Publications by authors named "Eric-Wubbo Lameijer"

13Publications

Precision Medicine: What Challenges Are We Facing?

Genomics Proteomics Bioinformatics 2016 10 13;14(5):253-261. Epub 2016 Oct 13.

CAS Key Laboratory of Genome Sciences and Information, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2016.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093857PMC
October 2016

An integrated map of structural variation in 2,504 human genomes.

Nature 2015 Oct;526(7571):75-81

European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Meyerhofstr. 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature15394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617611PMC
October 2015

A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis.

Ann Rheum Dis 2015 Sep 17;74(9):1756-62. Epub 2014 Apr 17.

Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2013-20514
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http://dx.doi.org/10.1136/annrheumdis-2013-205149DOI Listing
September 2015

PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data.

Bioinformatics 2012 Feb 4;28(4):479-86. Epub 2012 Jan 4.

Department of Molecular Epidemiology, Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/btr712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278765PMC
February 2012

Designing active template molecules by combining computational de novo design and human chemist's expertise.

J Med Chem 2007 Apr 17;50(8):1925-32. Epub 2007 Mar 17.

Leiden/Amsterdam Center for Drug Research, Division of Medicinal Chemistry, Leiden University, Post Office Box 9502, 2300RA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/jm061356+DOI Listing
April 2007

Mining a chemical database for fragment co-occurrence: discovery of "chemical clichés".

J Chem Inf Model 2006 Mar-Apr;46(2):553-62

Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/ci050370cDOI Listing
September 2006

The molecule evoluator. An interactive evolutionary algorithm for the design of drug-like molecules.

J Chem Inf Model 2006 Mar-Apr;46(2):545-52

Leiden/Amsterdam Center for Drug Research, Division of Medicinal Chemistry, P.O. Box 9502, 2300RA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/ci050369dDOI Listing
September 2006

A two-entropies analysis to identify functional positions in the transmembrane region of class A G protein-coupled receptors.

Proteins 2006 Jun;63(4):1018-30

Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/prot.20899DOI Listing
June 2006