Publications by authors named "Esther Hulleman"

55Publications

Overview of Current Drug Delivery Methods Across the Blood-Brain Barrier for the Treatment of Primary Brain Tumors.

CNS Drugs 2020 Nov 23;34(11):1121-1131. Epub 2020 Sep 23.

Emma's Children Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40263-020-00766-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658069PMC
November 2020

Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells.

Cell Death Dis 2020 Aug 21;11(8):673. Epub 2020 Aug 21.

Division of Pediatric Hematology and Oncology, Department of Child and Adolescent Health, University Medical Center Goettingen, Robert Koch Straße 40, Goettingen, Germany.

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http://dx.doi.org/10.1038/s41419-020-02800-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442654PMC
August 2020

Development of transient radioresistance during fractionated irradiation in vitro.

Radiother Oncol 2020 Jul 17;148:107-114. Epub 2020 Apr 17.

Amsterdam UMC location VUmc, Department of Radiation Oncology, Cancer Center Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2020.04.014DOI Listing
July 2020

Patient-Derived Orthotopic Xenograft Models of Pediatric Brain Tumors: In a Mature Phase or Still in Its Infancy?

Front Oncol 2019 8;9:1418. Epub 2020 Jan 8.

Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands.

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http://dx.doi.org/10.3389/fonc.2019.01418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960099PMC
January 2020

Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin.

EBioMedicine 2019 Dec 14;50:81-92. Epub 2019 Nov 14.

Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Departments of Pediatric Oncology/Hematology, Emma Children's hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921187PMC
December 2019

Preclinical therapeutic targets in diffuse midline glioma.

Drug Resist Updat 2019 05 7;44:15-25. Epub 2019 Jun 7.

Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.drup.2019.06.001DOI Listing
May 2019

An efficient method for the transduction of primary pediatric glioma neurospheres.

MethodsX 2018 27;5:173-183. Epub 2018 Feb 27.

Departments of Pediatric Oncology/Hematology, Neuro-oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.mex.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318100PMC
February 2018

MELK Inhibition in Diffuse Intrinsic Pontine Glioma.

Clin Cancer Res 2018 11 30;24(22):5645-5657. Epub 2018 Jul 30.

Departments of Pediatric Oncology/Hematology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0924DOI Listing
November 2018

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

J Clin Oncol 2018 07 10;36(19):1963-1972. Epub 2018 May 10.

Lindsey M. Hoffman and Nicholas K. Foreman, University of Colorado Denver; Lindsey M. Hoffman and Nicholas K. Foreman, Children's Hospital Colorado, Aurora, CO; Sophie E.M. Veldhuijzen van Zanten, Esther Hulleman, Gertjan J.L. Kaspers, Esther Sanchez, and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; William P. Vandertop, Academy of Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Niclas Colditz, Marion Hoffmann, Brigitte Bison, Monika Warmuth-Metz, and Christof M. Kramm, University Medical Center Goettingen, Goettingen; Torsten Pietsch and Gerrit H. Gielen, University of Bonn Medical Center, Bonn; David T.W. Jones, Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, German Cancer Research Center, Hopp-Children's Cancer Center at the Nationale Centrum für Tumorerkrankungen Heidelberg, and German Consortium for Translational Cancer Research; Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, Heidelberg University Hospital, Heidelberg, Germany; Joshua Baugh, Brooklyn Chaney, Adam Lane, Christine Fuller, Nancy Yanez Escorza, Renee Doughman, Rachid Drissi, James Leach, Blaise Jones, and Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati; Emmett Broxson, Wright State University and The Children's Medical Center, Dayton, OH; Lili Miles, Nemours Children's Hospital, Orlando, FL; Cynthia Hawkins, Ute Bartels, and Eric Bouffet, The Hospital for Sick Children, Toronto, Ontario; Anne Sophie Carret, Centre Hospitalier Universitaire Sainte-Justine; Nada Jabado, McGill University, Montreal, Quebec, Canada; Stewart Goldman, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL; Sarah Leary, Seattle Children's Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Roger Packer, Children's National Health System; Javad Nazarian, Children's National Medical Center, Washington, DC; Katherine E. Warren, National Cancer Institute, Bethesda, MD; Alberto Broniscer, St Jude Children's Research Hospital, Memphis, TN; Mark W. Kieran, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA; Jane Minturn, Children's Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Melanie Comito, The Pennsylvania State University, Hershey, PA; Chie-Schin Shih, Indiana University, Indianapolis, IN; Soumen Khatua, The University of Texas MD Anderson Cancer Center; Murali Chintagumpala, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX; Timothy Hassall, Lady Cilento Children's Hospital, Brisbane, Queensland; David S. Ziegler, Kids Cancer Centre, Sydney Children's Hospital, Randwick; David S. Ziegler, University of New South Wales, Sydney, New South Wales; Nicholas Gottardo and Hetal Dholaria, Princess Margaret Hospital for Children, Perth, Western Australia, Australia; Martin Benesch, Medical University of Graz, Graz, Austria; Nathalie Boddaert. Stephanie Puget, and Raphaël Calmon, Hôpital Necker Enfants Malades; Pascale Varlet, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris; Géraldine Giraud, David Castel, and Jacques Grill, Gustave Roussy, Université Paris-Sud, Université Paris-Saclay, Villejuif, France; Géraldine Giraud, Uppsala University, Uppsala, Sweden; Chris Jones, The Institute of Cancer Research, Sutton; Darren Hargrave, Great Ormond Street Hospital, London; Guirish A. Solanki, Birmingham Women's and Children's Hospital, Birmingham; Simon Bailey, Great North Children's Hospital, Victoria Wing, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; Piergiorgio Modena and Marzia Giagnacovo, Sant' Anna Como General Hospital, Como; Manila Antonelli, Sapienza University of Rome, Rome; Veronica Biassoni and Maura Massimino, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy; Nicolas U. Gerber and Michael A. Grotzer, University Children's Hospital of Zurich, Zurich; André O. von Bueren, University Hospital of Geneva and University of Geneva, Geneva, Switzerland; and Filip Jadrijevic Cvrlje and Gertjan J.L. Kaspers, Children's Hospital Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1200/JCO.2017.75.9308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075859PMC
July 2018

Signaling pathways and mesenchymal transition in pediatric high-grade glioma.

Cell Mol Life Sci 2018 03 21;75(5):871-887. Epub 2017 Nov 21.

Departments of Pediatric Oncology/Hematology, Neuro-oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00018-017-2714-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809527PMC
March 2018

Trimethylation of H3K27 during human cerebellar development in relation to medulloblastoma.

Oncotarget 2017 Oct 8;8(45):78978-78988. Epub 2017 Sep 8.

Department of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.20741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668013PMC
October 2017

Deceptive morphologic and epigenetic heterogeneity in diffuse intrinsic pontine glioma.

Oncotarget 2017 09 31;8(36):60447-60452. Epub 2017 Jul 31.

VU University Medical Center, Department of Paediatrics, Division of Oncology/Haematology, Amsterdam, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.19726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601151PMC
September 2017

Culture methods of diffuse intrinsic pontine glioma cells determine response to targeted therapies.

Exp Cell Res 2017 11 22;360(2):397-403. Epub 2017 Sep 22.

Departments of Pediatric Oncology / Hematology, Neuro-oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.09.032DOI Listing
November 2017

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.

Cancer Cell 2017 05 20;31(5):635-652.e6. Epub 2017 Apr 20.

Department of Neurology, Stanford University, Palo Alto, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, California 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462626PMC
May 2017

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease.

J Neurooncol 2017 04 21;132(2):255-266. Epub 2017 Jan 21.

Department of Paediatrics, Division of Oncology/Haematology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11060-016-2363-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378734PMC
April 2017

Bevacizumab Targeting Diffuse Intrinsic Pontine Glioma: Results of 89Zr-Bevacizumab PET Imaging in Brain Tumor Models.

Mol Cancer Ther 2016 09 20;15(9):2166-74. Epub 2016 Jun 20.

Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands. Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0558DOI Listing
September 2016

Convection enhanced delivery of carmustine to the murine brainstem: a feasibility study.

J Neurosci Methods 2014 Dec 27;238:88-94. Epub 2014 Sep 27.

Department of Pediatric Oncology, VU University Medical Center, Amsterdam, The Netherlands; Neuro-oncology Research Group, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2014.09.020DOI Listing
December 2014

Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis.

Sci Rep 2014 Jun 11;4:5260. Epub 2014 Jun 11.

1] Department of Neurosurgery, VU University Medical Center, Amsterdam, The Netherlands [2] Neuro-oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands [3] Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/srep05260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052714PMC
June 2014

EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion.

Neuro Oncol 2012 Sep 21;14(9):1125-35. Epub 2012 Jun 21.

Department of Pediatric Oncology/Hematology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, the Netherlands.

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http://dx.doi.org/10.1093/neuonc/nos130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424207PMC
September 2012

EZH2-regulated DAB2IP is a medulloblastoma tumor suppressor and a positive marker for survival.

Clin Cancer Res 2012 Aug 13;18(15):4048-58. Epub 2012 Jun 13.

Neuro-oncology Research Group, Department of Neurosurgery, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-0399DOI Listing
August 2012

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation.

Oncotarget 2011 Dec;2(12):984-96

Department of Pediatric Oncology / Hematology, Neuro-oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282104PMC
http://dx.doi.org/10.18632/oncotarget.362DOI Listing
December 2011

Blood platelets contain tumor-derived RNA biomarkers.

Blood 2011 Sep 10;118(13):3680-3. Epub 2011 Aug 10.

Neuro-oncology Research Group, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-03-344408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224637PMC
September 2011

Expression of the transcription factor HEY1 in glioblastoma: a preliminary clinical study.

Tumori 2010 Jan-Feb;96(1):97-102

Department of Neurosurgery, IRCCS Istituto Clinico Humanitas, Rozzano, Milan, Italy.

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May 2010

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells.

Blood 2009 Feb 31;113(9):2014-21. Epub 2008 Oct 31.

Department of Pediatric Oncology and Hematology, Erasmus Medical Center-Sophia Children's Hospital, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2008-05-157842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081395PMC
February 2009

Molecular mechanisms in gliomagenesis.

Adv Cancer Res 2005 ;94:1-27

European Institute of Oncology, Department of Experimental Oncology, 20141 Milan, Italy.

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http://dx.doi.org/10.1016/S0065-230X(05)94001-3DOI Listing
September 2005