Publications by authors named "Etsuko Shibata"

17Publications

A human cancer cell line initiates DNA replication normally in the absence of ORC5 and ORC2 proteins.

J Biol Chem 2020 Sep 28. Epub 2020 Sep 28.

Biochem & Molec Genetics; Pathology, University of Virginia Health Sciences Center, United States.

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http://dx.doi.org/10.1074/jbc.RA120.015450DOI Listing
September 2020

ATAC-seq identifies thousands of extrachromosomal circular DNA in cancer and cell lines.

Sci Adv 2020 May 15;6(20):eaba2489. Epub 2020 May 15.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1126/sciadv.aba2489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228742PMC
May 2020

Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3-mediated gene silencing.

J Biol Chem 2019 11 3;294(45):16930-16941. Epub 2019 Oct 3.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22901

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http://dx.doi.org/10.1074/jbc.RA119.009272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851321PMC
November 2019

ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.

Mol Cell 2017 Oct 21;68(1):61-75.e5. Epub 2017 Sep 21.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22901, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743198PMC
October 2017

Two subunits of human ORC are dispensable for DNA replication and proliferation.

Elife 2016 12 1;5. Epub 2016 Dec 1.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, United States.

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http://dx.doi.org/10.7554/eLife.19084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245961PMC
December 2016

Sequential replication-coupled destruction at G1/S ensures genome stability.

Genes Dev 2015 Aug 13;29(16):1734-46. Epub 2015 Aug 13.

Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA;

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http://dx.doi.org/10.1101/gad.263731.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561482PMC
August 2015

MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.

Nat Commun 2015 Jul 28;6:7744. Epub 2015 Jul 28.

Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Jordan Hall, 1300 Jefferson Park Avenue, Charlottesville, Virginia 22908 USA.

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http://dx.doi.org/10.1038/ncomms8744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525285PMC
July 2015

14-3-3 proteins play a role in the cell cycle by shielding cdt2 from ubiquitin-mediated degradation.

Mol Cell Biol 2014 Nov 25;34(21):4049-61. Epub 2014 Aug 25.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, USA

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00838-14
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http://dx.doi.org/10.1128/MCB.00838-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386460PMC
November 2014

CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase.

J Biol Chem 2014 Aug 24;289(33):23056-64. Epub 2014 Jun 24.

From the Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908

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http://dx.doi.org/10.1074/jbc.M114.574210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132804PMC
August 2014

Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.

J Biol Chem 2013 Oct 10;288(42):30509-14. Epub 2013 Sep 10.

From the Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908.

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http://dx.doi.org/10.1074/jbc.C113.505586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798521PMC
October 2013

Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924.

Mol Cancer Ther 2013 Oct 12;12(10):1958-67. Epub 2013 Aug 12.

Corresponding Author: Amir A. Jazaeri, Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, University of Virginia Health System, Box 800712, Charlottesville, VA 22908.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-1028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795967PMC
October 2013

Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway.

Mol Cell Biol 2013 Aug 17;33(16):3309-20. Epub 2013 Jun 17.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1128/MCB.00358-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753911PMC
August 2013

CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.

Mol Cell 2013 Mar 7;49(6):1147-58. Epub 2013 Mar 7.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.molcel.2013.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615078PMC
March 2013

The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.

Mol Cell Biol 2013 Apr 11;33(8):1632-44. Epub 2013 Feb 11.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1128/MCB.01503-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624244PMC
April 2013

Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.

Mol Cell Biol 2011 Aug 31;31(15):3136-45. Epub 2011 May 31.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.05496-11
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http://dx.doi.org/10.1128/MCB.05496-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147600PMC
August 2011

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation.

Mol Cell 2010 Oct;40(1):9-21

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.molcel.2010.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966975PMC
October 2010

Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage.

Mol Cell Biol 2008 Apr 19;28(8):2690-700. Epub 2008 Feb 19.

Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Jordan 1240, 1300 Jefferson Park Ave., Charlottesville, VA 22908, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.01983-07
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http://dx.doi.org/10.1128/MCB.01983-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2293106PMC
April 2008