Publications by authors named "Eric Vivier"

100Publications

Tumor-Infiltrating Natural Killer Cells.

Cancer Discov 2020 Dec 4. Epub 2020 Dec 4.

Innate Pharma Research Laboratories, Innate Pharma, Marseille, France.

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December 2020

Multidimensional molecular controls defining NK/ILC1 identity in cancers.

Semin Immunol 2020 Nov 30:101424. Epub 2020 Nov 30.

Aix Marseille University, CNRS, INSERM, CIML, Marseille, France. Electronic address:

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November 2020

Natural killers or ILC1s? That is the question.

Curr Opin Immunol 2020 Oct 13;68:48-53. Epub 2020 Oct 13.

Aix Marseille Univ, CNRS, INSERM, CIML, Marseille, France; Assistance Publique des Hôpitaux de Marseille, Hôpital de la Timone, Immunology, Marseille Immunopole, France; Innate Pharma, Marseille, France.

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October 2020

Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells.

Cell Rep 2020 07;32(1):107855

Division of Biology and Medicine, Department of Molecular Microbiology and Immunology, Brown University Alpert Medical School, Providence, RI 02912, USA. Electronic address:

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July 2020

Maternal diesel particle exposure promotes offspring asthma through NK cell-derived granzyme B.

J Clin Invest 2020 Aug;130(8):4133-4151

Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health (NJH), Denver, Colorado, USA.

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August 2020

Immuno-Oncology beyond TILs: Unleashing TILCs.

Cancer Cell 2020 04;37(4):428-430

Innate Pharma Research Laboratories, Innate Pharma, Marseille, France; Aix Marseille University, CNRS, INSERM, CIML, Marseille, France; APHM, Hôpital de la Timone, Service d'Immunologie, Marseille-Immunopôle, Marseille, France.

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April 2020

SnapShot: Natural Killer Cells.

Cell 2020 03;180(6):1280-1280.e1

Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France; Immunology, Marseille Immunopole, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille, France; Innate Pharma Research Laboratories, Innate Pharma, Marseille, France.

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March 2020

A comprehensive approach to gene expression profiling in immune cells.

Methods Enzymol 2020 7;636:1-47. Epub 2019 Aug 7.

Innate Pharma Research Laboratories, Innate Pharma, Marseille, France; Aix-Marseille Univ, APHM, CNRS, INSERM, CIML, Hôpital de la Timone, Marseille-Immunopole, Marseille, France. Electronic address:

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August 2019

Boosting Cytotoxic Antibodies against Cancer.

Cell 2020 03;180(5):822-824

Innate Pharma Research Laboratories, Innate Pharma, Marseille, France; Aix Marseille Université, CNRS, INSERM, CIML, Marseille, France; APHM, Hôpital de la Timone, Service d'Immunologie, Marseille-Immunopôle, Marseille, France.

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March 2020

[Natural killer cells: promising targets in cancer therapy].

Med Sci (Paris) 2019 Dec 6;35(12):990-992. Epub 2020 Jan 6.

Innate Pharma, Marseille, France - Aix Marseille Université, Inserm, CNRS, Centre d'Immunologie de Marseille-Luminy, Marseille, France - Service d'Immunologie, Marseille Immunopole, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France.

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December 2019

Monalizumab: inhibiting the novel immune checkpoint NKG2A.

J Immunother Cancer 2019 10 17;7(1):263. Epub 2019 Oct 17.

Innate Pharma Research Labs, Innate Pharma, Marseille, France.

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October 2019

Harnessing innate immunity in cancer therapy.

Nature 2019 10 2;574(7776):45-56. Epub 2019 Oct 2.

Innate Pharma, Marseille, France.

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October 2019

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity.

Sci Signal 2019 08 27;12(596). Epub 2019 Aug 27.

Division of Molecular Immunology, The Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria 3052, Australia.

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August 2019

Identification of the E3 Ligase TRIM29 as a Critical Checkpoint Regulator of NK Cell Functions.

J Immunol 2019 08 3;203(4):873-880. Epub 2019 Jul 3.

Immunobiology and Transplant Science Center, Houston Methodist Hospital, Houston, TX 77030;

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August 2019

Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity.

Cell 2019 06 30;177(7):1701-1713.e16. Epub 2019 May 30.

Innate Pharma, Marseille, France; Aix Marseille Université, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, Marseille, France; Service d'Immunologie, Marseille Immunopole, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France. Electronic address:

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June 2019

The Innate Part of the Adaptive Immune System.

Clin Rev Allergy Immunol 2020 Apr;58(2):151-154

UMR1227, Lymphocytes B et Autoimmunité, Univ Brest, Brest, France.

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April 2020

Helper-like innate lymphoid cells and cancer immunotherapy.

Semin Immunol 2019 02 6;41:101274. Epub 2019 May 6.

Innate Pharma Research Laboratories, Innate Pharma, Marseille, France. Electronic address:

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February 2019

Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2.

EMBO J 2019 06 18;38(11). Epub 2019 Apr 18.

Université Côte d'Azur, Centre National de la Recherche Scientifique (CNRS) UMR7284, Institut National de la Santé et de la Recherche Médicale (INSERM) U1081, Institute for Research on Cancer and Aging, Nice (IRCAN), Nice, France

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June 2019

Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2.

Nature 2019 04 3;568(7752):405-409. Epub 2019 Apr 3.

Division of Gastroenterology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.

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April 2019

Targeting natural killer cells in solid tumors.

Cell Mol Immunol 2019 05 25;16(5):415-422. Epub 2019 Mar 25.

Aix Marseille Université, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

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May 2019

Chemotherapy and tumor immunity.

Science 2018 12;362(6421):1355-1356

Innate Pharma, Marseille, France.

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December 2018

Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells.

Cell 2018 12 29;175(7):1731-1743.e13. Epub 2018 Nov 29.

Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France; Aix Marseille Université, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, 13009 Marseille, France; Service d'Immunologie, Marseille Immunopole, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, 13005 Marseille, France. Electronic address:

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December 2018

High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice.

Immunity 2018 11 6;49(5):971-986.e5. Epub 2018 Nov 6.

Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France; Immunology, Marseille Immunopole, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille, France; Innate Pharma Research Laboratories, Innate Pharma, Marseille, France. Electronic address:

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November 2018

Author Correction: Natural killer cells and other innate lymphoid cells in cancer.

Nat Rev Immunol 2018 Nov;18(11):726

Innate Pharma Research Labs, Innate Pharma, Marseille, France.

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November 2018

Neuroendocrine regulation of innate lymphoid cells.

Immunol Rev 2018 11;286(1):120-136

Aix Marseille Univ, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

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November 2018

Natural killer cells and other innate lymphoid cells in cancer.

Nat Rev Immunol 2018 11;18(11):671-688

Innate Pharma Research Labs, Innate Pharma, Marseille, France.

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November 2018

Innate Lymphoid Cells: 10 Years On.

Cell 2018 08;174(5):1054-1066

Department of Experimental Immunology Academic Medical Center of the University of Amsterdam, Amsterdam, the Netherlands.

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August 2018

Reply to 'Comment on: Evidence of innate lymphoid cell redundancy in humans'.

Nat Immunol 2018 08;19(8):789-790

APHP, Hôpital Universitaire Necker-Enfants Malades, Centre de Référence Déficits Immunitaires Héréditaires, Paris, France.

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August 2018

Activating and inhibitory receptors expressed on innate lymphoid cells.

Semin Immunopathol 2018 07 22;40(4):331-341. Epub 2018 May 22.

Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

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July 2018

ILC2 memory: Recollection of previous activation.

Immunol Rev 2018 05;283(1):41-53

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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May 2018

Crk Adaptor Proteins Regulate NK Cell Expansion and Differentiation during Mouse Cytomegalovirus Infection.

J Immunol 2018 05 4;200(10):3420-3428. Epub 2018 Apr 4.

Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030;

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May 2018

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo.

Cell Rep 2018 04;23(1):39-49

Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland. Electronic address:

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April 2018

NKG2D-MICA Interaction: A Paradigm Shift in Innate Recognition.

J Immunol 2018 04;200(7):2229-2230

Innate Pharma, 13276 Marseille, France.

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April 2018

The immunological functions of the Appendix: An example of redundancy?

Semin Immunol 2018 04 2;36:31-44. Epub 2018 Mar 2.

Innate Pharma Research Labs, Innate Pharma, Marseille; Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France; Service d'Immunologie, Marseille Immunopole, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille. Electronic address:

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April 2018

[New frontiers in the fight against cancer].

Biol Aujourdhui 2018 11;212(3-4):61-67. Epub 2019 Apr 11.

Innate Pharma Research Labs, Innate Pharma, 117 avenue de Luminy, 13009 Marseille, France - Aix Marseille Université, CNRS, INSERM, CIML, Marseille, France - Service d'Immunologie, Marseille Immunopôle, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, 278 rue Saint-Pierre, 13005 Marseille, France.

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August 2019

ITIMs: episode 1 of the inhibitory saga.

Authors:
Eric Vivier

Nat Rev Immunol 2018 01 27;18(1). Epub 2017 Nov 27.

Universit d'Aix-Marseille, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

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January 2018

Host resistance to endotoxic shock requires the neuroendocrine regulation of group 1 innate lymphoid cells.

J Exp Med 2017 Dec 15;214(12):3531-3541. Epub 2017 Nov 15.

Aix-Marseille Université, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France

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December 2017

Editorial: NK Cell Subsets in Health and Disease: New Developments.

Front Immunol 2017 18;8:1363. Epub 2017 Oct 18.

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France.

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October 2017

Genetic Depletion or Hyperresponsiveness of Natural Killer Cells Do Not Affect Atherosclerosis Development.

Circ Res 2018 01 18;122(1):47-57. Epub 2017 Oct 18.

From the Institut National de la Santé et de la Recherche Médicale (Inserm), Unit 970, Paris-Cardiovascular Research Center, Université Paris-Descartes, France (W.N.-E., J.J., B.E., A.G., L.Z., J.V., P.B., H.A.-O., Z.M., A.T.); ER045, PRASE (W.N.-E., K.Z.) and Biology Department, Faculty of Sciences-I (K.Z.), Lebanese University, Beirut, Lebanon; Department of Anatomopathology, Hôpital Européen Georges Pompidou, Assistance Publique-Hopitaux de Paris, France (M.T., P.B.); Centre d'Immunologie de Marseille-Luminy, Aix Marseille University, CNRS, INSERM, France (E.V., S.U.); and Division of Cardiovascular Medicine, Department of Medicine, University of Cambridge, United Kingdom (Z.M.).

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January 2018

Natural killer cell immunotherapies against cancer: checkpoint inhibitors and more.

Semin Immunol 2017 06 22;31:55-63. Epub 2017 Sep 22.

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, Inserm, CNRS, Marseille, France; Service d'Immunologie, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France.

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June 2017

Natural-Killer-like B Cells Display the Phenotypic and Functional Characteristics of Conventional B Cells.

Immunity 2017 08;47(2):199-200

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France; Service d'Immunologie, Hôpital de la Timone, Assistance Publique - Hôpitaux de Marseille, Marseille, France.

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August 2017

T-bet-dependent NKp46 innate lymphoid cells regulate the onset of T17-induced neuroinflammation.

Nat Immunol 2017 Oct 14;18(10):1117-1127. Epub 2017 Aug 14.

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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October 2017

Innate lymphoid cells: major players in inflammatory diseases.

Nat Rev Immunol 2017 Nov 14;17(11):665-678. Epub 2017 Aug 14.

Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

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November 2017

[Innate lymphoid cells].

Med Sci (Paris) 2017 May 14;33(5):534-542. Epub 2017 Jun 14.

Aix Marseille Université, CNRS, Inserm, CIML, Marseille, France - APHM, Hôpital de la Timone, Service d'immunologie, Marseille, France.

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May 2017

Immune checkpoints on innate lymphoid cells.

J Exp Med 2017 06 17;214(6):1561-1563. Epub 2017 May 17.

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France; Service d'Immunologie, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France.

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June 2017

The discontinuity theory of immunity.

Sci Immunol 2016 Jul;1(1)

Centre d'Immunologie de Marseille-Luminy, Université Aix-Marseille UM2, INSERM, U1104, CNRS UMR 7258, 13288 Marseille, France; Immunologie, Hôpital de la Conception, Assistance Publique - Hôpitaux de Marseille, Aix-Marseille Université, 13005 Marseille, France.

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July 2016

Killer ILCs in the Fat.

Immunity 2017 02;46(2):169-171

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, 13009 Marseille, France; Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, 13009 Marseille, France.

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February 2017

Trans-inhibition of activation and proliferation signals by Fc receptors in mast cells and basophils.

Sci Signal 2016 12 20;9(459):ra126. Epub 2016 Dec 20.

Institut Pasteur, Département d'Immunologie, Unité d'Allergologie Moléculaire et Cellulaire, Paris, France.

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December 2016

Manufacturing Natural Killer Cells as Medicinal Products.

Front Immunol 2016 15;7:504. Epub 2016 Nov 15.

CBT-1409: INSERM, Aix Marseille Univ, Institut Paoli-Calmettes, AP-HM, Marseille, France; CRCM: INSERM, CNRS, Aix Marseille Univ, Institut Paoli-Calmettes, CRCM, Marseille, France.

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November 2016

Structural Insights into the Inhibitory Mechanism of an Antibody against B7-H6, a Stress-Induced Cellular Ligand for the Natural Killer Cell Receptor NKp30.

J Mol Biol 2016 11 20;428(22):4457-4466. Epub 2016 Sep 20.

University of Maryland Institute for Bioscience and Biotechnology Research, W.M. Keck Laboratory for Structural Biology, Rockville, MD 20850, USA; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA. Electronic address:

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November 2016

PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma.

Oncotarget 2016 11;7(45):72961-72977

Institut National de Recherche Médicale (INSERM) UMR1149, Centre de Recherche Sur l'Inflammation, Équipe Immunité Innée Chez l'Enfant, Hôpital Robert Debré, Paris, France.

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November 2016

HLA-Fatal attraction.

Nat Immunol 2016 08;17(9):1012-4

Centre d'Immunologie de Marseille-Luminy, Aix-Marseille Université, Inserm, CNRS, Marseille, France, and the Immunology department, Hôpital de la Conception, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France.

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August 2016

The evolution of innate lymphoid cells.

Nat Immunol 2016 06;17(7):790-4

The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.

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June 2016

Low Circulating Natural Killer Cell Counts are Associated With Severe Disease in Patients With Common Variable Immunodeficiency.

EBioMedicine 2016 Apr 2;6:222-230. Epub 2016 Mar 2.

Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University UM2, 13288 Marseille, France; Inserm U1104, 13288 Marseille, France; CNRS UMR7280, 13288 Marseille, France; MI-mAbs Consortium (Aix Marseille University), CIML, 13288 Marseille, France. Electronic address:

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April 2016

Transforming growth factor-β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells.

Sci Signal 2016 05 3;9(426):ra46. Epub 2016 May 3.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia. Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

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May 2016

Science Signaling Podcast for 3 May 2016: Innate lymphoid cell plasticity.

Sci Signal 2016 May 3;9(426):pc10. Epub 2016 May 3.

Web Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, NW, Washington, DC 20005, USA.

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May 2016

[Innate Lymphoid Cells: new actors of immunity].

Bull Acad Natl Med 2016 03;200(3):561-72; discussion 573-4

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March 2016

Murine peripheral NK-cell populations originate from site-specific immature NK cells more than from BM-derived NK cells.

Eur J Immunol 2016 05 31;46(5):1258-70. Epub 2016 Mar 31.

The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.

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May 2016

Cutting Edge: Eomesodermin Is Sufficient To Direct Type 1 Innate Lymphocyte Development into the Conventional NK Lineage.

J Immunol 2016 Feb 20;196(4):1449-54. Epub 2016 Jan 20.

Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032; Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032;

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February 2016

NK Cell-Specific Gata3 Ablation Identifies the Maturation Program Required for Bone Marrow Exit and Control of Proliferation.

J Immunol 2016 Feb 15;196(4):1753-67. Epub 2016 Jan 15.

Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada;

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February 2016

Editorial overview: Innate immunity.

Curr Opin Immunol 2016 Feb 28;38:v-vii. Epub 2015 Dec 28.

Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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February 2016

Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells.

Curr Opin Immunol 2016 Feb 29;38:86-93. Epub 2015 Dec 29.

The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia. Electronic address:

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February 2016

Innate Lymphoid Cells in Cancer.

Cancer Immunol Res 2015 Oct;3(10):1109-14

Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université UM2, Inserm, U1104, CNRS UMR7280, 13288 Marseille, France. Immunologie, Hôpital de la Conception, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France.

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October 2015