Publications by authors named "Erin E Mulvihill"

38Publications

Size-adjusted aortic valve area: refining the definition of severe aortic stenosis.

Eur Heart J Cardiovasc Imaging 2020 Nov 28. Epub 2020 Nov 28.

Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada.

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http://dx.doi.org/10.1093/ehjci/jeaa295DOI Listing
November 2020

Understanding Dietary Intervention-Mediated Epigenetic Modifications in Metabolic Diseases.

Front Genet 2020 15;11:590369. Epub 2020 Oct 15.

University of Ottawa Heart Institute, Ottawa, ON, Canada.

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http://dx.doi.org/10.3389/fgene.2020.590369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593700PMC
October 2020

Islet Health, Hormone Secretion, and Insulin Responsivity with Low-Carbohydrate Feeding in Diabetes.

Metabolites 2020 Nov 11;10(11). Epub 2020 Nov 11.

Energy Substrate Laboratory, The University of Ottawa Heart Institute, 40 Ruskin Street, H-3229A, Ottawa, ON KIY 4W7, Canada.

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http://dx.doi.org/10.3390/metabo10110455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697690PMC
November 2020

Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice.

J Lipid Res 2020 Dec 25;61(12):1697-1706. Epub 2020 Sep 25.

Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada

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http://dx.doi.org/10.1194/jlr.RA120001040DOI Listing
December 2020

The gut hormone receptor GIPR links energy availability to the control of hematopoiesis.

Mol Metab 2020 09 7;39:101008. Epub 2020 May 7.

Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, ON, M5G 1X5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2020.101008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283165PMC
September 2020

Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.

Cell Metab 2020 May 9;31(5):909-919.e8. Epub 2020 Apr 9.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada; Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2020.03.017DOI Listing
May 2020

Dipeptidyl Peptidase-4 at the Interface Between Inflammation and Metabolism.

Clin Med Insights Endocrinol Diabetes 2020 20;13:1179551420912972. Epub 2020 Mar 20.

University of Ottawa Heart Institute, Ottawa, ON, Canada.

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http://dx.doi.org/10.1177/1179551420912972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088130PMC
March 2020

l-Citrulline supplementation improves glucose and exercise tolerance in obese male mice.

Exp Physiol 2020 02 15;105(2):270-281. Epub 2020 Jan 15.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1113/EP088109DOI Listing
February 2020

Physiological roles of the GIP receptor in murine brown adipose tissue.

Mol Metab 2019 10 10;28:14-25. Epub 2019 Aug 10.

Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822254PMC
October 2019

Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action.

Cell Rep 2019 06;27(11):3371-3384.e3

Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Medicine, University of Toronto, Toronto, ON M5S 2J7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.05.055DOI Listing
June 2019

The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice.

Mol Metab 2019 04 5;22:37-48. Epub 2019 Feb 5.

Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437632PMC
April 2019

Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition.

Cell Metab 2019 02 1;29(2):320-334.e5. Epub 2018 Nov 1.

Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, LTRI, 600 University Avenue TCP5-1004, Toronto, ON M5G 1X5, Canada; Department of Medicine, University of Toronto, Toronto, ON M5S 2J7, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183063
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http://dx.doi.org/10.1016/j.cmet.2018.10.001DOI Listing
February 2019

GLP-1 Receptor Expression Within the Human Heart.

Endocrinology 2018 04;159(4):1570-1584

Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1210/en.2018-00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939638PMC
April 2018

Regulation of intestinal lipid and lipoprotein metabolism by the proglucagon-derived peptides glucagon like peptide 1 and glucagon like peptide 2.

Authors:
Erin E Mulvihill

Curr Opin Lipidol 2018 04;29(2):95-103

University of Ottawa Heart Institute, University of Ottawa, Department of Biochemistry, Microbiology and Immunology, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1097/MOL.0000000000000495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882252PMC
April 2018

Dipeptidyl peptidase inhibitor therapy in type 2 diabetes: Control of the incretin axis and regulation of postprandial glucose and lipid metabolism.

Authors:
Erin E Mulvihill

Peptides 2018 02;100:158-164

University of Ottawa Heart Institute, University of Ottawa, Department of Biochemistry, Microbiology and Immunology, 40 Ruskin Street, Ottawa, ON, K1Y4W7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2017.11.023DOI Listing
February 2018

Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction.

Cell Metab 2018 02 21;27(2):450-460.e6. Epub 2017 Dec 21.

Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON M5G 1X5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.11.003DOI Listing
February 2018

The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice.

Mol Metab 2017 11 1;6(11):1339-1349. Epub 2017 Sep 1.

Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778173060
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http://dx.doi.org/10.1016/j.molmet.2017.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681270PMC
November 2017

Cellular Sites and Mechanisms Linking Reduction of Dipeptidyl Peptidase-4 Activity to Control of Incretin Hormone Action and Glucose Homeostasis.

Cell Metab 2017 01 10;25(1):152-165. Epub 2016 Nov 10.

Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Medicine, University of Toronto, Toronto, ON M5S 2J7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.10.007DOI Listing
January 2017

Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis.

Annu Rev Nutr 2016 07 4;36:275-99. Epub 2016 May 4.

Department of Biochemistry, University of Western Ontario, London, ON, Canada N6A 5B7; email: ;

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http://dx.doi.org/10.1146/annurev-nutr-071715-050718DOI Listing
July 2016

Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat-Fed Diabetic Mice.

Diabetes 2016 Mar 15;65(3):742-54. Epub 2015 Dec 15.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.2337/db15-1224DOI Listing
March 2016

Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21.

Endocrinology 2015 Jun 16;156(6):2087-102. Epub 2015 Mar 16.

Department of Vascular Biology (J.M.A., E.E.M., A.C.B., B.G.S., D.E.T., S.S.C., C.G.S., M.W.H.) and Imaging Research Laboratories (M.D.), Robarts Research Institute, London, Ontario, Canada N6A 5B7; Children's Health Research Institute and Departments of Paediatrics, Physiology and Pharmacology, and Oncology (C.L.P.); Departments of Biochemistry (J.M.A., E.E.M., A.C.B., S.S.C., M.W.H.), Medical Biophysics (M.D.) and Medicine (D.E.T., C.G.S., M.W.H.), The University of Western Ontario, London, Ontario, Canada N6A 5B7; and Lilly Research Laboratories (A.C.A., A.K.), Division of Eli Lilly and Company, Indianapolis, Indiana 46285.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2014-2003DOI Listing
June 2015

Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors.

Endocr Rev 2014 Dec 12;35(6):992-1019. Epub 2014 Sep 12.

Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, University of Toronto, Toronto, ON M5G 1X5, Canada.

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https://academic.oup.com/edrv/article-lookup/doi/10.1210/er.
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http://dx.doi.org/10.1210/er.2014-1035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108477PMC
December 2014

Citrus flavonoids and lipid metabolism.

Curr Opin Lipidol 2013 Feb;24(1):34-40

Department of Biochemistry, Department of Medicine, The University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1097/MOL.0b013e32835c07fdDOI Listing
February 2013

Citrus flavonoids and the prevention of atherosclerosis.

Cardiovasc Hematol Disord Drug Targets 2012 Dec;12(2):84-91

Vascular Biology, Robarts Research Institute, London, Ontario, Canada.

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http://dx.doi.org/10.2174/1871529x11202020084DOI Listing
December 2012

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation.

PPAR Res 2012 30;2012:857142. Epub 2012 May 30.

Vascular Biology Group, Robarts Research Institute, 100 Perth Drive, London, ON, Canada N6A 5K8.

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http://dx.doi.org/10.1155/2012/857142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369495PMC
August 2012

Antiatherogenic properties of flavonoids: implications for cardiovascular health.

Can J Cardiol 2010 Mar;26 Suppl A:17A-21A

Vascular Biology, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1016/s0828-282x(10)71056-4DOI Listing
March 2010

Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor.

J Lipid Res 2008 Oct 27;49(10):2218-29. Epub 2008 Jun 27.

Robarts Research Institute, Departments of Medicine and Biochemistry, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1194/jlr.M800297-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533411PMC
October 2008