Publications by authors named "Erik Ladewig"

14Publications

FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer.

Authors:
Amaia Arruabarrena-Aristorena Jesper L V Maag Srushti Kittane Yanyan Cai Wouter R Karthaus Erik Ladewig Jane Park Srinivasaraghavan Kannan Lorenzo Ferrando Emiliano Cocco Sik Y Ho Daisylyn S Tan Mirna Sallaku Fan Wu Barbara Acevedo Pier Selenica Dara S Ross Matthew Witkin Charles L Sawyers Jorge S Reis-Filho Chandra S Verma Ralf Jauch Richard Koche José Baselga Pedram Razavi Eneda Toska Maurizio Scaltriti

Cancer Cell 2020 Oct 3;38(4):534-550.e9. Epub 2020 Sep 3.

Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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October 2020

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer.

Authors:
Guotai Xu Sagar Chhangawala Emiliano Cocco Pedram Razavi Yanyan Cai Jordan E Otto Lorenzo Ferrando Pier Selenica Erik Ladewig Carmen Chan Arnaud Da Cruz Paula Matthew Witkin Yuanming Cheng Jane Park Cristian Serna-Tamayo HuiYong Zhao Fan Wu Mirna Sallaku Xuan Qu Alison Zhao Clayton K Collings Andrew R D'Avino Komal Jhaveri Richard Koche Ross L Levine Jorge S Reis-Filho Cigall Kadoch Maurizio Scaltriti Christina S Leslie José Baselga Eneda Toska

Nat Genet 2020 02 13;52(2):198-207. Epub 2020 Jan 13.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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February 2020

Double mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.

Authors:
Neil Vasan Pedram Razavi Jared L Johnson Hong Shao Hardik Shah Alesia Antoine Erik Ladewig Alexander Gorelick Ting-Yu Lin Eneda Toska Guotai Xu Abiha Kazmi Matthew T Chang Barry S Taylor Maura N Dickler Komal Jhaveri Sarat Chandarlapaty Raul Rabadan Ed Reznik Melissa L Smith Robert Sebra Frauke Schimmoller Timothy R Wilson Lori S Friedman Lewis C Cantley Maurizio Scaltriti José Baselga

Science 2019 11;366(6466):714-723

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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November 2019

Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma.

Authors:
Hee Jin Cho Junfei Zhao Sang Won Jung Erik Ladewig Doo-Sik Kong Yeon-Lim Suh Yeri Lee Donggeon Kim Sun Hee Ahn Mykola Bordyuh Hyun Ju Kang Jason K Sa Yun Jee Seo Sung Tae Kim Do Hoon Lim Yun-Sik Dho Jung-Il Lee Ho Jun Seol Jung Won Choi Woong-Yang Park Chul-Kee Park Raul Rabadan Do-Hyun Nam

Neuro Oncol 2019 01;21(1):47-58

Institute for Refractory Cancer Research, Seoul, Korea.

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January 2019

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma.

Authors:
Enrico Tiacci Erik Ladewig Gianluca Schiavoni Alex Penson Elisabetta Fortini Valentina Pettirossi Yuchun Wang Ariele Rosseto Alessandra Venanzi Sofija Vlasevska Roberta Pacini Simonetta Piattoni Alessia Tabarrini Alessandra Pucciarini Barbara Bigerna Alessia Santi Alessandro M Gianni Simonetta Viviani Antonello Cabras Stefano Ascani Barbara Crescenzi Cristina Mecucci Laura Pasqualucci Raul Rabadan Brunangelo Falini

Blood 2018 05 12;131(22):2454-2465. Epub 2018 Apr 12.

Institute of Hematology and Center for Hemato-Oncology Research, University and Hospital of Perugia, Perugia, Italy.

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May 2018

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.

Authors:
Junghyun Lim Pankaj Kumar Giri David Kazadi Brice Laffleur Wanwei Zhang Veronika Grinstein Evangelos Pefanis Lewis M Brown Erik Ladewig Ophélie Martin Yuling Chen Raul Rabadan François Boyer Gerson Rothschild Michel Cogné Eric Pinaud Haiteng Deng Uttiya Basu

Cell 2017 04;169(3):523-537.e15

Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address:

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April 2017

Spatiotemporal genomic architecture informs precision oncology in glioblastoma.

Authors:
Jin-Ku Lee Jiguang Wang Jason K Sa Erik Ladewig Hae-Ock Lee In-Hee Lee Hyun Ju Kang Daniel S Rosenbloom Pablo G Camara Zhaoqi Liu Patrick van Nieuwenhuizen Sang Won Jung Seung Won Choi Junhyung Kim Andrew Chen Kyu-Tae Kim Sang Shin Yun Jee Seo Jin-Mi Oh Yong Jae Shin Chul-Kee Park Doo-Sik Kong Ho Jun Seol Andrew Blumberg Jung-Il Lee Antonio Iavarone Woong-Yang Park Raul Rabadan Do-Hyun Nam

Nat Genet 2017 Apr 6;49(4):594-599. Epub 2017 Mar 6.

Institute for Refractory Cancer Research, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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April 2017

Clonal evolution of glioblastoma under therapy.

Authors:
Jiguang Wang Emanuela Cazzato Erik Ladewig Veronique Frattini Daniel I S Rosenbloom Sakellarios Zairis Francesco Abate Zhaoqi Liu Oliver Elliott Yong-Jae Shin Jin-Ku Lee In-Hee Lee Woong-Yang Park Marica Eoli Andrew J Blumberg Anna Lasorella Do-Hyun Nam Gaetano Finocchiaro Antonio Iavarone Raul Rabadan

Nat Genet 2016 07 6;48(7):768-76. Epub 2016 Jun 6.

Department of Systems Biology, Columbia University, New York, New York, USA.

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July 2016

Analysis of Nearly One Thousand Mammalian Mirtrons Reveals Novel Features of Dicer Substrates.

Authors:
Jiayu Wen Erik Ladewig Sol Shenker Jaaved Mohammed Eric C Lai

PLoS Comput Biol 2015 Sep 1;11(9):e1004441. Epub 2015 Sep 1.

Department of Developmental Biology, Sloan-Kettering Institute, New York, New York, United States of America.

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September 2015

Comparative analysis of the transcriptome across distant species.

Authors:
Mark B Gerstein Joel Rozowsky Koon-Kiu Yan Daifeng Wang Chao Cheng James B Brown Carrie A Davis LaDeana Hillier Cristina Sisu Jingyi Jessica Li Baikang Pei Arif O Harmanci Michael O Duff Sarah Djebali Roger P Alexander Burak H Alver Raymond Auerbach Kimberly Bell Peter J Bickel Max E Boeck Nathan P Boley Benjamin W Booth Lucy Cherbas Peter Cherbas Chao Di Alex Dobin Jorg Drenkow Brent Ewing Gang Fang Megan Fastuca Elise A Feingold Adam Frankish Guanjun Gao Peter J Good Roderic Guigó Ann Hammonds Jen Harrow Roger A Hoskins Cédric Howald Long Hu Haiyan Huang Tim J P Hubbard Chau Huynh Sonali Jha Dionna Kasper Masaomi Kato Thomas C Kaufman Robert R Kitchen Erik Ladewig Julien Lagarde Eric Lai Jing Leng Zhi Lu Michael MacCoss Gemma May Rebecca McWhirter Gennifer Merrihew David M Miller Ali Mortazavi Rabi Murad Brian Oliver Sara Olson Peter J Park Michael J Pazin Norbert Perrimon Dmitri Pervouchine Valerie Reinke Alexandre Reymond Garrett Robinson Anastasia Samsonova Gary I Saunders Felix Schlesinger Anurag Sethi Frank J Slack William C Spencer Marcus H Stoiber Pnina Strasbourger Andrea Tanzer Owen A Thompson Kenneth H Wan Guilin Wang Huaien Wang Kathie L Watkins Jiayu Wen Kejia Wen Chenghai Xue Li Yang Kevin Yip Chris Zaleski Yan Zhang Henry Zheng Steven E Brenner Brenton R Graveley Susan E Celniker Thomas R Gingeras Robert Waterston

Nature 2014 Aug;512(7515):445-8

1] Department of Genome Sciences and University of Washington School of Medicine, William H. Foege Building S350D, 1705 Northeast Pacific Street, Box 355065 Seattle, Washington 98195-5065, USA [2].

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August 2014

Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines.

Authors:
Jiayu Wen Jaaved Mohammed Diane Bortolamiol-Becet Harrison Tsai Nicolas Robine Jakub O Westholm Erik Ladewig Qi Dai Katsutomo Okamura Alex S Flynt Dayu Zhang Justen Andrews Lucy Cherbas Thomas C Kaufman Peter Cherbas Adam Siepel Eric C Lai

Genome Res 2014 Jul;24(7):1236-50

Department of Developmental Biology, Sloan-Kettering Institute, New York, New York 10065, USA;

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July 2014

Functional small RNAs are generated from select miRNA hairpin loops in flies and mammals.

Authors:
Katsutomo Okamura Erik Ladewig Li Zhou Eric C Lai

Genes Dev 2013 Apr 27;27(7):778-92. Epub 2013 Mar 27.

Department of Developmental Biology, Sloan-Kettering Institute, New York, New York 10065, USA.

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April 2013

Discovery of hundreds of mirtrons in mouse and human small RNA data.

Authors:
Erik Ladewig Katsutomo Okamura Alex S Flynt Jakub O Westholm Eric C Lai

Genome Res 2012 Sep;22(9):1634-45

Department of Developmental Biology, Sloan-Kettering Institute, New York, New York 10065, USA.

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September 2012

Common and distinct patterns of terminal modifications to mirtrons and canonical microRNAs.

Authors:
Jakub O Westholm Erik Ladewig Katsutomo Okamura Nicolas Robine Eric C Lai

RNA 2012 Feb 21;18(2):177-92. Epub 2011 Dec 21.

Department of Developmental Biology, Sloan-Kettering Institute, New York, NY 10065, USA.

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February 2012