Publications by authors named "Esteban J Parra"

74Publications

Identification of ancestry proportions in admixed groups across the Americas using clinical pharmacogenomic SNP panels.

Sci Rep 2021 Jan 13;11(1):1007. Epub 2021 Jan 13.

Instituto Nacional de Câncer and Rede Nacional de Farmacogenética, Rio de Janeiro, Brazil.

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January 2021

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.

Authors:
Jonathan P Bradfield Suzanne Vogelezang Janine F Felix Alessandra Chesi Øyvind Helgeland Momoko Horikoshi Ville Karhunen Estelle Lowry Diana L Cousminer Tarunveer S Ahluwalia Elisabeth Thiering Eileen Tai-Hui Boh Mohammad H Zafarmand Natalia Vilor-Tejedor Carol A Wang Raimo Joro Zhanghua Chen William J Gauderman Niina Pitkänen Esteban J Parra Lindsay Fernandez-Rhodes Akram Alyass Claire Monnereau John A Curtin Christian T Have Shana E McCormack Mette Hollensted Christine Frithioff-Bøjsøe Adan Valladares-Salgado Jesus Peralta-Romero Yik-Ying Teo Marie Standl Jaakko T Leinonen Jens-Christian Holm Triinu Peters Jesus Vioque Martine Vrijheid Angela Simpson Adnan Custovic Marc Vaudel Mickaël Canouil Virpi Lindi Mustafa Atalay Mika Kähönen Olli T Raitakari Barbera D C van Schaik Robert I Berkowitz Shelley A Cole V Saroja Voruganti Yujie Wang Heather M Highland Anthony G Comuzzie Nancy F Butte Anne E Justice Sheila Gahagan Estela Blanco Terho Lehtimäki Timo A Lakka Johannes Hebebrand Amélie Bonnefond Niels Grarup Philippe Froguel Leo-Pekka Lyytikäinen Miguel Cruz Sayuko Kobes Robert L Hanson Babette S Zemel Anke Hinney Koon K Teo David Meyre Kari E North Frank D Gilliland Hans Bisgaard Mariona Bustamante Klaus Bonnelykke Craig E Pennell Fernando Rivadeneira André G Uitterlinden Leslie J Baier Tanja G M Vrijkotte Joachim Heinrich Thorkild I A Sørensen Seang-Mei Saw Oluf Pedersen Torben Hansen Johan Eriksson Elisabeth Widén Mark I McCarthy Pål R Njølstad Christine Power Elina Hyppönen Sylvain Sebert Christopher D Brown Marjo-Riitta Järvelin Nicholas J Timpson Stefan Johansson Hakon Hakonarson Vincent W V Jaddoe S F A Grant

Hum Mol Genet 2019 10;28(19):3327-3338

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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October 2019

Population Diversity in Pharmacogenetics: A Latin American Perspective.

Adv Pharmacol 2018 19;83:133-154. Epub 2018 Mar 19.

University of Toronto at Mississauga, Mississauga, ON, Canada.

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July 2019

Fine-mapping of 98 obesity loci in Mexican children.

Int J Obes (Lond) 2019 01 12;43(1):23-32. Epub 2018 Mar 12.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.

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January 2019

Characterization of Large Copy Number Variation in Mexican Type 2 Diabetes subjects.

Sci Rep 2017 12 6;7(1):17105. Epub 2017 Dec 6.

The Centre for Applied Genomics. The Hospital for Sick Children. Peter Gilgan Centre for Research and Learning, 686 Bay Street, Room 139800, Toronto, Ontario, M5G 0A4, Canada.

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December 2017

Quantitative assessment of skin, hair, and iris variation in a diverse sample of individuals and associated genetic variation.

Am J Phys Anthropol 2016 08 10;160(4):570-81. Epub 2015 Sep 10.

Department of Anthropology, University of Toronto Mississauga, Toronto, ON, Canada.

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August 2016

Single nucleotide polymorphism coverage and inference of N-acetyltransferase-2 acetylator phenotypes in wordwide population groups.

Pharmacogenet Genomics 2016 08;26(8):363-9

aCoordenação de Pesquisa, Instituto Nacional de Câncer bPrograma de Computacão Científica, Fundação Oswaldo-Cruz, Rio de Janeiro, Rio de Janeiro, Brazil cDepartment of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario, Canada.

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August 2016

Genome-Wide Studies of Type 2 Diabetes and Lipid Traits in Hispanics.

Curr Diab Rep 2016 May;16(5):41

Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.

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May 2016

Analysis of iris surface features in populations of diverse ancestry.

R Soc Open Sci 2016 Jan 13;3(1):150424. Epub 2016 Jan 13.

Department of Anthropology , University of Toronto Mississauga , Toronto, Ontario, Canada.

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January 2016

JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis.

Bioinformatics 2016 Jan 26;32(2):203-10. Epub 2015 Sep 26.

Department of Computer Science, University of Toronto, M5S 2E4, Toronto, ON, Canada, Genetics and Genome Biology, Hospital for Sick Children, M5G 0A4, Toronto, ON, Canada and.

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January 2016

Association study confirms the role of two OCA2 polymorphisms in normal skin pigmentation variation in East Asian populations.

Am J Hum Biol 2015 Jul-Aug;27(4):520-5. Epub 2015 Mar 23.

Department of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario, Canada.

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April 2016

Evaluation of fall Sun Exposure Score in predicting vitamin D status in young Canadian adults, and the influence of ancestry.

J Photochem Photobiol B 2015 Apr 16;145:25-9. Epub 2015 Feb 16.

Neurosciences and Mental Health Program, Research Institute, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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April 2015

Distribution of two OCA2 polymorphisms associated with pigmentation in East-Asian populations.

Hum Genome Var 2015 10;2:15058. Epub 2015 Dec 10.

Department of Anthropology, University of Toronto at Mississauga , Mississauga, ON, Canada.

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April 2016

Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait.

Am J Hum Genet 2014 Nov 30;95(5):521-34. Epub 2014 Oct 30.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA. Electronic address:

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November 2014

Cuba: exploring the history of admixture and the genetic basis of pigmentation using autosomal and uniparental markers.

PLoS Genet 2014 Jul 24;10(7):e1004488. Epub 2014 Jul 24.

National Centre of Medical Genetics, Medical University of Havana, La Habana, Cuba; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus University, Aarhus, Denmark; Psychiatric Department, Aarhus University Hospital, Aarhus, Denmark.

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July 2014

Demographic history and human genetic diversity: pharmacogenomic implications.

Pharmacogenomics 2014 Feb;15(3):253-6

Department of Anthropology, University of Toronto at Mississauga, Mississauga, Canada.

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February 2014

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Authors:
Anubha Mahajan Min Jin Go Weihua Zhang Jennifer E Below Kyle J Gaulton Teresa Ferreira Momoko Horikoshi Andrew D Johnson Maggie C Y Ng Inga Prokopenko Danish Saleheen Xu Wang Eleftheria Zeggini Goncalo R Abecasis Linda S Adair Peter Almgren Mustafa Atalay Tin Aung Damiano Baldassarre Beverley Balkau Yuqian Bao Anthony H Barnett Ines Barroso Abdul Basit Latonya F Been John Beilby Graeme I Bell Rafn Benediktsson Richard N Bergman Bernhard O Boehm Eric Boerwinkle Lori L Bonnycastle Noël Burtt Qiuyin Cai Harry Campbell Jason Carey Stephane Cauchi Mark Caulfield Juliana C N Chan Li-Ching Chang Tien-Jyun Chang Yi-Cheng Chang Guillaume Charpentier Chien-Hsiun Chen Han Chen Yuan-Tsong Chen Kee-Seng Chia Manickam Chidambaram Peter S Chines Nam H Cho Young Min Cho Lee-Ming Chuang Francis S Collins Marylin C Cornelis David J Couper Andrew T Crenshaw Rob M van Dam John Danesh Debashish Das Ulf de Faire George Dedoussis Panos Deloukas Antigone S Dimas Christian Dina Alex S Doney Peter J Donnelly Mozhgan Dorkhan Cornelia van Duijn Josée Dupuis Sarah Edkins Paul Elliott Valur Emilsson Raimund Erbel Johan G Eriksson Jorge Escobedo Tonu Esko Elodie Eury Jose C Florez Pierre Fontanillas Nita G Forouhi Tom Forsen Caroline Fox Ross M Fraser Timothy M Frayling Philippe Froguel Philippe Frossard Yutang Gao Karl Gertow Christian Gieger Bruna Gigante Harald Grallert George B Grant Leif C Grrop Chrisropher J Groves Elin Grundberg Candace Guiducci Anders Hamsten Bok-Ghee Han Kazuo Hara Neelam Hassanali Andrew T Hattersley Caroline Hayward Asa K Hedman Christian Herder Albert Hofman Oddgeir L Holmen Kees Hovingh Astradur B Hreidarsson Cheng Hu Frank B Hu Jennie Hui Steve E Humphries Sarah E Hunt David J Hunter Kristian Hveem Zafar I Hydrie Hiroshi Ikegami Thomas Illig Erik Ingelsson Muhammed Islam Bo Isomaa Anne U Jackson Tazeen Jafar Alan James Weiping Jia Karl-Heinz Jöckel Anna Jonsson Jeremy B M Jowett Takashi Kadowaki Hyun Min Kang Stavroula Kanoni Wen Hong L Kao Sekar Kathiresan Norihiro Kato Prasad Katulanda Kirkka M Keinanen-Kiukaanniemi Ann M Kelly Hassan Khan Kay-Tee Khaw Chiea-Chuen Khor Hyung-Lae Kim Sangsoo Kim Young Jin Kim Leena Kinnunen Norman Klopp Augustine Kong Eeva Korpi-Hyövälti Sudhir Kowlessur Peter Kraft Jasmina Kravic Malene M Kristensen S Krithika Ashish Kumar Jesus Kumate Johanna Kuusisto Soo Heon Kwak Markku Laakso Vasiliki Lagou Timo A Lakka Claudia Langenberg Cordelia Langford Robert Lawrence Karin Leander Jen-Mai Lee Nanette R Lee Man Li Xinzhong Li Yun Li Junbin Liang Samuel Liju Wei-Yen Lim Lars Lind Cecilia M Lindgren Eero Lindholm Ching-Ti Liu Jian Jun Liu Stéphane Lobbens Jirong Long Ruth J F Loos Wei Lu Jian'an Luan Valeriya Lyssenko Ronald C W Ma Shiro Maeda Reedik Mägi Satu Männisto David R Matthews James B Meigs Olle Melander Andres Metspalu Julia Meyer Ghazala Mirza Evelin Mihailov Susanne Moebus Viswanathan Mohan Karen L Mohlke Andrew D Morris Thomas W Mühleisen Martina Müller-Nurasyid Bill Musk Jiro Nakamura Eitaro Nakashima Pau Navarro Peng-Keat Ng Alexandra C Nica Peter M Nilsson Inger Njølstad Markus M Nöthen Keizo Ohnaka Twee Hee Ong Katharine R Owen Colin N A Palmer James S Pankow Kyong Soo Park Melissa Parkin Sonali Pechlivanis Nancy L Pedersen Leena Peltonen John R B Perry Annette Peters Janini M Pinidiyapathirage Carl G Platou Simon Potter Jackie F Price Lu Qi Venkatesan Radha Loukianos Rallidis Asif Rasheed Wolfgang Rathman Rainer Rauramaa Soumya Raychaudhuri N William Rayner Simon D Rees Emil Rehnberg Samuli Ripatti Neil Robertson Michael Roden Elizabeth J Rossin Igor Rudan Denis Rybin Timo E Saaristo Veikko Salomaa Juha Saltevo Maria Samuel Dharambir K Sanghera Jouko Saramies James Scott Laura J Scott Robert A Scott Ayellet V Segrè Joban Sehmi Bengt Sennblad Nabi Shah Sonia Shah A Samad Shera Xiao Ou Shu Alan R Shuldiner Gunnar Sigurđsson Eric Sijbrands Angela Silveira Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Wing Yee So Alena Stančáková Kari Stefansson Gerald Steinbach Valgerdur Steinthorsdottir Kathleen Stirrups Rona J Strawbridge Heather M Stringham Qi Sun Chen Suo Ann-Christine Syvänen Ryoichi Takayanagi Fumihiko Takeuchi Wan Ting Tay Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Joseph Trakalo Elena Tremoli Mieke D Trip Fuu Jen Tsai Tiinamaija Tuomi Jaakko Tuomilehto Andre G Uitterlinden Adan Valladares-Salgado Sailaja Vedantam Fabrizio Veglia Benjamin F Voight Congrong Wang Nicholas J Wareham Roman Wennauer Ananda R Wickremasinghe Tom Wilsgaard James F Wilson Steven Wiltshire Wendy Winckler Tien Yin Wong Andrew R Wood Jer-Yuarn Wu Ying Wu Ken Yamamoto Toshimasa Yamauchi Mingyu Yang Loic Yengo Mitsuhiro Yokota Robin Young Delilah Zabaneh Fan Zhang Rong Zhang Wei Zheng Paul Z Zimmet David Altshuler Donald W Bowden Yoon Shin Cho Nancy J Cox Miguel Cruz Craig L Hanis Jaspal Kooner Jong-Young Lee Mark Seielstad Yik Ying Teo Michael Boehnke Esteban J Parra Jonh C Chambers E Shyong Tai Mark I McCarthy Andrew P Morris

Nat Genet 2014 Mar 9;46(3):234-44. Epub 2014 Feb 9.

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March 2014

SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican type 2 diabetes patients: a comparative study and meta-analysis.

BMC Med Genet 2013 Oct 11;14:110. Epub 2013 Oct 11.

Biochemistry Research Unit, Hospital de Especialidades, Centro Médico Nacional "Siglo XXI", Instituto Mexicano del Seguro Social, Mexico DF, Mexico.

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October 2013

Exploring signatures of positive selection in pigmentation candidate genes in populations of East Asian ancestry.

BMC Evol Biol 2013 Jul 12;13:150. Epub 2013 Jul 12.

Department of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario, Canada.

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July 2013

The timing of pigmentation lightening in Europeans.

Mol Biol Evol 2013 Jan 25;30(1):24-35. Epub 2012 Aug 25.

IPATIMUP, Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal.

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January 2013

Evaluation of the imputation performance of the program IMPUTE in an admixed sample from Mexico City using several model designs.

BMC Med Genomics 2012 May 1;5:12. Epub 2012 May 1.

Department of Anthropology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, ON, Canada.

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May 2012

Technical note: quantitative measures of iris color using high resolution photographs.

Am J Phys Anthropol 2012 Jan 19;147(1):141-9. Epub 2011 Nov 19.

Department of Anthropology, University of Toronto Mississauga, Ontario, Canada.

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January 2012

Genomic ancestry, self-reported "color" and quantitative measures of skin pigmentation in Brazilian admixed siblings.

PLoS One 2011 2;6(11):e27162. Epub 2011 Nov 2.

Programa de Pós-Graduação em Educação Física, Universidade Católica de Brasília, Brasília, Distrito Federal, Brazil.

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March 2012

Association of vitamin D binding protein (VDBP) polymorphisms and serum 25(OH)D concentrations in a sample of young Canadian adults of different ancestry.

J Steroid Biochem Mol Biol 2011 Nov 12;127(3-5):405-12. Epub 2011 Jun 12.

Department of Anthropology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario L5L 1C6, Canada.

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November 2011

Serum 25-hydroxyvitamin D concentrations fluctuate seasonally in young adults of diverse ancestry living in Toronto.

J Nutr 2010 Dec 27;140(12):2213-20. Epub 2010 Oct 27.

Department of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario, Canada.

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December 2010

Worldwide allele frequency distribution of four polymorphisms associated with warfarin dose requirements.

J Hum Genet 2010 Sep 17;55(9):582-9. Epub 2010 Jun 17.

Department of Anthropology, University of Toronto, Toronto, Ontario, Canada.

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September 2010

Ancestry informative markers and admixture proportions in northeastern Mexico.

J Hum Genet 2009 Sep 14;54(9):504-9. Epub 2009 Aug 14.

Department of Biochemistry and Molecular Medicine, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.

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September 2009

Low wintertime vitamin D levels in a sample of healthy young adults of diverse ancestry living in the Toronto area: associations with vitamin D intake and skin pigmentation.

BMC Public Health 2008 Sep 26;8:336. Epub 2008 Sep 26.

Department of Anthropology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario L5L 1C6, Canada.

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September 2008

Human pigmentation variation: evolution, genetic basis, and implications for public health.

Authors:
Esteban J Parra

Am J Phys Anthropol 2007 ;Suppl 45:85-105

Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada L5L 1C6.

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January 2008

A genomewide admixture mapping panel for Hispanic/Latino populations.

Am J Hum Genet 2007 Jun 20;80(6):1171-8. Epub 2007 Apr 20.

Department of Anthropology, The Pennsylvania State University, University Park, PA 16801, USA.

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June 2007

Admixture in Mexico City: implications for admixture mapping of type 2 diabetes genetic risk factors.

Hum Genet 2007 Feb 26;120(6):807-19. Epub 2006 Oct 26.

Department of Anthropology, University of Toronto at Mississauga, 3359 Mississauga Rd. Room 4026, South Bldg, L5L 1C6, Mississauga, ON, Canada,

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February 2007

What makes a champion? Explaining variation in human athletic performance.

Respir Physiol Neurobiol 2006 Apr 30;151(2-3):109-23. Epub 2006 Jan 30.

Department of Anthropology, 1400 Washington Ave., The University at Albany, SUNY, Albany, NY 12222, USA.

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April 2006

Admixture analysis of a rural population of the state of Guerrero, Mexico.

Am J Phys Anthropol 2005 Dec;128(4):861-9

Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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December 2005

Ancestry explains the blunted ventilatory response to sustained hypoxia and lower exercise ventilation of Quechua altitude natives.

Am J Physiol Regul Integr Comp Physiol 2005 Jul 31;289(1):R225-34. Epub 2005 Mar 31.

Department of Anthropology, 1400 Washington Ave., University at Albany, State University of New York, Albany, NY 12222, USA.

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July 2005

Characterization of admixture in an urban sample from Buenos Aires, Argentina, using uniparentally and biparentally inherited genetic markers.

Hum Biol 2004 Aug;76(4):543-57

Multidisciplinary Institute of Cell Biology, Department of Population Molecular Genetics, La Plata, CP 1900, Buenos Aires, Argentina.

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August 2004

The 8818G allele of the agouti signaling protein (ASIP) gene is ancestral and is associated with darker skin color in African Americans.

Hum Genet 2005 Apr 22;116(5):402-6. Epub 2005 Feb 22.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, 494 Tzagournis Medical Research Facility, 420 W. 12th Avenue, Columbus, OH 43210, USA.

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April 2005

A simple and efficient method for extracting DNA from old and burned bone.

J Forensic Sci 2004 Jul;49(4):754-9

Institute of Forensic Science, Ministry of Public Security, Beijing, China.

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July 2004

Skin responses to ultraviolet radiation: effects of constitutive pigmentation, sex, and ancestry.

Pigment Cell Res 2002 Oct;15(5):385-90

Department of Anthropology, The Pennsylvania State University, PA 16802, USA.

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October 2002

Comparing quantitative measures of erythema, pigmentation and skin response using reflectometry.

Pigment Cell Res 2002 Oct;15(5):379-84

Department of Anthropology, The Pennsylvania State University, University Park, PA, USA.

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October 2002

Melting curve SNP (McSNP) genotyping: a useful approach for diallelic genotyping in forensic science.

J Forensic Sci 2002 May;47(3):593-600

Department of Anthropology, Pennsylvania State University, University Park 16802, USA.

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May 2002