Publications by authors named "Ernst Holler"

99Publications

Refractory acute graft-versus-host disease: a new working definition beyond corticosteroid refractoriness.

Blood 2020 Oct;136(17):1903-1906

Department of Medicine I, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood.2020007336DOI Listing
October 2020

Cyclophosphamide for salvage therapy of chronic graft-versus-host disease: a retrospective analysis.

Ann Hematol 2020 Sep 26;99(9):2181-2190. Epub 2020 Jul 26.

Department of Hematology and Oncology, Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00277-020-04193-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419371PMC
September 2020

Successful Treatment of Early Relapsed High-Risk AML After Allogeneic Hematopoietic Stem Cell Transplantation With Biomodulatory Therapy.

Front Oncol 2020 23;10:443. Epub 2020 Apr 23.

Department of Internal Medicine III, Hematology and Internal Oncology, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.3389/fonc.2020.00443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190808PMC
April 2020

Bacterial contamination rates in extracorporeal photopheresis.

Transfusion 2020 Jun 21;60(6):1260-1266. Epub 2020 Apr 21.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg,, Germany.

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http://dx.doi.org/10.1111/trf.15801DOI Listing
June 2020

Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation.

N Engl J Med 2020 02;382(9):822-834

From the Adult Bone Marrow Transplantation Service (J.U.P., M.M., A.G.C., K.A.M., N.K., D.G.B., M.S.-E., N.C.F., A.A.T., R.J.L., L.Y.S.S., G.L.S., C.C., M.S., I.P., B.G., D.M.P., J.N.B., M.-A.P., S.A.G., M.R.M.B.) and the Infectious Disease Service (Y.T., E.F., L.A.A., R.J.W., E.G.P.), Department of Medicine, the Department of Epidemiology and Biostatistics (S.M.D.), the Department of Immunology, Sloan Kettering Institute (A.L.C.G., E.R.L., A.E.S., J.B.S., C.K.S.-T., M.D.D., M.B.S., G.K.A., Y.S., M.R.M.B.), and the Program for Computational and Systems Biology (J.B.X.), Memorial Sloan Kettering Cancer Center, and the Department of Medicine, Weill Cornell Medical College (J.U.P., Y.T., K.A.M., M.D.D., R.J.L., G.L.S., C.C., M.S., I.P., B.G., D.M.P., J.N.B., M.-A.P., S.A.G., M.R.M.B.) - both in New York; Duchossois Family Institute of the University of Chicago, Chicago (E.R.L., E.G.P.); the Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center (A.D.S., M.V.L., A.B., L.B., N.J.C.), the Division of Infectious Diseases, Department of Medicine, Duke University (J.A.M.), and the Duke Office of Clinical Research, Duke University School of Medicine (K.R.) - all in Durham, NC; the Department of Hematology and Oncology, Internal Medicine III, University Medical Center (D.W., E.H.), the Collaborative Research Center Transregio 221 (D.W., A.G., E.H.), and Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg (A.G.) - all in Regensburg, Germany; the Department of Hematology, Hokkaido University Faculty of Medicine (D.H., Y.H., T.T.), and the Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital (K.H., T.T.) - both in Sapporo, Japan; Research Institute Marqués de Valdecilla-IDIVAL (M.S.-E.) and the Department of Hematology, Hospital Universitario Marqués de Valdecilla-IDIVAL, University of Cantabria (L.Y.S.S.), Santander, and Hospital Universitario Puerta de Hierro, Madrid (A.A.T.) - all in Spain; and the Departments of Genomic Medicine and Stem Cell Transplantation Cellular Therapy, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston (R.R.J.).

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http://dx.doi.org/10.1056/NEJMoa1900623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534690PMC
February 2020

IL6-receptor antibody tocilizumab as salvage therapy in severe chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: a retrospective analysis.

Ann Hematol 2020 Apr 21;99(4):847-853. Epub 2020 Feb 21.

Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00277-020-03968-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069928PMC
April 2020

Treosulfan or busulfan plus fludarabine as conditioning treatment before allogeneic haemopoietic stem cell transplantation for older patients with acute myeloid leukaemia or myelodysplastic syndrome (MC-FludT.14/L): a randomised, non-inferiority, phase 3 trial.

Lancet Haematol 2020 Jan 9;7(1):e28-e39. Epub 2019 Oct 9.

Department of Haematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland; Faculty of Medicine, University of Rzeszow, Rzeszow, Poland.

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https://linkinghub.elsevier.com/retrieve/pii/S23523026193015
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http://dx.doi.org/10.1016/S2352-3026(19)30157-7DOI Listing
January 2020

Long-term follow-up of rituximab in treatment of chronic graft-versus-host disease-single center experience.

Ann Hematol 2019 Oct 3;98(10):2399-2405. Epub 2019 Aug 3.

Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00277-019-03768-xDOI Listing
October 2019

Haploidentical CD3 or α/β T-cell depleted HSCT in advanced stage sickle cell disease.

Bone Marrow Transplant 2019 11 14;54(11):1859-1867. Epub 2019 May 14.

Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Franz-Josef-Strauss-Allee 11, University Hospital of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/s41409-019-0550-0DOI Listing
November 2019

Quantification of Fecal Short Chain Fatty Acids by Liquid Chromatography Tandem Mass Spectrometry-Investigation of Pre-Analytic Stability.

Biomolecules 2019 03 28;9(4). Epub 2019 Mar 28.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.

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http://dx.doi.org/10.3390/biom9040121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523859PMC
March 2019

Persistent polyomavirus-associated nephropathy in a patient with GvHD and treatment with the JAK1/2 inhibitor ruxolitinib.

Bone Marrow Transplant 2019 05 22;54(5):762-764. Epub 2018 Oct 22.

Institute of Medical Microbiology and Hygiene, Department of Virology, University of Regensburg, Regensburg, Germany.

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http://www.nature.com/articles/s41409-018-0370-7
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http://dx.doi.org/10.1038/s41409-018-0370-7DOI Listing
May 2019

Editorial: Cellular Therapies: Past, Present and Future.

Front Immunol 2018 30;9:1966. Epub 2018 Aug 30.

Hematological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2018.01966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125389PMC
September 2019

Indoxyl 3-sulfate inhibits maturation and activation of human monocyte-derived dendritic cells.

Immunobiology 2018 02 6;223(2):239-245. Epub 2017 Oct 6.

Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2017.10.014DOI Listing
February 2018

Acute Ocular Graft-versus-Host Disease.

N Engl J Med 2017 Aug;377(7):676

Universitätsklinikum Regensburg, Regensburg, Germany

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http://dx.doi.org/10.1056/NEJMicm1701185DOI Listing
August 2017

Complementary and Alternative Medicine: A Clinical Study in 1,016 Hematology/Oncology Patients.

Oncology 2017 23;93(3):157-163. Epub 2017 Jun 23.

Department of Internal Medicine III, Hematology and Medical Oncology, University Hospital of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1159/000464248DOI Listing
December 2017

Pathophysiology of GvHD and Other HSCT-Related Major Complications.

Front Immunol 2017 20;8:79. Epub 2017 Mar 20.

Department of Internal Medicine III, University Medical Centre , Regensburg , Germany.

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http://dx.doi.org/10.3389/fimmu.2017.00079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357769PMC
March 2017

Fit for cure? Microbiota and GVHD.

Blood 2016 10;128(16):2004-2005

UNIVERSITY OF REGENSBURG.

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http://dx.doi.org/10.1182/blood-2016-08-732156DOI Listing
October 2016

Relation between Acute GVHD and NK Cell Subset Reconstitution Following Allogeneic Stem Cell Transplantation.

Front Immunol 2016 22;7:595. Epub 2016 Dec 22.

Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology (RCI), University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2016.00595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177660PMC
December 2016

Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells.

Int J Mol Sci 2016 Dec 11;17(12). Epub 2016 Dec 11.

Department of Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.

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http://www.mdpi.com/1422-0067/17/12/2081
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http://dx.doi.org/10.3390/ijms17122081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187881PMC
December 2016

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation.

Front Immunol 2016 17;7:507. Epub 2016 Nov 17.

Transplantation Biology, Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School , Hannover , Germany.

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http://dx.doi.org/10.3389/fimmu.2016.00507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112259PMC
November 2016

Granulocytapheresis with modified fluid gelatin versus high-molecular-weight hydroxyethyl starch: a matched-pair analysis.

Transfusion 2017 02 10;57(2):397-403. Epub 2016 Nov 10.

Institute for Clinical Chemistry and Laboratory Medicine, Transfusion Medicine, University Hospital Regensburg, Regensburg.

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http://dx.doi.org/10.1111/trf.13898DOI Listing
February 2017

ABO blood group antigen mismatch has an impact on outcome after allogeneic peripheral blood stem cell transplantation.

Clin Transplant 2016 11 3;30(11):1457-1465. Epub 2016 Oct 3.

Department of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1111/ctr.12840DOI Listing
November 2016

Role of gut flora after bone marrow transplantation.

Nat Microbiol 2016 03 29;1:16036. Epub 2016 Mar 29.

Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nmicrobiol.2016.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027134PMC
March 2016

Technical comparison of four different extracorporeal photopheresis systems.

Transfusion 2016 Oct 26;56(10):2510-2519. Epub 2016 Jul 26.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1111/trf.13728DOI Listing
October 2016

Human beta-defensin-2 and -3 enhance pro-inflammatory cytokine expression induced by TLR ligands via ATP-release in a P2X7R dependent manner.

Immunobiology 2016 11 19;221(11):1259-65. Epub 2016 Jun 19.

Institute of Immunology, University of Regensburg, 93053 Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2016.06.006DOI Listing
November 2016

Risk Factors and Outcome of Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation-Results from a Single-Center Observational Study.

Biol Blood Marrow Transplant 2016 10 22;22(10):1781-1791. Epub 2016 Jun 22.

Department of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2016.06.020DOI Listing
October 2016

Adjusting microbiome profiles for differences in microbial load by spike-in bacteria.

Microbiome 2016 06 21;4(1):28. Epub 2016 Jun 21.

Chair of Statistical Bioinformatics, University of Regensburg, Am BioPark 9, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1186/s40168-016-0175-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915049PMC
June 2016

The lung function score and its components as predictors of overall survival and chronic graft-vs-host disease after allogeneic stem cell transplantation.

Croat Med J 2016 Feb;57(1):16-28

Diana Ditz, Department of Internal Medicine III, University of Regensburg Medical Center, Franz-Josef-Strauss Allee 11, D-93053 Regensburg, Germany,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800331PMC
http://dx.doi.org/10.3325/cmj.2016.57.16DOI Listing
February 2016

A prognostic score for acute graft-versus-host disease based on biomarkers: a multicentre study.

Lancet Haematol 2015 Jan 23;2(1):e21-9. Epub 2014 Dec 23.

Blood & Marrow Transplant Program, University of Michigan, Ann Arbor, MI, USA; The Tisch Cancer Institute, The Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA. Electronic address:

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http://www.thelancet.com/pdfs/journals/lanhae/PIIS2352-3026(
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http://linkinghub.elsevier.com/retrieve/pii/S235230261400035
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http://dx.doi.org/10.1016/S2352-3026(14)00035-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340092PMC
January 2015

Telomere shortening in enterocytes of patients with uncontrolled acute intestinal graft-versus-host disease.

Blood 2015 Nov 20;126(22):2518-21. Epub 2015 Oct 20.

Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen, Germany;

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http://dx.doi.org/10.1182/blood-2015-03-633289DOI Listing
November 2015

Serum REG3alpha and C-Reactive Protein Levels in Crohn's Disease Patients Undergoing Immunoablation and Autologous Hemopoetic Stem Cell Transplantation in the ASTIC Trial.

Digestion 2015 1;92(2):83-9. Epub 2015 Aug 1.

Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1159/000437300DOI Listing
March 2017

Donor Nucleotide-Binding Oligomerization-Containing Protein 2 (NOD2) Single Nucleotide Polymorphism 13 Is Associated with Septic Shock after Allogeneic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2015 Aug 16;21(8):1399-404. Epub 2015 May 16.

Department of Internal Medicine III, Hematology and Oncology, University Hospital, Regensburg, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2015.05.011DOI Listing
August 2015

Biomodulatory metronomic therapy induces PET-negative remission in chemo- and brentuximab-refractory Hodgkin lymphoma.

Br J Haematol 2016 Jan 5;172(2):290-3. Epub 2015 May 5.

Department of Internal Medicine III, Haematology & Oncology, University Hospital of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1111/bjh.13480DOI Listing
January 2016

Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells.

Immunity 2014 Oct 9;41(4):579-91. Epub 2014 Oct 9.

Kimmel Center for Biology and Medicine at the Skirball Institute, New York, NY 10016, USA; Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237219PMC
October 2014

Regression of eosinophil counts after diagnosis of chronic graft-versus-host disease as a potential marker for improved clinical outcome.

Mol Clin Oncol 2014 Jan 25;2(1):81-86. Epub 2013 Sep 25.

Department of Hematology and Oncology, University of Regensburg Medical Center, D-93053 Regensburg, Germany ; ; Feist-Weiller Cancer Center, Department of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA ;

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https://www.spandidos-publications.com/10.3892/mco.2013.192
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http://dx.doi.org/10.3892/mco.2013.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915641PMC
January 2014

Allogeneic transplantation versus chemotherapy as postremission therapy for acute myeloid leukemia: a prospective matched pairs analysis.

J Clin Oncol 2014 Feb 23;32(4):288-96. Epub 2013 Dec 23.

Matthias Stelljes, Utz Krug, Maria C. Sauerland, Achim Heinecke, Sandra Ligges, Tim Sauer, Petra Tschanter, Gabriela B. Thoennissen, Björna Berning, Carsten Müller-Tidow, Wolfgang E. Berdel, and Thomas Büchner, University Hospital of Muenster, Muenster; Dietrich W. Beelen, University Hospital of Essen, Essen; Jan Braess, Krankenhaus Barmherzige Brüder; Albrecht Reichle, Ernst Holler, University of Regensburg, Regensburg; Hans J. Kolb, Wolfgang Hiddeman, University of Munich-Grosshadern, Munich; Rainer Schwerdtfeger, Deutsche Klinik für Diagnostik, Wiesbaden; Renate Arnold, Charité, Universitätsmedizin Berlin, Campus Virchow-Klinikum; Bernhard J. Woermann, German Society of Hematology and Oncology, Berlin; and Christoph Scheid, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1200/JCO.2013.50.5768DOI Listing
February 2014

Entrapment syndrome of multiple nerves in graft-versus-host disease.

Muscle Nerve 2014 Jan 5;49(1):138-42. Epub 2013 Dec 5.

Department of Neurology, St. Josef-Hospital, Ruhr University Bochum, 44791, Bochum, Germany.

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http://dx.doi.org/10.1002/mus.23972DOI Listing
January 2014

Beta-defensins activate macrophages and synergize in pro-inflammatory cytokine expression induced by TLR ligands.

Immunobiology 2013 Jul 29;218(7):1005-11. Epub 2012 Nov 29.

Institute of Immunology, University of Regensburg, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1016/j.imbio.2012.11.007DOI Listing
July 2013

Drug safety evaluation of defibrotide.

Expert Opin Drug Saf 2013 Jan 10;12(1):123-36. Epub 2012 Dec 10.

Dana-Farber Cancer Institute, Medical Oncology, 450 Brookline Avenue, Mayer 232, Boston 02215, USA.

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http://www.tandfonline.com/doi/full/10.1517/14740338.2012.74
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http://dx.doi.org/10.1517/14740338.2012.749855DOI Listing
January 2013