Ernst Wagner

Pharmaceutical Biotechnology, Center for System-based Drug Research Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich 81377, Germany. Electronic address:

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January 2021

Regional Hyperthermia Enhances Mesenchymal Stem Cell Recruitment to Tumor Stroma: Implications for Mesenchymal Stem Cell-Based Tumor Therapy.

Authors:

Mariella Tutter Christina Schug Kathrin A Schmohl Sarah Urnauer Carolin Kitzberger Nathalie Schwenk Matteo Petrini Christian Zach Sibylle Ziegler Peter Bartenstein Wolfgang A Weber Gabriele Multhoff Ernst Wagner Lars H Lindner Peter J Nelson Christine Spitzweg

Mol Ther 2021 02 15;29(2):788-803. Epub 2020 Oct 15.

Department of Internal Medicine IV, University Hospital, LMU Munich, 81377 Munich, Germany; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, MN, USA. Electronic address:

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February 2021

A Multistage Cooperative Nanoplatform Enables Intracellular Co-Delivery of Proteins and Chemotherapeutics for Cancer Therapy.

Authors:

Peng Zhang Yu Zhang Xiaoya Ding Wei Shen Mingqian Li Ernst Wagner Chunsheng Xiao Xuesi Chen

Adv Mater 2020 Nov 9;32(46):e2000013. Epub 2020 Oct 9.

Key Laboratory of Polymer Ecomaterials, Jilin Biomedical Polymers Engineering Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.

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November 2020

Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization.

Authors:

Yanfang Wang Ernst Wagner

Pharmaceutics 2020 Sep 18;12(9). Epub 2020 Sep 18.

Pharmaceutical Biotechnology, Center for System-based Drug Research, Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, D-81377 Munich, Germany.

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September 2020

Nucleic Acid-Based Approaches for Tumor Therapy.

Authors:

Simone Hager Frederic Julien Fittler Ernst Wagner Matthias Bros

Cells 2020 09 9;9(9). Epub 2020 Sep 9.

Department of Dermatology, University Medical Center, 55131 Mainz, Germany.

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September 2020

Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles.

Authors:

Lisa Haddick Wei Zhang Sören Reinhard Karin Möller Hanna Engelke Ernst Wagner Thomas Bein

Pharmaceutics 2020 Jun 2;12(6). Epub 2020 Jun 2.

Department of Chemistry and Center for NanoScience, University of Munich (LMU), Butenandtstrasse 5-13, 81377 Munich, Germany.

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June 2020

Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter () gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells.

Authors:

Mariella Tutter Christina Schug Kathrin A Schmohl Sarah Urnauer Nathalie Schwenk Matteo Petrini Wouter J M Lokerse Christian Zach Sibylle Ziegler Peter Bartenstein Wolfgang A Weber Ernst Wagner Lars H Lindner Peter J Nelson Christine Spitzweg

Theranostics 2020 15;10(10):4490-4506. Epub 2020 Mar 15.

Department of Internal Medicine IV, University Hospital of Munich, LMU Munich, Munich, Germany.

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March 2020

Protein-drug conjugate programmed by pH-reversible linker for tumor hypoxia relief and enhanced cancer combination therapy.

Authors:

Xican Zhang Liangzhu Feng Ziliang Dong Xiaoqian Xin Zhijuan Yang Dashi Deng Ernst Wagner Zhuang Liu Xiaowen Liu

Int J Pharm 2020 May 11;582:119321. Epub 2020 Apr 11.

Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China. Electronic address:

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May 2020

Optimizing synthetic nucleic acid and protein nanocarriers: The chemical evolution approach.

Authors:

Franziska Freitag Ernst Wagner

Adv Drug Deliv Rev 2021 01 1;168:30-54. Epub 2020 Apr 1.

Pharmaceutical Biotechnology, Center for System-Based Drug Research, Ludwig-Maximilians-Universität (LMU), Munich, Germany; Center for Nanoscience (CeNS), Ludwig-Maximilians-Universität (LMU), Munich, Germany. Electronic address:

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January 2021

Artificial peptides for antitumoral siRNA delivery.

Authors:

Jie Luo Ernst Wagner Yanfang Wang

J Mater Chem B 2020 03;8(10):2020-2031

Pharmaceutical Biotechnology, Center for System-based Drug Research Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, D-81377 Munich, Germany.

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March 2020

Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides.

Authors:

Jasmin Kuhn Yi Lin Ana Krhac Levacic Nader Al Danaf Lun Peng Miriam Höhn Don C Lamb Ernst Wagner Ulrich Lächelt

Bioconjug Chem 2020 03 3;31(3):729-742. Epub 2020 Feb 3.

Department of Pharmacy, Ludwig-Maximilians-Universität München, Munich 81377, Germany.

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March 2020

Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A.

Authors:

Bojan Ljepoja Christoph Schreiber Florian A Gegenfurtner Jonathan García-Roman Bianca Köhler Stefan Zahler Joachim O Rädler Ernst Wagner Andreas Roidl

PLoS One 2019 20;14(11):e0224314. Epub 2019 Nov 20.

Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, Munich, Germany.

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April 2020

Downregulation of GRK5 hampers the migration of breast cancer cells.

Authors:

Ann-Katrin Sommer Mathias Falcenberg Bojan Ljepoja Thomas Fröhlich Georg J Arnold Ernst Wagner Andreas Roidl

Sci Rep 2019 10 29;9(1):15548. Epub 2019 Oct 29.

Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, D-81377, Munich, Germany.

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October 2019

Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions.

Authors:

Lun Peng Ernst Wagner

Biomacromolecules 2019 10 20;20(10):3613-3626. Epub 2019 Sep 20.

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October 2019

Click-Shielded and Targeted Lipopolyplexes.

Authors:

Philipp Michael Klein Ernst Wagner

Methods Mol Biol 2019 ;2036:141-164

Pharmaceutical Biotechnology, Center for System-based Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.

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April 2020

Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells.

Authors:

Ines Truebenbach Wei Zhang Yanfang Wang Sarah Kern Miriam Höhn Sören Reinhard Jan Gorges Uli Kazmaier Ernst Wagner

Int J Pharm 2019 Oct 26;569:118570. Epub 2019 Jul 26.

Pharmaceutical Biotechnology, Center for System-Based Drug Research, and Center for Nanoscience (CeNS), Ludwig-Maximilians-Universität, 81377 Munich, Germany. Electronic address:

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October 2019

Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell-Mediated Sodium Iodide Symporter () Gene I Therapy.

Authors:

Christina Schug Carolin Kitzberger Wolfgang Sievert Rebekka Spellerberg Mariella Tutter Kathrin A Schmohl Bernadette Eberlein Tilo Biedermann Katja Steiger Christian Zach Markus Schwaiger Gabriele Multhoff Ernst Wagner Peter J Nelson Christine Spitzweg

Clin Cancer Res 2019 10 13;25(19):5997-6008. Epub 2019 Jun 13.

Medizinische Klinik und Poliklinik IV-Campus Grosshadern, University Hospital of Munich, Ludwig-Maximilians-University Munich, Munich, Germany.

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October 2019

Combinatorial siRNA Polyplexes for Receptor Targeting.

Authors:

Dian-Jang Lee Ernst Wagner

Methods Mol Biol 2019 ;1974:83-98

Department of Pharmacy, Center for NanoScience, Ludwig-Maximilians-Universität München, Munich, Germany.

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November 2019

Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles.

Authors:

Ines Truebenbach Sarah Kern Dominik M Loy Miriam Höhn Jan Gorges Uli Kazmaier Ernst Wagner

Mol Pharm 2019 06 13;16(6):2405-2417. Epub 2019 May 13.

Pharmaceutical Biotechnology, Center for System-Based Drug Research, and Center for Nanoscience (CeNS) , Ludwig-Maximilians-Universität , 81377 Munich , Germany.

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June 2019

Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines.

Authors:

Philipp Michael Klein Kristina Klinker Wei Zhang Sarah Kern Eva Kessel Ernst Wagner Matthias Barz

Polymers (Basel) 2018 Jun 20;10(6). Epub 2018 Jun 20.

Institute of Organic Chemistry, Johannes Gutenberg University, Duesbergweg 10-14, D-55128 Mainz, Germany.

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June 2018

Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.

Authors:

Lisa Pfitzer Christina Moser Florian Gegenfurtner Anja Arner Florian Foerster Carina Atzberger Themistoklis Zisis Rebekka Kubisch-Dohmen Johanna Busse Rebecca Smith Gyula Timinszky Olga V Kalinina Rolf Müller Ernst Wagner Angelika M Vollmar Stefan Zahler

Cell Death Dis 2019 04 3;10(4):302. Epub 2019 Apr 3.

Department of Pharmacy, Pharmaceutical Biology, Ludwig Maximilian University Munich, Munich, Germany.

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April 2019

Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface.

Authors:

Andreas Zimpel Nader Al Danaf Benjamin Steinborn Jasmin Kuhn Miriam Höhn Tobias Bauer Patrick Hirschle Waldemar Schrimpf Hanna Engelke Ernst Wagner Matthias Barz Don C Lamb Ulrich Lächelt Stefan Wuttke

ACS Nano 2019 04 15;13(4):3884-3895. Epub 2019 Mar 15.

Department of Chemistry and Center for NanoScience (CeNS) , LMU Munich , Butenandtstraße 11 , 81377 Munich , Germany.

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April 2019

Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids.

Authors:

Wolfgang Rödl Alexander Taschauer David Schaffert Ernst Wagner Manfred Ogris

Methods Mol Biol 2019 ;1943:83-99

Laboratory of MacroMolecular Cancer Therapeutics (MMCT), Department of Pharmaceutical Chemistry, Center of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, Vienna, Austria.

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July 2019