Publications by authors named "Eric Vangrevelinghe"

22Publications

Identification and characterization of a phenyl-thiazolyl-benzoic acid derivative as a novel RAR/RXR agonist.

Heliyon 2019 Nov 19;5(11):e02849. Epub 2019 Nov 19.

Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.

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November 2019

Discovery and Structural Characterization of ATP-Site Ligands for the Wild-Type and V617F Mutant JAK2 Pseudokinase Domain.

ACS Chem Biol 2019 04 11;14(4):587-593. Epub 2019 Mar 11.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Department of Cancer Biology , Dana-Farber Cancer Institute , Boston , Massachusetts 02115 , United States.

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April 2019

Indolyl-naphthyl-maleimides as potent and selective inhibitors of protein kinase C-α/β.

Bioorg Med Chem Lett 2017 02 16;27(4):781-786. Epub 2017 Jan 16.

Novartis Institutes for BioMedical Research, Forum 1, Novartis Campus, CH-4056 Basel, Switzerland.

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February 2017

Orally bioavailable Syk inhibitors with activity in a rat PK/PD model.

Bioorg Med Chem Lett 2015 Oct 18;25(20):4642-7. Epub 2015 Aug 18.

Autoimmunity, Transplantation and Inflammation Research, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.

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October 2015

Discovery and profiling of a selective and efficacious Syk inhibitor.

J Med Chem 2015 Feb 9;58(4):1950-63. Epub 2015 Feb 9.

Global Discovery Chemistry, ‡Analytical Sciences & Imaging, §Autoimmunity, Transplantation and Inflammation Research, Novartis Institutes for Biomedical Research , 4056 Basel, Switzerland.

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February 2015

Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension.

Bioorg Med Chem Lett 2014 Oct 6;24(20):4812-7. Epub 2014 Sep 6.

Novartis Institutes for Biomedical Research, Forum 1 Novartis Campus, 4056 Basel, Switzerland. Electronic address:

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October 2014

Identification of a potent Janus kinase 3 inhibitor with high selectivity within the Janus kinase family.

J Med Chem 2011 Jan 14;54(1):284-8. Epub 2010 Dec 14.

Novartis Institutes for BioMedical Research, Forum 1, Novartis Campus, Basel, Switzerland.

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January 2011

A small-molecule dengue virus entry inhibitor.

Antimicrob Agents Chemother 2009 May 17;53(5):1823-31. Epub 2009 Feb 17.

Novartis Institute for Tropical Diseases, 10 Biopolis Rd., Chromos Building, Singapore 138670, Singapore.

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May 2009