Esther Phielix

Esther Phielix

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Esther Phielix

Esther Phielix

Publications by authors named "Esther Phielix"

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Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial.

EBioMedicine 2019 Nov 31;49:318-330. Epub 2019 Oct 31.

Department of Radiology and Nuclear Medicine, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, the Netherlands; Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945245PMC
November 2019

Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle.

Proc Natl Acad Sci U S A 2018 07 9;115(30):7789-7794. Epub 2018 Jul 9.

Department of Nutrition and Movement Sciences, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1722295115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065021PMC
July 2018

Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial.

Diabetes Care 2016 Dec 6;39(12):2211-2217. Epub 2016 Oct 6.

Department of Human Biology and Human Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands

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http://dx.doi.org/10.2337/dc16-0499DOI Listing
December 2016

ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity.

Diabetologia 2016 May 17;59(5):1030-9. Epub 2016 Feb 17.

Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, P. O. Box 616, 6200MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1007/s00125-016-3885-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826430PMC
May 2016

Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients.

Am J Clin Nutr 2015 Nov 30;102(5):1051-8. Epub 2015 Sep 30.

Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Department of Endocrinology and Diabetology, Medical Faculty, and German Center of Diabetes Research, Partner Düsseldorf, Germany

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http://dx.doi.org/10.3945/ajcn.115.107599DOI Listing
November 2015

Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans.

Diabetes 2015 Apr 28;64(4):1193-201. Epub 2014 Oct 28.

Department of Human Biology, Maastricht University Medical Center, Maastricht, the Netherlands School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands

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http://dx.doi.org/10.2337/db14-0667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375076PMC
April 2015

Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes.

Diabetes 2014 Nov 10;63(11):3856-67. Epub 2014 Jun 10.

Institute for Clinical Diabetology, German Diabetes Center, Düsseldorf, Germany German Center for Diabetes Research, Partner Düsseldorf, Germany Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Düsseldorf, Germany Department of Endocrinology and Diabetology, Heinrich-Heine University, Düsseldorf, Germany

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http://dx.doi.org/10.2337/db13-1794DOI Listing
November 2014

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans.

Proc Natl Acad Sci U S A 2014 Jul 16;111(26):9597-602. Epub 2014 Jun 16.

Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany;German Center for Diabetes Research, Partner Düsseldorf, Düsseldorf, Germany;Department of Endocrinology and Diabetology, University Hospital Düsseldorf, 40225 Düsseldorf, Germany; and

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http://dx.doi.org/10.1073/pnas.1409229111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084449PMC
July 2014

Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial.

Diabetologia 2014 Mar 6;57(3):572-81. Epub 2013 Dec 6.

Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225, Düsseldorf, Germany.

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http://dx.doi.org/10.1007/s00125-013-3127-2DOI Listing
March 2014

Mechanisms underlying the onset of oral lipid-induced skeletal muscle insulin resistance in humans.

Diabetes 2013 Jul 1;62(7):2240-8. Epub 2013 Mar 1.

Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.

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http://dx.doi.org/10.2337/db12-1179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712035PMC
July 2013

Assessing multiple features of mitochondrial function.

Diabetes 2013 Jun;62(6):1826-8

Institute for Clinical Diabetology, German Diabetes Center, Düsseldorf, Germany.

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http://dx.doi.org/10.2337/db13-0303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661614PMC
June 2013

High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance.

Diabetes 2012 Oct 10;61(10):2472-8. Epub 2012 Jul 10.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology, and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.2337/db11-1832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447923PMC
October 2012

Mitochondrial function and insulin resistance during aging: a mini-review.

Gerontology 2011 28;57(5):387-96. Epub 2010 Aug 28.

Institute for Clinical Diabetology, German Diabetes Center, Düsseldorf, Germany.

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https://www.karger.com/Article/FullText/317691
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http://dx.doi.org/10.1159/000317691DOI Listing
April 2012

Enhanced lipid-but not carbohydrate-supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice.

J Cell Physiol 2012 Mar;227(3):1026-33

NUTRIM-School for Nutrition, Toxicology and Metabolism, Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/jcp.22812DOI Listing
March 2012

The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact.

Trends Pharmacol Sci 2011 Oct 6;32(10):607-16. Epub 2011 Aug 6.

Institute for Clinical Diabetology, German Diabetes Center, D-40225, Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.tips.2011.06.006DOI Listing
October 2011

The role of mitochondria in insulin resistance and type 2 diabetes mellitus.

Nat Rev Endocrinol 2011 Sep 13;8(2):92-103. Epub 2011 Sep 13.

Institute for Clinical Diabetology, German Diabetes Center, D-40225 Düsseldorf, Germany.

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http://www.nature.com/articles/nrendo.2011.138
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http://dx.doi.org/10.1038/nrendo.2011.138DOI Listing
September 2011

Stimulation of human whole-body energy expenditure by salsalate is fueled by higher lipid oxidation under fasting conditions and by higher oxidative glucose disposal under insulin-stimulated conditions.

J Clin Endocrinol Metab 2011 May 2;96(5):1415-23. Epub 2011 Feb 2.

NUTRIM School for Nutrition, Toxicology, and Metabolism, Department of Human Movement Sciences, Maastricht University Medical Centre, NL6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1210/jc.2010-1816DOI Listing
May 2011

The use of statins potentiates the insulin-sensitizing effect of exercise training in obese males with and without Type 2 diabetes.

Clin Sci (Lond) 2010 Jun 25;119(7):293-301. Epub 2010 Jun 25.

Department of Human Movement Sciences, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://dx.doi.org/10.1042/CS20100153DOI Listing
June 2010

Type 2 diabetes mellitus and skeletal muscle metabolic function.

Physiol Behav 2008 May 31;94(2):252-8. Epub 2008 Jan 31.

Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, the Netherlands.

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http://dx.doi.org/10.1016/j.physbeh.2008.01.020DOI Listing
May 2008