Ethan V Abel

Ethan V Abel

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Ethan V Abel

Ethan V Abel

Publications by authors named "Ethan V Abel"

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22Publications

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GM-CSF Mediates Mesenchymal-Epithelial Cross-talk in Pancreatic Cancer.

Cancer Discov 2016 08 16;6(8):886-99. Epub 2016 May 16.

Department of Surgery, University of Michigan, Ann Arbor, Michigan. Pancreatic Cancer Center, University of Michigan, Ann Arbor, Michigan. Translational Oncology Program, University of Michigan, Ann Arbor, Michigan. Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549011PMC
August 2016

The Notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer.

PLoS One 2014 19;9(3):e91983. Epub 2014 Mar 19.

Departments of Surgery, University of Michigan, Ann Arbor, Michigan, United States of America; Department Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America; Department Translational Oncology Program, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091983PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960140PMC
December 2015

FOXD3 modulates migration through direct transcriptional repression of TWIST1 in melanoma.

Mol Cancer Res 2014 Sep 24;12(9):1314-23. Epub 2014 Jul 24.

Department of Cancer Biology and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163536PMC
September 2014

In vivo MAPK reporting reveals the heterogeneity in tumoral selection of resistance to RAF inhibitors.

Cancer Res 2013 Dec 11;73(23):7101-10. Epub 2013 Oct 11.

Authors' Affiliations: Departments of Cancer Biology, Medical Oncology, and Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851924PMC
December 2013

Biology and clinical applications of pancreatic cancer stem cells.

Gastroenterology 2013 Jun;144(6):1241-8

Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1053/j.gastro.2013.01.072DOI Listing
June 2013

Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3.

J Clin Invest 2013 May 1;123(5):2155-68. Epub 2013 Apr 1.

Department of Cancer Biology and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1172/JCI65780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635724PMC
May 2013

SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor.

J Biol Chem 2012 Dec 17;287(50):41797-807. Epub 2012 Oct 17.

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1074/jbc.M112.390906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516728PMC
December 2012

TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells.

Cancer Res 2012 Dec 7;72(24):6382-92. Epub 2012 Dec 7.

Department of Cancer Biology and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531871PMC
December 2012

A homing endonuclease and the 50-nt ribosomal bypass sequence of phage T4 constitute a mobile DNA cassette.

Proc Natl Acad Sci U S A 2011 Sep 19;108(39):16351-6. Epub 2011 Sep 19.

Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.

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http://dx.doi.org/10.1073/pnas.1107633108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182709PMC
September 2011

Finding the root of the problem: the quest to identify melanoma stem cells.

Front Biosci (Schol Ed) 2011 Jun 1;3:937-45. Epub 2011 Jun 1.

Department of Cancer Biology and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535180PMC
http://dx.doi.org/10.2741/198DOI Listing
June 2011

FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells.

Cancer Res 2010 Apr 23;70(7):2891-900. Epub 2010 Mar 23.

Department of Cancer Biology and Kimmel Cancer Center, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848900PMC
April 2010

Mcl-1 is required for melanoma cell resistance to anoikis.

Mol Cancer Res 2009 Apr;7(4):549-56

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689141PMC
April 2009

B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization.

Mol Biol Cell 2008 Feb 28;19(2):498-508. Epub 2007 Nov 28.

Center for Cell Biology and Cancer Research, Albany Medical College, Albany, NY 12208, USA.

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http://dx.doi.org/10.1091/mbc.e07-09-0895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230594PMC
February 2008

Cyclin D3 expression in melanoma cells is regulated by adhesion-dependent phosphatidylinositol 3-kinase signaling and contributes to G1-S progression.

J Biol Chem 2006 Sep 29;281(35):25644-51. Epub 2006 Jun 29.

Center for Cell Biology and Cancer Research, Albany Medical College, Albany, New York 12208, USA.

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http://dx.doi.org/10.1074/jbc.M600197200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266577PMC
September 2006