Esther Berrocoso

Esther Berrocoso

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Esther Berrocoso

Publications by authors named "Esther Berrocoso"

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Pain in neuropsychiatry: insights from animal models.

Neurosci Biobehav Rev 2020 May 10. Epub 2020 May 10.

Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Avda. Ana de Viya 21, 11009 Cádiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, 11510 Puerto Real, Cádiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2020.04.029DOI Listing
May 2020

Opioid receptors mRNAs expression and opioids agonist-dependent G-protein activation in the rat brain following neuropathy.

Prog Neuropsychopharmacol Biol Psychiatry 2020 Apr 3;99:109857. Epub 2020 Jan 3.

Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Institute of Health Carlos III, Madrid, Spain; Biomedical Research and Innovation Institute of Cádiz (INiBICA) Research Unit, Puerta del Mar University Hospital, University of Cádiz, Cádiz, Spain; Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, Cádiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2019.109857DOI Listing
April 2020

Monoamines as Drug Targets in Chronic Pain: Focusing on Neuropathic Pain.

Front Neurosci 2019 26;13:1268. Epub 2019 Nov 26.

Neuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cádiz, Cádiz, Spain.

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http://dx.doi.org/10.3389/fnins.2019.01268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951279PMC
November 2019

Monoaminergic system and depression.

Cell Tissue Res 2019 Jul 10;377(1):107-113. Epub 2019 Jan 10.

Department of Psychology, University of Cádiz, 11510 Puerto Real, Cádiz, Spain.

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http://dx.doi.org/10.1007/s00441-018-2978-8DOI Listing
July 2019

Opioid Activity in the Locus Coeruleus Is Modulated by Chronic Neuropathic Pain.

Mol Neurobiol 2019 Jun 3;56(6):4135-4150. Epub 2018 Oct 3.

Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Avda. Ana de Viya, 21, 11009, Cádiz, Spain.

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http://dx.doi.org/10.1007/s12035-018-1361-9DOI Listing
June 2019

Chemogenetic Silencing of the Locus Coeruleus-Basolateral Amygdala Pathway Abolishes Pain-Induced Anxiety and Enhanced Aversive Learning in Rats.

Biol Psychiatry 2019 06 5;85(12):1021-1035. Epub 2019 Mar 5.

Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Institute of Health Carlos III, Madrid, Spain; Biomedical Research Foundation of Cadiz, Puerta del Mar University Hospital, University of Cádiz, Cádiz, Spain; Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, Cádiz, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00063223193012
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http://dx.doi.org/10.1016/j.biopsych.2019.02.018DOI Listing
June 2019

Ketamine promotes rapid and transient activation of AMPA receptor-mediated synaptic transmission in the dorsal raphe nucleus.

Prog Neuropsychopharmacol Biol Psychiatry 2019 01 31;88:243-252. Epub 2018 Jul 31.

Department of Pharmacology, School of Medicine and Nursing, University of the Basque Country UPV/EHU, 48940 Leioa, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2018.07.022DOI Listing
January 2019

The onset of treatment with the antidepressant desipramine is critical for the emotional consequences of neuropathic pain.

Pain 2018 Dec;159(12):2606-2619

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1097/j.pain.0000000000001372DOI Listing
December 2018

Effect of Deep Brain Stimulation of the ventromedial prefrontal cortex on the noradrenergic system in rats.

Brain Stimul 2018 Jan - Feb;11(1):222-230. Epub 2017 Oct 13.

CIBER of Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Cádiz, Spain; Neuropsychopharmacology & Psychobiology Research Group, Department of Psychology, Area of Psychobiology, University of Cádiz, Puerto Real, Cádiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2017.10.003DOI Listing
July 2018

Behavioral effects of combined morphine and MK-801 administration to the locus coeruleus of a rat neuropathic pain model.

Prog Neuropsychopharmacol Biol Psychiatry 2018 06 7;84(Pt A):257-266. Epub 2018 Mar 7.

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Cádiz, Spain; Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, Puerto Real, Cádiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2018.03.007DOI Listing
June 2018

Opioid and noradrenergic contributions of tapentadol to the inhibition of locus coeruleus neurons in the streptozotocin rat model of polyneuropathic pain.

Neuropharmacology 2018 06 15;135:202-210. Epub 2018 Mar 15.

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Cádiz, Spain; Neuropsychopharmacology & Psychobiology Research Group, Psychobiology Area, Department of Psychology, University of Cadiz, Puerto Real (Cádiz), Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00283908183012
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http://dx.doi.org/10.1016/j.neuropharm.2018.03.014DOI Listing
June 2018

Serotonin 5-HT receptor antagonism potentiates the antidepressant activity of citalopram.

Neuropharmacology 2018 05 22;133:491-502. Epub 2018 Feb 22.

Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Spain; Biocruces Health Research Institute, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2018.02.020DOI Listing
May 2018

Discovery and development of tramadol for the treatment of pain.

Expert Opin Drug Discov 2017 12 17;12(12):1281-1291. Epub 2017 Sep 17.

a Neuropsychopharmacology and Psychobiology Research Group, Psychobiology Area, Department of Psychology , University of Cadiz , Puerto Real (Cadiz) , Spain.

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http://dx.doi.org/10.1080/17460441.2017.1377697DOI Listing
December 2017

Single oral dose of cannabinoid derivate loaded PLGA nanocarriers relieves neuropathic pain for eleven days.

Nanomedicine 2017 Nov 26;13(8):2623-2632. Epub 2017 Jul 26.

Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Sevilla, Sevilla, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.07.010DOI Listing
November 2017

Activation of Extracellular Signal-Regulated Kinases (ERK 1/2) in the Locus Coeruleus Contributes to Pain-Related Anxiety in Arthritic Male Rats.

Int J Neuropsychopharmacol 2017 06;20(6):463

Neuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cádiz, Cádiz, Spain (Drs Borges and Mico); Departamento de Biomedicina-Unidade de Biologia Experimental, da Faculdade de Medicina da Universidade do Porto (FMUP), Porto, Portugal (Drs Borges and Neto); Instituto de Biologia Molecular e Celular (IBMC) e Instituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, Portugal (Drs Borges and Neto); Department of Pharmacology, Faculty of Medicine and Dentistry, University of the Basque Country UPV/EHU, Leioa, Spain (Drs Miguelez and Ugedo); Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain (Drs Mico and Berrocoso); Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, Cádiz, Spain (Dr Berrocoso); Instituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Cádiz, Spain (Drs Mico and Berrocoso).

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http://dx.doi.org/10.1093/ijnp/pyx005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458337PMC
June 2017

Building up careers in translational neuroscience and mental health research: Education and training in the Centre for Biomedical Research in Mental Health.

Rev Psiquiatr Salud Ment 2015 Apr-Jun;8(2):65-74. Epub 2015 Feb 12.

Servicio de Psiquiatría Infantil y Adolescente, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, España; Centro de Investigación Biomédica en Red en el área de Salud Mental (CIBERSAM), España.

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http://dx.doi.org/10.1016/j.rpsm.2014.09.003DOI Listing
December 2016

Noradrenergic Locus Coeruleus pathways in pain modulation.

Neuroscience 2016 Dec 4;338:93-113. Epub 2016 Jun 4.

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, 11510 Cádiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2016.05.057DOI Listing
December 2016

Comorbid anxiety-like behavior and locus coeruleus impairment in diabetic peripheral neuropathy: A comparative study with the chronic constriction injury model.

Prog Neuropsychopharmacol Biol Psychiatry 2016 11 17;71:45-56. Epub 2016 Jun 17.

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain; Neuropsychopharmacology and Psychobiology Research Group (CTS-510), Psychobiology Area, Department of Psychology, University of Cadiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2016.06.007DOI Listing
November 2016

Effect of DSP4 and desipramine in the sensorial and affective component of neuropathic pain in rats.

Prog Neuropsychopharmacol Biol Psychiatry 2016 10 12;70:57-67. Epub 2016 May 12.

Neuropsychopharmacology & Psychobiology Research Group, University of Cádiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, 28007 Madrid, Spain; Psychobiology Area, Department of Psychology, University of Cadiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2016.05.002DOI Listing
October 2016

Activation of AMPA Receptors Mediates the Antidepressant Action of Deep Brain Stimulation of the Infralimbic Prefrontal Cortex.

Cereb Cortex 2016 06 17;26(6):2778-2789. Epub 2015 Jun 17.

Department of Neurochemistry and Neuropharmacology, Instituto de Investigaciones Biomédicas de Barcelona, CSIC, IDIBAPS, Barcelona 08036, Spain.

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http://dx.doi.org/10.1093/cercor/bhv133DOI Listing
June 2016

Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease.

Psychoneuroendocrinology 2015 Dec 26;62:69-79. Epub 2015 Jul 26.

Division of Physiology. School of Medicine. Institute of Biomolecules (INBIO). Universidad de Cádiz, Cádiz (Spain). Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2015.07.606DOI Listing
December 2015

Stress Increases the Negative Effects of Chronic Pain on Hippocampal Neurogenesis.

Anesth Analg 2015 Oct;121(4):1078-88

From the *Department of Neuroscience, University of Cádiz, Cádiz, Spain; †CIBER of Mental Health (CIBERSAM), ISCIII, Madrid, Spain; ‡Nursing Faculty "Salus Infirmorum," University of Cádiz, Cádiz, Spain; §Department of Psychology, University of Cádiz, Cádiz, Spain; ∥Faculty Medicine, Department of Neuroscience (Pharmacology and Psychiatry), University of Cádiz, Cádiz, Spain; ¶Faculty Medicine, Department of Pharmacology, University Complutense; and #IIS Hospital 12 de Octubre, Madrid, Spain.

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http://dx.doi.org/10.1213/ANE.0000000000000838DOI Listing
October 2015

ERK1/2: Function, signaling and implication in pain and pain-related anxio-depressive disorders.

Prog Neuropsychopharmacol Biol Psychiatry 2015 Jul 21;60:77-92. Epub 2015 Feb 21.

Departamento de Biologia Experimental, Centro de Investigação Médica da Faculdade de Medicina da Universidade do Porto (CIM-FMUP), 4200-319 Porto, Portugal; Grupo de Morfofisiologia do Sistema Nervoso, Instituto de Biologia Molecular e Celular (IBMC), Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2015.02.010DOI Listing
July 2015

Corticotropin-Releasing Factor Mediates Pain-Induced Anxiety through the ERK1/2 Signaling Cascade in Locus Coeruleus Neurons.

Int J Neuropsychopharmacol 2015 Feb 25;18(8). Epub 2015 Feb 25.

Neuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cádiz, Cádiz, Spain (Ms Borges and Dr Micó); Departamento de Biologia Experimental, Centro de Investigação Médica da Faculdade de Medicina da Universidade do Porto, Porto, Portugal (Ms Borges and Dr Neto); Grupo de Morfofisiologia do Sistema Somatossensitivo, Instituto de Biologia Molecular e Celular, Porto, Portugal (Ms Borges and Dr Neto); Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, Madrid, Spain (Drs Micó and Berrocoso); Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, Cádiz, Spain (Dr Berrocoso).

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http://dx.doi.org/10.1093/ijnp/pyv019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571622PMC
February 2015

Gabapentin, a double-agent acting on cognition in pain?

Authors:
Esther Berrocoso

Pain 2014 Oct 26;155(10):1909-10. Epub 2014 Jun 26.

Neuropsychopharmacology and Psychobiology Research Group, Psychobiology Area, Department of Psychology, University of Cadiz, Cadiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.pain.2014.06.012DOI Listing
October 2014

Pro-/antiinflammatory dysregulation in early psychosis: results from a 1-year follow-up study.

Int J Neuropsychopharmacol 2014 Oct 31;18(2). Epub 2014 Oct 31.

Department of Pharmacology, Faculty of Medicine, Complutense University, Instituto de Investigación Sanitaria -IIS- Hospital 12 de Octubre (i+12), Madrid, Spain (Drs García-Bueno, MacDowell, and Leza); Unitat d'Esquizofrènia Clínic, Hospital Clínic, University of Barcelona, IDIBAPS, Barcelona, Spain (Drs Bioque and Bernardo); Department of Preventive Medicine and Public Health, University of Zaragoza, Zaragoza, Spain (Dr Santabárbara); Hospital Universitario, Alava, EHU/UPV and National Distance Education University, Vitoria, Spain (Drs Martínez-Cengotitabengoa and González-Pinto); Child and Adolescent Psychiatry Department IIS Gregorio Marañón (IISGM), Hospital General Universitario Gregorio Marañón, Madrid, Spain (Drs Moreno and Parellada); Department of Psychiatry, Faculty of Medicine, University of Oviedo, Oviedo, Spain (Drs Sáiz and Bobes); Department of Pharmacology, Faculty of Medicine, University of Cádiz, Cádiz, Spain (Drs Berrocoso and Micó); Department of Pharmacology, Faculty of Medicine, University of Barcelona, Barcelona, Spain (Dr Gassó); Hospital Clínico Universitario, Zaragoza, Spain (Dr Fe Barcones).

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http://dx.doi.org/10.1093/ijnp/pyu037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368893PMC
October 2014

Pain exacerbates chronic mild stress-induced changes in noradrenergic transmission in rats.

Eur Neuropsychopharmacol 2014 Jun 18;24(6):996-1003. Epub 2014 Jan 18.

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, 28007 Madrid, Spain; Neuropsychopharmacology and Psychobiology Research Group, Psychobiology Area, Department of Psychology, University of Cadiz, Campus Universitario Rio San Pedro s/n, 11510 Cádiz, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2014.01.011DOI Listing
June 2014

Reversal of monoarthritis-induced affective disorders by diclofenac in rats.

Anesthesiology 2014 Jun;120(6):1476-90

From the Neuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cádiz, Cádiz, Spain; Departamento de Biologia Experimental, Centro de Investigação Médica da Faculdade de Medicina da Universidade do Porto (CIM-FMUP), Porto, Portugal; Grupo de Morfofisiologia do Sistema Somatossensitivo, Instituto de Biologia Molecular e Celular (IBMC), Porto, Portugal (G.B.); Departamento de Biologia Experimental, Centro de Investigação Médica da Faculdade de Medicina da Universidade do Porto (CIM-FMUP), Porto, Portugal; Grupo de Morfofisiologia do Sistema Somatossensitivo, Instituto de Biologia Molecular e Celular (IBMC) (F.N.); Neuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cádiz, Cádiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Cádiz, Spain (J.A.M.); and Neuropsychopharmacology and Psychobiology Research Group, Department of Psychology, University of Cádiz, Cádiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Cádiz, Spain (E.B.).

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http://dx.doi.org/10.1097/ALN.0000000000000177DOI Listing
June 2014

Fluoxetine: a case history of its discovery and preclinical development.

Expert Opin Drug Discov 2014 May 16;9(5):567-78. Epub 2014 Apr 16.

University of Cadiz, Department of Neuroscience, Neuropsychopharmacology and Psychobiology Research Group , Cádiz 11003 , Spain.

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http://dx.doi.org/10.1517/17460441.2014.907790DOI Listing
May 2014

Social stress exacerbates the aversion to painful experiences in rats exposed to chronic pain: the role of the locus coeruleus.

Pain 2013 Oct 18;154(10):2014-23. Epub 2013 Jun 18.

Neuropsychopharmacology and Psychobiology Research Group, University of Cadiz, Cadiz, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.

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http://dx.doi.org/10.1016/j.pain.2013.06.021DOI Listing
October 2013

The plasticity of the association between mu-opioid receptor and glutamate ionotropic receptor N in opioid analgesic tolerance and neuropathic pain.

Eur J Pharmacol 2013 Sep 13;716(1-3):94-105. Epub 2013 Mar 13.

Neurofarmacología, Instituto de Neurobiología Santiago Ramón y Cajal, Madrid E-28002, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2013.01.066DOI Listing
September 2013

Effect of tapentadol on neurons in the locus coeruleus.

Neuropharmacology 2013 Sep 7;72:250-8. Epub 2013 May 7.

Neuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cadiz, 11003, Spain.

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http://dx.doi.org/10.1016/j.neuropharm.2013.04.053DOI Listing
September 2013

Active behaviours produced by antidepressants and opioids in the mouse tail suspension test.

Int J Neuropsychopharmacol 2013 Feb 5;16(1):151-62. Epub 2012 Jan 5.

Neuropsychopharmacology Research Group, Psychobiology Area, Department of Psychology, University of Cadiz, Cadiz, Spain.

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http://dx.doi.org/10.1017/S1461145711001842DOI Listing
February 2013

Chronic pain leads to concomitant noradrenergic impairment and mood disorders.

Biol Psychiatry 2013 Jan 31;73(1):54-62. Epub 2012 Jul 31.

Neuropsychopharmacology Research Group, Department of Neuroscience, University of Cadiz, Cadiz, Spain.

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http://dx.doi.org/10.1016/j.biopsych.2012.06.033DOI Listing
January 2013

Depressive-like states heighten the aversion to painful stimuli in a rat model of comorbid chronic pain and depression.

Anesthesiology 2012 Sep;117(3):613-25

Department of Neuroscience (Pharmacology and Psychiatry), University of Cádiz, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Cádiz, Spain.

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http://dx.doi.org/10.1097/ALN.0b013e3182657b3eDOI Listing
September 2012

Preclinical discovery of duloxetine for the treatment of depression.

Expert Opin Drug Discov 2012 Aug 10;7(8):745-55. Epub 2012 Jun 10.

Neuropsychopharmacology Research Group, University of Cadiz, Cadiz, Spain.

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http://dx.doi.org/10.1517/17460441.2012.693912DOI Listing
August 2012

Analgesic antidepressants promote the responsiveness of locus coeruleus neurons to noxious stimulation: implications for neuropathic pain.

Pain 2012 Jul 14;153(7):1438-49. Epub 2012 May 14.

Neuropsychopharmacology Research Group, Department of Neuroscience, University of Cadiz, Cadiz, Spain.

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http://dx.doi.org/10.1016/j.pain.2012.03.034DOI Listing
July 2012

The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain.

Psychopharmacology (Berl) 2012 May 29;221(1):53-65. Epub 2011 Oct 29.

Neuropsychopharmacology Research Group, Department of Neuroscience, University of Cadiz, 11003 Cadiz, Spain.

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http://link.springer.com/10.1007/s00213-011-2542-7
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http://dx.doi.org/10.1007/s00213-011-2542-7DOI Listing
May 2012

Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain.

Life Sci 2012 Jan 20;90(1-2):13-20. Epub 2011 Oct 20.

Research & Development in Neuropsychopharmacology Group (PAI CTS-510), Department of Neuroscience, Faculty of Medicine, University of Cadiz, Cadiz, Spain.

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http://dx.doi.org/10.1016/j.lfs.2011.10.002DOI Listing
January 2012

Neurotrophins role in depression neurobiology: a review of basic and clinical evidence.

Curr Neuropharmacol 2011 Dec;9(4):530-52

Instituto de Histologia e Embriologia, Faculdade de Medicina e IBMC, Universidade do Porto, 4200-319, Porto, Portugal.

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http://dx.doi.org/10.2174/157015911798376262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263450PMC
December 2011

Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression.

J Neuroinflammation 2011 Nov 3;8:151. Epub 2011 Nov 3.

Department of Pharmacology, Faculty of Medicine, Universidad Complutense, Madrid 28040, Spain.

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http://dx.doi.org/10.1186/1742-2094-8-151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219571PMC
November 2011

Effects of milnacipran, duloxetine and indomethacin, in polyarthritic rats using the Randall-Selitto model.

Behav Pharmacol 2011 Sep;22(5-6):599-606

Department of Neuroscience (Pharmacology and Psychiatry), Faculty of Medicine, University of Cadiz, Cadiz, Spain.

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http://dx.doi.org/10.1097/FBP.0b013e328345ca4eDOI Listing
September 2011

HCN2 ion channels play a central role in inflammatory and neuropathic pain.

Science 2011 Sep;333(6048):1462-6

Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, UK.

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http://dx.doi.org/10.1126/science.1206243DOI Listing
September 2011

Evaluation of milnacipran, in comparison with amitriptyline, on cold and mechanical allodynia in a rat model of neuropathic pain.

Eur J Pharmacol 2011 Mar 28;655(1-3):46-51. Epub 2011 Jan 28.

Department of Neuroscience (Pharmacology and Psychiatry), Faculty of Medicine, University of Cadiz, 11003 Cadiz, Spain.

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http://dx.doi.org/10.1016/j.ejphar.2011.01.022DOI Listing
March 2011

Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression.

Int J Neuropsychopharmacol 2009 Sep 3;12(8):1033-44. Epub 2009 Apr 3.

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Cádiz, Spain.

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http://dx.doi.org/10.1017/S1461145709000236DOI Listing
September 2009

Opiates as antidepressants.

Curr Pharm Des 2009 ;15(14):1612-22

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Plaza Fragela 9, Cádiz, Spain.

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http://dx.doi.org/10.2174/138161209788168100DOI Listing
July 2009

Role of serotonin 5-HT1A receptors in the antidepressant-like effect and the antinociceptive effect of venlafaxine in mice.

Int J Neuropsychopharmacol 2009 Feb 14;12(1):61-71. Epub 2008 Apr 14.

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Cádiz, Spain.

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http://dx.doi.org/10.1017/S1461145708008766DOI Listing
February 2009

Role of serotonin 5-HT1A and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats.

Psychopharmacology (Berl) 2007 Jul 29;193(1):97-105. Epub 2007 Mar 29.

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Plaza Falla 9, 11003, Cadiz, Spain,

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http://dx.doi.org/10.1007/s00213-007-0761-8DOI Listing
July 2007

In vivo effect of venlafaxine on locus coeruleus neurons: role of opioid, alpha(2)-adrenergic, and 5-hydroxytryptamine(1A) receptors.

J Pharmacol Exp Ther 2007 Jul 12;322(1):101-7. Epub 2007 Apr 12.

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Plaza Fragela 9, 11003 Cádiz, Spain.

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http://dx.doi.org/10.1124/jpet.107.120915DOI Listing
July 2007

The role of 5-HT1A receptors in research strategy for extensive pain treatment.

Curr Top Med Chem 2006 ;6(18):1997-2003

Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, University of Cadiz, Plaza Fragela 9, 11003 Cadiz, Spain.

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http://dx.doi.org/10.2174/156802606778522195DOI Listing
November 2006

Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice.

Psychopharmacology (Berl) 2006 Sep 11;188(1):111-8. Epub 2006 Jul 11.

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Plaza Falla 9, 11003, Cádiz, Spain.

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http://dx.doi.org/10.1007/s00213-006-0464-6DOI Listing
September 2006

In vivo effect of tramadol on locus coeruleus neurons is mediated by alpha2-adrenoceptors and modulated by serotonin.

Neuropharmacology 2006 Jul 30;51(1):146-53. Epub 2006 May 30.

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Plaza Falla 9, E-11003 Cádiz, Spain.

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http://dx.doi.org/10.1016/j.neuropharm.2006.03.013DOI Listing
July 2006

Antidepressants and pain.

Trends Pharmacol Sci 2006 Jul 9;27(7):348-54. Epub 2006 Jun 9.

Pharmacology and Neuroscience Research Group, Department of Neuroscience (Pharmacology and Psychiatry), School of Medicine, University of Cádiz, Plaza Fragela 9, 11003 Cádiz, Spain.

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http://dx.doi.org/10.1016/j.tips.2006.05.004DOI Listing
July 2006

Role of 5-HT1A and 5-HT1B receptors in the antinociceptive effect of tramadol.

Eur J Pharmacol 2005 Mar;511(1):21-6

Pharmacology and Neuroscience Research Group (CTS-510), Department of Neuroscience, Faculty of Medicine, University of Cádiz, Plaza Fragela 9, 11003-Cádiz, Spain.

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http://dx.doi.org/10.1016/j.ejphar.2005.02.006DOI Listing
March 2005

Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.

J Psychopharmacol 2004 Sep;18(3):404-11

Pharmacology and Neuroscience Research Group, Department of Neuroscience, Faculty of Medicine, University of Cádiz, Cádiz, Spain.

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http://dx.doi.org/10.1177/026988110401800305DOI Listing
September 2004

Non-selective opioid receptor antagonism of the antidepressant-like effect of venlafaxine in the forced swimming test in mice.

Neurosci Lett 2004 Jun;363(1):25-8

Pharmacology and Neuroscience Research Group (PAI-510), Department of Neuroscience (Pharmacology and Psychiatry), Faculty of Medicine, University of Cádiz, Plaza Falla, 9, 11003 Cadiz, Spain.

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http://dx.doi.org/10.1016/j.neulet.2004.03.041DOI Listing
June 2004