Eva Hernando

Eva Hernando

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Eva Hernando

Eva Hernando

Publications by authors named "Eva Hernando"

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75Publications

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Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.

Cell Death Differ 2018 May 11;25(5):935-950. Epub 2017 Dec 11.

Departamento de Bioquímica, UAM, Instituto de Investigaciones Biomédicas "Alberto Sols" CSIC-UAM, Arzobispo Morcillo 4, 28029, Madrid, Spain.

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May 2018

Differential phosphorylation and n-terminal configuration of capsid subunits in parvovirus assembly and viral trafficking.

Virology 2018 05 15;518:184-194. Epub 2018 Mar 15.

Centro de Biología Molecular "Severo Ochoa" (Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid), Cantoblanco, 28049 Madrid, Spain. Electronic address:

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May 2018

miR-204-5p and miR-211-5p Contribute to BRAF Inhibitor Resistance in Melanoma.

Cancer Res 2018 Feb 11;78(4):1017-1030. Epub 2017 Dec 11.

Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CSIC), Madrid, Spain.

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February 2018

TYRP1 mRNA goes fishing for miRNAs in melanoma.

Nat Cell Biol 2017 Oct;19(11):1311-1312

Department of Pathology and Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, New York University School of Medicine, New York, New York 10016, USA.

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October 2017

A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.

Cancer Cell 2017 06;31(6):804-819.e7

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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June 2017

A TGFβ-miR-182-BRCA1 axis controls the mammary differentiation hierarchy.

Sci Signal 2016 12 6;9(457):ra118. Epub 2016 Dec 6.

Department of Radiation Oncology, New York University School of Medicine, 450 East 29th Street, New York, NY 10016, USA.

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December 2016

BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.

Cancer Med 2016 06 11;5(6):1183-93. Epub 2016 May 11.

Department of Pathology, New York University School of Medicine, New York, New York.

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June 2016

Revisiting determinants of prognosis in cutaneous melanoma.

Cancer 2015 Dec 26;121(23):4108-23. Epub 2015 Aug 26.

Department of Medical Oncology, New York University School of Medicine, New York, New York.

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December 2015

A miRNA-Based Signature Detected in Primary Melanoma Tissue Predicts Development of Brain Metastasis.

Clin Cancer Res 2015 Nov 18;21(21):4903-12. Epub 2015 Jun 18.

Department of Pathology, NYU School of Medicine, New York, NYU School of Medicine. Interdisciplinary Melanoma Cooperative Group, NYU Perlmutter Cancer Institute, NYU School of Medicine, New York, New York.

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November 2015

Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma.

Mol Cell 2015 Jul 4;59(1):75-88. Epub 2015 Jun 4.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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July 2015

The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly.

PLoS Pathog 2015 Jun 11;11(6):e1004920. Epub 2015 Jun 11.

Centro de Biología Molecular "Severo Ochoa" (Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid), Cantoblanco, Madrid, Spain.

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June 2015

Identification of metastasis-suppressive microRNAs in primary melanoma.

J Natl Cancer Inst 2015 Mar 12;107(3). Epub 2015 Feb 12.

Department of Pathology (DH, MFS, EP, XJS, FD, EH), Interdisciplinary Melanoma Cooperative Group (DH, MFS, JZ, XJS, FD, RSB, RLS, AP, IO, EH), Department of Environmental Medicine (JZ), Department of Dermatology (AP, IO), Department of Medicine (AP, IO), Department of Urology (IO); Department of Surgery (RSB, RLS), NYU Langone Medical Center, New York, NY; Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY (BB).

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March 2015

Serum-based miRNAs in the prediction and detection of recurrence in melanoma patients.

Cancer 2015 Jan 25;121(1):51-9. Epub 2014 Aug 25.

Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York; Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine, New York, New York.

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January 2015

Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes.

Cell Rep 2014 Oct 26;9(1):234-247. Epub 2014 Sep 26.

Department of Pathology, New York University School of Medicine, and Perlmutter Cancer Center, New York, NY 10016, USA; Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU Langone Medical Center, New York, NY 10016, USA. Electronic address:

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October 2014

Anti-miR182 reduces ovarian cancer burden, invasion, and metastasis: an in vivo study in orthotopic xenografts of nude mice.

Mol Cancer Ther 2014 Jul 13;13(7):1729-39. Epub 2014 May 13.

Pathology and Obstetrics and Gynecology; Robert H. Lurie Comprehensive Cancer Center, Northwestern University School of Medicine, Chicago, Illinois;

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July 2014

Clinicopathological characteristics at primary melanoma diagnosis as risk factors for brain metastasis.

Melanoma Res 2013 Dec;23(6):461-7

aDepartments of Population Health and Environmental Medicine bRonald O. Perelman Department of Dermatology cInterdisciplinary Melanoma Cooperative Group dDepartment of Pathology, New York University School of Medicine eNew York University Cancer Institute, New York, New York, USA.

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December 2013

Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo.

Pharmaceuticals (Basel) 2013 Nov 11;6(11):1429-50. Epub 2013 Nov 11.

Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA.

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November 2013

BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy.

Cancer Res 2013 Oct 15;73(20):6264-76. Epub 2013 Aug 15.

Authors' Affiliations: Departments of Pathology and Dermatology, New York University School of Medicine; Interdisciplinary Melanoma Cooperative Group, New York University Cancer Institute, New York University Langone Medical Center; Departments of Structural and Chemical Biology and Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; Instituto de Salud Carlos III, Majadahonda, Madrid; and Laboratory of Translational Research in Childhood Cancer, Vall d'Hebrón Institut de Recerca (VHIR), Barcelona, Spain.

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October 2013

Development and characterization of a clinically relevant mouse model of melanoma brain metastasis.

Pigment Cell Melanoma Res 2013 Sep 4;26(5):743-5. Epub 2013 Jun 4.

The Bernard & Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Langone Medical Center (NYULMC), New York, NY, USA.

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September 2013

In vivo Modeling and Molecular Characterization: A Path Toward Targeted Therapy of Melanoma Brain Metastasis.

Front Oncol 2013 31;3:127. Epub 2013 May 31.

Interdisciplinary Melanoma Cooperative Group, NYU Cancer Institute, NYU Langone Medical Center , New York, NY , USA ; Department of Pathology, NYU School of Medicine , New York, NY , USA.

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June 2013

FBH1 protects melanocytes from transformation and is deregulated in melanomas.

Cell Cycle 2013 Apr 6;12(7):1128-32. Epub 2013 Mar 6.

Department of Pathology, NYU Cancer Institute, New York University School of Medicine, New York, NY, USA.

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April 2013

MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.

J Pathol 2012 Oct 18;228(2):204-15. Epub 2012 Apr 18.

Department of Pathology, Northwestern University School of Medicine, Chicago, IL 60611, USA.

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October 2012

MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy.

Carcinogenesis 2012 Oct 12;33(10):1823-32. Epub 2012 Jun 12.

Department of Pathology, NYU Langone Medical Center, New York, NY, USA.

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October 2012

Serum microRNAs as biomarkers for recurrence in melanoma.

J Transl Med 2012 Aug 2;10:155. Epub 2012 Aug 2.

Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine, New York, NY, USA.

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August 2012

miRNA-mediated GALNT modulation of invasion and immune suppression: A sweet deal for metastatic cells.

Oncoimmunology 2012 Aug;1(5):746-748

Department of Pathology; New York University School of Medicine; New York, NY USA.

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August 2012

Histology-specific microRNA alterations in melanoma.

J Invest Dermatol 2012 Jul 3;132(7):1860-8. Epub 2012 May 3.

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York, USA.

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July 2012

Challenging the current paradigm of melanoma progression: brain metastasis as isolated first visceral site.

Neuro Oncol 2012 Jul 3;14(7):849-58. Epub 2012 May 3.

Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA.

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July 2012

MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells.

Hum Mol Genet 2012 May 10;21(10):2157-65. Epub 2012 Feb 10.

Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), E-28029 Madrid, Spain.

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May 2012

The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma.

PLoS One 2011 29;6(9):e25264. Epub 2011 Sep 29.

Department of Medicine, New York University School of Medicine, New York, New York, United States of America.

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March 2012

Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival.

Cancer 2011 Apr 8;117(8):1711-20. Epub 2010 Nov 8.

The New York University Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine and New York University Cancer Institute, New York, New York, USA.

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April 2011

Regulation of HMGA1 expression by microRNA-296 affects prostate cancer growth and invasion.

Clin Cancer Res 2011 Mar 7;17(6):1297-305. Epub 2010 Dec 7.

Department of Pathology, Northwestern University, Feinberg Medical School, Chicago, Illinois, USA.

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March 2011

Clinical relevance of SKP2 alterations in metastatic melanoma.

Pigment Cell Melanoma Res 2011 Feb 21;24(1):197-206. Epub 2010 Oct 21.

Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA.

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February 2011

HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes.

Cancer Res 2011 Jan 11;71(2):349-59. Epub 2011 Jan 11.

Key Laboratory for Experimental Teratology of the Ministry of Education, Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, PR China.

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January 2011

Profiling and functional analyses of microRNAs and their target gene products in human uterine leiomyomas.

PLoS One 2010 Aug 24;5(8):e12362. Epub 2010 Aug 24.

Department of Pathology, School of Medicine, New York University, New York, New York, United States of America.

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August 2010

Melanoma MicroRNA signature predicts post-recurrence survival.

Clin Cancer Res 2010 Mar 23;16(5):1577-86. Epub 2010 Feb 23.

Department of Pathology, New York University School of Medicine, New York, New York, USA.

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March 2010

Viral oncolysis that targets Raf-1 signaling control of nuclear transport.

J Virol 2010 Feb 25;84(4):2090-9. Epub 2009 Nov 25.

Centro de Biología Molecular "Severo Ochoa", Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.

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February 2010

Let-7 repression leads to HMGA2 overexpression in uterine leiomyosarcoma.

J Cell Mol Med 2009 Sep 13;13(9B):3898-905. Epub 2008 Oct 13.

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

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September 2009

Expression of insulin-like growth factors (IGFs) and IGF signaling: molecular complexity in uterine leiomyomas.

Fertil Steril 2009 Jun 25;91(6):2664-75. Epub 2008 Apr 25.

Department of Pathology, New York University School of Medicine, New York, New York 10016, USA.

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June 2009

Cancer. Aneuploidy advantages?

Authors:
Eva Hernando

Science 2008 Oct;322(5902):692-3

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.

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October 2008

A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.

Am J Pathol 2008 Apr 29;172(4):1069-80. Epub 2008 Feb 29.

Department of Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University, 1130 St. Nicholas Avenue, New York, NY 10032, USA.

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April 2008

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.

Nature 2008 Mar;452(7185):365-9

Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, MSB 599, New York, New York 10016, USA.

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March 2008

Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations.

Proc Natl Acad Sci U S A 2007 Oct 5;104(42):16633-8. Epub 2007 Oct 5.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA.

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October 2007

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas.

Nat Med 2007 Jun 13;13(6):748-53. Epub 2007 May 13.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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June 2007

Role of the chromobox protein CBX7 in lymphomagenesis.

Proc Natl Acad Sci U S A 2007 Mar 20;104(13):5389-94. Epub 2007 Mar 20.

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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March 2007

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.

Nature 2007 Feb 24;445(7128):656-60. Epub 2007 Jan 24.

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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February 2007

Mad2 overexpression promotes aneuploidy and tumorigenesis in mice.

Cancer Cell 2007 Jan 28;11(1):9-23. Epub 2006 Dec 28.

Cancer Biology and Genetics Program, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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January 2007

Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells.

Mol Cancer Ther 2006 Sep;5(9):2172-81

Instituto de Biología Molecular y Celular, Edificio Torregaitán, Universidad Miguel Hernández, 03202 Elche, Spain.

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September 2006

p73beta-Mediated apoptosis requires p57kip2 induction and IEX-1 inhibition.

Cancer Res 2005 Mar;65(6):2186-92

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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March 2005

Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells.

Proc Natl Acad Sci U S A 2004 Mar 15;101(13):4459-64. Epub 2004 Mar 15.

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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March 2004

Tumor promotion by Mdm2 splice variants unable to bind p53.

Cancer Res 2003 Sep;63(18):5703-6

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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September 2003

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo.

Nat Genet 2003 Mar 3;33(3):396-400. Epub 2003 Feb 3.

Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Cold Spring Harbor, New York 11724, USA.

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March 2003

Separation of live cells in different phases of the cell cycle for gene expression analysis.

Cytometry 2002 Dec;49(4):170-5

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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December 2002