Ernest E Moore

Ernest E Moore

Ernest E Moore

Ernest E Moore

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Eraritjaritjaka revisited: The future of trauma and acute care surgery a symposium of the 2018 North Pacific Surgical Association Annual Meeting.

Am J Surg 2019 May 18;217(5):821-829. Epub 2018 Dec 18.

St Lukes Wood River Medical Center, Ketchum, ID, USA. Electronic address:

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http://dx.doi.org/10.1016/j.amjsurg.2018.12.025DOI Listing
May 2019

The why and how our trauma patients die: A prospective Multicenter Western Trauma Association study.

J Trauma Acute Care Surg 2019 May;86(5):864-870

From the Department of Surgery (R.A.C., L.Z.K., A.S.C., A.J.R.), Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California; Department of Surgery (J.P.M., N.N.), University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, Florida; Department of Surgery (D.E.M., A.H.), McGovern Medical School, University of Texas Health Science Center, Houston; Division of Trauma and Acute Care (M.S.T., V.A.), Methodist Dallas Medical Center, Dallas, Texas; Department of Trauma (J.M.H., K.L.L.), Via Christi Health, Kansas University School of Medicine Wichita Campus, Wichita, Kansas; Division of Trauma (J.M.P., J.L.S.R.), Cooper University Hospital, Camden, New Jersey; Department of Surgery (W.L.B.), Scripps Memorial Hospital La Jolla, La Jolla, California; Department of Surgery (M.S.H.), The Queen's Medical Center, The University of Hawaii, Honolulu, Hawaii; Trauma Service (M.J.S., J.B.), Scripps Mercy Hospital, San Diego; Division of Surgical Critical Care and Trauma (G.R., K.I.), Los Angeles County + University of Southern California Medical Center, Los Angeles, California; Department of Surgery (T.J.S., E.C.), University of Colorado Health, Memorial Hospital, Colorado Springs; Department of Surgery (J.A.D., S.G.), University of Colorado Health North, Medical Center of the Rockies, Loveland, Colorado; Department of Surgery (R.C.M.Jr., E.D.P.), University of Colorado School of Medicine, Aurora, Colorado; Department of Trauma and General Surgery (P.J.O., C.F.D.), Abrazo Medical Group, Abrazo West Campus, Goodyear, Arizona; Department of Surgery (A.M.S., E.E.S.), University of Oklahoma, Oklahoma City, Oklahoma; Division of Trauma and Emergency Acute Care Surgery (M.A.W., S.S.), North Memorial Health Hospital, Robbinsdale, Minnesota; Department of Surgery (D.C.C., J.F.C.), Marshfield Clinic, Marshfield, Wisconsin; Department of Surgery (E.E.M., H.B.M.), Denver Health Medical Center, University of Colorado Denver, Denver, Colorado; Department of Surgery (A.R.P., E.A.E.), Medical University of South Carolina, Charleston, South Carolina; Department of Surgery (M.J.C.), Denver Health Medical Center, Denver; and University of Colorado Medical Center (M.J.C.), Aurora, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000002205DOI Listing
May 2019

Trauma Resuscitation Consideration: Sex Matters.

J Am Coll Surg 2019 May 21;228(5):760-768.e1. Epub 2019 Jan 21.

Department of Surgery, University of Colorado-Denver, Aurora, CO. Electronic address:

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http://dx.doi.org/10.1016/j.jamcollsurg.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487203PMC
May 2019

Redefining postinjury fibrinolysis phenotypes using two viscoelastic assays.

J Trauma Acute Care Surg 2019 Apr;86(4):679-685

From the Department of Surgery (G.R.S., E.E.M., H.B.M., G.R.N., C.C.S., A.B., A.S.), University of Colorado School of Medicine, Aurora, Colorado; Denver Health Medical Center (E.E.M.), Denver, Colorado; Department of Pediatrics (C.C.S.), University of Colorado School of Medicine; Bonfils Blood Center (C.C.S.), Denver, Colorado; and University of Colorado School of Public Health (A.S.), Aurora, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000002165DOI Listing
April 2019

Severe traumatic brain injury is associated with a unique coagulopathy phenotype.

J Trauma Acute Care Surg 2019 Apr;86(4):686-693

From the Department of Surgery (J.M.S., A.B., J.R.C.), University of Colorado Denver; Department of Surgery (E.E.M., M.J.C., A.G., J.C.), Denver Health Medical Center; Department of Pediatrics (C.C.S.), University of Colorado School of Public Health (A.S.), Aurora, CO.

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http://Insights.ovid.com/crossref?an=01586154-900000000-9844
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http://dx.doi.org/10.1097/TA.0000000000002173DOI Listing
April 2019

Essentials of Emergency Transfusion - the Complement to Stop the Bleed.

J Trauma Acute Care Surg 2019 Apr 1. Epub 2019 Apr 1.

Division of Trauma and Surgical Critical Care, Department of Surgery, LAC+USC Medical Center, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1097/TA.0000000000002298DOI Listing
April 2019

The need for dried plasma - a national issue.

Transfusion 2019 Apr;59(S2):1587-1592

US Army Medical Research and Materiel Command, Fort Detrick, Maryland.

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http://dx.doi.org/10.1111/trf.15261DOI Listing
April 2019

TEG Lysis Shutdown Represents Coagulopathy in Bleeding Trauma Patients: Analysis of the PROPPR Cohort.

Shock 2019 Mar 5. Epub 2019 Mar 5.

University of Colorado, Aurora, CO United States.

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http://dx.doi.org/10.1097/SHK.0000000000001341DOI Listing
March 2019

Does Tranexamic Acid Improve Clot Strength in Severely Injured Patients Who Have Elevated Fibrin Degradation Products and Low Fibrinolytic Activity, Measured by Thrombelastography?

J Am Coll Surg 2019 Mar 29. Epub 2019 Mar 29.

School of Public Health, University of Colorado, Denver, CO; Department of Surgery, Ernest E Moore Shock and Trauma Center at Denver Health, Denver, CO.

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http://dx.doi.org/10.1016/j.jamcollsurg.2019.03.015DOI Listing
March 2019

The evolving role of laparoscopic lavage and drainage.

J Trauma Acute Care Surg 2019 Feb;86(2):376

Scripps Memorial Hospital La Jolla La Jolla, California.

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http://dx.doi.org/10.1097/TA.0000000000002145DOI Listing
February 2019

2019 update of the WSES guidelines for management of () infection in surgical patients.

World J Emerg Surg 2019;14. Epub 2019 Feb 28.

74Emergency Surgery Department, Maggiore Parma Hospital, Parma, Italy.

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http://dx.doi.org/10.1186/s13017-019-0228-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394026PMC
February 2019

Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator-dependent manner.

J Trauma Acute Care Surg 2019 Jan;86(1):101-107

From the Koch Institute for Integrative Cancer Research, Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts (C.D.B, Y-W.K, G.S., D.L., M.B.Y.); Division of Acute Care Surgery and Critical Care, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts (C.D.B., M.B.Y.); Department of Surgery, University of Colorado Denver, Denver, Colorado (H.B.M., E.E.M.); Department of Radiology, University of Colorado Denver, Denver, Colorado (M.P.C.); and Department of Surgery, Denver Health Medical Center, Denver, Colorado (E.E.M.).

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http://dx.doi.org/10.1097/TA.0000000000002092DOI Listing
January 2019

Discrepancies between conventional and viscoelastic assays in identifying trauma-induced coagulopathy.

Am J Surg 2019 Jan 23. Epub 2019 Jan 23.

Department of Surgery, Denver Health Medical Center, University of Colorado, 777 Bannock Street, MC 0206, Denver, CO, 80204, United States. Electronic address:

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http://dx.doi.org/10.1016/j.amjsurg.2019.01.014DOI Listing
January 2019

Whole blood mitigates the acute coagulopathy of trauma and avoids the coagulopathy of crystalloid resuscitation.

J Trauma Acute Care Surg 2018 12;85(6):1055-1062

From the Naval Medical Research Unit San Antonio, JBSA-Ft Sam Houston, Texas (F.R.S., L.J.S., A.R.M., J.J.G.); Maine Medical Center, Portland, Maine (F.R.S.); US Army Institute of Surgical Research, JBSA-Ft Sam Houston, Texas (A.P.C.); Department of Surgery, Denver Health Medical Center, Denver, Colorado (H.B.M., E.E.M); and University of Colorado Denver, Aurora, Colorado (H.B.M., E.E.M.).

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http://dx.doi.org/10.1097/TA.0000000000002046DOI Listing
December 2018

Management of colorectal injuries: A Western Trauma Association critical decisions algorithm.

J Trauma Acute Care Surg 2018 Nov;85(5):1016-1020

From the Scripps Memorial Hospital- La Jolla, La Jolla, California (W.L.B.); Denver Health Medical Center/University of Colorado, Denver, Colorado (E.E.M.); R Adams Cowley Shock Trauma Center/University of Maryland, Baltimore, Maryland (D.V.F.); University of Oklahoma Hospital, Oklahoma City, Oklahoma (R.M.A.); University of Tennessee Health Science Center-Memphis, Tennessee (M.A.C.); PeaceHealth Vancouver, Washington (R.K.-J.); Jackson Memorial Hospital/University of Miami, Florida (N.N.); Oregon Health and Science University, Portland, Oregon (S.E.R., M.A.S., K.J.B.); and University of California-Davis Medical Center, Sacramento, California (D.V.S.).

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http://dx.doi.org/10.1097/TA.0000000000001929DOI Listing
November 2018

Evaluation and management of abdominal stab wounds: A Western Trauma Association critical decisions algorithm.

J Trauma Acute Care Surg 2018 Nov;85(5):1007-1015

From the Legacy Emanuel Medical Center (M.J.M.), Portland, Oregon; Dell Medical School (C.V.R.B.), University of Texas at Austin, Austin, Texas; University of California-Davis (D.V.S.), Sacramento, California; University of Michigan (H.A., G.V.), Ann Arbor, Michigan; Oregon Health and Science University (K.B., S.R.), Portland, Oregon; Beth Israel Deaconess Medical Center (C.H.), Boston, Massachusetts; Medical College of Wisconsin (M.D.), Milwaukee, Wisconsin; Denver Health (E.E.M.), Denver, Colorado; Kings County Hospital (B.B.), Brooklyn, New York; and University of Southern California (K.I.), Los Angeles, California.

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http://dx.doi.org/10.1097/TA.0000000000001930DOI Listing
November 2018

Western Trauma Association Critical Decisions in Trauma: Management of renal trauma.

J Trauma Acute Care Surg 2018 Nov;85(5):1021-1025

From the Department of Surgery (C.V.R.B.), Dell Medical School, University of Texas at Austin, Austin, Texas; Department of Surgery (H.B.A.), University of Michigan, Ann Arbor, Michigan; Department of Surgery (K.B., S.R.), Oregon Health and Science University, Portland, Oregon; Department of Surgery (C.J.H.), Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Surgery (M.d.M), Medical College of Wisconsin, Milwaukee, Wisconsin; Department of Surgery (M.M.), Madigan Army Medical Center, Tacoma, Washington; Department of Surgery (E.E.), Denver Health, Denver, Colorado; Department of Surgery (G.V., K.I.), University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1097/TA.0000000000001960DOI Listing
November 2018

Trauma research: Trials and tribulations of a triceratops.

Authors:
Ernest E Moore

J Trauma Acute Care Surg 2018 Nov;85(5):841-850

From the Departments of Surgery (E.E.M.), Ernest E Moore Shock Trauma Center at Denver Health and University of Colorado Denver, Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000002054DOI Listing
November 2018

Citrated kaolin thrombelastography (TEG) thresholds for goal-directed therapy in injured patients receiving massive transfusion.

J Trauma Acute Care Surg 2018 Oct;85(4):734-740

From the Department of Surgery (G.R.S., J.J.S., G.R.N., A.S.), University of Colorado, Aurora, Colorado; Department of Surgery (E.E.M., M.J.C.), Denver Health Medical Center, Denver, Colorado; Department of Pediatrics (C.C.S.), University of Colorado, Aurora, Colorado; Bonfils Blood Center (C.C.S.), Denver, Colorado; University of Colorado School of Public Health (A.S.), University of Colorado, Aurora, Colorado; and Department of Surgery (L.Z.K., A.S.C., R.A.C.), Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California.

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http://Insights.ovid.com/crossref?an=01586154-201810000-0001
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http://dx.doi.org/10.1097/TA.0000000000002037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158094PMC
October 2018

The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections.

World J Emerg Surg 2017 10;12:29. Epub 2017 Jul 10.

Department of Emergency Surgery, Maggiore Hospital, Parma, Italy.

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http://dx.doi.org/10.1186/s13017-017-0141-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504840PMC
September 2018

The defining a model for antimicrobial stewardship-results from an international cross-sectional survey.

Authors:
Massimo Sartelli Francesco M Labricciosa Pamela Barbadoro Leonardo Pagani Luca Ansaloni Adrian J Brink Jean Carlet Ashish Khanna Alain Chichom-Mefire Federico Coccolini Salomone Di Saverio Addison K May Pierluigi Viale Richard R Watkins Luigia Scudeller Lilian M Abbo Fikri M Abu-Zidan Abdulrashid K Adesunkanmi Sara Al-Dahir Majdi N Al-Hasan Halil Alis Carlos Alves André R Araujo da Silva Goran Augustin Miklosh Bala Philip S Barie Marcelo A Beltrán Aneel Bhangu Belefquih Bouchra Stephen M Brecher Miguel A Caínzos Adrian Camacho-Ortiz Marco Catani Sujith J Chandy Asri Che Jusoh Jill R Cherry-Bukowiec Osvaldo Chiara Elif Colak Oliver A Cornely Yunfeng Cui Zaza Demetrashvili Belinda De Simone Jan J De Waele Sameer Dhingra Francesco Di Marzo Agron Dogjani Gereltuya Dorj Laurent Dortet Therese M Duane Mutasim M Elmangory Mushira A Enani Paula Ferrada J Esteban Foianini Mahir Gachabayov Chinmay Gandhi Wagih Mommtaz Ghnnam Helen Giamarellou Georgios Gkiokas Harumi Gomi Tatjana Goranovic Ewen A Griffiths Rosio I Guerra Gronerth Julio C Haidamus Monteiro Timothy C Hardcastle Andreas Hecker Adrien M Hodonou Orestis Ioannidis Arda Isik Katia A Iskandar Hossein S Kafil Souha S Kanj Lewis J Kaplan Garima Kapoor Aleksandar R Karamarkovic Jakub Kenig Ivan Kerschaever Faryal Khamis Vladimir Khokha Ronald Kiguba Hong B Kim Wen-Chien Ko Kaoru Koike Iryna Kozlovska Anand Kumar Leonel Lagunes Rifat Latifi Jae G Lee Young R Lee Ari Leppäniemi Yousheng Li Stephen Y Liang Warren Lowman Gustavo M Machain Marc Maegele Piotr Major Sydney Malama Ramiro Manzano-Nunez Athanasios Marinis Isidro Martinez Casas Sanjay Marwah Emilio Maseda Michael E McFarlane Ziad Memish Dominik Mertz Cristian Mesina Shyam K Mishra Ernest E Moore Akutu Munyika Eleftherios Mylonakis Lena Napolitano Ionut Negoi Milica D Nestorovic David P Nicolau Abdelkarim H Omari Carlos A Ordonez José-Artur Paiva Narayan D Pant Jose G Parreira Michal Pędziwiatr Bruno M Pereira Alfredo Ponce-de-Leon Garyphallia Poulakou Jacobus Preller Céline Pulcini Guntars Pupelis Martha Quiodettis Timothy M Rawson Tarcisio Reis Miran Rems Sandro Rizoli Jason Roberts Nuno Rocha Pereira Jesús Rodríguez-Baño Boris Sakakushev James Sanders Natalia Santos Norio Sato Robert G Sawyer Sandro Scarpelini Loredana Scoccia Nusrat Shafiq Vishalkumar Shelat Costi D Sifri Boonying Siribumrungwong Kjetil Søreide Rodolfo Soto Hamilton P de Souza Peep Talving Ngo Tat Trung Jeffrey M Tessier Mario Tumbarello Jan Ulrych Selman Uranues Harry Van Goor Andras Vereczkei Florian Wagenlehner Yonghong Xiao Kuo-Ching Yuan Agnes Wechsler-Fördös Jean-Ralph Zahar Tanya L Zakrison Brian Zuckerbraun Wietse P Zuidema Fausto Catena

World J Emerg Surg 2017 1;12:34. Epub 2017 Aug 1.

Department of General Surgery, Maggiore Hospital, Parma, Italy.

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http://dx.doi.org/10.1186/s13017-017-0145-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540347PMC
September 2018

Splenic trauma: WSES classification and guidelines for adult and pediatric patients.

World J Emerg Surg 2017 18;12:40. Epub 2017 Aug 18.

General, Emergency and Trauma Surgery, Papa Giovanni XXIII Hospital, P.zza OMS 1, 24128 Bergamo, Italy.

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http://wjes.biomedcentral.com/articles/10.1186/s13017-017-01
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http://dx.doi.org/10.1186/s13017-017-0151-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562999PMC
September 2018

Raising concerns about the Sepsis-3 definitions.

World J Emerg Surg 2018 25;13. Epub 2018 Jan 25.

Department of Emergency Surgery, Parma Maggiore Hospital, Parma, Italy.

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http://dx.doi.org/10.1186/s13017-018-0165-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784683PMC
September 2018

The open abdomen in trauma and non-trauma patients: WSES guidelines.

World J Emerg Surg 2018 2;13. Epub 2018 Feb 2.

Emergency and Trauma Surgery, Parma Maggiore Hospital, Parma, Italy.

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http://dx.doi.org/10.1186/s13017-018-0167-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797335PMC
September 2018

Intrathoracic transmural esophageal perforation (Boerhaave's syndrome): Challenges in management of the delayed presentation.

J Trauma Acute Care Surg 2018 09;85(3):644-645

From the Department of General Surgery (I.I-z., E.E.M.), Denver Health Medical Center, University of Colorado School of Medicine; and St. Joseph Hospital (P.E.), Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001958DOI Listing
September 2018

Trauma and hemorrhagic shock activate molecular association of 5-lipoxygenase and 5-lipoxygenase-Activating protein in lung tissue.

J Surg Res 2018 09 5;229:262-270. Epub 2018 May 5.

School of Medicine, Department of Surgery, Trauma Research Center, University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jss.2018.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020847PMC
September 2018

Coagulopathy in Severe Sepsis: Interconnectivity of Coagulation and the Immune System.

Surg Infect (Larchmt) 2018 Feb/Mar;19(2):208-215. Epub 2018 Jan 18.

2 Department of Surgery, Denver Health Medical Center , Denver, Colorado.

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http://dx.doi.org/10.1089/sur.2017.260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425980PMC
August 2018

Empiric transfusion strategies during life-threatening hemorrhage.

Surgery 2018 08 27;164(2):306-311. Epub 2018 Apr 27.

University of Colorado School of Medicine Department of Surgery, Aurora, CO; University of Colorado School of Public Health, Aurora, CO.

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http://dx.doi.org/10.1016/j.surg.2018.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056322PMC
August 2018

Rotational thromboelastometry thresholds for patients at risk for massive transfusion.

J Surg Res 2018 08 11;228:154-159. Epub 2018 Apr 11.

Department of Surgery, University of Colorado, Aurora, Colorado; University of Colorado School of Public Health, University of Colorado, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jss.2018.03.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039387PMC
August 2018

US National Trends in Violent and Unintentional Injuries, 2000 to 2016.

JAMA Surg 2018 Aug 1. Epub 2018 Aug 1.

Department of Surgery, University of Colorado School of Medicine, Aurora.

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http://dx.doi.org/10.1001/jamasurg.2018.2496DOI Listing
August 2018

Fighting Unarmed Against Firearms.

JAMA Netw Open 2018 Jul 6;1(3):e180845. Epub 2018 Jul 6.

Denver Health Medical Center and University of Colorado, Denver, School of Medicine, Denver.

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http://dx.doi.org/10.1001/jamanetworkopen.2018.0845DOI Listing
July 2018

Goal-directed hemostatic resuscitation for trauma induced coagulopathy: Maintaining homeostasis.

J Trauma Acute Care Surg 2018 06;84(6S Suppl 1):S35-S40

From the Department of Surgery (E.E.M., H.B.M., A.S.), Denver Health Medical Center and University of Colorado Denver; Department of Radiology (M.P.C.), University of Colorado Denver, Denver, Colorado; Department of Plastic Surgery (E.G.), New York University, New York, New York.

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http://dx.doi.org/10.1097/TA.0000000000001797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970013PMC
June 2018

Systemic hyperfibrinolysis after trauma: a pilot study of targeted proteomic analysis of superposed mechanisms in patient plasma.

J Trauma Acute Care Surg 2018 06;84(6):929-938

From the Departments of Surgery (A.B., C.C.S., E.E.M., M.K., A.S., E.G., H.B.M., E.P., B.E.H., P.E., J.C., A.G.), Pediatrics (C.C.S., K.J.), Biochemistry and Molecular Genetics (A.D'A., K.H.), and Radiology (M.P.C.), School of Medicine, University of Colorado Denver, Aurora, CO; Research Laboratory (C.C.S., M.K.), Bonfils Blood Center, Denver, CO; and the Department of Surgery (E.E.M., M.D., A.S., E.G., H.B.M., B.E.H, P.E., J.C., A.G.), Denver Health Medical Center, Denver, CO.

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http://dx.doi.org/10.1097/TA.0000000000001878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970039PMC
June 2018

The focused abdominal sonography for trauma examination can reliably identify patients with significant intra-abdominal hemorrhage in life-threatening pelvic fractures.

J Trauma Acute Care Surg 2018 06;84(6):924-928

From The Department of Surgery (N.T.C., C.C.B., E.E.M., A.E.G., A.E.W., C.J.F., F.M.P.), Denver Health Medical Center and the University of Colorado Denver, Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001838DOI Listing
June 2018

Another mass shooting: Time to ban the assault rifle.

Authors:
Ernest E Moore

J Trauma Acute Care Surg 2018 06;84(6):1036

From the Department of Surgery, Denver Health Medical Center; and University of Colorado Denver, Denver, Colorado.

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http://Insights.ovid.com/crossref?an=01586154-201806000-0002
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http://dx.doi.org/10.1097/TA.0000000000001863DOI Listing
June 2018

Maximizing geographical efficiency: An analysis of the configuration of Colorado's trauma system.

J Trauma Acute Care Surg 2018 05;84(5):762-770

From the Division of Acute Care Surgery, Department of Surgery (J.O.J.), University of Alabama at Birmingham, Birmingham, Alabama; Health Services Research Unit (J.O.J.), University of Aberdeen, Aberdeen, United Kingdom; Department of Surgery (E.E.M.), University of Colorado, Denver; Department of Surgery (E.E.M.), Denver Health Medical Center, Denver, Colorado; Department of Computing (H.W.), University of Surrey, Guildford, United Kingdom; Department of Surgery (J.J.M.), R Adams Cowley Shock Trauma Center, Baltimore, Maryland; Department of Surgery (J.D.H.), Medical School, University of Aberdeen, Aberdeen, United Kingdom; Health Services Research Unit (M.K.C.), University of Aberdeen, Aberdeen, United Kingdom; and Schools of Public Health and Medicine (A.S.), University of Colorado, Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001802DOI Listing
May 2018

Preperitoneal pelvic packing is effective for hemorrhage control in open pelvic fractures.

Am J Surg 2018 Apr 22;215(4):675-677. Epub 2017 Nov 22.

Department of Surgery, Denver Health Medical Center and the University of Colorado Denver, Denver, CO, United States.

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http://dx.doi.org/10.1016/j.amjsurg.2017.11.024DOI Listing
April 2018

Pediatric appendicitis: Is referral to a regional pediatric center necessary?

J Trauma Acute Care Surg 2018 04;84(4):636-641

From the Laboratory for Fetal and Regenerative Biology, Department of Surgery (M.M.H.), University of Colorado Denver, Anschutz Medical Campus and Children's Hospital Colorado, Aurora, Colorado; Department of General Surgery (M.M.H., C.C.B., E.E.M., B.B.), Denver Health Medical Center, Denver, Colorado; Department of Pediatric Surgery (S.N.A., L.R.S.H., D.A.P., D.B.), Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado; Department of Emergency Medicine (G.E.S.), Denver Health Medical Center, Denver, Colorado; and University of Colorado School of Medicine (A.S.), Aurora, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001787DOI Listing
April 2018

All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients.

J Trauma Acute Care Surg 2018 03;84(3):537-541

From the Department of Biochemistry and Molecular Genetics (J.A.R., M.J.W., K.C.H., A.D.), University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado; Denver Health Hospital - (E.E.M., A.G., J.C.), Denver, Colorado; Department of Surgery (A.L.S., H.B.M., M.F., G.N., A.B.), University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado; Naval Medical Research Unit San Antonio (L.J.S., F.R.S.), JBSA-Ft. Sam Houston, Texas; Department of Paediatrics (C.C.S.), University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado; and Bonfils Blood Center (C.C.S.), Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820217PMC
March 2018

Use of Uncrossmatched Erythrocytes in Emergency Bleeding Situations.

Anesthesiology 2018 Mar;128(3):650-656

From the Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania (M.H.Y.); the Department of Anesthesiology, University of Pittsburgh, Pennsylvania (J.H.W.); and the Department of Pediatrics, Division of Critical Care Medicine, Washington University in St. Louis, St. Louis, Missouri (P.C.S.). U.S. Army Institute of Surgical Research, San Antonio, Texas U.S. Armed Services Blood Program, Washington, DC AABB, Bethesda, Maryland Department of Surgery, Division of Trauma and Emergency Surgery, University of Texas San Antonio, San Antonio, Texas AABB, Bethesda, Maryland Department of Surgery, University of Colorado, Denver, Colorado Johns Hopkins University School of Medicine, Baltimore, Maryland Magen David Adom National Blood Services, Ramat Gan, Israel Department of Laboratory Medicine, Boston Children's Hospital, Boston, Massachusetts Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota Department of Emergency Medicine, Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, Michigan.

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March 2018

The FAST Exam Can Reliably Identify Patients with Significant Intraabdominal Hemorrhage in Life Threatening Pelvic Fractures.

J Trauma Acute Care Surg 2018 Feb 14. Epub 2018 Feb 14.

From The Department of Surgery, Denver Health Medical Center and the University of Colorado Denver, Denver, CO.

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http://dx.doi.org/10.1097/TA.0000000000001838DOI Listing
February 2018

The pitfalls of resuscitative endovascular balloon occlusion of the aorta: Risk factors and mitigation strategies.

J Trauma Acute Care Surg 2018 01;84(1):192-202

From the University of California Davis (A.J.D., R.M.R., J.J.D.), Sacramento, California; Kirov Military Medical Academy (V.A.R.), Saint-Petersburg, Russian Federation; R Adams Cowley Shock Trauma Medical Center (M.L.B.), Baltimore, Maryland; University of Texas Health Science Center (L.J.M.), Houston, Texas; Foothills Medical Centre (C.B.), University of Calgary, Calgary, Alberta, Canada; Harborview Medical Center (E.B.), University of Washington, Seattle, Washington; Denver Health (E.E.M.), Denver, Colorado; Uniformed Services (T.E.R.), University of the Health Sciences, Bethesda, Maryland.

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January 2018

Tranexamic acid is associated with increased mortality in patients with physiological fibrinolysis.

J Surg Res 2017 12 8;220:438-443. Epub 2017 May 8.

Department of Surgery, University of Colorado Denver, Aurora, Colorado; University of Colorado School of Public Health, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jss.2017.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677580PMC
December 2017

Early Definitive Fracture Fixation is Safely Performed in the Presence of an Open Abdomen in Multiply Injured Patients.

J Orthop Trauma 2017 Dec;31(12):624-630

Department of Orthopaedics, Denver Health Medical Center, University of Colorado, School of Medicine, Denver, CO.

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http://dx.doi.org/10.1097/BOT.0000000000000959DOI Listing
December 2017

Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin.

J Trauma Acute Care Surg 2017 12;83(6):1053-1061

From the Koch Institute for Integrative Cancer Research (C.D.B.), Massachusetts Institute of Technology, Cambridge, Massachusetts; Department of Surgery (C.D.B.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; Departments of Surgery (H.B.M., A.B., E.E.M.) and Pediatrics (C.C.S.), University of Colorado Denver, Denver, Colorado; Bonfils Blood Center (C.C.S.), Denver, Colorado; Department of Surgery (E.E.M.), Denver Health Medical Center, Denver, Colorado; Koch Institute (M.B.Y.), Massachusetts Institute of Technology, Cambridge, Massachusetts; and Division of Acute Care Surgery and Critical Care, Department of Surgery (M.B.Y.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1097/TA.0000000000001685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767103PMC
December 2017

The hypercoagulability paradox of chronic kidney disease: The role of fibrinogen.

Am J Surg 2017 Dec 18;214(6):1215-1218. Epub 2017 Sep 18.

Department of Surgery, University of Colorado Denver, Aurora, CO, USA; School of Public Health, University of Colorado Denver, Aurora, CO, USA.

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http://dx.doi.org/10.1016/j.amjsurg.2017.08.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693753PMC
December 2017

Platelet adenosine diphosphate receptor inhibition provides no advantage in predicting need for platelet transfusion or massive transfusion.

Surgery 2017 12 28;162(6):1286-1294. Epub 2017 Sep 28.

Department of Surgery, University of Colorado School of Medicine, Denver, CO; Department of Health Systems, Management & Policy, University of Colorado School of Public Health, Denver, CO.

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http://dx.doi.org/10.1016/j.surg.2017.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694384PMC
December 2017

Targeting resuscitation to normalization of coagulating status: Hyper and hypocoagulability after severe injury are both associated with increased mortality.

Am J Surg 2017 Dec 18;214(6):1041-1045. Epub 2017 Sep 18.

Department of Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston/Red Duke Trauma Institute at Memorial Hermann, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.amjsurg.2017.08.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693672PMC
December 2017

Discussion of: "The hypercoagulability paradox of chronic kidney disease: The role of fibrinogen".

Am J Surg 2017 12 5;214(6):1219. Epub 2017 Oct 5.

Department of Surgery, University of Colorado Denver, Aurora, CO, USA; School of Public Health, University of Colorado Denver, Aurora, CO, USA.

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http://dx.doi.org/10.1016/j.amjsurg.2017.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248910PMC
December 2017

Discussion of: "Targeting resuscitation to normalization of coagulating status: Hyper and hypocoagulability after severe injury are both associated with increased mortality".

Am J Surg 2017 12 5;214(6):1046-1047. Epub 2017 Oct 5.

Department of Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston/Red Duke Trauma Institute at Memorial Hermann, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.amjsurg.2017.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693758PMC
December 2017

Current trends in the management of hemodynamically unstable pelvic ring injuries.

Curr Opin Crit Care 2017 Dec;23(6):511-519

aDepartment of Orthopaedics and Neurosurgery, School of Medicine, Denver Health Medical Center, University of Colorado, DenverbRocky Vista University College of Osteopathic Medicine, ParkercDepartment of Surgery, School of Medicine, Denver Health Medical Center, University of Colorado, Denver, Colorado, USA.

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http://dx.doi.org/10.1097/MCC.0000000000000454DOI Listing
December 2017

Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator.

J Trauma Acute Care Surg 2017 12;83(6):1014-1022

From the Department of Surgery (H.B.M., E.E.M., B.R.H., M.D., G.R.S., G.R.N., P.J.L., A.B., C.S., A.S., K.C.H.), University of Colorado; Denver Health Medical Center (E.E.M., A.G., J.C.); and University of Colorado School of Public Health (A.S.), Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726780PMC
December 2017

The 10 anniversary of patient safety in surgery.

Patient Saf Surg 2017 14;11:27. Epub 2017 Dec 14.

Department of Surgery and Transplantation, University Hospital Zurich, CH-8091 Zurich, Switzerland.

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http://dx.doi.org/10.1186/s13037-017-0145-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731067PMC
December 2017

Shootout at the O.K. Corral-History Revisited.

J Trauma Acute Care Surg 2017 11;83(5):981-983

From the Division of Trauma, Burns, Surgical Critical Care, and Emergency General Surgery, Department of Surgery (G.A.V.), University of Arizona, Tucson, Arizona; Division of Trauma, Surgical Critical Care, and Emergency General Surgery, Department of Surgery (Z.M.B.), University of Nebraska, Omaha, Nebraska; University of Southern California (J.R.), Pasadena, CA; Grady Memorial Hospital (P.M.R.), Atlanta, Georgia; and Division of Trauma and Acute Care Surgery, Department of Surgery (E.E.M.), University of Colorado, Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001632DOI Listing
November 2017

Intrathoracic transmural esophageal perforation (Boerhaave syndrome): Challenges in management of the delayed presentation.

J Trauma Acute Care Surg 2017 11;83(5):987-989

From the Denver Health Medical Center (I.I.-Z., E.E.M.), University of Colorado School of Medicine, Department of General Surgery, Aurora, Colorado; and St. Joseph Hospital (P.E.), Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001662DOI Listing
November 2017

14-Day thawed plasma retains clot enhancing properties and inhibits tPA-induced fibrinolysis.

J Surg Res 2017 11 12;219:145-150. Epub 2017 May 12.

Department of Pediatrics, University of Colorado, Aurora, Colorado; Bonfils Blood Center, Denver, Colorado.

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http://dx.doi.org/10.1016/j.jss.2017.05.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675137PMC
November 2017

Hemorrhagic shock and tissue injury drive distinct plasma metabolome derangements in swine.

J Trauma Acute Care Surg 2017 10;83(4):635-642

From the Department of Anesthesiology (N.C.), Department of Surgery (G.R.N., E.G., E.P., C.C.S., M.F., A.B., H.B.M.), University of Colorado Denver; Denver Health Hospital (E.E.M.); 4Department of Biochemistry and Molecular Genetics (J.A.R., T.N., T.N., M.J.W., A.D.A.), University of Colorado Denver; Bonfils Blood Center (C.C.S., K.H.,); and Department of Pediatrics (C.C.S.), University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608631PMC
October 2017

The Pitfalls of REBOA: Risk Factors and Mitigation Strategies.

J Trauma Acute Care Surg 2017 Oct 4. Epub 2017 Oct 4.

1University of California Davis, Sacramento, California, USA 2Kirov Military Medical Academy, Saint-Petersburg, Russian Federation 3R Adams Cowley Shock Trauma Medical Center, Baltimore, Maryland, USA 4University of Texas Health Science Center, Houston, Texas, USA 5Foothills Medical Centre, University of Calgary, Canada 6Harborview Medical Center, University of Washington, Seattle, Washington, USA 7Denver Health, Denver, Colorado, USA 8Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.

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October 2017

The role of NIGMS P50 sponsored team science in our understanding of multiple organ failure.

J Trauma Acute Care Surg 2017 09;83(3):520-531

From the Acute Care Surgery division (F.A.M., L.L.M.), University of Florida, Gainesville, Florida; Department of Surgery (E.E.M., A.B.), Denver Health, University of Colorado, Denver, Colorado; and Department of Surgery (T.R.B., Y.V.), University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/TA.0000000000001587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573617PMC
September 2017

Plasma succinate is a predictor of mortality in critically injured patients.

J Trauma Acute Care Surg 2017 09;83(3):491-495

From the Department of Biochemistry and Molecular Genetics (A.D.A., J.A.R., M.J.W., K.C.H.), University of Colorado Denver-Anschutz Medical Campus; Denver Health Hospital (H.B.M., E.E.M., A.G., J.C.), Denver; Department of Surgery (E.E.M., A.B.), Department of Pediatrics (C.C.S.), University of Colorado Denver-Anschutz Medical Campus, Aurora; and Bonfils Blood Center (C.C.S.), Denver, CO.

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http://dx.doi.org/10.1097/TA.0000000000001565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573618PMC
September 2017

The role of pre-reduction MRI in the management of complex cervical spine fracture-dislocations: an ongoing controversy?

Patient Saf Surg 2017 8;11:23. Epub 2017 Sep 8.

Department of Orthopaedics, University of Colorado, School of Medicine and Denver Health Medical Center, 777 Bannock Street, Denver, CO 80204 USA.

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http://dx.doi.org/10.1186/s13037-017-0139-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591568PMC
September 2017

Viscoelastic Tissue Plasminogen Activator Challenge Predicts Massive Transfusion in 15 Minutes.

J Am Coll Surg 2017 Jul 15;225(1):138-147. Epub 2017 May 15.

University of Colorado School of Medicine, Aurora, CO; University of Colorado School of Public Health, Aurora, CO.

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http://dx.doi.org/10.1016/j.jamcollsurg.2017.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527680PMC
July 2017

Hemoglobin-based oxygen carriers promote systemic hyperfibrinolysis that is both dependent and independent of plasmin.

J Surg Res 2017 06 25;213:166-170. Epub 2015 Apr 25.

Department of Surgery-Trauma Research Center, University of Colorado, Denver, Colorado; Bonfils Blood Center, Denver, Colorado.

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http://dx.doi.org/10.1016/j.jss.2015.04.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467451PMC
June 2017

A Salute to the Editor: Basil A. Pruitt, Jr., M.D. 1995-2011.

Authors:
Ernest E Moore

J Trauma Acute Care Surg 2017 Jun 20. Epub 2017 Jun 20.

Presented at the Basil A. Pruitt, Jr., M.D. Feschrift, San Antonio, Texas, April 2016.

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http://dx.doi.org/10.1097/TA.0000000000001628DOI Listing
June 2017

What is the current role of laparoscopic lavage in perforated diverticulitis?

J Trauma Acute Care Surg 2017 04;82(4):810-813

From the Queen's Medical Center (W.L.B.), Honolulu, Hawaii; Department of Surgery (F.A.M.), University of Florida, Gainesville, Florida; and Department of Surgery (E.E.M.), Denver Health Medical Center, Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360487PMC
April 2017

Tissue injury suppresses fibrinolysis after hemorrhagic shock in nonhuman primates (rhesus macaque).

J Trauma Acute Care Surg 2017 04;82(4):750-757

From the Naval Medical Research Unit San Antonio (A.R.M., F.R.S.), Sam, Houston, Texas; Department of Surgery (H.B.M., E.E.M.), Denver Health Medical Center, Denver, Colorado; Department of Surgery, University of Colorado Denver (E.E.M.), Aurora, Colorado; and US Army Institute of Surgical Research (A.P.C., M.A.M.), Sam Houston, Texas.

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http://dx.doi.org/10.1097/TA.0000000000001379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767102PMC
April 2017

The need for a National Trauma Institute within the National Institutes of Health.

J Trauma Acute Care Surg 2017 03;82(3):649

Department of Surgery, University of Colorado, Denver, Colorado Department of Surgery, University of Washington, Seattle, Washington Department of Surgery, University of Colorado, Denver, Colorado Department of Surgery, Denver Health Medical Center, Denver, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000001367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526711PMC
March 2017

Nonhuman primate model of polytraumatic hemorrhagic shock recapitulates early platelet dysfunction observed following severe injury in humans.

J Trauma Acute Care Surg 2017 03;82(3):461-469

From the Naval Medical Research Unit San Antonio (L.J.S., J.J.G., F.R.S.), JBSA-Fort Sam Houston, Texas; Department of Surgery (H.B.M., E.E.M.), Denver Health Medical Center, Denver, Colorado; University of Colorado Denver (H.B.M., E.E.M.), Aurora, Colorado; and US Army Institute of Surgical Research (A.P.C.), JBSA-Fort Sam Houston, Texas.

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http://dx.doi.org/10.1097/TA.0000000000001343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688844PMC
March 2017