Publications by authors named "Esteban Burchard"

100Publications

Race and Genetic Ancestry in Medicine - A Time for Reckoning with Racism.

N Engl J Med 2021 Jan 6. Epub 2021 Jan 6.

From the Department of Epidemiology and Biostatistics, Graduate School of Public Health and Health Policy, City University of New York, New York (L.N.B.); the Departments of Medicine (J.R.E., J.W., N.B., N.R.P., E.Z., E.G.B.), Pediatrics (E.F.-A., J.W.), Laboratory Medicine (A.H.B.W.), and Epidemiology and Biostatistics (K.B.-D.), Priscilla Chan and Mark Zuckerberg San Francisco General Hospital (K.B.-D., N.R.P.), the Division of General Internal Medicine and the Institute of Human Genetics, Helen Diller Family Comprehensive Cancer Center (E.Z.), and the Department of Bioengineering and Therapeutic Sciences (E.G.B.), University of California, San Francisco, San Francisco, Bay Area Pediatrics, Oakland (M.A.L.), the Department of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte (R.A.K.), and the Department of Neurogenetics, University of California, Los Angeles, Los Angeles (N.A.Z.) - all in California; the Centro de Neumología Pediátrica, San Juan, PR (J.R.R.-S.); Emory University School of Medicine, Atlanta (J.R.G.); and the School of Medicine, University of Virginia, Charlottesville (D.S.W.).

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January 2021

NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity.

J Allergy Clin Immunol 2020 Dec 27. Epub 2020 Dec 27.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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December 2020

Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

Authors:
Alexander G Bick Joshua S Weinstock Satish K Nandakumar Charles P Fulco Erik L Bao Seyedeh M Zekavat Mindy D Szeto Xiaotian Liao Matthew J Leventhal Joseph Nasser Kyle Chang Cecelia Laurie Bala Bharathi Burugula Christopher J Gibson Amy E Lin Margaret A Taub Francois Aguet Kristin Ardlie Braxton D Mitchell Kathleen C Barnes Arden Moscati Myriam Fornage Susan Redline Bruce M Psaty Edwin K Silverman Scott T Weiss Nicholette D Palmer Ramachandran S Vasan Esteban G Burchard Sharon L R Kardia Jiang He Robert C Kaplan Nicholas L Smith Donna K Arnett David A Schwartz Adolfo Correa Mariza de Andrade Xiuqing Guo Barbara A Konkle Brian Custer Juan M Peralta Hongsheng Gui Deborah A Meyers Stephen T McGarvey Ida Yii-Der Chen M Benjamin Shoemaker Patricia A Peyser Jai G Broome Stephanie M Gogarten Fei Fei Wang Quenna Wong May E Montasser Michelle Daya Eimear E Kenny Kari E North Lenore J Launer Brian E Cade Joshua C Bis Michael H Cho Jessica Lasky-Su Donald W Bowden L Adrienne Cupples Angel C Y Mak Lewis C Becker Jennifer A Smith Tanika N Kelly Stella Aslibekyan Susan R Heckbert Hemant K Tiwari Ivana V Yang John A Heit Steven A Lubitz Jill M Johnsen Joanne E Curran Sally E Wenzel Daniel E Weeks Dabeeru C Rao Dawood Darbar Jee-Young Moon Russell P Tracy Erin J Buth Nicholas Rafaels Ruth J F Loos Peter Durda Yongmei Liu Lifang Hou Jiwon Lee Priyadarshini Kachroo Barry I Freedman Daniel Levy Lawrence F Bielak James E Hixson James S Floyd Eric A Whitsel Patrick T Ellinor Marguerite R Irvin Tasha E Fingerlin Laura M Raffield Sebastian M Armasu Marsha M Wheeler Ester C Sabino John Blangero L Keoki Williams Bruce D Levy Wayne Huey-Herng Sheu Dan M Roden Eric Boerwinkle JoAnn E Manson Rasika A Mathias Pinkal Desai Kent D Taylor Andrew D Johnson Paul L Auer Charles Kooperberg Cathy C Laurie Thomas W Blackwell Albert V Smith Hongyu Zhao Ethan Lange Leslie Lange Stephen S Rich Jerome I Rotter James G Wilson Paul Scheet Jacob O Kitzman Eric S Lander Jesse M Engreitz Benjamin L Ebert Alexander P Reiner Siddhartha Jaiswal Gonçalo Abecasis Vijay G Sankaran Sekar Kathiresan Pradeep Natarajan

Nature 2020 10 14;586(7831):763-768. Epub 2020 Oct 14.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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October 2020

A deoxyribonuclease 1-like 3 genetic variant associates with asthma exacerbations.

J Allergy Clin Immunol 2020 Oct 6. Epub 2020 Oct 6.

Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Instituto de Tecnologías Biomédicas, Universidad de La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain. Electronic address:

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October 2020

A genome-wide association study of asthma hospitalizations in adults.

J Allergy Clin Immunol 2020 Sep 2. Epub 2020 Sep 2.

Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa. Electronic address:

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September 2020

Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations.

Pediatr Allergy Immunol 2020 Aug 25. Epub 2020 Aug 25.

Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, San Cristóbal de La Laguna, Tenerife, Spain.

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August 2020

Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma.

Cell Rep 2020 07;32(1):107872

Center for Genes, Environment, and Health, National Jewish Health, Denver, CO 80206, USA; Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado-AMC, Aurora, CO 80045, USA. Electronic address:

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July 2020

Sequencing and imputation in GWAS: Cost-effective strategies to increase power and genomic coverage across diverse populations.

Genet Epidemiol 2020 Sep 9;44(6):537-549. Epub 2020 Jun 9.

Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan.

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September 2020

IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids.

Allergy 2020 04 17;75(4):984-989. Epub 2019 Dec 17.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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April 2020

Atopic dermatitis, race, and genetics.

J Allergy Clin Immunol 2020 01 15;145(1):108-110. Epub 2019 Nov 15.

Department of Medicine, University of California, San Francisco, Calif.

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January 2020

Ancestry-Dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity.

Am J Hum Genet 2019 10 19;105(4):747-762. Epub 2019 Sep 19.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94158, USA; Institute for Human Genetics, University of California San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute, University of California San Francisco, San Francisco, CA 94158, USA; Department of Human Genetics, McGill University, Montreal, QC H3A 0G1, Canada; Genome Quebec Innovation Center, McGill University, Montreal, QC H3A 0G1, Canada. Electronic address:

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October 2019

Bacterial salivary microbiome associates with asthma among african american children and young adults.

Pediatr Pulmonol 2019 12 9;54(12):1948-1956. Epub 2019 Sep 9.

Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology, and Genetics, Universidad de La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain.

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December 2019

Functional genomics of CDHR3 confirms its role in HRV-C infection and childhood asthma exacerbations.

J Allergy Clin Immunol 2019 10 29;144(4):962-971. Epub 2019 Mar 29.

Center for Genes, Environment, and Health, National Jewish Health, Denver, Colo; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, Colo; Department of Pediatrics, National Jewish Health, Denver, Colo. Electronic address:

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October 2019

Acculturation is associated with asthma burden and pulmonary function in Latino youth: The GALA II study.

J Allergy Clin Immunol 2019 05 22;143(5):1914-1922. Epub 2019 Jan 22.

Department of Medicine, University of California, San Francisco, Calif; Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, Calif.

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May 2019

Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas.

Breast Cancer Res 2019 01 14;21(1). Epub 2019 Jan 14.

Division of General Internal Medicine, Department of Medicine, Institute of Human Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, Box 0320, San Francisco, CA, 94143, USA.

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January 2019

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

J Allergy Clin Immunol 2019 06 21;143(6):2062-2074. Epub 2018 Dec 21.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC. Electronic address:

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June 2019

Novel locus for atopic dermatitis in African Americans and replication in European Americans.

J Allergy Clin Immunol 2019 03 9;143(3):1229-1231. Epub 2018 Nov 9.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.

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March 2019

Integrative approach identifies corticosteroid response variant in diverse populations with asthma.

J Allergy Clin Immunol 2019 05 24;143(5):1791-1802. Epub 2018 Oct 24.

Center for Individualized and Genomic Medicine Research (CIGMA), Henry Ford Health System, Detroit, Mich; Department of Internal Medicine, Henry Ford Health System, Detroit, Mich. Electronic address:

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May 2019

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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September 2018

Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants.

Am J Physiol Lung Cell Mol Physiol 2018 11 16;315(5):L858-L869. Epub 2018 Aug 16.

Department of Pediatrics, University of California , San Francisco, California.

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November 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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July 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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August 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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January 2018

Impact of Moderate Alcohol Discontinuation on Insulin Action and Secretion in Latinos With and Without Hepatitis C.

Alcohol Clin Exp Res 2018 Mar 1;42(3):492-499. Epub 2018 Feb 1.

Department of Medicine, University of California, San Francisco, San Francisco, California.

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March 2018

An ancestry-based approach for detecting interactions.

Genet Epidemiol 2018 02 8;42(1):49-63. Epub 2017 Nov 8.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.

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February 2018

Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis.

Pediatr Pulmonol 2017 Dec 30;52(12):1550-1557. Epub 2017 Oct 30.

Department of Pediatrics, University of California, San Francisco, California.

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December 2017

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.

Authors:
Janine F Felix Bonnie R Joubert Andrea A Baccarelli Gemma C Sharp Catarina Almqvist Isabella Annesi-Maesano Hasan Arshad Nour Baïz Marian J Bakermans-Kranenburg Kelly M Bakulski Elisabeth B Binder Luigi Bouchard Carrie V Breton Bert Brunekreef Kelly J Brunst Esteban G Burchard Mariona Bustamante Leda Chatzi Monica Cheng Munthe-Kaas Eva Corpeleijn Darina Czamara Dana Dabelea George Davey Smith Patrick De Boever Liesbeth Duijts Terence Dwyer Celeste Eng Brenda Eskenazi Todd M Everson Fahimeh Falahi M Daniele Fallin Sara Farchi Mariana F Fernandez Lu Gao Tom R Gaunt Akram Ghantous Matthew W Gillman Semira Gonseth Veit Grote Olena Gruzieva Siri E Håberg Zdenko Herceg Marie-France Hivert Nina Holland John W Holloway Cathrine Hoyo Donglei Hu Rae-Chi Huang Karen Huen Marjo-Riitta Järvelin Dereje D Jima Allan C Just Margaret R Karagas Robert Karlsson Wilfried Karmaus Katerina J Kechris Juha Kere Manolis Kogevinas Berthold Koletzko Gerard H Koppelman Leanne K Küpers Christine Ladd-Acosta Jari Lahti Nathalie Lambrechts Sabine A S Langie Rolv T Lie Andrew H Liu Maria C Magnus Per Magnus Rachel L Maguire Carmen J Marsit Wendy McArdle Erik Melén Phillip Melton Susan K Murphy Tim S Nawrot Lorenza Nisticò Ellen A Nohr Björn Nordlund Wenche Nystad Sam S Oh Emily Oken Christian M Page Patrice Perron Göran Pershagen Costanza Pizzi Michelle Plusquin Katri Raikkonen Sarah E Reese Eva Reischl Lorenzo Richiardi Susan Ring Ritu P Roy Peter Rzehak Greet Schoeters David A Schwartz Sylvain Sebert Harold Snieder Thorkild I A Sørensen Anne P Starling Jordi Sunyer Jack A Taylor Henning Tiemeier Vilhelmina Ullemar Marina Vafeiadi Marinus H Van Ijzendoorn Judith M Vonk Annette Vriens Martine Vrijheid Pei Wang Joseph L Wiemels Allen J Wilcox Rosalind J Wright Cheng-Jian Xu Zongli Xu Ivana V Yang Paul Yousefi Hongmei Zhang Weiming Zhang Shanshan Zhao Golareh Agha Caroline L Relton Vincent W V Jaddoe Stephanie J London

Int J Epidemiol 2018 02;47(1):22-23u

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, USA.

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February 2018

Origins of Cancer Disparities in Young Adults: Logic Models to Guide Research.

Am J Prev Med 2017 Sep;53(3S1):S95-S102

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.

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September 2017

Self-reported racial/ethnic discrimination and bronchodilator response in African American youth with asthma.

PLoS One 2017 13;12(6):e0179091. Epub 2017 Jun 13.

Department of Medicine, University of California, San Francisco, San Francisco, California, United States of America.

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October 2017

Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation.

Nat Methods 2017 02;14(3):218-219

Department of Computer Science, University of California, Los Angeles, Los Angeles, California, USA.

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February 2017

An epigenome-wide association study of total serum IgE in Hispanic children.

J Allergy Clin Immunol 2017 Aug 6;140(2):571-577. Epub 2017 Jan 6.

Division of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pa. Electronic address:

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August 2017

Towards Equity in Health: Researchers Take Stock.

PLoS Med 2016 Nov 29;13(11):e1002186. Epub 2016 Nov 29.

Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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November 2016

Predictive Properties of the Asthma Control Test and Its Component Questions for Severe Asthma Exacerbations.

J Allergy Clin Immunol Pract 2017 Jan - Feb;5(1):121-127.e2. Epub 2016 Aug 17.

Department of Internal Medicine, Henry Ford Health System, Detroit, Mich; Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Mich. Electronic address:

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November 2017

What Ancestry Can Tell Us About the Genetic Origins of Inter-Ethnic Differences in Asthma Expression.

Curr Allergy Asthma Rep 2016 07;16(8):53

Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Carretera del Rosario 145, 38010, Santa Cruz de Tenerife, Spain.

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July 2016