May 2014

Homing of neural stem cells from the venous compartment into a brain infarct does not involve conventional interactions with vascular endothelium.

Stem Cells Transl Med 2014 Feb 6;3(2):229-40. Epub 2014 Jan 6.

Torrey Pines Institute for Molecular Studies, San Diego, California, USA; Sanford-Burnham Medical Research Institute, La Jolla, California, USA; America Stem Cell Inc., San Diego, California, USA; Cascade LifeSciences Inc., San Diego, California, USA.

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February 2014

Special feature on stem cells: current research and future prospects.

Exp Mol Med 2013 Nov 15;45:e63. Epub 2013 Nov 15.

Catholic High-Performance Cell Therapy Center, The Catholic University of Korea, Seoul, Korea.

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November 2013

Implications and limitations of cellular reprogramming for psychiatric drug development.

Exp Mol Med 2013 Nov 15;45:e59. Epub 2013 Nov 15.

1] Program in Stem Cell and Regenerative Biology, Sanford-Burnham Medical Research Institute, Burnham Institute for Medical Research, La Jolla, CA, USA [2] Department of Psychiatry, Veterans Administration Medical Center, La Jolla, CA, USA.

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November 2013

Repair of cartilage defects in arthritic tissue with differentiated human embryonic stem cells.

Tissue Eng Part A 2014 Feb 19;20(3-4):683-92. Epub 2013 Oct 19.

1 Shiley Center for Orthopaedic Research and Education at Scripps Health , La Jolla, California.

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February 2014

Two cells are better than one: optimizing stem cell survival by co-grafting "helper" cells that offer regulated trophic support.

Exp Neurol 2013 Sep 12;247:751-4. Epub 2013 Jul 12.

Neuroregeneration Laboratories, Neuroregeneration Laboratories, Mailman Research Center, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA.

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September 2013

Tissue plasminogen activator regulates Purkinje neuron development and survival.

Proc Natl Acad Sci U S A 2013 Jun 14;110(26):E2410-9. Epub 2013 May 14.

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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June 2013

Automated core-penumbra quantification in neonatal ischemic brain injury.

J Cereb Blood Flow Metab 2012 Dec 29;32(12):2161-70. Epub 2012 Aug 29.

Department of Pediatrics, Loma Linda University, Loma Linda, California 92350, USA.

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December 2012

Three-dimensional scaffolding to investigate neuronal derivatives of human embryonic stem cells.

Biomed Microdevices 2012 Oct;14(5):829-838

Department of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, Atkinson Hall, MC-0448, La Jolla, CA 92093, USA.

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October 2012

Stem cells and spinal cord repair.

N Engl J Med 2012 May;366(20):1940-2

Sanford-Burnham Medical Research Institute, La Jolla, CA, USA.

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May 2012

Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells.

Curr Opin Pharmacol 2011 Oct 29;11(5):521-7. Epub 2011 Jun 29.

Program in Stem Cell & Regenerative Biology, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, United States.

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October 2011

Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways.

Stem Cells Dev 2012 Mar 18;21(4):539-53. Epub 2011 Jul 18.

Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière, Université Pierre et Marie Curie-Paris 6, UMR-S975, Paris, France.

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March 2012

The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brain.

Authors:
Evan Y Snyder

Exp Neurol 2011 Jul 21;230(1):75-7. Epub 2011 Mar 21.

Sanford-Burnham Medical Research Institute, La Jolla CA 92037, USA.

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July 2011

Long-term magnetic resonance imaging of stem cells in neonatal ischemic injury.

Ann Neurol 2011 Feb 22;69(2):282-91. Epub 2010 Nov 22.

Department Radiation Medicine, Loma Linda University, CA, USA.

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February 2011

Dorsomorphin promotes human embryonic stem cell self-renewal.

Angew Chem Int Ed Engl 2011 Apr 7;50(15):3439-41. Epub 2011 Mar 7.

Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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April 2011

Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell.

Proc Natl Acad Sci U S A 2011 Mar 4;108(12):4876-81. Epub 2011 Mar 4.

Medical Research Institute, Chung-Ang University College of Medicine, 440-746 Seoul, Korea.

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March 2011

Severe Hypoxia: Consequences to Neural Stem Cells and Neurons.

J Neurol Res 2011 ;1(5)

Departments of Pediatrics, University of California San Diego, School of Medicine, USA ; Departments of Neuroscience, University of California San Diego, School of Medicine, USA ; Rady Children's Hospital-San Diego, USA.

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January 2011

Early acquisition of neural crest competence during hESCs neuralization.

PLoS One 2010 Nov 9;5(11):e13890. Epub 2010 Nov 9.

Sanford-Burnham Institute for Medical Research, La Jolla, California, United States of America.

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November 2010

Culture and manipulation of neural stem cells.

Adv Exp Med Biol 2010 ;671:13-22

Del E. Webb Neuroscience, Aging and Stem Cell Research Center, Burnham Institute for Regenerative Madicine, La Jolla, California, USA.

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June 2010

Derivation of vasculature from embryonic stem cells.

Curr Protoc Stem Cell Biol 2010 Mar;Chapter 1:Unit 1F.9

The Burnham Institute for Medical Research, La Jolla, California, USA.

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March 2010

Important precautions when deriving patient-specific neural elements from pluripotent cells.

Cytotherapy 2009 ;11(7):815-24

Department of Cell Biology and Neuroscience, University of California at Riverside, Riverside, California 92521, USA.

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June 2010

A safer stem cell: on guard against cancer.

Nat Med 2009 Sep;15(9):999-1001

Burnham Institute for Medical Research, La Jolla, California, USA.

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September 2009

Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation.

Curr Protoc Stem Cell Biol 2009 Sep;Chapter 2:Unit 2D.4

David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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September 2009

Phosphoproteomic analysis of human embryonic stem cells.

Cell Stem Cell 2009 Aug;5(2):204-13

Genomics Institute of the Novartis Research Foundation, San Diego, CA 92109, USA.

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August 2009

The dynamics of long-term transgene expression in engrafted neural stem cells.

J Comp Neurol 2009 Jul;515(1):83-92

The Burnham Institute for Medical Research, La Jolla, California 92037, USA.

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July 2009

Neuroimaging as a basis for rational stem cell therapy.

Pediatr Neurol 2009 Mar;40(3):227-36

Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, California 92354, USA.

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March 2009

Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells.

Proc Natl Acad Sci U S A 2009 Feb 4;106(8):2903-8. Epub 2009 Feb 4.

David H. Koch Center, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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February 2009

Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumors.

J Neurosci Res 2009 May;87(7):1547-55

Department of Neurosurgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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May 2009

Neural precursor cell lines promote neurite branching.

Int J Neurosci 2009 ;119(1):15-39

Center for Regenerative Medicine, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts 02114, USA.

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April 2009

Neural stem/progenitor cells modulate immune responses by suppressing T lymphocytes with nitric oxide and prostaglandin E2.

Exp Neurol 2009 Mar 9;216(1):177-83. Epub 2008 Dec 9.

Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5525, USA.

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March 2009

Preparation of autogenic human feeder cells for growth of human embryonic stem cells.

Curr Protoc Stem Cell Biol 2008 Mar;Chapter 1:Unit 1C.5.1-1C.5.15

University of California, San Diego, La Jolla, California, USA.

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March 2008

Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida.

Surgery 2008 Sep 25;144(3):367-73. Epub 2008 Jul 25.

Department of Surgery and Advanced Fetal Care Center, Children's Hospital Boston, Boston, MA 02115, USA.

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September 2008

Neural stem cell transplantation in mouse brain.

Curr Protoc Neurosci 2008 Jan;Chapter 3:Unit 3.10

Stem Cell and Regeneration Program, Center for Neuroscience and Aging Research, Burnham Institute for Medical Research, La Jolla, California, USA.

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January 2008

Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.

Exp Neurol 2008 Jun 14;211(2):362-9. Epub 2008 Feb 14.

Department of Pediatrics, Program in Neuroscience, University of Colorado Health Sciences Center, Denver, CO 80045, USA.

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June 2008

Quo vadis brain repair? A long axonal journey in the adult CNS.

Cell Stem Cell 2007 Oct;1(4):355-6

Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

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October 2007

Brain tumor stem cells and the tumor microenvironmen.

Neurosurg Focus 2008 ;24(3-4):E27

Division of Neurosurgery, University of California, San Diego, USA.

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April 2008

Stem cell-mediated regeneration of the intervertebral disc: cellular and molecular challenge.

Neurosurg Focus 2008 ;24(3-4):E21

Division of Neurosurgery, University of California, San Diego, California, USA.

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April 2008

Genetic modification of neural stem cells.

Mol Ther 2008 Mar 5;16(3):450-7. Epub 2008 Feb 5.

Division of Neurological Surgery, University of California, San Diego, California, USA.

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March 2008

Neural progenitor cell transplantation and imaging in a large animal model.

Neurosci Res 2007 Nov 23;59(3):327-40. Epub 2007 Aug 23.

Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL 36849-5525, United States.

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November 2007

Neural stem cell implantation extends life in Niemann-Pick C1 mice.

J Appl Genet 2007 ;48(3):269-72

University of Arizona, Department of Pediatrics, 1501 N. Campbell Avenue, P.O. Box 245073, Tucson, AZ 85724-5073, USA.

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October 2007

A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes.

Stem Cells 2007 Sep 7;25(9):2312-21. Epub 2007 Jun 7.

Department of Biotechnologies, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy.

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September 2007