Publications by authors named "Ermia Farokhi"

4 Publications

  • Page 1 of 1

Designing a Logistic Regression Model for a Dataset to Predict Diabetic Foot Ulcer in Diabetic Patients: High-Density Lipoprotein (HDL) Cholesterol Was the Negative Predictor.

J Diabetes Res 2021 16;2021:5521493. Epub 2021 Mar 16.

Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.

Objectives: Although the risk factors for diabetic neuropathy and diabetic foot ulcer have been detected, there was no practical modeling for their prediction. We aimed to design a logistic regression model on an Iranian dataset to predict the probability of experiencing diabetic foot ulcers up to a considered age in diabetic patients.

Methods: The present study was a statistical modeling on a previously published dataset. The covariates were sex, age, body mass index (BMI), fasting blood sugar (FBS), hemoglobin A1C (HbA1C), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), insulin dependency, and statin use. The final model of logistic regression was designed through a manual stepwise method. To study the performance of the model, an area under receiver operating characteristic (AUC) curve was reported. A scoring system was defined according to the coefficients to be used in logistic function for calculation of the probability.

Results: The pretest probability for the outcome was 30.83%. The final model consisted of age (1 = 0.133), BMI (2 = 0.194), FBS (3 = 0.011), HDL (4 = -0.118), and insulin dependency (5 = 0.986) ( < 0.1). The performance of the model was definitely acceptable (AUC = 0.914).

Conclusion: This model can be used clinically for consulting the patients. The only negative predictor of the risk is HDL cholesterol. Keeping the HDL level more than 50 (mg/dl) is strongly suggested. Logistic regression modeling is a simple and practical method to be used in the clinic.
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http://dx.doi.org/10.1155/2021/5521493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994070PMC
March 2021

Recurrence of fatty liver disease following liver transplantation for NAFLD-related cirrhosis: Current status and challenges.

Caspian J Intern Med 2020 ;11(4):346-354

Research Center for Cancer Screening and Epidemiology, AJA University of Medical Sciences, Tehran, Iran.

Non-alcoholic fatty liver disease (NAFLD) is emerging as a major health problem worldwide. NAFLD is a continuum of disease ranging from mild liver steatosis to severe steatohepatitis, which will ultimately lead to end-stage liver disease with high morbidity and mortality rates. This disorder is considered as a silent liver disease. The metabolic syndrome and its components are accounted as the major risk factors for the progression of NAFLD to NASH and cirrhosis. Liver transplantation is considered as an appropriate treatment for the end-stage disease. For the last two decades, NASH has been the most common reason for liver transplantation, especially in the developed countries; however, the outcome of post-transplantation in these patients is of a great concern. The recurrent NASH and NAFLD seem to be the usual issues in LT. Steatosis appears in more than 80% of LTs; however, re-transplantation caused by steatohepatitis is rare. Recently, several risk factors of the recurrent NAFLD, including age, donor steatosis, metabolic syndrome, and immunosuppressant agents, have been introduced. Among the metabolic syndrome components, obesity seriously has negative effects on the outcomes of post-liver transplantation in patients. Unfortunately, there is no standard medicine to prevent or treat the recurrent NAFLD; however, it seems that weight loss and lifestyle modification play critical roles in controlling or inhibiting the recurrent NAFLD or NASH.
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http://dx.doi.org/10.22088/cjim.11.4.346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911758PMC
January 2020

Pulmonary Complications in Candidates for Liver Transplantation.

Middle East J Dig Dis 2020 Jul;12(3):145-153

Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.

The liver plays a pivotal role in maintaining the homeostasis of various organ systems. Also, end-stage liver disease and its complications are major causes of morbidity and mortality among adults. Individuals who develop a chronic liver disease are at increased risk of progression to multi-organ dysfunction, including the pulmonary system. The clinical complications of pulmonary problems related to the presence of liver disease range from mild (such as hypoxemia) to life-threatening diseases (such as portopulmonary hypertension and hepatopulmonary syndrome). Herein, the major pulmonary complications related to liver cirrhosis and considerations for performing liver transplantation are reviewed.
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http://dx.doi.org/10.34172/mejdd.2020.176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548088PMC
July 2020

COVID-19 and telemedicine: Immediate action required for maintaining healthcare providers well-being.

J Clin Virol 2020 05 4;126:104345. Epub 2020 Apr 4.

Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran; Research Center for Immunodefiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

The well-being of the health care workforce is the cornerstone of every well-functioning health system. As a result of the pandemic, medical healthcare providers are under an enormous amount of workload pressure along with increased total health expenditures. The overwhelming burden of COVID-19 illness could lead to caregiver burnout. Direct-to-consumer telemedicine can enable patients to connect with their healthcare provider at a distance. This virtual platform could be used by smartphones or webcam-enabled computers and allows physicians to effectively screen patients with early signs of COVID-19 before they reach to hospital.
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http://dx.doi.org/10.1016/j.jcv.2020.104345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129277PMC
May 2020