Publications by authors named "Erica N Borducchi"

41Publications

Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation.

Authors:
Po-Ting Liu Brandon F Keele Peter Abbink Noe B Mercado Jinyan Liu Esther A Bondzie Abishek Chandrashekar Erica N Borducchi Joseph Hesselgesser Michael Mish Gregory Chin Elena Bekerman Romas Geleziunas Dan H Barouch

Nat Commun 2020 10 27;11(1):5412. Epub 2020 Oct 27.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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October 2020

Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques.

Authors:
Galit Alter Wen-Han Yu Abishek Chandrashekar Erica N Borducchi Khader Ghneim Ashish Sharma Rebecca Nedellec Katherine R McKenney Caitlyn Linde Thomas Broge Todd J Suscovich Tom Linnekin Peter Abbink Noe B Mercado Joseph P Nkolola Katherine McMahan Esther A Bondzie Venous Hamza Lauren Peter Nicole Kordana Shant Mahrokhian Michael S Seaman Wenjun Li Mark G Lewis Douglas A Lauffenburger Lars Hangartner Rafick-Pierre Sekaly Dan H Barouch

Cell 2020 Oct;183(1):185-196.e14

Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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October 2020

Safety and immunogenicity of a Zika purified inactivated virus vaccine given via standard, accelerated, or shortened schedules: a single-centre, double-blind, sequential-group, randomised, placebo-controlled, phase 1 trial.

Authors:
Kathryn E Stephenson Chen Sabrina Tan Stephen R Walsh Andrew Hale Jessica L Ansel Diane G Kanjilal Kate Jaegle Lauren Peter Erica N Borducchi Joseph P Nkolola Tatenda Makoni Rachel Fogel Connor Bradshaw Anna Tyler Edward Moseley Abishek Chandrashekar Katherine E Yanosick Michael S Seaman Kenneth H Eckels Rafael A De La Barrera Jason Thompson Peter Dawson Stephen J Thomas Nelson L Michael Kayvon Modjarrad Dan H Barouch

Lancet Infect Dis 2020 09 6;20(9):1061-1070. Epub 2020 May 6.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA. Electronic address:

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September 2020

Sustained maternal antibody and cellular immune responses in pregnant women infected with Zika virus and mother to infant transfer of Zika-specific antibodies.

Authors:
Ai-Ris Y Collier Erica N Borducchi Abishek Chandrashekar Edward Moseley Lauren Peter Nicholas S Teodoro Joseph Nkolola Peter Abbink Dan H Barouch

Am J Reprod Immunol 2020 10 1;84(4):e13288. Epub 2020 Jul 1.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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October 2020

Differential Outcomes following Optimization of Simian-Human Immunodeficiency Viruses from Clades AE, B, and C.

Authors:
Lawrence J Tartaglia Siddhant Gupte Kevin C Pastores Sebastien Trott Peter Abbink Noe B Mercado Zhenfeng Li Po-Ting Liu Erica N Borducchi Abishek Chandrashekar Esther Apraku Bondzie Venous Hamza Nicole Kordana Shant Mahrokhian Christy L Lavine Michael S Seaman Hui Li George M Shaw Dan H Barouch

J Virol 2020 05 4;94(10). Epub 2020 May 4.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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May 2020

Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17-22).

Authors:
Kathryn E Stephenson Frank Wegmann Frank Tomaka Stephen R Walsh C Sabrina Tan Ludo Lavreys Jessica L Ansel Diane G Kanjilal Kate Jaegle Joseph P Nkolola Lauren Peter Rachel Fogel Connor Bradshaw Anna Tyler Tatenda Makoni Lisa Howe Darla Quijada Abishek Chandrashekar Esther A Bondzie Erica N Borducchi Katherine E Yanosick Jenny Hendriks Steven Nijs Carla Truyers Jeroen Tolboom Roland C Zahn Michael S Seaman Galit Alter Daniel J Stieh Maria Grazia Pau Hanneke Schuitemaker Dan H Barouch

Lancet HIV 2020 06 17;7(6):e410-e421. Epub 2020 Feb 17.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA. Electronic address:

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June 2020

Adenovirus Vector-Based Vaccines Confer Maternal-Fetal Protection against Zika Virus Challenge in Pregnant IFN-αβR Mice.

Authors:
Rafael A Larocca Erica A Mendes Peter Abbink Rebecca L Peterson Amanda J Martinot Mark Justin Iampietro Zi H Kang Malika Aid Marinela Kirilova Catherine Jacob-Dolan Lisa Tostanoski Erica N Borducchi Rafael A De La Barrera Dan H Barouch

Cell Host Microbe 2019 11 24;26(5):591-600.e4. Epub 2019 Oct 24.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA. Electronic address:

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November 2019

Lack of therapeutic efficacy of an antibody to αβ in SIVmac251-infected rhesus macaques.

Authors:
Peter Abbink Noe B Mercado Joseph P Nkolola Rebecca L Peterson Hubert Tuyishime Katherine McMahan Edward T Moseley Erica N Borducchi Abishek Chandrashekar Esther A Bondzie Arshi Agarwal Aaron J Belli Keith A Reimann Brandon F Keele Romas Geleziunas Mark G Lewis Dan H Barouch

Science 2019 09 5;365(6457):1029-1033. Epub 2019 Sep 5.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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September 2019

Publisher Correction: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys.

Authors:
Erica N Borducchi Jinyan Liu Joseph P Nkolola Anthony M Cadena Wen-Han Yu Stephanie Fischinger Thomas Broge Peter Abbink Noe B Mercado Abishek Chandrashekar David Jetton Lauren Peter Katherine McMahan Edward T Moseley Elena Bekerman Joseph Hesselgesser Wenjun Li Mark G Lewis Galit Alter Romas Geleziunas Dan H Barouch

Nature 2018 12;564(7734):E8

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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December 2018

Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys.

Authors:
Erica N Borducchi Jinyan Liu Joseph P Nkolola Anthony M Cadena Wen-Han Yu Stephanie Fischinger Thomas Broge Peter Abbink Noe B Mercado Abishek Chandrashekar David Jetton Lauren Peter Katherine McMahan Edward T Moseley Elena Bekerman Joseph Hesselgesser Wenjun Li Mark G Lewis Galit Alter Romas Geleziunas Dan H Barouch

Nature 2018 11 3;563(7731):360-364. Epub 2018 Oct 3.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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November 2018

Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19).

Authors:
Dan H Barouch Frank L Tomaka Frank Wegmann Daniel J Stieh Galit Alter Merlin L Robb Nelson L Michael Lauren Peter Joseph P Nkolola Erica N Borducchi Abishek Chandrashekar David Jetton Kathryn E Stephenson Wenjun Li Bette Korber Georgia D Tomaras David C Montefiori Glenda Gray Nicole Frahm M Juliana McElrath Lindsey Baden Jennifer Johnson Julia Hutter Edith Swann Etienne Karita Hannah Kibuuka Juliet Mpendo Nigel Garrett Kathy Mngadi Kundai Chinyenze Frances Priddy Erica Lazarus Fatima Laher Sorachai Nitayapan Punnee Pitisuttithum Stephan Bart Thomas Campbell Robert Feldman Gregg Lucksinger Caroline Borremans Katleen Callewaert Raphaele Roten Jerald Sadoff Lorenz Scheppler Mo Weijtens Karin Feddes-de Boer Daniëlle van Manen Jessica Vreugdenhil Roland Zahn Ludo Lavreys Steven Nijs Jeroen Tolboom Jenny Hendriks Zelda Euler Maria G Pau Hanneke Schuitemaker

Lancet 2018 07 6;392(10143):232-243. Epub 2018 Jul 6.

Janssen Vaccines & Prevention BV, Leiden, Netherlands.

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July 2018

Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys.

Authors:
Peter Abbink Rafael A Larocca Wanwisa Dejnirattisai Rebecca Peterson Joseph P Nkolola Erica N Borducchi Piyada Supasa Juthathip Mongkolsapaya Gavin R Screaton Dan H Barouch

Nat Med 2018 06 4;24(6):721-723. Epub 2018 Jun 4.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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June 2018

Similar Epitope Specificities of IgG and IgA Antibodies Elicited by Ad26 Vector Prime, Env Protein Boost Immunizations in Rhesus Monkeys.

Authors:
Zi Han Kang Christine A Bricault Erica N Borducchi Kathryn E Stephenson Michael S Seaman Maria Pau Hanneke Schuitemaker Danielle van Manen Frank Wegmann Dan H Barouch

J Virol 2018 08 17;92(15). Epub 2018 Jul 17.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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August 2018

First-in-Human Randomized, Controlled Trial of Mosaic HIV-1 Immunogens Delivered via a Modified Vaccinia Ankara Vector.

Authors:
Lindsey R Baden Stephen R Walsh Michael S Seaman Yehuda Z Cohen Jennifer A Johnson J Humberto Licona Rachel D Filter Jane A Kleinjan Jon A Gothing Julia Jennings Lauren Peter Joseph Nkolola Peter Abbink Erica N Borducchi Marinela Kirilova Kathryn E Stephenson Poonam Pegu Michael A Eller Hung V Trinh Mangala Rao Julie A Ake Michal Sarnecki Steven Nijs Katleen Callewaert Hanneke Schuitemaker Jenny Hendriks Maria G Pau Frank Tomaka Bette T Korber Galit Alter Raphael Dolin Patricia L Earl Bernard Moss Nelson L Michael Merlin L Robb Dan H Barouch

J Infect Dis 2018 07;218(4):633-644

Harvard Medical School, Beth Israel Deaconess Medical Center, Boston.

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July 2018

Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys.

Authors:
Amanda J Martinot Peter Abbink Onur Afacan Anna K Prohl Roderick Bronson Jonathan L Hecht Erica N Borducchi Rafael A Larocca Rebecca L Peterson William Rinaldi Melissa Ferguson Peter J Didier Deborah Weiss Mark G Lewis Rafael A De La Barrera Edward Yang Simon K Warfield Dan H Barouch

Cell 2018 05 29;173(5):1111-1122.e10. Epub 2018 Mar 29.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA. Electronic address:

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May 2018

Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors.

Authors:
Peter Abbink Marinela Kirilova Michael Boyd Noe Mercado Zhenfeng Li Ramya Nityanandam Ovini Nanayakkara Rebecca Peterson Rafael A Larocca Malika Aid Lawrence Tartaglia Tinaye Mutetwa Eryn Blass David Jetton Lori F Maxfield Erica N Borducchi Alexander Badamchi-Zadeh Scott Handley Guoyan Zhao Herbert W Virgin Menzo J Havenga Dan H Barouch

J Virol 2018 03 26;92(6). Epub 2018 Feb 26.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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March 2018

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys.

Authors:
Peter Abbink Rafael A Larocca Kittipos Visitsunthorn Michael Boyd Rafael A De La Barrera Gregory D Gromowski Marinela Kirilova Rebecca Peterson Zhenfeng Li Ovini Nanayakkara Ramya Nityanandam Noe B Mercado Erica N Borducchi Abishek Chandrashekar David Jetton Shanell Mojta Priya Gandhi Jake LeSuer Shreeya Khatiwada Mark G Lewis Kayvon Modjarrad Richard G Jarman Kenneth H Eckels Stephen J Thomas Nelson L Michael Dan H Barouch

Sci Transl Med 2017 Dec;9(420)

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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December 2017

Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail.

Authors:
Boris Julg Po-Ting Liu Kshitij Wagh William M Fischer Peter Abbink Noe B Mercado James B Whitney Joseph P Nkolola Katherine McMahan Lawrence J Tartaglia Erica N Borducchi Shreeya Khatiwada Megha Kamath Jake A LeSuer Michael S Seaman Stephen D Schmidt John R Mascola Dennis R Burton Bette T Korber Dan H Barouch

Sci Transl Med 2017 Sep;9(408)

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

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September 2017

Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys.

Authors:
Brandon F Keele Wenjun Li Erica N Borducchi Joseph P Nkolola Peter Abbink Bing Chen Michael S Seaman Dan H Barouch

Nat Commun 2017 06 5;8:15740. Epub 2017 Jun 5.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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June 2017

Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys.

Authors:
Malika Aid Peter Abbink Rafael A Larocca Michael Boyd Ramya Nityanandam Ovini Nanayakkara Amanda J Martinot Edward T Moseley Eryn Blass Erica N Borducchi Abishek Chandrashekar Amanda L Brinkman Katherine Molloy David Jetton Lawrence J Tartaglia Jinyan Liu Katharine Best Alan S Perelson Rafael A De La Barrera Mark G Lewis Dan H Barouch

Cell 2017 05 27;169(4):610-620.e14. Epub 2017 Apr 27.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA. Electronic address:

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May 2017