Eugene Redmond

Eugene Redmond

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Eugene Redmond

Eugene Redmond

Publications by authors named "Eugene Redmond"

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ERK-independent African Green monkey pluripotent stem cells in a putative chimera-competent state.

Biochem Biophys Res Commun 2019 02 16;510(1):78-84. Epub 2019 Jan 16.

Axion Research Foundation, Hamden, CT, USA.

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http://dx.doi.org/10.1016/j.bbrc.2019.01.037DOI Listing
February 2019

Human-Monkey Chimeras for Modeling Human Disease: Opportunities and Challenges.

Methods Mol Biol 2019 ;2005:221-231

Axion Research Foundation, Hamden, CT, USA.

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http://dx.doi.org/10.1007/978-1-4939-9524-0_15DOI Listing
January 2019

Human-Monkey Chimeras For Modeling Human Disease: Opportunities and Challenges.

Stem Cells Dev 2018 Oct 15. Epub 2018 Oct 15.

Yale University School of Medicine, New Haven, Connecticut, United States ;

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https://www.liebertpub.com/doi/10.1089/scd.2018.0162
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http://dx.doi.org/10.1089/scd.2018.0162DOI Listing
October 2018

Generating Human Organs via Interspecies Chimera Formation: Advances and Barriers.

Yale J Biol Med 2018 09 21;91(3):333-342. Epub 2018 Sep 21.

Axion Research Foundation, Hamden, CT.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153627PMC
September 2018

Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias.

J Comp Neurol 2017 02 29;525(3):498-512. Epub 2016 Aug 29.

Departments of Psychiatry and Neurosurgery, Yale University, New Haven, Connecticut, 06511.

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http://dx.doi.org/10.1002/cne.24081DOI Listing
February 2017

Impaired Arm Function and Finger Dexterity in a Nonhuman Primate Model of Stroke: Motor and Cognitive Assessments.

Stroke 2016 Apr 8;47(4):1109-16. Epub 2016 Mar 8.

From the Departments of Psychiatry and Neurosurgery, Yale University School of Medicine, New Haven, CT (C.R.S.M., D.E.R.); Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX (G.R.C., A.T., M.M.D.); Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA (G.K.S.); and St Kitts Biomedical Research Foundation, St Kitts, West Indies (D.E.R.).

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http://dx.doi.org/10.1161/STROKEAHA.115.012506DOI Listing
April 2016

Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates.

Front Neurosci 2016 29;10:12. Epub 2016 Jan 29.

Department of Translational Science & Molecular Medicine, Michigan State UniversityGrand Rapids, MI, USA; Hauenstein Neuroscience Center, Mercy Health Saint Mary'sGrand Rapids, MI, USA.

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http://dx.doi.org/10.3389/fnins.2016.00012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731516PMC
February 2016

A potential compensatory role for endogenous striatal tyrosine hydroxylase-positive neurons in a nonhuman primate model of Parkinson's disease.

Cell Transplant 2015 24;24(4):673-80. Epub 2015 Mar 24.

Neuroscience Program, University of Colorado-Denver Anschutz Medical Campus, Denver, CO, USA.

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http://dx.doi.org/10.3727/096368915X687741DOI Listing
December 2015

Survival and integration of neurons derived from human embryonic stem cells in MPTP-lesioned primates.

Cell Transplant 2014 2;23(8):981-94. Epub 2013 Apr 2.

Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.3727/096368913X664865DOI Listing
May 2015

Endometrial stem cell transplantation in MPTP- exposed primates: an alternative cell source for treatment of Parkinson's disease.

J Cell Mol Med 2015 Jan 6;19(1):249-56. Epub 2014 Oct 6.

Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1111/jcmm.12433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288367PMC
January 2015

Primate phencyclidine model of schizophrenia: sex-specific effects on cognition, brain derived neurotrophic factor, spine synapses, and dopamine turnover in prefrontal cortex.

Int J Neuropsychopharmacol 2014 Oct 31;18(6). Epub 2014 Oct 31.

Neuropsychopharmacology Research Unit, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut (Drs Elsworth, Groman, Redmond, and Roth); Department of Psychology and Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California (Dr Jentsch); Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut (Drs Leranth, Kim, and Diano).

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http://dx.doi.org/10.1093/ijnp/pyu048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438537PMC
October 2014

Primate adult brain cell autotransplantation produces behavioral and biological recovery in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian St. Kitts monkeys.

J Comp Neurol 2014 Aug 4;522(12):2729-40. Epub 2014 Apr 4.

Department of Clinical Neurosciences, Lausanne University Hospital, 1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/cne.23579DOI Listing
August 2014

Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.

Stem Cells Transl Med 2014 Jun 17;3(6):692-701. Epub 2014 Apr 17.

Graduate Program in Biomedical Sciences, University of California at San Diego, La Jolla, California, USA; Program in Stem Cell and Regenerative Biology, Sanford-Burnham Medical Research Institute, La Jolla, California, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA; Departments of Psychiatry, Neurosurgery, and Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Neurology, University of Colorado School of Medicine, Denver, Colorado, USA; Department of Neurosurgery and Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts, USA; Gene Therapy Center and Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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http://dx.doi.org/10.5966/sctm.2013-0208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039459PMC
June 2014

Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model.

Mol Ther 2013 Dec 5;21(12):2160-8. Epub 2013 Aug 5.

1] Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA [2] Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/mt.2013.180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863793PMC
December 2013

Coordinated expression of dopamine transporter and vesicular monoamine transporter in the primate striatum during development.

Synapse 2013 Sep 18;67(9):580-5. Epub 2013 Apr 18.

Neuropsychopharmacology Research Laboratory, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA.

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http://dx.doi.org/10.1002/syn.21662DOI Listing
September 2013

Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys.

Int J Neuropsychopharmacol 2013 May 4;16(4):905-12. Epub 2012 Sep 4.

Neuropsychopharmacology Research Unit, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1017/S1461145712000892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733504PMC
May 2013

Using monkeys to understand and cure Parkinson disease.

Authors:
D Eugene Redmond

Hastings Cent Rep 2012 Nov-Dec;Suppl:S7-S11

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http://dx.doi.org/10.1002/hast.100DOI Listing
February 2013

Comparison of fresh to fixed weights of the vervet monkey (Chlorocebus sabaeus) placenta and its relation to gestational age.

J Med Primatol 2012 Jun 1;41(3):158-62. Epub 2012 Feb 1.

Comparative Primate Biology Laboratory, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/j.1600-0684.2011.00534.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360796PMC
June 2012

Determination of fetal age by ultrasonography in St. Kitts green monkeys.

Am J Primatol 2012 May 6;74(5):433-41. Epub 2012 Feb 6.

St. Kitts Biomedical Research Foundation, St. Kitts, West Indies.

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http://doi.wiley.com/10.1002/ajp.22000
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http://dx.doi.org/10.1002/ajp.22000DOI Listing
May 2012

Doublecortin-positive cells in the adult primate cerebral cortex and possible role in brain plasticity and development.

J Comp Neurol 2011 Mar;519(4):775-89

Neurosurgery Research Group, CHUV-UNIL, CH-1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1002/cne.22547DOI Listing
March 2011

Primate adult brain cell autotransplantation, a pilot study in asymptomatic MPTP-treated monkeys.

Cell Transplant 2009 6;18(7):787-99. Epub 2009 Apr 6.

Department of Neurosurgery, Lausanne University Hospital, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.3727/096368909X470847DOI Listing
July 2010

Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles.

Mol Ther 2008 Jul 8;16(7):1252-1260. Epub 2016 Dec 8.

Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. Electronic address:

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http://dx.doi.org/10.1038/mt.2008.100DOI Listing
July 2008

Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.

Exp Neurol 2008 Jun 14;211(2):362-9. Epub 2008 Feb 14.

Department of Pediatrics, Program in Neuroscience, University of Colorado Health Sciences Center, Denver, CO 80045, USA.

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http://dx.doi.org/10.1016/j.expneurol.2008.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483423PMC
June 2008

Clozapine normalizes prefrontal cortex dopamine transmission in monkeys subchronically exposed to phencyclidine.

Neuropsychopharmacology 2008 Feb 16;33(3):491-6. Epub 2007 May 16.

Neuropsychopharmacology Research Unit, Departments of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1038/sj.npp.1301448DOI Listing
February 2008

Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation.

Exp Neurol 2007 Apr 19;204(2):802-7. Epub 2007 Jan 19.

Department of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1016/j.expneurol.2007.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322616PMC
April 2007

Know thyself: autologous cell transplantation strategies for brain repair.

Exp Neurol 2005 Nov 12;196(1):6-8. Epub 2005 Sep 12.

Department of Psychiatry, Yale University School of Medicine, 300 George Street Suite 8107, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1016/j.expneurol.2005.08.014DOI Listing
November 2005

Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey.

J Comp Neurol 2005 Jul;488(2):215-23

Neuropsychopharmacology Research Unit, Departments of Psychiatry and Pharmacology, Yale University School of Medicine, New Haven, CN 06511, USA.

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http://dx.doi.org/10.1002/cne.20599DOI Listing
July 2005

Spatiotemporal patterns of gene expression during fetal monkey brain development.

Brain Res Dev Brain Res 2003 Dec;146(1-2):99-106

Department of Psychiatry, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1016/j.devbrainres.2003.10.001DOI Listing
December 2003

Cellular replacement therapy for Parkinson's disease--where we are today?

Authors:
D Eugene Redmond

Neuroscientist 2002 Oct;8(5):457-88

Department of Psychiatry, Yale University School of Medicine, USA.

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http://dx.doi.org/10.1177/107385802237703DOI Listing
October 2002

Gonadal hormones are responsible for maintaining the integrity of spine synapses in the CA1 hippocampal subfield of female nonhuman primates.

J Comp Neurol 2002 May;447(1):34-42

Department of Obstetrics and Gynecology, Yale University, School of Medicine, New Haven, Connecticut 06520-8063, USA.

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http://dx.doi.org/10.1002/cne.10230DOI Listing
May 2002

Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease.

J Comp Neurol 2002 Jan;442(4):320-30

Department of Neurological Sciences, Research Center for Brain Repair, Rush Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1002/cne.10108DOI Listing
January 2002