Eva Brand

Eva Brand

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Eva Brand

Publications by authors named "Eva Brand"

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Soluble adenylyl cyclase (sAC) regulates calcium signaling in the vascular endothelium.

FASEB J 2019 Oct 4:fj201900724R. Epub 2019 Oct 4.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1096/fj.201900724RDOI Listing
October 2019

Neutralising anti-drug antibodies in Fabry disease can inhibit endothelial enzyme uptake and activity.

J Inherit Metab Dis 2019 Oct 6. Epub 2019 Oct 6.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/jimd.12176DOI Listing
October 2019

Circulating microRNAs in Fabry Disease.

Sci Rep 2019 Oct 24;9(1):15277. Epub 2019 Oct 24.

Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1038/s41598-019-51805-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813291PMC
October 2019

Mutation-specific Fabry disease patient-derived cell model to evaluate the amenability to chaperone therapy.

J Med Genet 2019 Aug 22;56(8):548-556. Epub 2019 Apr 22.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1136/jmedgenet-2019-106005DOI Listing
August 2019

Effects of high-intensity interval training on microvascular glycocalyx and associated microRNAs.

Am J Physiol Heart Circ Physiol 2019 Jun 12;316(6):H1538-H1551. Epub 2019 Apr 12.

Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1152/ajpheart.00751.2018DOI Listing
June 2019

Importance of the cultivation history for the response of Escherichia coli to oscillations in scale-down experiments.

Bioprocess Biosyst Eng 2018 Sep 28;41(9):1305-1313. Epub 2018 May 28.

Chair of Bioprocess Engineering, Department of Biotechnology, Technische Universität Berlin, Ackerstraße 71-76, ACK24, 13355, Berlin, Germany.

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http://dx.doi.org/10.1007/s00449-018-1958-4DOI Listing
September 2018

Effects of Enzyme Replacement Therapy and Antidrug Antibodies in Patients with Fabry Disease.

J Am Soc Nephrol 2018 09 9;29(9):2265-2278. Epub 2018 Aug 9.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1681/ASN.2018030329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115664PMC
September 2018

Neutralizing anti-drug antibodies in Fabry disease have no obvious clinical impact?

Orphanet J Rare Dis 2018 09 29;13(1):171. Epub 2018 Sep 29.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Albert-Schweitzer-Campus 1, D-48149, Muenster, Germany.

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https://ojrd.biomedcentral.com/articles/10.1186/s13023-018-0
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http://dx.doi.org/10.1186/s13023-018-0916-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162957PMC
September 2018

Fabry disease under enzyme replacement therapy-new insights in efficacy of different dosages.

Nephrol Dial Transplant 2018 08;33(8):1362-1372

Department of Internal Medicine I, Divisions of Cardiology and Nephrology, Comprehensive Heart Failure Center, Fabry Center for Interdisciplinary Therapy (FAZIT), University Hospital and University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfx319DOI Listing
August 2018

[Cystinosis : Diagnosis, cystine-depleting therapy, and transition].

Internist (Berl) 2018 08;59(8):861-867

Klinik für Pädiatrische Nieren‑, Leber- und Stoffwechselerkrankungen, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

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http://dx.doi.org/10.1007/s00108-018-0416-3DOI Listing
August 2018

Characterization of drug-neutralizing antibodies in patients with Fabry disease during infusion.

J Allergy Clin Immunol 2018 06 5;141(6):2289-2292.e7. Epub 2018 Feb 5.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.12.1001DOI Listing
June 2018

Promoter methylation inhibits expression of tumor suppressor KIBRA in human clear cell renal cell carcinoma.

Clin Epigenetics 2017 6;9:109. Epub 2017 Oct 6.

Internal Medicine D, Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany.

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http://dx.doi.org/10.1186/s13148-017-0415-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639574PMC
May 2018

ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA.

Sci Rep 2018 03 9;8(1):4230. Epub 2018 Mar 9.

University Hospital Muenster, Internal Medicine D, Nephrology, Hypertension and Rheumatology, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.

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http://dx.doi.org/10.1038/s41598-018-22600-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844865PMC
March 2018

Renal function predicts long-term outcome on enzyme replacement therapy in patients with Fabry disease.

Nephrol Dial Transplant 2017 Dec;32(12):2090-2097

Department ofNephrology, Hypertension, and Rheumatology, Internal Medicine D, University Hospital Muenster, Albert-Schweitzer-Campus 1, D-48149 Muenster, Germany.

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http://dx.doi.org/10.1093/ndt/gfw334DOI Listing
December 2017

Salt-induced Na/K-ATPase-α/β expression involves soluble adenylyl cyclase in endothelial cells.

Pflugers Arch 2017 10 26;469(10):1401-1412. Epub 2017 May 26.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.

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http://dx.doi.org/10.1007/s00424-017-1999-6DOI Listing
October 2017

Dose-Response of High-Intensity Training (HIT) on Atheroprotective miRNA-126 Levels.

Front Physiol 2017 30;8:349. Epub 2017 May 30.

Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital MuensterMuenster, Germany.

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http://dx.doi.org/10.3389/fphys.2017.00349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447767PMC
May 2017

Elevated copeptin is a prognostic factor for mortality even in patients with renal dysfunction.

Int J Cardiol 2016 Oct 5;221:327-32. Epub 2016 Jul 5.

Division of Vascular Medicine, Department of Cardiovascular Medicine, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2016.07.058DOI Listing
October 2016

Fabry in the older patient: Clinical consequences and possibilities for treatment.

Mol Genet Metab 2016 08 14;118(4):319-25. Epub 2016 May 14.

Lysosomal Storage Disorders Unit, Department of Haematology, Royal Free London NHS Foundation Trust and University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2016.05.009DOI Listing
August 2016

Alpha-Galactosidase A p.A143T, a non-Fabry disease-causing variant.

Orphanet J Rare Dis 2016 05 4;11(1):54. Epub 2016 May 4.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Albert-Schweitzer-Campus 1, D-48149, Muenster, Germany.

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http://dx.doi.org/10.1186/s13023-016-0441-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855861PMC
May 2016

Serum-Mediated Inhibition of Enzyme Replacement Therapy in Fabry Disease.

J Am Soc Nephrol 2016 Jan 30;27(1):256-64. Epub 2015 Apr 30.

Department of Nephrology, Hypertension, and Rheumatology, Internal Medicine D, University Hospital Muenster, Muenster, Germany;

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http://dx.doi.org/10.1681/ASN.2014121226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696578PMC
January 2016

Differential response to endothelial epithelial sodium channel inhibition ex vivo correlates with arterial stiffness in humans.

J Hypertens 2015 Dec;33(12):2455-62

aUniversity Hospital Muenster, Internal Medicine D, Nephrology, Hypertension and Rheumatology bUniversity of Muenster, Institute of Physiology II cUniversity Hospital Muenster, Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease dUniversity Hospital Muenster, Department of Vascular and Endovascular Surgery eUniversity of Muenster, Institute of Anatomy and Molecular Neurobiology, Muenster, Germany *Malte Lenders and Verena Hofschröer contributed equally to the writing of this article. †Kristina Kusche-Vihrog and Eva Brand contributed equally to the writing of this article.

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http://dx.doi.org/10.1097/HJH.0000000000000736DOI Listing
December 2015

Soluble Flt-1 links microvascular disease with heart failure in CKD.

Basic Res Cardiol 2015 May 21;110(3):30. Epub 2015 Apr 21.

Department of Internal Medicine D, University Hospital Münster, Albert Schweitzer Campus 1, Gebäude A1, 48149, Münster, Germany,

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http://dx.doi.org/10.1007/s00395-015-0487-4DOI Listing
May 2015

Salt controls endothelial and vascular phenotype.

Pflugers Arch 2015 Mar 26;467(3):499-512. Epub 2014 Nov 26.

Institute of Physiology II, University of Muenster, Robert-Koch-Str. 27b, 48149, Muenster, Germany,

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http://dx.doi.org/10.1007/s00424-014-1657-1DOI Listing
March 2015

Thromboembolic events in Fabry disease and the impact of factor V Leiden.

Neurology 2015 Mar 6;84(10):1009-16. Epub 2015 Feb 6.

From Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology (M.L., M.S., E.B.), Department of Neurology (T.D.), Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease (B.S., S.-M.B.), Internal Medicine A, Department of Hematology and Oncology (R.M.), Institute of Epidemiology and Social Medicine (H.-W.H.), University Hospital Muenster; and Department of Pediatric and Adolescent Medicine (N.K., M.B.), Villa Metabolica, University Medical Center of the Johannes Gutenberg University, University of Mainz, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000001333DOI Listing
March 2015

Aldosterone signaling and soluble adenylyl cyclase-a nexus for the kidney and vascular endothelium.

Biochim Biophys Acta 2014 Dec 5;1842(12 Pt B):2601-9. Epub 2014 Jun 5.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.05.036DOI Listing
December 2014

Identification of genetic markers for treatment success in heart failure patients: insight from cardiac resynchronization therapy.

Circ Cardiovasc Genet 2014 Dec 10;7(6):760-70. Epub 2014 Sep 10.

From the Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease (B.S., S.-M.B.) and Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology (B.S., M. Lenders, E.B.), University Hospital Münster, Münster, Germany; Cardiothoracic and Vascular Department, CNR Institute of Clinical Physiology, Niguarda Ca' Granda Hospital, Milan, Italy (R.D.M., J.C., M.P., O.P.); University of Ioannina, Department of Biomedical Research, Ioannina University Campus (D.G.); Neuron Energy Solutions G.P., Science & Technology Park of Epirus, Ioannina, Greece (T.C.); Department of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia (M. Landolina, A.S.); Department of Cardiology, Humanitas Research Hospital IRCCS, Rozzano-Milan (M.G., P.G.); and Cardiothoracic and Vascular Department, Niguarda Ca' Granda Hospital, Milan, Italy (M.B., M. Lunati).

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http://dx.doi.org/10.1161/CIRCGENETICS.113.000384DOI Listing
December 2014

Cryptogenic stroke and small fiber neuropathy of unknown etiology in patients with alpha-galactosidase A -10T genotype.

Orphanet J Rare Dis 2014 Nov 26;9:178. Epub 2014 Nov 26.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.

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http://dx.doi.org/10.1186/s13023-014-0178-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255940PMC
November 2014

Soluble adenylyl cyclase in vascular endothelium: gene expression control of epithelial sodium channel-α, Na+/K+-ATPase-α/β, and mineralocorticoid receptor.

Hypertension 2014 Apr 13;63(4):753-61. Epub 2014 Jan 13.

University Hospital Muenster, Internal Medicine D, Department of Nephrology, Hypertension, and Rheumatology, Albert-Schweitzer-Campus 1, D-48149 Muenster, Germany.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02061DOI Listing
April 2014

Tissue-specific differences in the regulation of KIBRA gene expression involve transcription factor TCF7L2 and a complex alternative promoter system.

J Mol Med (Berl) 2014 Feb 27;92(2):185-96. Epub 2013 Sep 27.

Internal Medicine D, Nephrology, Hypertension and Rheumatology, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00109-013-1089-yDOI Listing
February 2014

Enzyme-based glucose delivery: a possible tool for biosorbent preparation for heavy metal removal from polluted environments.

Bioprocess Biosyst Eng 2013 Nov 3;36(11):1601-11. Epub 2013 Mar 3.

Faculty of Food Science and Engineering, "Dunarea de Jos" University, 111 Domneasca Street, 800201, Galaţi, Romania,

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http://dx.doi.org/10.1007/s00449-013-0934-2DOI Listing
November 2013

Impact of peripheral arterial occlusive disease on the development of contrast medium-induced acute kidney injury.

Nephron Clin Pract 2012 21;122(1-2):38-43. Epub 2013 Mar 21.

Division of Angiology, Department of Cardiology and Angiology, University Hospital of Münster, Münster, Germany. f.lueders @ gmx.net

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http://dx.doi.org/10.1159/000346105DOI Listing
October 2013

Increased monocyte adhesion by endothelial expression of VCAM-1 missense variation in vitro.

Atherosclerosis 2013 Oct 31;230(2):185-90. Epub 2013 Jul 31.

University Hospital Münster, Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, Horstmarer Landweg 39, D-48149 Münster, Germany; University Hospital Münster, Internal Medicine D, Nephrology, Hypertension and Rheumatology, Münster, Germany.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.07.039DOI Listing
October 2013

The Coronary Artery Disease and Renal Failure (CAD-REF) registry: trial design, methods, and aims.

Am Heart J 2013 Sep 23;166(3):449-56. Epub 2013 Jul 23.

Department of Nephrology, Hypertension, and Rheumatology, University Hospital of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1016/j.ahj.2013.06.010DOI Listing
September 2013

Enhanced plasmid production in miniaturized high-cell-density cultures of Escherichia coli supported with perfluorinated oxygen carrier.

Bioprocess Biosyst Eng 2013 Aug 23;36(8):1079-86. Epub 2012 Nov 23.

Chair of Bioprocess Engineering, Department of Biotechnology, Technische Universität Berlin, Berlin, Germany.

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http://dx.doi.org/10.1007/s00449-012-0861-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722437PMC
August 2013

Multifocal white matter lesions associated with the D313Y mutation of the α-galactosidase A gene.

PLoS One 2013 5;8(2):e55565. Epub 2013 Feb 5.

Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055565PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564750PMC
August 2013

Interindividual transcriptional regulation of the human biglycan gene involves three common molecular haplotypes.

Arterioscler Thromb Vasc Biol 2013 Apr 7;33(4):871-80. Epub 2013 Feb 7.

Institute for Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Münster, Germany.

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http://dx.doi.org/10.1161/ATVBAHA.112.301073DOI Listing
April 2013

Association of left ventricular mass with the AGTR1 A1166C polymorphism.

Am J Hypertens 2012 Apr 12;25(4):472-8. Epub 2012 Jan 12.

Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Belgium.

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http://dx.doi.org/10.1038/ajh.2011.244DOI Listing
April 2012

Are retinal microvascular phenotypes associated with the 1675G/A polymorphism in the angiotensin II type-2 receptor gene?

Am J Hypertens 2011 Dec 18;24(12):1300-5. Epub 2011 Aug 18.

Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/ajh.2011.151DOI Listing
December 2011

Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor.

Am J Physiol Cell Physiol 2011 Oct 27;301(4):C780-91. Epub 2011 Jul 27.

Department of Surgery, University of California, San Francisco, 94143-0660, USA.

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http://dx.doi.org/10.1152/ajpcell.00096.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191565PMC
October 2011

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Authors:
Georg B Ehret Patricia B Munroe Kenneth M Rice Murielle Bochud Andrew D Johnson Daniel I Chasman Albert V Smith Martin D Tobin Germaine C Verwoert Shih-Jen Hwang Vasyl Pihur Peter Vollenweider Paul F O'Reilly Najaf Amin Jennifer L Bragg-Gresham Alexander Teumer Nicole L Glazer Lenore Launer Jing Hua Zhao Yurii Aulchenko Simon Heath Siim Sõber Afshin Parsa Jian'an Luan Pankaj Arora Abbas Dehghan Feng Zhang Gavin Lucas Andrew A Hicks Anne U Jackson John F Peden Toshiko Tanaka Sarah H Wild Igor Rudan Wilmar Igl Yuri Milaneschi Alex N Parker Cristiano Fava John C Chambers Ervin R Fox Meena Kumari Min Jin Go Pim van der Harst Wen Hong Linda Kao Marketa Sjögren D G Vinay Myriam Alexander Yasuharu Tabara Sue Shaw-Hawkins Peter H Whincup Yongmei Liu Gang Shi Johanna Kuusisto Bamidele Tayo Mark Seielstad Xueling Sim Khanh-Dung Hoang Nguyen Terho Lehtimäki Giuseppe Matullo Ying Wu Tom R Gaunt N Charlotte Onland-Moret Matthew N Cooper Carl G P Platou Elin Org Rebecca Hardy Santosh Dahgam Jutta Palmen Veronique Vitart Peter S Braund Tatiana Kuznetsova Cuno S P M Uiterwaal Adebowale Adeyemo Walter Palmas Harry Campbell Barbara Ludwig Maciej Tomaszewski Ioanna Tzoulaki Nicholette D Palmer Thor Aspelund Melissa Garcia Yen-Pei C Chang Jeffrey R O'Connell Nanette I Steinle Diederick E Grobbee Dan E Arking Sharon L Kardia Alanna C Morrison Dena Hernandez Samer Najjar Wendy L McArdle David Hadley Morris J Brown John M Connell Aroon D Hingorani Ian N M Day Debbie A Lawlor John P Beilby Robert W Lawrence Robert Clarke Jemma C Hopewell Halit Ongen Albert W Dreisbach Yali Li J Hunter Young Joshua C Bis Mika Kähönen Jorma Viikari Linda S Adair Nanette R Lee Ming-Huei Chen Matthias Olden Cristian Pattaro Judith A Hoffman Bolton Anna Köttgen Sven Bergmann Vincent Mooser Nish Chaturvedi Timothy M Frayling Muhammad Islam Tazeen H Jafar Jeanette Erdmann Smita R Kulkarni Stefan R Bornstein Jürgen Grässler Leif Groop Benjamin F Voight Johannes Kettunen Philip Howard Andrew Taylor Simonetta Guarrera Fulvio Ricceri Valur Emilsson Andrew Plump Inês Barroso Kay-Tee Khaw Alan B Weder Steven C Hunt Yan V Sun Richard N Bergman Francis S Collins Lori L Bonnycastle Laura J Scott Heather M Stringham Leena Peltonen Markus Perola Erkki Vartiainen Stefan-Martin Brand Jan A Staessen Thomas J Wang Paul R Burton Maria Soler Artigas Yanbin Dong Harold Snieder Xiaoling Wang Haidong Zhu Kurt K Lohman Megan E Rudock Susan R Heckbert Nicholas L Smith Kerri L Wiggins Ayo Doumatey Daniel Shriner Gudrun Veldre Margus Viigimaa Sanjay Kinra Dorairaj Prabhakaran Vikal Tripathy Carl D Langefeld Annika Rosengren Dag S Thelle Anna Maria Corsi Andrew Singleton Terrence Forrester Gina Hilton Colin A McKenzie Tunde Salako Naoharu Iwai Yoshikuni Kita Toshio Ogihara Takayoshi Ohkubo Tomonori Okamura Hirotsugu Ueshima Satoshi Umemura Susana Eyheramendy Thomas Meitinger H-Erich Wichmann Yoon Shin Cho Hyung-Lae Kim Jong-Young Lee James Scott Joban S Sehmi Weihua Zhang Bo Hedblad Peter Nilsson George Davey Smith Andrew Wong Narisu Narisu Alena Stančáková Leslie J Raffel Jie Yao Sekar Kathiresan Christopher J O'Donnell Stephen M Schwartz M Arfan Ikram W T Longstreth Thomas H Mosley Sudha Seshadri Nick R G Shrine Louise V Wain Mario A Morken Amy J Swift Jaana Laitinen Inga Prokopenko Paavo Zitting Jackie A Cooper Steve E Humphries John Danesh Asif Rasheed Anuj Goel Anders Hamsten Hugh Watkins Stephan J L Bakker Wiek H van Gilst Charles S Janipalli K Radha Mani Chittaranjan S Yajnik Albert Hofman Francesco U S Mattace-Raso Ben A Oostra Ayse Demirkan Aaron Isaacs Fernando Rivadeneira Edward G Lakatta Marco Orru Angelo Scuteri Mika Ala-Korpela Antti J Kangas Leo-Pekka Lyytikäinen Pasi Soininen Taru Tukiainen Peter Würtz Rick Twee-Hee Ong Marcus Dörr Heyo K Kroemer Uwe Völker Henry Völzke Pilar Galan Serge Hercberg Mark Lathrop Diana Zelenika Panos Deloukas Massimo Mangino Tim D Spector Guangju Zhai James F Meschia Michael A Nalls Pankaj Sharma Janos Terzic M V Kranthi Kumar Matthew Denniff Ewa Zukowska-Szczechowska Lynne E Wagenknecht F Gerald R Fowkes Fadi J Charchar Peter E H Schwarz Caroline Hayward Xiuqing Guo Charles Rotimi Michiel L Bots Eva Brand Nilesh J Samani Ozren Polasek Philippa J Talmud Fredrik Nyberg Diana Kuh Maris Laan Kristian Hveem Lyle J Palmer Yvonne T van der Schouw Juan P Casas Karen L Mohlke Paolo Vineis Olli Raitakari Santhi K Ganesh Tien Y Wong E Shyong Tai Richard S Cooper Markku Laakso Dabeeru C Rao Tamara B Harris Richard W Morris Anna F Dominiczak Mika Kivimaki Michael G Marmot Tetsuro Miki Danish Saleheen Giriraj R Chandak Josef Coresh Gerjan Navis Veikko Salomaa Bok-Ghee Han Xiaofeng Zhu Jaspal S Kooner Olle Melander Paul M Ridker Stefania Bandinelli Ulf B Gyllensten Alan F Wright James F Wilson Luigi Ferrucci Martin Farrall Jaakko Tuomilehto Peter P Pramstaller Roberto Elosua Nicole Soranzo Eric J G Sijbrands David Altshuler Ruth J F Loos Alan R Shuldiner Christian Gieger Pierre Meneton Andre G Uitterlinden Nicholas J Wareham Vilmundur Gudnason Jerome I Rotter Rainer Rettig Manuela Uda David P Strachan Jacqueline C M Witteman Anna-Liisa Hartikainen Jacques S Beckmann Eric Boerwinkle Ramachandran S Vasan Michael Boehnke Martin G Larson Marjo-Riitta Järvelin Bruce M Psaty Gonçalo R Abecasis Aravinda Chakravarti Paul Elliott Cornelia M van Duijn Christopher Newton-Cheh Daniel Levy Mark J Caulfield Toby Johnson

C-reactive protein makes human endothelium stiff and tight.

Hypertension 2011 Feb 13;57(2):231-7. Epub 2010 Dec 13.

Institute of Physiology II, Muenster, Germany.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.163444DOI Listing
February 2011

The soluble VEGF receptor sFlt1 contributes to endothelial dysfunction in CKD.

J Am Soc Nephrol 2009 Oct 16;20(10):2235-45. Epub 2009 Jul 16.

Department of Internal Medicine D, University Clinics Münster, Münster, Germany.

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http://dx.doi.org/10.1681/ASN.2009010061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754110PMC
October 2009

Identification and functional analyses of molecular haplotypes of the human osteoprotegerin gene promoter.

Arterioscler Thromb Vasc Biol 2009 Oct 6;29(10):1638-43. Epub 2009 Aug 6.

Leibniz-Institute for Arteriosclerosis Research, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1161/ATVBAHA.109.193532DOI Listing
October 2009

Osteopontin gene variation and cardio/cerebrovascular disease phenotypes.

Atherosclerosis 2009 Sep 21;206(1):209-15. Epub 2009 Feb 21.

Leibniz-Institute for Arteriosclerosis Research, Department of Molecular Genetics of Cardiovascular Disease, University of Muenster, Domagkstrasse 3, Muenster, Germany.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.02.015DOI Listing
September 2009

Molecular genetic analysis of a human insulin-like growth factor 1 promoter P1 variation.

FASEB J 2009 May 22;23(5):1303-13. Epub 2008 Dec 22.

Department of Molecular Genetics of Cardiovascular Disease, Leibniz-Institute for Arteriosclerosis Research, University of Münster, Domagkstrasse 3, 48149 Münster, Germany.

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http://dx.doi.org/10.1096/fj.08-116863DOI Listing
May 2009

Dilemmas in the management of atrial fibrillation in chronic kidney disease.

J Am Soc Nephrol 2009 Apr 17;20(4):705-11. Epub 2008 Dec 17.

Department of Cardiology and Angiology, Medizinische Klinik und Poliklinik C, University Hospital of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1681/ASN.2007111207DOI Listing
April 2009

Left ventricular structure in relation to the human SAH gene in the European Project on Genes in Hypertension.

Hypertens Res 2009 Feb 16;32(2):145-51. Epub 2009 Jan 16.

Studies Coordinating Centre, Division of Hypertension and Cardiovascular Research, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/hr.2008.30DOI Listing
February 2009

Characterization and functional analyses of the human G protein-coupled receptor kinase 4 gene promoter.

Hypertension 2008 Oct 18;52(4):737-46. Epub 2008 Aug 18.

University Hospital Muenster, Department of Internal Medicine D, Muenster, Germany.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.108.114512DOI Listing
October 2008

Functional and structural profiling of the human thrombopoietin gene promoter.

J Biol Chem 2008 Sep 9;283(36):24382-91. Epub 2008 Jul 9.

Leibniz-Institute for Arteriosclerosis Research, Department of Molecular Genetics of Cardiovascular Disease, University of Münster, Münster D-48149, Germany.

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http://dx.doi.org/10.1074/jbc.M802198200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259845PMC
September 2008

Neutrophil elastase gene variation and coronary heart disease.

Pharmacogenet Genomics 2007 Aug;17(8):629-37

Department of Molecular Genetics of Cardiovascular Disease, Leibniz-Institute for Arteriosclerosis Research, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1097/FPC.0b013e328042bb46DOI Listing
August 2007

OASIS-HT: design of a pharmacogenomic dose-finding study.

Pharmacogenomics 2005 Oct;6(7):755-75

Department of Molecular and Cardiovascular Research, Hypertension and Cardiovascular Rehabilitation Unit, Study Coordinating Centre, University of Leuven, Belgium.

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http://dx.doi.org/10.2217/14622416.6.7.755DOI Listing
October 2005

Alcohol intake modulates the genetic association between HDL cholesterol and the PPARgamma2 Pro12Ala polymorphism.

J Lipid Res 2005 May 16;46(5):913-9. Epub 2005 Feb 16.

Leibniz Institute for Arteriosclerosis Research, Department of Molecular Genetics of Cardiovascular Disease, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1194/jlr.M400405-JLR200DOI Listing
May 2005

Left ventricular mass in relation to genetic variation in angiotensin II receptors, renin system genes, and sodium excretion.

Circulation 2004 Oct 18;110(17):2644-50. Epub 2004 Oct 18.

Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1161/01.CIR.0000145541.63406.BADOI Listing
October 2004

Genetic variation in CYP11B2 and AT1R influences heart rate variability conditional on sodium excretion.

Hypertension 2004 Aug 6;44(2):156-62. Epub 2004 Jul 6.

Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Belgium.

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http://dx.doi.org/10.1161/01.HYP.0000135846.91124.a5DOI Listing
August 2004

Angiotensinogen promoter haplotypes are associated with blood pressure in untreated hypertensives.

J Hypertens 2004 Jul;22(7):1289-97

Institute for Arteriosclerosis Research, Department of Molecular Genetics of Cardiovascular Disease, University of Muenster, Germany.

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http://dx.doi.org/10.1097/01.hjh.0000125429.28861.58DOI Listing
July 2004

Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio.

J Mol Med (Berl) 2003 May 28;81(5):327-32. Epub 2003 Mar 28.

Department of Clinical Pharmacology, Benjamin Franklin Medical Center, Freie Universität Berlin, Hindenburgdamm 30, 12200 Berlin, Germany.

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http://dx.doi.org/10.1007/s00109-003-0431-1DOI Listing
May 2003

[Pharmacogenetics and pharmacogenomics. Searching for individual antihypertensive therapy concepts].

Authors:
Eva Brand

MMW Fortschr Med 2003 May;145(19):43-4

Freie Universität Berlin, Klinikum Benjamin Franklin.

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May 2003

An epidemiological study of blood pressure and metabolic phenotypes in relation to the Gbeta3 C825T polymorphism.

J Hypertens 2003 Apr;21(4):729-37

Department of Endocrinology and Nephrology, Benjamin Franklin Medical Centre, Freie Universität Berlin, Germany.

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http://dx.doi.org/10.1097/00004872-200304000-00016DOI Listing
April 2003

Differential binding of transcription factor E2F-2 to the endothelin-converting enzyme-1b promoter affects blood pressure regulation.

Hum Mol Genet 2003 Feb;12(4):423-33

Institute of Clinical Pharmacology and Toxicology, Department of Clinical Pharmacology, Benjamin Franklin Medical Center, Freie Universität Berlin, Berlin, Germany.

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http://dx.doi.org/10.1093/hmg/ddg040DOI Listing
February 2003

Peroxisome proliferator-activated receptor-gamma2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study.

Diabetes 2002 Aug;51(8):2653-7

Department of Clinical Pharmacology, Division of Endocrinology and Nephrology, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Berlin, Germany.

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http://dx.doi.org/10.2337/diabetes.51.8.2653DOI Listing
August 2002

Carotid and femoral intima-media thickness in relation to three candidate genes in a Caucasian population.

J Hypertens 2002 Aug;20(8):1551-61

Cardiovascular Research Institute Maastricht, Capaciteitsgroep Farmakologie en Toxicologie, Universiteit Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1097/00004872-200208000-00018DOI Listing
August 2002