Ethan G Geier

Ethan G Geier

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Ethan G Geier

Ethan G Geier

Publications by authors named "Ethan G Geier"

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Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 Jun 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

Recent advances in the genetics of frontotemporal dementia.

Curr Genet Med Rep 2019 Mar 30;7(1):41-52. Epub 2019 Jan 30.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1007/s40142-019-0160-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827567PMC
March 2019

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD.

Neurol Genet 2018 Oct 1;4(5):e266. Epub 2018 Oct 1.

Department of Neurology (L.W.B., N.Z.R.S., E.G.G., Z.A.M., B.L.M., W.W.S., J.S.Y.), Memory and Aging Center, University of California, San Francisco; Department of Psychiatry (C.M.K., N.W., A.O.-K.), Washington University, St. Louis, MO; School of Pharmacy (C.M., P.L.), University of Reading, Reading, UK; Laboratory of Neurogenetics (P.M.), Texas Tech University Health Science Center, Lubbock; Department of Molecular Neuroscience (C.M., J.H., P.L., R.F.), UCL Institute of Neurology, London, UK; Department of Radiology and Biomedical Imaging, Neuroradiology Section (C.P.H., R.S.D.), University of California, San Francisco; and Department of Neurology (S.E.B.), University of California, San Francisco.

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http://ng.neurology.org/lookup/doi/10.1212/NXG.0000000000000
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http://dx.doi.org/10.1212/NXG.0000000000000266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167176PMC
October 2018

Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer's Disease.

Front Neurosci 2018 7;12:529. Epub 2018 Aug 7.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fnins.2018.00529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090298PMC
August 2018

Expression and splicing of ABC and SLC transporters in the human blood-brain barrier measured with RNAseq.

Eur J Pharm Sci 2017 May 7;103:47-51. Epub 2017 Feb 7.

College of Medicine, Center for Pharmacogenomics, Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2017.02.010DOI Listing
May 2017

Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression.

Acta Neuropathol Commun 2016 09 2;4(1):98. Epub 2016 Sep 2.

Memory and Aging Center, UCSF, Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s40478-016-0367-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010724PMC
September 2016

Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin.

Mol Pharmacol 2015 Jul 28;88(1):75-83. Epub 2015 Apr 28.

Department of Bioengineering and Therapeutic Sciences (E.C.C., X.L., S.W.Y., E.G.G, S.L.S., K.M.G.) and Institute for Human Genetics (K.M.G.),University of California, San Francisco, California; and Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, China (L.C.)

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http://dx.doi.org/10.1124/mol.114.096776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468641PMC
July 2015

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

Drug Metab Dispos 2014 Aug 22;42(8):1301-13. Epub 2014 May 22.

DMPK and Bioanalytical Research, Abbvie Deutschland GmbH & Co. KG, Ludwigshafen, Germany (M.M., L.L., R.A.B.v.W.); Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Wallingford, Connecticut (M.G.S.); Genentech, Inc., South San Francisco, California (L.S., E.G.G., J.P.); Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania (L.C., D.M.-F., J.Ke.); Janssen Research and Development, LLC, Spring House, Pennsylvania (S.D., J.Ku.); Merck Sharp & Dohme Corporation, Whitehouse Station, New Jersey (X.C., R.E., J.Y., R.E.); Department of Pharmaceutics, University of Washington, Seattle, Washington (B.P., J.D.U.); Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands (A.H.S.); and TaconicArtemis, Koeln, Germany (A.R., N.S.)

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http://dmd.aspetjournals.org/content/early/2014/05/22/dmd.11
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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.114.057976
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http://dx.doi.org/10.1124/dmd.114.057976DOI Listing
August 2014

Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1.

Proc Natl Acad Sci U S A 2013 Apr 18;110(14):5480-5. Epub 2013 Mar 18.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.1218165110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619328PMC
April 2013

Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems.

Clin Cancer Res 2011 Apr 18;17(8):2339-49. Epub 2011 Mar 18.

Departments of Bioengineering and Therapeutic Sciences, UCSF School of Medicine and UCSF Benioff Children's Hospital, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247296PMC
April 2011

Role of the copper transporter, CTR1, in platinum-induced ototoxicity.

J Neurosci 2010 Jul;30(28):9500-9

Departments of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California 94143-0449, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1544-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949060PMC
July 2010