Publications

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.
Immunity 2016 Oct;45(4):817-830
Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany. Electronic address:

Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells.
Immunity 2016 Jul 5;45(1):60-73. Epub 2016 Jul 5.
Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Nat Immunol 2016 Jun 4;17(6):656-65. Epub 2016 Apr 4.
Jill Roberts Institute for Research in Inflammatory Bowel Disease, Joan and Sanford I. Weill Department of Medicine, Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, New York, USA.

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites.
Cell 2016 Jun 2;165(7):1708-20. Epub 2016 Jun 2.
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:


Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function.
Immunity 2016 Jun;44(6):1325-36
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany. Electronic address:

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Cell 2015 Sep 27;162(6):1229-41. Epub 2015 Aug 27.
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA. Electronic address:

The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.
Immunity 2015 Jan 2;42(1):41-54. Epub 2015 Jan 2.
Goodman Cancer Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada; Department of Physiology, McGill University, Montreal, QC, H3G 1Y6, Canada. Electronic address:

Autophagy is essential for effector CD8(+) T cell survival and memory formation.
Nat Immunol 2014 Dec 2;15(12):1152-61. Epub 2014 Nov 2.
Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.





CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability.
Proc Natl Acad Sci U S A 2013 Aug 12;110(35):14336-41. Epub 2013 Aug 12.
Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.



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