Publications by authors named "Esra A Akbay"

33Publications

Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase.

J Biol Chem 2020 Aug 15;295(32):11144-11160. Epub 2020 Jun 15.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

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http://dx.doi.org/10.1074/jbc.RA120.012962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415994PMC
August 2020

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.

Cell Rep 2019 04;27(3):806-819.e5

Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medicine, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193039
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http://dx.doi.org/10.1016/j.celrep.2019.03.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719696PMC
April 2019

Autochthonous murine models for the study of smoker and never-smoker associated lung cancers.

Transl Lung Cancer Res 2018 Aug;7(4):464-486

Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern, Dallas, TX 75208, USA.

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http://dx.doi.org/10.21037/tlcr.2018.06.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131182PMC
August 2018

Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load.

J Clin Invest 2018 08 20;128(9):4179-4191. Epub 2018 Aug 20.

Department of Pathology and Simmons Comprehensive Cancer Center, University of Texas Southwestern (UTSW) Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1172/JCI122095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118636PMC
August 2018

The impact of the MYB-NFIB fusion proto-oncogene in vivo.

Oncotarget 2016 May;7(22):31681-8

Department of Medicine, Dana Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.18632/oncotarget.9426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077968PMC
May 2016

Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models.

Nat Commun 2014 Dec 18;5:5870. Epub 2014 Dec 18.

1] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Lowe Center for Thoracic Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [3] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/ncomms6870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271540PMC
December 2014

Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a Pan-FGFR inhibitor in a mouse model of NSCLC.

Cancer Res 2014 Sep 17;74(17):4676-84. Epub 2014 Jul 17.

Department of Medicine, Dana Farber Cancer Institute, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. Ludwig Institute for Cancer, Cambridge, Massachusetts. Belfer Institute for Applied Cancer Science, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154986PMC
September 2014

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.

Cancer Cell 2014 May 1;25(5):590-604. Epub 2014 May 1.

Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Belfer Institute For Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112370PMC
May 2014

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.

Cancer Discov 2013 Dec 27;3(12):1355-63. Epub 2013 Sep 27.

Departments of 1Medicine and 2Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute; 3Harvard Medical School; 4Ludwig Institute for Cancer Research; 5Department of Neurosurgery, Massachusetts General Hospital; 6Belfer Institute for Applied Cancer Science; 7Department of Pathology, Brigham and Women's Hospital, Boston; 8Broad Institute, Cambridge, Massachusetts; 9UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and 10Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University, Chicago, Illinois; 11Department of Physiology, University of Valencia, Valencia, Spain.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864135PMC
December 2013

Multiple interaction domains in FtsL, a protein component of the widely conserved bacterial FtsLBQ cell division complex.

J Bacteriol 2010 Jun 2;192(11):2757-68. Epub 2010 Apr 2.

Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.

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http://jb.asm.org/content/early/2010/04/02/JB.01609-09.full.
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http://jb.asm.org/cgi/doi/10.1128/JB.01609-09
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http://dx.doi.org/10.1128/JB.01609-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876486PMC
June 2010

Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas.

Cancer Res 2008 Feb;68(3):759-66

Department of Pathology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9072, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5014DOI Listing
February 2008

Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.

Genetics 2007 Sep 29;177(1):179-94. Epub 2007 Jul 29.

Department of Pathology and Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9072, USA.

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http://www.genetics.org/cgi/doi/10.1534/genetics.107.074823
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http://dx.doi.org/10.1534/genetics.107.074823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013718PMC
September 2007