Publications by authors named "Eunice L Kwak"

88Publications

Phase II Study of Proton-Based Stereotactic Body Radiation Therapy for Liver Metastases: Importance of Tumor Genotype.

J Natl Cancer Inst 2017 09;109(9)

Department of Radiation Oncology, Department of Pathology, Division of Biostatistics, Department of Medicine, Division of Medical Oncology, Department of Medicine, Department of Radiology, and Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.

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September 2017

Case 35-2016. A 62-Year-Old Man with Dysphagia.

N Engl J Med 2016 11;375(20):1983-1991

From the Departments of Medicine (E.L.K., D.G.F.), Radiation Oncology (T.S.H.), Radiology (A.K.), and Pathology (J.K.L.), Massachusetts General Hospital, and the Departments of Medicine (E.L.K., D.G.F.), Radiation Oncology (T.S.H.), Radiology (A.K.), and Pathology (J.K.L.), Harvard Medical School - both in Boston.

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November 2016

What's the Best Way to Treat GE Junction Tumors? Approach Like Gastric Cancer.

Ann Surg Oncol 2016 11 26;23(12):3780-3785. Epub 2016 Jul 26.

Harvard Medical School, Boston, MA, USA.

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November 2016

The impact of neoadjuvant therapy for gastroesophageal adenocarcinoma on postoperative morbidity and mortality.

J Surg Oncol 2016 Apr 21;113(5):560-4. Epub 2016 Jan 21.

Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts.

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April 2016

Multi-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.

J Clin Oncol 2016 Feb 14;34(5):460-8. Epub 2015 Dec 14.

Theodore S. Hong, Jennifer Y. Wo, Beow Y. Yeap, Erin I. McDonnell, Lawrence S. Blaszkowsky, Eunice L. Kwak, Jill N. Allen, Jeffrey W. Clark, Lipika Goyal, Janet E. Murphy, John A. Wolfgang, Lorraine C. Drapek, Ronald S. Arellano, John T. Mullen, Sam S. Yoon, Kenneth K. Tanabe, Cristina R. Ferrone, David P. Ryan, Thomas F. DeLaney, and Andrew X. Zhu, Massachusetts General Hospital, Harvard Medical School; Harvey J. Mamon, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; Edgar Ben-Josef, University of Pennsylvania Hospital, Philadelphia, PA; and Milind M. Javle and Christopher H. Crane, University of Texas MD Anderson Cancer Center, Houston, TX.

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February 2016

Familial Gastric Cancers.

Oncologist 2015 Dec 30;20(12):1365-77. Epub 2015 Sep 30.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

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December 2015

Adjuvant Therapy Completion Rates in Patients with Gastric Cancer Undergoing Perioperative Chemotherapy Versus a Surgery-First Approach.

J Gastrointest Surg 2016 Jan 22;20(1):172-9; discussion 179. Epub 2015 Sep 22.

Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Yawkey 7B, Boston, MA, 02114, USA.

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January 2016

Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.

J Clin Oncol 2015 Dec 21;33(34):4023-31. Epub 2015 Sep 21.

Ryan B. Corcoran, Eunice L. Kwak, and David P. Ryan, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA; Chloe E. Atreya, Adil Daud, and Alan P. Venook, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco; Omid Hamid, Angeles Clinic and Research Institute, Los Angeles, CA; Gerald S. Falchook, Sarah Cannon Research Institute at HealthONE, Denver; Wells A. Messersmith, University of Colorado Cancer Center and University of Colorado, Aurora, CO; Johanna C. Bendell, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Razelle Kurzrock and Scott Kopetz, University of Texas, MD Anderson Cancer Center, Houston, TX; Mariaelena Pierobon, Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA; Peng Sun, Elizabeth Cunningham, Shonda Little, Keith Orford, Monica Motwani, and Yuchen Bai, GlaxoSmithKline, Philadelphia, PA; and Kiran Patel, Incyte, Wilmington, DE.

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December 2015

Predictors of Lymph Node Metastasis in Western Early Gastric Cancer.

J Gastrointest Surg 2016 Mar 18;20(3):531-8. Epub 2015 Sep 18.

Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Yawkey 7B, Boston, MA, 02114, USA.

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March 2016

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.

N Engl J Med 2015 Jul;373(5):428-37

From Memorial Sloan Kettering Cancer Center (W.D.T., J.H.H.) and Weill Cornell Medical College (W.D.T.) - both in New York; University of California, Los Angeles, Medical Center, Los Angeles (Z.A.W., B.C., A.S.S.), Plexxikon, Berkeley (P.N.I., C.Z., J.Z., G.H., Y.Z., E.A.B., G.V., L.S., P.S., H.N., M.J.K., A.M., G.T., R.S., C.G., B.L.W., P.H., K.N., H.H.H., P.S.L., S.T.-S., G.B.), and Stanford University School of Medicine, Stanford (M.R.) - all in California; Evergreen Hematology and Oncology, Spokane, WA (S.P.A.); University of Pennsylvania School of Medicine, Philadelphia (A.P.S.); Rocky Mountain Cancer Centers, Denver (A.L.C.); Dana-Farber Cancer Institute (G.I.S., A.J.W.) and Massachusetts General Hospital (E.L.K.) - both in Boston; Vanderbilt University Medical Center, Nashville (V.L.K., I.P.); Virginia G. Piper Cancer Center at Scottsdale Healthcare-Translational Genomics Research Institute (TGen), Scottsdale, AZ (D.D.V.H., G.J.W., R.K.R.); and Spire Sciences, Boca Raton, FL (C.P.).

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July 2015

Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease.

Cancer Chemother Pharmacol 2015 Apr 28;75(4):701-9. Epub 2015 Jan 28.

Division of Hematology/Oncology, Vanderbilt-Ingram Cancer Center, 2220 Pierce Avenue, 777 Preston Research Building, Nashville, TN, 37232-6307, USA,

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April 2015

Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.

Int J Cancer 2015 Apr 29;136(8):1967-75. Epub 2014 Sep 29.

Division of Medical Oncology, University of Colorado Denver and University of Colorado Cancer Center, Aurora, CO; Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Republic of Korea.

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April 2015

Adjuvant therapy for gastric cancers: more answers or more questions?

Ann Surg Oncol 2014 Oct 20;21(11):3367-8. Epub 2014 May 20.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,

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October 2014

The Impact of Positive Margins on Outcome Among Patients With Gastric Cancer Treated With Radiation.

Am J Clin Oncol 2016 06;39(3):243-7

Departments of *Radiation Oncology ∥Medical Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute Departments of †Radiation Oncology ‡Medical Oncology §Surgical Oncology, Massachusetts General Hospital, Boston, MA.

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June 2016

Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors.

J Clin Oncol 2014 Jan 9;32(2):68-75. Epub 2013 Dec 9.

Leena Gandhi, Sara M. Tolaney, James M. Cleary, and Geoffrey I. Shapiro, Dana-Farber Cancer Institute; Eunice L. Kwak, Massachusetts General Hospital; Shuchi S. Pandya, Beth Israel Deaconess Medical Center, Boston; Anna Berkenblit and Mizue Krygowski, Aveo Pharmaceuticals; Revathi Ananthakrishnan and Kathleen W. Turnbull, Inventiv Health, Cambridge, MA; Rastislav Bahleda, Antoine Hollebecque, and Jean-Charles Soria, Insitut Gussav Roussy, Villejuif, France; Richat Abbas and Yali Liang, Pfizer, Collegeville, PA.

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January 2014

Phase I safety, pharmacokinetic, and pharmacodynamic study of SAR245408 (XL147), an oral pan-class I PI3K inhibitor, in patients with advanced solid tumors.

Clin Cancer Res 2014 Jan 28;20(1):233-45. Epub 2013 Oct 28.

Authors' Affiliations: Dana-Farber Cancer Institute; Massachusetts General Hospital; Beth Israel Deaconess Medical Center, Boston, Massachusetts; Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain; Mary Crowley Cancer Research Centers, Dallas, Texas; Exelixis Inc., South San Francisco, California; and Sanofi, Cambridge, Massachusetts, and Vitry-sur-Seine, France.

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January 2014

Noncurative gastrectomy for gastric adenocarcinoma should only be performed in highly selected patients.

Ann Surg Oncol 2013 Oct 14;20(11):3512-8. Epub 2013 Jun 14.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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October 2013

Targeted inhibition in tumors with ALK dependency.

Lung Cancer (Auckl) 2013 9;4:1-8. Epub 2013 Jan 9.

Massachusetts General Hospital Cancer Center, Boston, MA, USA.

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January 2013

Targeted therapies with chemoradiation in esophageal cancer: development and future directions.

Semin Radiat Oncol 2013 Jan;23(1):31-7

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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January 2013

A matter of timing: is there a role for radiation in locally advanced pancreatic cancer, and if so, when?

Am Soc Clin Oncol Educ Book 2012 :238-42

From the Departments of Radiation Oncology and Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

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April 2016

Isolation of rare circulating tumour cells in cancer patients by microchip technology.

Nature 2007 Dec;450(7173):1235-9

Surgical Services and BioMEMS Resource Center, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospital for Children, Boston, Massachusetts 02114, USA.

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December 2007

Targeted agents: the rules of combination.

Clin Cancer Res 2007 Sep;13(18 Pt 1):5232-7

Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114, USA.

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September 2007

Hereditary colorectal cancer syndromes: an overview.

Clin Colorectal Cancer 2007 Jan;6(5):340-4

Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA.

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January 2007

Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant.

Cancer Res 2006 Feb;66(4):1923-8

Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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February 2006

Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer.

Gynecol Oncol 2005 Jul;98(1):124-8

Massachusetts General Hospital Cancer Center and Harvard Medical School, Building 149, CNY-7, 13th Street, Charlestown, MA 02129, USA.

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July 2005