Publications by authors named "Etienne Becht"

55Publications

Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor.

Immunity 2020 Aug 23;53(2):303-318.e5. Epub 2020 Jun 23.

Singapore Immunology Network (SIgN), A∗STAR (Agency for Science, Technology and Research), Biopolis, Singapore 138648, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore; State Key Laboratory of Experimental Hematology, Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China; National Cancer Centre Singapore, Singapore 169610, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.005DOI Listing
August 2020

Aggregating transcript-level analyses for single-cell differential gene expression.

Nat Methods 2020 06 1;17(6):583-585. Epub 2020 Jun 1.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41592-020-0854-4DOI Listing
June 2020

Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates.

Immunity 2019 12 19;51(6):1119-1135.e5. Epub 2019 Nov 19.

Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.10.007DOI Listing
December 2019

Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells.

Immunity 2019 09 29;51(3):573-589.e8. Epub 2019 Aug 29.

Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore; Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre, the Academia, 20 College Road, Discovery Tower Level 8, Singapore 169856, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.08.008DOI Listing
September 2019

[Identification of tumor-specific CD8 T cells with a surface marker].

Med Sci (Paris) 2018 12 9;34(12):1032-1034. Epub 2019 Jan 9.

Singapore Immunology Network (SIgN), Agency for science, technology and research, 8A Biomedical Grove, 138648 Singapour.

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https://www.medecinesciences.org/10.1051/medsci/2018286
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http://dx.doi.org/10.1051/medsci/2018286DOI Listing
December 2018

Dimensionality reduction for visualizing single-cell data using UMAP.

Nat Biotechnol 2018 Dec 3. Epub 2018 Dec 3.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://www.nature.com/doifinder/10.1038/nbt.4314
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http://dx.doi.org/10.1038/nbt.4314DOI Listing
December 2018

The clinical role of the TME in solid cancer.

Br J Cancer 2019 01 9;120(1):45-53. Epub 2018 Nov 9.

INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, Team "Cancer, immune control and escape", F-75006, Paris, France.

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http://www.nature.com/articles/s41416-018-0327-z
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http://dx.doi.org/10.1038/s41416-018-0327-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325164PMC
January 2019

Intra-tumoral tertiary lymphoid structures are associated with a low risk of early recurrence of hepatocellular carcinoma.

J Hepatol 2019 01 11;70(1):58-65. Epub 2018 Sep 11.

INSERM UMR_S1138, Centre de Recherche des Cordeliers, Equipe cancer et immunité anti-tumorale, 15 rue de l'Ecole de Médecine, F75006 Paris, France; Université Paris Descartes Paris 5, Sorbonne Paris Cite, UPMC Université Paris 6, F-75006 Paris, France.

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http://dx.doi.org/10.1016/j.jhep.2018.09.003DOI Listing
January 2019

Dynamics of helper CD4 T cells during acute and stable allergic asthma.

Mucosal Immunol 2018 11 7;11(6):1640-1652. Epub 2018 Aug 7.

Singapore Immunology Network (SIgN), Immunos Building at Biopolis, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1038/s41385-018-0057-9DOI Listing
November 2018

Reverse-engineering flow-cytometry gating strategies for phenotypic labelling and high-performance cell sorting.

Bioinformatics 2019 01;35(2):301-308

Singapore Immunology Network, Agency for Science Technology and Research, Singapore.

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http://dx.doi.org/10.1093/bioinformatics/bty491DOI Listing
January 2019

High-Dimensional Profiling of Tumor-Specific Immune Responses: Asking T Cells about What They "See" in Cancer.

Cancer Immunol Res 2018 01;6(1):2-9

Singapore Immunology Network, Agency for Science Technology and Research, Singapore.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0519DOI Listing
January 2018

The Balance Between Cytotoxic T-cell Lymphocytes and Immune Checkpoint Expression in the Prognosis of Colon Tumors.

J Natl Cancer Inst 2018 01;110(1)

Programme "Cartes d'Identité des Tumeurs," Ligue Nationale Contre le Cancer, Paris, France; INSERM, UMRS 938 - Centre de Recherche Saint-Antoine, Equipe "Instabilité des Microsatellites et Cancers," Equipe labellisée par la Ligue Nationale contre le Cancer, Paris, France; Sorbonne Université, UPMC Univ Paris 06, Paris, France; AP-HP, Hôpital Saint-Antoine, Service d'Anatomie et Cytologie Pathologiques, Paris, France; Centre de Recherche en Cancérologie de Toulouse, UMR 1037 INSERM - Université Toulouse III, Department of Pathology, CHU, Toulouse, France; Laboratoire d'Oncopharmacologie, EA 3836, Centre Antoine Lacassagne, Nice, France; INSERM, U682, Développement et Physiopathologie de l'Intestin et du Pancréas, Strasbourg, France; AP-HP, Hôpital Saint-Antoine, Service d'Oncologie Médicale, Paris, France; AP-HP, Laboratoire d'oncogénétique et d'Angiogénétique, GH Pitié-Salpétrière, Paris, France; INSERM, Unité Mixte de Recherche, Paris Sorbonne Cité, Université Paris Descartes, Paris, France; Aix Marseille Univ, INSERM, GMGF, Marseille, France and RGDS, HP Clairval, Marseille, France; AP-HP, Service de Chirurgie Générale et Digestive, Hôpital Saint-Antoine, Paris, France; Department of Oncologic Medicine, Gustave-Roussy, Villejuif, France; Université Paris Descartes, Paris Sorbonne Cité INSERM UMR-S775, Paris, France; INSERM, Burgundy Cancer Registry, U866, Burgundy University, Dijon University Hospital, BP 87900?21079 Dijon, France; Department of Medical Oncology, Centre Georges-François Leclerc, Dijon, France; INSERM, UMR866, Burgundy University; Platform of transfer in oncology, Burgundy University, Centre Georges-François Leclerc, Dijon, France.

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http://dx.doi.org/10.1093/jnci/djx136DOI Listing
January 2018

Transcriptomic analysis of the tumor microenvironment to guide prognosis and immunotherapies.

Cancer Immunol Immunother 2018 06 7;67(6):981-988. Epub 2017 Sep 7.

INSERM, UMR_S 1138, Cordeliers Research Center, Team Cancer, Immune Control and Escape, 75006, Paris, France.

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http://dx.doi.org/10.1007/s00262-017-2058-zDOI Listing
June 2018

PD-L1 Expression and CD8 T-cell Infiltrate are Associated with Clinical Progression in Patients with Node-positive Prostate Cancer.

Eur Urol Focus 2019 03 21;5(2):192-196. Epub 2017 Jun 21.

NET-IMPACT, IRCCS Ospedale San Raffaele, Milan, Italy; Cellular Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2017.05.013DOI Listing
March 2019

Gene expression profiling of circulating tumor cells and peripheral blood mononuclear cells from breast cancer patients.

Oncoimmunology 2016 Apr 10;5(4):e1102827. Epub 2015 Dec 10.

Sotio, a.s., Prague, Czech Republic; Department of Immunology, Charles University, Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1080/2162402X.2015.1102827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839342PMC
April 2016

Immune and Stromal Classification of Colorectal Cancer Is Associated with Molecular Subtypes and Relevant for Precision Immunotherapy.

Clin Cancer Res 2016 Aug 18;22(16):4057-66. Epub 2016 Mar 18.

INSERM UMR_S 1138, Cancer, Immune Control and Escape, Cordeliers Research Centre, Paris, France. Université Paris Descartes, Paris, France. Université Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2879DOI Listing
August 2016

Immune Contexture, Immunoscore, and Malignant Cell Molecular Subgroups for Prognostic and Theranostic Classifications of Cancers.

Adv Immunol 2016 29;130:95-190. Epub 2016 Jan 29.

INSERM UMR_S 1138, Cancer, Immune Control and Escape, Cordeliers Research Centre, Paris, France; Université Paris-Descartes, Sorbonne Paris Cité, UMR_S 1338, Cordeliers Research Centre, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Cordeliers Research Centre, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/bs.ai.2015.12.002DOI Listing
October 2016

Calreticulin Expression in Human Non-Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis.

Cancer Res 2016 04 3;76(7):1746-56. Epub 2016 Feb 3.

Institut National de la Santé et de la Recherche Médicale (INSERM), UMRS1138, Centre de Recherche des Cordeliers, Paris, France. Université Pierre et Marie Curie-Paris 6, UMRS1138, Paris, France. Université Paris Descartes-Paris 5, UMRS1138, Paris, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1142DOI Listing
April 2016

Cancer immune contexture and immunotherapy.

Curr Opin Immunol 2016 Apr 17;39:7-13. Epub 2015 Dec 17.

INSERM UMR_S 1138, Cancer, Immune Control and Escape, Cordeliers Research Centre, Paris, France; Université Paris Descartes, Paris, France; Université Pierre et Marie Curie, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2015.11.009DOI Listing
April 2016

Prognostic and theranostic impact of molecular subtypes and immune classifications in renal cell cancer (RCC) and colorectal cancer (CRC).

Oncoimmunology 2015 Dec 7;4(12):e1049804. Epub 2015 Aug 7.

INSERM UMR_S 1138 Cancer; Immune Control and Escape; Cordeliers Research Centre ; Paris, France ; Université Paris Descartes; Sorbonne Paris Cité; UMR_S 1338; Cordeliers Research Centre ; Paris, France ; Sorbonne Universités; UPMC Univ Paris 06; UMR_S 1138; Cordeliers Research Centre ; Paris, France ; Assistance Publique-Hôpitaux de Paris; Hôpital Européen Georges Pompidou, Department of Biology , Paris, France.

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http://dx.doi.org/10.1080/2162402X.2015.1049804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635888PMC
December 2015

Integrating tumor microenvironment with cancer molecular classifications.

Genome Med 2015 Nov 14;7(1):115. Epub 2015 Nov 14.

INSERM UMR_S 1138, Cancer, Immune Control and Escape, Cordeliers Research Centre, Paris, France.

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http://dx.doi.org/10.1186/s13073-015-0241-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644274PMC
November 2015

The immune response in cancer: from immunology to pathology to immunotherapy.

Virchows Arch 2015 Aug 16;467(2):127-35. Epub 2015 Jun 16.

Cordeliers Research Center, Team 13 Cancer, immune control and escape, INSERM, UMR_S 1138, 75006, Paris, France,

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http://link.springer.com/content/pdf/10.1007%2Fs00428-015-17
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http://link.springer.com/10.1007/s00428-015-1787-7
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http://dx.doi.org/10.1007/s00428-015-1787-7DOI Listing
August 2015

Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer.

Clin Cancer Res 2015 Jul 16;21(13):3031-40. Epub 2015 Feb 16.

INSERM, UMRS 1138, Cordeliers Research Center, Team 13 Cancer, Immune Control and Escape, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, UMRS 1138, Centre de Recherche des Cordeliers, Paris, France. UPMC Univ Paris 06, Sorbonne Universités, UMRS 1138, Centre de Recherche des Cordeliers, Paris, France.

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http://clincancerres.aacrjournals.org/content/21/13/3031.ful
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-2926DOI Listing
July 2015

Molecular subtypes of clear cell renal cell carcinoma are associated with sunitinib response in the metastatic setting.

Clin Cancer Res 2015 Mar 12;21(6):1329-39. Epub 2015 Jan 12.

Inserm, UMR-1162, Génomique fonctionnelle des tumeurs solides, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France. Labex Immuno-oncology, Paris, France. Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Department of Oncology, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1128DOI Listing
March 2015

Shaping of an effective immune microenvironment to and by cancer cells.

Cancer Immunol Immunother 2014 Oct 12;63(10):991-7. Epub 2014 Aug 12.

Laboratory Cancer, Immune Control and Escape, UMRS 1138 INSERM, Cordeliers Research Center, 15, rue de l'école de Médecine, 75270, Paris Cedex 06, France.

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http://dx.doi.org/10.1007/s00262-014-1590-3DOI Listing
October 2014

The new histologic classification of lung primary adenocarcinoma subtypes is a reliable prognostic marker and identifies tumors with different mutation status: the experience of a French cohort.

Chest 2014 Sep;146(3):633-643

INSERM, U1138, Team Cancer, Immune Control, and Escape, Centre de Recherche des Cordeliers, Paris, France; Université Pierre et Marie Curie-Paris 6, Paris, France; Université Paris Descartes-Paris 5, Paris, France; Université Denis Diderot-Paris 7, Paris, France; Service de Pathologie, Paris, France. Electronic address:

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http://dx.doi.org/10.1378/chest.13-2499DOI Listing
September 2014

The immune contexture of primary and metastatic human tumours.

Curr Opin Immunol 2014 Apr 1;27:8-15. Epub 2014 Feb 1.

INSERM UMRS872, Cordeliers Research Center, Immune Microenvironment and Tumours Laboratory, Paris, France; Université Paris Descartes, Paris, France; Université Pierre et Marie Curie, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2014.01.001DOI Listing
April 2014

Dendritic cells in tumor-associated tertiary lymphoid structures signal a Th1 cytotoxic immune contexture and license the positive prognostic value of infiltrating CD8+ T cells.

Cancer Res 2014 Feb 23;74(3):705-15. Epub 2013 Dec 23.

Authors' Affiliations: Laboratory Immune Microenvironment and Tumors, INSERM U872, Cordeliers Research Center; University Pierre et Marie Curie; University Paris Descartes, UMRS 872; Departments of Pathology and Thoracic Surgery, Hôtel Dieu Hospital, AP-HP; Department of Pathology, Institut Mutualiste Montsouris; Department of Immunology, European Georges Pompidou Hospital, AP-HP, Paris, France; and Oncology Research, MedImmune LLC, Gaithersburg, Maryland.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1342DOI Listing
February 2014