Publications by authors named "Eui Man Jeong"

35Publications

Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding protein-protein interactions of the fused protein.

Authors:
Hyo-Jun Kim Jin-Haeng Lee Ki Baek Lee Ji-Woong Shin Mee-Ae Kwon Soojin Lee Eui Man Jeong Sung-Yup Cho In-Gyu Kim

Exp Mol Med 2021 Jan 13. Epub 2021 Jan 13.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea.

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January 2021

Targeting antioxidant enzymes enhances the therapeutic efficacy of the BCL-X inhibitor ABT-263 in KRAS-mutant colorectal cancers.

Authors:
Yumi Oh Hae Rim Jung Seoyeon Min Jinjoo Kang Dongjun Jang Seungjae Shin Jiwon Kim Sang Eun Lee Chang Ohk Sung Won-Suk Lee Charles Lee Eui Man Jeong Sung-Yup Cho

Cancer Lett 2021 Jan 15;497:123-136. Epub 2020 Oct 15.

Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea; Cancer Research Institute, Seoul National University, Seoul, 03080, Republic of Korea; Medical Research Center, Genomic Medicine Institute (GMI), Seoul National University College of Medicine, Seoul, 03080, Korea. Electronic address:

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January 2021

Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway.

Authors:
Jisun Lim Jinbeom Heo Hyein Ju Ji-Woong Shin YongHwan Kim Seungun Lee Hwan Yeul Yu Chae-Min Ryu HongDuck Yun Sujin Song Ki-Sung Hong Hyung-Min Chung Hwa-Ryeon Kim Jae-Seok Roe Kihang Choi In-Gyu Kim Eui Man Jeong Dong-Myung Shin

Sci Adv 2020 Apr 15;6(16):eaba1334. Epub 2020 Apr 15.

Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

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April 2020

Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers.

Authors:
Sung-Yup Cho Yumi Oh Eui Man Jeong Sanghui Park Dakeun Lee Xiaorui Wang Qiqi Zeng Hongyu Qin Fang Hu Hui Gong Xi Liu Guanjun Zhang Deukchae Na Jieun Lee Jeesoo Chae Yun-Suhk Suh Seong-Ho Kong Hyuk-Joon Lee Jong-Il Kim Hansoo Park Chengsheng Zhang Han-Kwang Yang Charles Lee

Exp Mol Med 2020 05 28;52(5):854-864. Epub 2020 May 28.

Department of Life Science, Ewha Womans University, Seoul, Korea.

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May 2020

Antioxidants reduce the heterogeneity of the intracellular glutathione level in senescent cell population of human dermal fibroblasts.

Authors:
Ki Baek Lee Ji-Woong Shin Mee-Ae Kwon Hyewon Kang Hye-Mi Kim Seok-Jin Lee Eui Man Jeong Heun-Soo Kang In-Gyu Kim

J Dermatol Sci 2020 Jun 24;98(3):195-198. Epub 2020 Apr 24.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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June 2020

Keratinocyte transglutaminase 2 promotes CCR6 γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation.

Authors:
Ji-Woong Shin Mee-Ae Kwon Jinha Hwang Seok-Jin Lee Jin-Haeng Lee Hyo-Jun Kim Ki Baek Lee Soo-Jin Lee Eui Man Jeong Jin Ho Chung In-Gyu Kim

Cell Death Dis 2020 04 30;11(4):301. Epub 2020 Apr 30.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.

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April 2020

Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs.

Authors:
Sung-Yup Cho Seungun Lee Jeonghun Yeom Hyo-Jun Kim Jin-Haeng Lee Ji-Woong Shin Mee-Ae Kwon Ki Baek Lee Eui Man Jeong Hee Sung Ahn Dong-Myung Shin Kyunggon Kim In-Gyu Kim

Life Sci Alliance 2020 03 19;3(3). Epub 2020 Feb 19.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

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March 2020

Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2.

Authors:
Eui Man Jeong Ki Baek Lee Gi Eob Kim Chang Min Kim Jin-Haeng Lee Hyo-Jun Kim Ji-Woong Shin Mee-Ae Kwon Hyun Ho Park In-Gyu Kim

Int J Mol Sci 2020 Jan 25;21(3). Epub 2020 Jan 25.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea.

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January 2020

Monitoring Glutathione Dynamics and Heterogeneity in Living Stem Cells.

Authors:
Eui Man Jeong Ji-Woong Shin Jisun Lim Ju Hwan Kim Hyewon Kang Yingfu Yin Hye-Mi Kim YongHwan Kim Sun-Gi Kim Heun-Soo Kang Dong-Myung Shin Kihang Choi In-Gyu Kim

Int J Stem Cells 2019 Jul;12(2):367-379

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea.

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July 2019

Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity.

Authors:
Hyun Ji Ha Sunghark Kwon Eui Man Jeong Chang Min Kim Ki Baek Lee In-Gyu Kim Hyun Ho Park

PLoS One 2018 15;13(10):e0204707. Epub 2018 Oct 15.

School of Pharmacy, Chung-Ang University, Seoul, South Korea.

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March 2019

S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes.

Authors:
Eui Man Jeong Chun Zi Jin Ji Hyun Jang Zai Hao Zhao Chun Li Jin Jin Hang Lee Ki Baek Lee Sung Joon Kim In-Gyu Kim Yin Hua Zhang

Exp Mol Med 2018 04 6;50(4). Epub 2018 Apr 6.

Department of Physiology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Jongno-gu, Seoul, Republic of Korea.

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April 2018

Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function.

Authors:
Eui Man Jeong Ji-Hye Yoon Jisun Lim Ji-Woong Shin A Young Cho Jinbeom Heo Ki Baek Lee Jin-Haeng Lee Won Jong Lee Hyo-Jun Kim Young Hoon Son Seok-Jin Lee Sung-Yup Cho Dong-Myung Shin Kihang Choi In-Gyu Kim

Stem Cell Reports 2018 02 4;10(2):600-614. Epub 2018 Jan 4.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea; Institute of Human-Environment Interface Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea. Electronic address:

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February 2018

Transglutaminase 2 mediates UV-induced skin inflammation by enhancing inflammatory cytokine production.

Authors:
Seok-Jin Lee Ki Baek Lee Young Hoon Son Jiwoong Shin Jin-Haeng Lee Hyo-Jun Kim Ah-Young Hong Hee Won Bae Mee-Ae Kwon Won Jong Lee Jin-Hee Kim Dong Hun Lee Eui Man Jeong In-Gyu Kim

Cell Death Dis 2017 10 26;8(10):e3148. Epub 2017 Oct 26.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.

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October 2017

Transglutaminase 2 regulates osteoclast differentiation via a Blimp1-dependent pathway.

Authors:
Woo-Shin Kim Haemin Kim Eui Man Jeong Hyung Joon Kim Zang Hee Lee In-Gyu Kim Hong-Hee Kim

Sci Rep 2017 09 6;7(1):10626. Epub 2017 Sep 6.

Department of Cell and Developmental Biology, BK21 Program and Dental Research Institute, Seoul National University, Seoul, 03080, Korea.

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September 2017

Sirt1 Regulates DNA Methylation and Differentiation Potential of Embryonic Stem Cells by Antagonizing Dnmt3l.

Authors:
Jinbeom Heo Jisun Lim Seungun Lee Jaeho Jeong Hyunsook Kang YongHwan Kim Jeong Wook Kang Hwan Yeul Yu Eui Man Jeong Kyunggon Kim Magda Kucia Sabine J Waigel Wolfgang Zacharias Yinlu Chen In-Gyu Kim Mariusz Z Ratajczak Dong-Myung Shin

Cell Rep 2017 02;18(8):1930-1945

Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea; Department of Physiology, University of Ulsan College of Medicine, Seoul 05505, Korea. Electronic address:

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February 2017

Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis.

Authors:
Eui Man Jeong Young Hoon Son Yewon Choi Jin-Hee Kim Jin-Haeng Lee Sung-Yup Cho In-Gyu Kim

Exp Mol Med 2016 11 4;48(11):e267. Epub 2016 Nov 4.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, South Korea.

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November 2016

The Role of Interleukin-22 and Its Receptor in the Development and Pathogenesis of Experimental Autoimmune Uveitis.

Authors:
Yejin Kim Tae Wan Kim Yun Seong Park Eui Man Jeong Dong-Sup Lee In-Gyu Kim Hum Chung Young-Il Hwang Wang Jae Lee Hyeong Gon Yu Jae Seung Kang

PLoS One 2016 11;11(5):e0154904. Epub 2016 May 11.

Department of Anatomy, Seoul National University College of Medicine, Seoul, Republic of Korea.

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July 2017

Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease.

Authors:
Chansik Hong Hyemyung Seo Misun Kwak Jeha Jeon Jihoon Jang Eui Man Jeong Jongyun Myeong Yu Jin Hwang Kotdaji Ha Min Jueng Kang Kyu Pil Lee Eugene C Yi In-Gyu Kim Ju-Hong Jeon Hoon Ryu Insuk So

Brain 2015 Oct 30;138(Pt 10):3030-47. Epub 2015 Jun 30.

1 Department of Physiology and Institute of Dermatological Science, Seoul National University College of Medicine, Seoul, 110-799, South Korea

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October 2015

Dexamethasone downregulates caveolin-1 causing muscle atrophy via inhibited insulin signaling.

Authors:
Young Hoon Son Seok-Jin Lee Ki-Baek Lee Jin-Haeng Lee Eui Man Jeong Sun Gun Chung Sang-Chul Park In-Gyu Kim

J Endocrinol 2015 Apr 16;225(1):27-37. Epub 2015 Feb 16.

Department of Biochemistry and Molecular BiologyInstitute of Human-Environment Interface BiologyDepartment of Rehabilitation MedicineSeoul National University College of Medicine, 103 Daehak-ro, Jongno-Gu, Seoul 110-799, Korea Department of Biochemistry and Molecular BiologyInstitute of Human-Environment Interface BiologyDepartment of Rehabilitation MedicineSeoul National University College of Medicine, 103 Daehak-ro, Jongno-Gu, Seoul 110-799, Korea

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April 2015

Cystamine induces AIF-mediated apoptosis through glutathione depletion.

Authors:
Sung-Yup Cho Jin-Haeng Lee Mi-kyeong Ju Eui Man Jeong Hyo-Jun Kim Jisun Lim Seungun Lee Nam-Hyuk Cho Hyun Ho Park Kihang Choi Ju-Hong Jeon In-Gyu Kim

Biochim Biophys Acta 2015 Mar 27;1853(3):619-31. Epub 2014 Dec 27.

Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea; Institute of Human-Environment Interface Biology, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea. Electronic address:

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March 2015