Publications by authors named "Erik Portelius"

132 Publications

Brevican and Neurocan Peptides as Potential Cerebrospinal Fluid Biomarkers for Differentiation Between Vascular Dementia and Alzheimer's Disease.

J Alzheimers Dis 2021 ;79(2):729-741

Department of Psychiatry and Neurochemistry,Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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January 2021

Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury.

Clin Chim Acta 2021 Jan 2;512:74-83. Epub 2020 Dec 2.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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January 2021

Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury.

Sci Rep 2020 10 22;10(1):18075. Epub 2020 Oct 22.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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October 2020

Cerebrospinal Fluid Concentrations of Extracellular Matrix Proteins in Alzheimer's Disease.

J Alzheimers Dis 2019 ;69(4):1213-1220

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Sweden.

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September 2020

Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain.

Brain 2019 05;142(5):1441-1457

Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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May 2019

Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain injury.

Clin Chem Lab Med 2019 Sep;57(10):1565-1573

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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September 2019

Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments.

PLoS One 2019 28;14(2):e0212815. Epub 2019 Feb 28.

Department of Neurology, University of Minnesota, Minneapolis, Minnesota, United States of America.

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December 2019

A distinct brain beta amyloid signature in cerebral amyloid angiopathy compared to Alzheimer's disease.

Neurosci Lett 2019 05 23;701:125-131. Epub 2019 Feb 23.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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May 2019

Neurofilament changes in serum and cerebrospinal fluid after acute ischemic stroke.

Neurosci Lett 2019 04 29;698:58-63. Epub 2018 Dec 29.

Department of Psychiatry & Neurochemistry, University of Gothenburg, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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April 2019

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

Acta Neuropathol 2019 02 13;137(2):279-296. Epub 2018 Dec 13.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Göteborgsvägen 31, House V3/SU, 43180, Mölndal, Sweden.

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February 2019

Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology.

Alzheimers Dement 2019 01 12;15(1):55-64. Epub 2018 Oct 12.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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January 2019

The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease.

Acta Neuropathol 2019 01 22;137(1):89-102. Epub 2018 Sep 22.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital/Mölndal, S-431 80, Mölndal, Sweden.

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January 2019

Fluid-based proteomics targeted on pathophysiological processes and pathologies in neurodegenerative diseases.

J Neurochem 2019 11 12;151(4):417-434. Epub 2018 Nov 12.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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November 2019

Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase.

Mol Neurodegener 2018 08 29;13(1):47. Epub 2018 Aug 29.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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August 2018

Biology/Disease-Driven Initiative on Protein-Aggregation Diseases of the Human Proteome Project: Goals and Progress to Date.

J Proteome Res 2018 12 28;17(12):4072-4084. Epub 2018 Sep 28.

Institute of Molecular Systems Biology, Department of Biology , ETH Zurich , Otto-Stern-Weg 3 , 8093 Zurich , Switzerland.

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December 2018

The presubiculum is preserved from neurodegenerative changes in Alzheimer's disease.

Acta Neuropathol Commun 2018 07 20;6(1):62. Epub 2018 Jul 20.

The Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, WC1N 3BG, UK.

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July 2018

Update on biomarkers for amyloid pathology in Alzheimer's disease.

Biomark Med 2018 07 15;12(7):799-812. Epub 2018 Jun 15.

Department of Psychiatry & Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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July 2018