Publications by authors named "Espen Molden"

100Publications

Impairment of endoxifen formation in tamoxifen-treated premenopausal breast cancer patients carrying reduced-function CYP2D6 alleles.

Br J Clin Pharmacol 2020 Jul 26. Epub 2020 Jul 26.

Department of Laboratory Medicine, Clinical Pharmacology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1111/bcp.14500DOI Listing
July 2020

Undetectable or subtherapeutic serum levels of antipsychotic drugs preceding switch to clozapine.

NPJ Schizophr 2020 Jul 17;6(1):17. Epub 2020 Jul 17.

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41537-020-0107-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367852PMC
July 2020

Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs - A study based on blood sample analyses from 24,239 patients.

Eur Neuropsychopharmacol 2020 Aug 25;37:64-69. Epub 2020 Jun 25.

Center for Psychopharmacology, Diakonhjemmet Hospital, PO Box 85 Vinderen, Oslo 0319, Norway; Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1016/j.euroneuro.2020.06.007DOI Listing
August 2020

The Influence of Combined CYP2D6 and CYP2C19 Genotypes on Venlafaxine and O-Desmethylvenlafaxine Concentrations in a Large Patient Cohort.

J Clin Psychopharmacol 2020 Mar/Apr;40(2):137-144

From the Center for Psychopharmacology, Diakonhjemmet Hospital.

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http://dx.doi.org/10.1097/JCP.0000000000001174DOI Listing
March 2020

Fatal liver failure after therapeutic doses of paracetamol in a patient with Duchenne muscular dystrophy and atypical pharmacogenetic profile of drug-metabolizing enzymes.

Basic Clin Pharmacol Toxicol 2020 Jul 5;127(1):47-51. Epub 2020 Feb 5.

Norwegian National Unit for CBRNE Medicine, Department of Acute Medicine, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1111/bcpt.13389DOI Listing
July 2020

Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction - a prospective observational study.

Eur J Clin Pharmacol 2020 May 15;76(5):673-683. Epub 2020 Jan 15.

Department of Internal Medicine, Diakonhjemmet Hospital, PO BOX 23, Vinderen, N-0319, Oslo, Norway.

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http://dx.doi.org/10.1007/s00228-020-02832-0DOI Listing
May 2020

Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients.

Neuropsychopharmacology 2020 02 24;45(3):570-576. Epub 2019 Oct 24.

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41386-019-0554-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969041PMC
February 2020

Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward.

PLoS One 2019 22;14(7):e0220071. Epub 2019 Jul 22.

Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220071PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645516PMC
February 2020

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Nat Genet 2019 Jul;51(7):1193

MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1038/s41588-019-0450-7DOI Listing
July 2019

Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4β-Hydroxycholesterol-an Interaction Study in Healthy Volunteers.

AAPS J 2019 04 24;21(4):58. Epub 2019 Apr 24.

Center for Psychopharmacology, Diakonhjemmet Hospital, PO Box 85, Vinderen, N-0319, Oslo, Norway.

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http://dx.doi.org/10.1208/s12248-019-0330-1DOI Listing
April 2019

Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study.

Lancet Psychiatry 2019 May 15;6(5):418-426. Epub 2019 Apr 15.

Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/S2215-0366(19)30088-4DOI Listing
May 2019

Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI.

Psychoneuroendocrinology 2019 05 6;103:87-95. Epub 2019 Jan 6.

NORMENT & K.G. Jebsen Center for Psychosis Research, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.psyneuen.2019.01.001DOI Listing
May 2019

Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?

J Psychiatr Res 2019 10 13;117:150. Epub 2018 Nov 13.

NORMENT & K.G. Jebsen Center for Psychosis Research, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jpsychires.2018.11.012DOI Listing
October 2019

Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication.

J Psychiatr Res 2018 11 25;106:74-81. Epub 2018 Sep 25.

NORMENT & K.G. Jebsen Center for Psychosis Research, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S00223956183064
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http://dx.doi.org/10.1016/j.jpsychires.2018.09.014DOI Listing
November 2018

Elevated 4β-hydroxycholesterol/cholesterol ratio in anorexia nervosa patients.

Pharmacol Res Perspect 2018 10 11;6(5):e00430. Epub 2018 Sep 11.

Center for Psychopharmacology Diakonhjemmet Hospital Oslo Norway.

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http://dx.doi.org/10.1002/prp2.430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134200PMC
October 2018

Associations between Cytokine Levels and CYP3A4 Phenotype in Patients with Rheumatoid Arthritis.

Drug Metab Dispos 2018 10 10;46(10):1384-1389. Epub 2018 Jul 10.

Center for Psychopharmacology (B.M.W., E.M.), Departments of Rheumatology (S.W.S., E.L.), Internal Medicine (M.V.), and Medicinal Biochemistry (L.L.M.), Diakonhjemmet Hospital, Oslo, Norway; Institute for Experimental Medicinal Research, Oslo University Hospital, Oslo, Norway (M.V.); and Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway (E.M.).

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http://dx.doi.org/10.1124/dmd.118.082065DOI Listing
October 2018

[Who should receive clopidogrel after stroke?].

Tidsskr Nor Laegeforen 2018 05 28;138(9). Epub 2018 May 28.

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http://dx.doi.org/10.4045/tidsskr.18.0277DOI Listing
May 2018

Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker.

Br J Clin Pharmacol 2018 07 10;84(7):1624-1625. Epub 2018 May 10.

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1111/bcp.13606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005591PMC
July 2018

Serumkonsentrasjonsmålinger av DOAK-legemidler.

Tidsskr Nor Laegeforen 2018 04 17;138(7). Epub 2018 Apr 17.

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http://dx.doi.org/10.4045/tidsskr.18.0237DOI Listing
April 2018

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Nat Genet 2018 03 26;50(3):381-389. Epub 2018 Feb 26.

MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1038/s41588-018-0059-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918692PMC
March 2018

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients.

Am J Psychiatry 2018 05 12;175(5):463-470. Epub 2018 Jan 12.

From the Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm; the Department of Physiology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia; the Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo; and the Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo.

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http://dx.doi.org/10.1176/appi.ajp.2017.17050550DOI Listing
May 2018

Utilisation and polypharmacy aspects of antiepileptic drugs in elderly versus younger patients with epilepsy: A pharmacoepidemiological study of CNS-active drugs in Norway, 2004-2015.

Epilepsy Res 2018 01 11;139:35-42. Epub 2017 Nov 11.

Programme for Pharmacy, Department of Life Sciences and Health, Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences, Oslo, Norway; Department of Pharmacology, Oslo University Hospital, Oslo, Norway; The National Center for Epilepsy, Sandvika, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1016/j.eplepsyres.2017.11.001DOI Listing
January 2018

Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy.

Prog Neuropsychopharmacol Biol Psychiatry 2018 03 7;82:263-271. Epub 2017 Nov 7.

NORMENT K.G. Jebsen Center for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo University Hospital, Oslo, Norway; Department of Clinical Neuroscience, Center for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.pnpbp.2017.11.004DOI Listing
March 2018

Individual variability in clinical effect and tolerability of opioid analgesics - Importance of drug interactions and pharmacogenetics.

Scand J Pain 2017 10 17;17:193-200. Epub 2017 Oct 17.

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway; Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.sjpain.2017.09.009DOI Listing
October 2017

Recovery of CYP3A Phenotype after Kidney Transplantation.

Drug Metab Dispos 2017 12 19;45(12):1260-1265. Epub 2017 Sep 19.

Center for Psychopharmacology, Diakonhjemmet Hospital (K.H., T.H., E.M.), Department of Transplantation Medicine (E.S., K.M., A.Å.) and Department of Microbiology (G.B.K.), Oslo University Hospital Rikshospitalet, and Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo (A.O., A.Å., E.M.), Oslo, Norway.

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http://dx.doi.org/10.1124/dmd.117.078030DOI Listing
December 2017

Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment.

Ther Drug Monit 2017 10;39(5):550-555

*Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo; †Department of Addiction Medicine, Haukeland University Hospital, Bergen; ‡Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders, Innlandet Hospital Trust, Hamar; §Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo; ¶Department of Forensic Sciences, Oslo University Hospital, Oslo; and ‖Norwegian Center for Addiction Research, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0000000000000437DOI Listing
October 2017

Hvis du skal gjøre det, gjør det riktig!

Tidsskr Nor Laegeforen 2017 06 26;137(12-13):854. Epub 2017 Jun 26.

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http://tidsskriftet.no/2017/05/kommentar/hvis-du-skal-gjore-
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http://dx.doi.org/10.4045/tidsskr.17.0441DOI Listing
June 2017

Treatment With Antipsychotics in Pregnancy: Changes in Drug Disposition.

Clin Pharmacol Ther 2018 03 19;103(3):477-484. Epub 2017 Sep 19.

Department of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway.

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http://dx.doi.org/10.1002/cpt.770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836849PMC
March 2018

4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients.

Br J Clin Pharmacol 2017 Nov 21;83(11):2398-2405. Epub 2017 Jul 21.

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1111/bcp.13341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651320PMC
November 2017

Response to: 'Response to: Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'.

Br J Clin Pharmacol 2017 06 3;83(6):1357-1358. Epub 2017 Apr 3.

Department of Transplant Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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http://dx.doi.org/10.1111/bcp.13276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427287PMC
June 2017

The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation.

Br J Clin Pharmacol 2017 07 27;83(7):1457-1465. Epub 2017 Feb 27.

Department of Transplant Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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http://dx.doi.org/10.1111/bcp.13248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465334PMC
July 2017

Pharmacokinetic variability, efficacy and tolerability of eslicarbazepine acetate-A national approach to the evaluation of therapeutic drug monitoring data and clinical outcome.

Epilepsy Res 2017 01 5;129:125-131. Epub 2016 Dec 5.

The National Center for Epilepsy, Sandvika, Oslo University Hospital, Oslo, Norway; Dept. of Pharmacology, Oslo University Hospital, Oslo, Norway; Programme for Pharmacy, Dept. of Life Sciences and Health, Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences, Oslo, Norway.

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http://dx.doi.org/10.1016/j.eplepsyres.2016.12.001DOI Listing
January 2017

Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance.

Br J Clin Pharmacol 2017 06 22;83(6):1350-1352. Epub 2016 Dec 22.

Department of Transplant Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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http://dx.doi.org/10.1111/bcp.13188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427239PMC
June 2017

[Safer treatment with serum concentration monitoring of the new anticoagulants?].

Tidsskr Nor Laegeforen 2016 10 11;136(18):1556-1560. Epub 2016 Oct 11.

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http://dx.doi.org/10.4045/tidsskr.16.0255DOI Listing
October 2016

Impact of Ageing on Serum Concentrations of Risperidone and Its Active Metabolite in Patients with Known CYP2D6 Genotype.

Basic Clin Pharmacol Toxicol 2016 Nov 31;119(5):470-475. Epub 2016 May 31.

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1111/bcpt.12614DOI Listing
November 2016

[Genetically determined variation in bioactivation of tamoxifen and clopidogrel].

Tidsskr Nor Laegeforen 2016 Mar 15;136(5):434-6. Epub 2016 Mar 15.

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http://dx.doi.org/10.4045/tidsskr.15.0555DOI Listing
March 2016

Effect of teaching and checklist implementation on accuracy of medication history recording at hospital admission.

Int J Clin Pharm 2016 Feb 20;38(1):20-4. Epub 2015 Nov 20.

Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1007/s11096-015-0218-9DOI Listing
February 2016

Risperidone and Venlafaxine Metabolic Ratios Strongly Predict a CYP2D6 Poor Metabolizing Genotype.

Ther Drug Monit 2016 Feb;38(1):127-34

*Karolinska Institutet, Department of Clinical Science and Education at Södersjukhuset, Stockholm, Sweden; †Department of Pharmacology, Center for Psychopharmacology, Diakonhjemmet Hospital, School of Pharmacy, University of Oslo, Blindern, Norway; ‡Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden; and §Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Norway.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FTD.0000000000000251DOI Listing
February 2016

Effect of CYP2B6*6 on Steady-State Serum Concentrations of Bupropion and Hydroxybupropion in Psychiatric Patients: A Study Based on Therapeutic Drug Monitoring Data.

Ther Drug Monit 2015 Oct;37(5):589-93

*Center for Psychopharmacology, Diakonhjemmet Hospital; †Division of Forensic Sciences, Norwegian Institute of Public Health; and ‡Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0000000000000183DOI Listing
October 2015

Therapeutic Drug Monitoring of Selective Serotonin Reuptake Inhibitors in Elderly Patients.

Ther Drug Monit 2015 Aug;37(4):546-9

*Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo; and †Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://pdfs.journals.lww.com/drug-monitoring/2015/08000/Ther
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http://dx.doi.org/10.1097/FTD.0000000000000169DOI Listing
August 2015

Impact of genetic variability in CYP2D6, CYP3A5, and ABCB1 on serum concentrations of quetiapine and N-desalkylquetiapine in psychiatric patients.

Ther Drug Monit 2015 Apr;37(2):256-61

*Center for Psychopharmacology, Diakonhjemmet Hospital; and †Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Norway.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FTD.0000000000000135DOI Listing
April 2015

Impact of age on serum concentrations of venlafaxine and escitalopram in different CYP2D6 and CYP2C19 genotype subgroups.

Eur J Clin Pharmacol 2014 Aug 27;70(8):933-40. Epub 2014 May 27.

Center for Psychopharmacology, Diakonhjemmet Hospital, PO Box 85 Vinderen, 0319, Oslo, Norway,

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http://dx.doi.org/10.1007/s00228-014-1696-8DOI Listing
August 2014

No influence of CYP3A43 rs472660G> A on steady-state serum olanzapine concentrations in white psychiatric patients.

Pharmacogenet Genomics 2014 May;24(5):272-5

aDepartment of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden bCenter for Psychopharmacology, Diakonhjemmet Hospital cDepartment of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1097/FPC.0000000000000041DOI Listing
May 2014

More potent lipid-lowering effect by rosuvastatin compared with fluvastatin in everolimus-treated renal transplant recipients.

Transplantation 2014 Jun;97(12):1266-71

1 Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway. 2 Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway. 3 Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway. 4 Department of Pharmacology, Oslo University Hospital, Oslo, Norway. 5 Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI. 6 Center of Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway. 7 Department of Nephrology, Drammen Hospital, Drammen, Norway. 8 Address correspondence to: Ida Robertsen, School of Pharmacy, University of Oslo. P. O. Box 1068 Blindern, 0316 Oslo, Norway.

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http://pdfs.journals.lww.com/transplantjournal/2014/06270/Mo
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/01.TP.0000443225.66960.7eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127422PMC
June 2014

Anticholinergic activity in cerebrospinal fluid and serum in individuals with hip fracture with and without delirium.

J Am Geriatr Soc 2014 Jan 2;62(1):94-102. Epub 2014 Jan 2.

Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1111/jgs.12612DOI Listing
January 2014

Serum concentrations of risperidone and aripiprazole in subgroups encoding CYP2D6 intermediate metabolizer phenotype.

Ther Drug Monit 2014 Feb;36(1):80-5

*Center for Psychopharmacology, Diakonhjemmet Hospital; and †Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0000000000000018DOI Listing
February 2014

Association between inherited CYP2D6/2C19 phenotypes and anticholinergic measures in elderly patients using anticholinergic drugs.

Ther Drug Monit 2014 Feb;36(1):125-30

*Department of Geriatric Medicine, Oslo University Hospital; †Department of Pharmaceutical Services, The Hospital Pharmacies; ‡Institute of Clinical Medicine, University of Oslo; §Department of Pharmaceutical Bioscience, School of Pharmacy, University of Oslo; and ¶Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0b013e31829da990DOI Listing
February 2014

Pharmacist-initiated management of antagonistic interactions between anticholinergic drugs and acetyl cholinesterase inhibitors in individuals with dementia.

J Am Geriatr Soc 2013 Sep;61(9):1624-5

Sykehusapotekene HF, Baerum Hospital Pharmacy, Gjettum, Norway.

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http://dx.doi.org/10.1111/jgs.12431DOI Listing
September 2013

Severity and management of drug-drug interactions in acute geriatric patients.

Drugs Aging 2013 Sep;30(9):721-7

Department of Pharmaceutical Services, Oslo Hospital Pharmacy, Sykehusapotekene HF, Oslo, Norway.

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http://dx.doi.org/10.1007/s40266-013-0091-yDOI Listing
September 2013

Influence of CYP1A1/CYP1A2 and AHR polymorphisms on systemic olanzapine exposure.

Pharmacogenet Genomics 2013 May;23(5):279-85

Department of Medical Sciences, Clinical Pharmacology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1097/FPC.0b013e3283602876DOI Listing
May 2013

Cognitive effects of reducing anticholinergic drug burden in a frail elderly population: a randomized controlled trial.

J Gerontol A Biol Sci Med Sci 2013 Mar 14;68(3):271-8. Epub 2012 Sep 14.

Department of Geriatric Medicine, Oslo University Hospital, Norway.

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https://academic.oup.com/biomedgerontology/article-lookup/do
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http://dx.doi.org/10.1093/gerona/gls176DOI Listing
March 2013

Valproic Acid significantly lowers serum concentrations of olanzapine-an interaction effect comparable with smoking.

Ther Drug Monit 2012 Oct;34(5):512-7

Center for Psychopharmacology, Diakonhjemmet Hospital, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0b013e3182693d2aDOI Listing
October 2012

Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.

Drug Metab Dispos 2012 Sep 11;40(9):1778-84. Epub 2012 Jun 11.

Center for Psychopharmacology, Diakonhjemmet Hospital, P.O. Box 85, Vinderen, N-0319 Oslo, Norway.

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http://dx.doi.org/10.1124/dmd.112.045237DOI Listing
September 2012

Statin medication in patients treated with antiepileptic drugs in Norway.

Pharmacoepidemiol Drug Saf 2012 Aug 23;21(8):881-5. Epub 2012 Apr 23.

Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences, Oslo, Norway.

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http://dx.doi.org/10.1002/pds.3287DOI Listing
August 2012

CYP2C19 genetics in fatal carisoprodol intoxications.

Eur J Clin Pharmacol 2012 Nov 15;68(11):1561-5. Epub 2012 Apr 15.

Center for Psychopharmacology, Diakonhjemmet Hospital, Forskningsveien 7, PB 85-Vinderen, 0319, Oslo, Norway.

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http://dx.doi.org/10.1007/s00228-012-1278-6DOI Listing
November 2012

Serum concentrations of antidepressants in the elderly.

Ther Drug Monit 2012 Feb;34(1):25-30

Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0b013e318241dce0DOI Listing
February 2012

[Interactions between metoprolol and antidepressants].

Tidsskr Nor Laegeforen 2011 Sep;131(18):1777-9

Farmasøytisk institutt, Universitetet i Oslo, Norway.

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http://dx.doi.org/10.4045/tidsskr.11.0143DOI Listing
September 2011

OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.

Biochem Pharmacol 2011 Nov 20;82(9):1219-26. Epub 2011 Jul 20.

DMPK Innovative Medicines, AstraZeneca R&D Mölndal, Pepparedsleden 1, SE-431 83 Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.bcp.2011.07.076DOI Listing
November 2011

Evaluation of brain anticholinergic activities of urinary spasmolytic drugs using a high-throughput radio receptor bioassay.

J Am Geriatr Soc 2011 Mar;59(3):501-5

Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1111/j.1532-5415.2010.03307.xDOI Listing
March 2011

Pharmacokinetic variability of quetiapine and the active metabolite N-desalkylquetiapine in psychiatric patients.

Ther Drug Monit 2011 Apr;33(2):222-6

vCenter for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0b013e31821160c4DOI Listing
April 2011

CYP3A5-mediated metabolism of midazolam in recombinant systems is highly sensitive to NADPH-cytochrome P450 reductase activity.

Xenobiotica 2011 Jan 18;41(1):1-5. Epub 2010 Oct 18.

Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Norway.

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http://dx.doi.org/10.3109/00498254.2010.523734DOI Listing
January 2011

Increased frequency of CYP2C9 variant alleles and homozygous VKORC1*2B carriers in warfarin-treated patients with excessive INR response.

Eur J Clin Pharmacol 2010 May 31;66(5):525-30. Epub 2010 Mar 31.

Diakonhjemmet Hospital, Oslo, Norway.

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http://dx.doi.org/10.1007/s00228-010-0813-6DOI Listing
May 2010

Different enzyme kinetics of midazolam in recombinant CYP3A4 microsomes from human and insect sources.

Drug Metab Pharmacokinet 2009 ;24(3):261-8

Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.2133/dmpk.24.261DOI Listing
October 2009

[Rather common, but not indefensible].

Tidsskr Nor Laegeforen 2009 Apr;129(9):891-2

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http://dx.doi.org/10.4045/tidsskr.09.0332DOI Listing
April 2009

[Tobacco smoking and drug interactions].

Tidsskr Nor Laegeforen 2009 Mar;129(7):632-3

Farmasøytisk institutt Universitetet i Oslo Postboks 1068 Blindern 0316 Oslo.

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http://dx.doi.org/10.4045/tidsskr.08.0122DOI Listing
March 2009

Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy.

Br J Clin Pharmacol 2009 Feb 9;67(2):234-41. Epub 2009 Feb 9.

Department of Pharmacoepidemiology, Norwegian Institute of Public Health, P.b. 4404 Nydalen, Oslo, Norway.

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http://dx.doi.org/10.1111/j.1365-2125.2008.03345.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670381PMC
February 2009

[Cytochrome P-450 3A4--the most important arena for drug interactions in the body].

Tidsskr Nor Laegeforen 2008 Dec;128(24):2832-5

Avdeling for klinisk farmakologi St. Olavs Hospital 7006 Trondheim og Institutt for laboratoriemedisin, barne- og kvinnesykdommer Norges teknisk-naturvitenskapelige universitet.

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December 2008

Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5.

Drug Metab Dispos 2009 Feb 20;37(2):254-8. Epub 2008 Nov 20.

Department of Psychopharmacology, Diakonhjemmet Hospital, P.O. Box 85, Vinderen, N-0319 Oslo, Norway.

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http://dx.doi.org/10.1124/dmd.108.023291DOI Listing
February 2009

[A 60-year-old man with heart failure, dry cough and elevated INR values].

Tidsskr Nor Laegeforen 2008 Aug;128(15):1677-9

Hjertesviktpoliklinikken, Lovisenberg Diakonale Sykehus, 0440 Oslo.

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August 2008

Risk management of simvastatin or atorvastatin interactions with CYP3A4 inhibitors.

Drug Saf 2008 ;31(7):587-96

School of Pharmacy, University of Oslo, Oslo, Norway.

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http://link.springer.com/10.2165/00002018-200831070-00004
Publisher Site
http://dx.doi.org/10.2165/00002018-200831070-00004DOI Listing
December 2008

[Fruit and berries--interactions with drugs].

Tidsskr Nor Laegeforen 2007 Dec;127(24):3218-20

Farmasøytisk institutt Universitetet i Oslo Postboks 1068 Blindern 0316 Oslo. espen.moldenfarmasi.uio.no

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December 2007

Impact of the CYP2D6 genotype on steady-state serum concentrations of aripiprazole and dehydroaripiprazole.

Eur J Clin Pharmacol 2007 Dec 9;63(12):1147-51. Epub 2007 Sep 9.

Department of Psychopharmacology, Diakonhjemmet Hospital, PO Box 85, Vinderen, 0319 Oslo, Norway.

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http://dx.doi.org/10.1007/s00228-007-0373-6DOI Listing
December 2007

[Interactions between statins and macrolide antibiotics].

Tidsskr Nor Laegeforen 2007 Jun;127(12):1660-1

Farmasøytisk institutt, Universitetet i Oslo, Postboks 1068 Blindern, 0316 Oslo.

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June 2007

Probable warfarin-simvastatin interaction.

Ann Pharmacother 2007 Jul 12;41(7):1292-5. Epub 2007 Jun 12.

RELIS Medicines Information Centre, Health Region South, Rikshospitalet-Radiumhospitalet Medical Center, Oslo, Norway.

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http://dx.doi.org/10.1345/aph.1K167DOI Listing
July 2007