Publications by authors named "Eric Schulze-Bahr"

100Publications

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls.

Authors:
Roddy Walsh Najim Lahrouchi Rafik Tadros Florence Kyndt Charlotte Glinge Pieter G Postema Ahmad S Amin Eline A Nannenberg James S Ware Nicola Whiffin Francesco Mazzarotto Doris Škorić-Milosavljević Christian Krijger Elena Arbelo Dominique Babuty Hector Barajas-Martinez Britt M Beckmann Stéphane Bézieau J Martijn Bos Jeroen Breckpot Oscar Campuzano Silvia Castelletti Candan Celen Sebastian Clauss Anniek Corveleyn Lia Crotti Federica Dagradi Carlo de Asmundis Isabelle Denjoy Sven Dittmann Patrick T Ellinor Cristina Gil Ortuño Carla Giustetto Jean-Baptiste Gourraud Daisuke Hazeki Minoru Horie Taisuke Ishikawa Hideki Itoh Yoshiaki Kaneko Jørgen K Kanters Hiroki Kimoto Maria-Christina Kotta Ingrid P C Krapels Masahiko Kurabayashi Julieta Lazarte Antoine Leenhardt Bart L Loeys Catarina Lundin Takeru Makiyama Jacques Mansourati Raphaël P Martins Andrea Mazzanti Stellan Mörner Carlo Napolitano Kimie Ohkubo Michael Papadakis Boris Rudic Maria Sabater Molina Frédéric Sacher Hatice Sahin Georgia Sarquella-Brugada Regina Sebastiano Sanjay Sharma Mary N Sheppard Keiko Shimamoto M Benjamin Shoemaker Birgit Stallmeyer Johannes Steinfurt Yuji Tanaka David J Tester Keisuke Usuda Paul A van der Zwaag Sonia Van Dooren Lut Van Laer Annika Winbo Bo G Winkel Kenichiro Yamagata Sven Zumhagen Paul G A Volders Steven A Lubitz Charles Antzelevitch Pyotr G Platonov Katja E Odening Dan M Roden Jason D Roberts Jonathan R Skinner Jacob Tfelt-Hansen Maarten P van den Berg Morten S Olesen Pier D Lambiase Martin Borggrefe Kenshi Hayashi Annika Rydberg Tadashi Nakajima Masao Yoshinaga Johan B Saenen Stefan Kääb Pedro Brugada Tomas Robyns Daniela F Giachino Michael J Ackerman Ramon Brugada Josep Brugada Juan R Gimeno Can Hasdemir Pascale Guicheney Silvia G Priori Eric Schulze-Bahr Naomasa Makita Peter J Schwartz Wataru Shimizu Takeshi Aiba Jean-Jacques Schott Richard Redon Seiko Ohno Vincent Probst Elijah R Behr Julien Barc Connie R Bezzina

Genet Med 2020 Sep 7. Epub 2020 Sep 7.

Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/s41436-020-00946-5DOI Listing
September 2020

POPDC2 a novel susceptibility gene for conduction disorders.

J Mol Cell Cardiol 2020 Aug 11;145:74-83. Epub 2020 Jun 11.

Institute for Physiology and Pathophysiology, Vegetative Physiology and Marburg Center for Mind, Brain and Behavior MCMBB, Philipps-University of Marburg, Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2020.06.005DOI Listing
August 2020

An autoantibody profile detects Brugada syndrome and identifies abnormally expressed myocardial proteins.

Eur Heart J 2020 Aug;41(30):2878-2890

Department of Pediatrics, The Labatt Family Heart Centre and Translational Medicine, The Hospital for Sick Children & Research Institute and the University of Toronto, Room 1725D, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

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http://dx.doi.org/10.1093/eurheartj/ehaa383DOI Listing
August 2020

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome.

Authors:
Najim Lahrouchi Rafik Tadros Lia Crotti Yuka Mizusawa Pieter G Postema Leander Beekman Roddy Walsh Kanae Hasegawa Julien Barc Marko Ernsting Kari L Turkowski Andrea Mazzanti Britt M Beckmann Keiko Shimamoto Ulla-Britt Diamant Yanushi D Wijeyeratne Yu Kucho Tomas Robyns Taisuke Ishikawa Elena Arbelo Michael Christiansen Annika Winbo Reza Jabbari Steven A Lubitz Johannes Steinfurt Boris Rudic Bart Loeys M Ben Shoemaker Peter E Weeke Ryan Pfeiffer Brianna Davies Antoine Andorin Nynke Hofman Federica Dagradi Matteo Pedrazzini David J Tester J Martijn Bos Georgia Sarquella-Brugada Óscar Campuzano Pyotr G Platonov Birgit Stallmeyer Sven Zumhagen Eline A Nannenberg Jan H Veldink Leonard H van den Berg Ammar Al-Chalabi Christopher E Shaw Pamela J Shaw Karen E Morrison Peter M Andersen Martina Müller-Nurasyid Daniele Cusi Cristina Barlassina Pilar Galan Mark Lathrop Markus Munter Thomas Werge Marta Ribasés Tin Aung Chiea C Khor Mineo Ozaki Peter Lichtner Thomas Meitinger J Peter van Tintelen Yvonne Hoedemaekers Isabelle Denjoy Antoine Leenhardt Carlo Napolitano Wataru Shimizu Jean-Jacques Schott Jean-Baptiste Gourraud Takeru Makiyama Seiko Ohno Hideki Itoh Andrew D Krahn Charles Antzelevitch Dan M Roden Johan Saenen Martin Borggrefe Katja E Odening Patrick T Ellinor Jacob Tfelt-Hansen Jonathan R Skinner Maarten P van den Berg Morten Salling Olesen Josep Brugada Ramón Brugada Naomasa Makita Jeroen Breckpot Masao Yoshinaga Elijah R Behr Annika Rydberg Takeshi Aiba Stefan Kääb Silvia G Priori Pascale Guicheney Hanno L Tan Christopher Newton-Cheh Michael J Ackerman Peter J Schwartz Eric Schulze-Bahr Vincent Probst Minoru Horie Arthur A Wilde Michael W T Tanck Connie R Bezzina

Circulation 2020 Jul 20;142(4):324-338. Epub 2020 May 20.

Amsterdam UMC, University of Amsterdam, Heart Center; Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, The Netherlands (N.L., R.T., Y.M., P.G.P., L.B., R.W., N.H., H.L.T., A.A.W., C.R.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382531PMC
July 2020

SARS-CoV-2, COVID-19, and inherited arrhythmia syndromes.

Heart Rhythm 2020 09 31;17(9):1456-1462. Epub 2020 Mar 31.

Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam, The Netherlands; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-Heart). Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2020.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156157PMC
September 2020

Arrhythmogenic right ventricular cardiomyopathy : Evolving from unique clinical features to a complex pathophysiological concept.

Herz 2020 May;45(3):243-251

Institute for Genetics of Heart Diseases (IfGH), Division of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1007/s00059-020-04907-1DOI Listing
May 2020

An International Multicenter Evaluation of Type 5 Long QT Syndrome: A Low Penetrant Primary Arrhythmic Condition.

Circulation 2020 02 16;141(6):429-439. Epub 2020 Jan 16.

Department of Cardiovascular Medicine, Division of Heart Rhythm Services, Department of Pediatric and Adolescent Medicine, Division of Pediatric Cardiology, Department of Molecular Pharmacology & Experimental Therapeutics, Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, MN (M.B., J.R.G., M.J.A.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.043114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035205PMC
February 2020

Data on the role of cardiac α-actin (ACTC1) gene mutations on SRF-signaling.

Data Brief 2020 Feb 2;28:105071. Epub 2020 Jan 2.

Department of Internal Medicine III, Cardiology and Angiology, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1016/j.dib.2019.105071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950782PMC
February 2020

A cardiac α-actin (ACTC1) p. Gly247Asp mutation inhibits SRF-signaling in vitro in neonatal rat cardiomyocytes.

Biochem Biophys Res Commun 2019 10 18;518(3):500-505. Epub 2019 Aug 18.

Department of Internal Medicine III, Cardiology and Angiology, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.08.081DOI Listing
October 2019

Cardiac α-Actin (ACTC1) Gene Mutation Causes Atrial-Septal Defects Associated With Late-Onset Dilated Cardiomyopathy.

Circ Genom Precis Med 2019 08 20;12(8):e002491. Epub 2019 Aug 20.

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine (C.F., S.D., B.S., Ellen Schulze-Bahr, S.P., G.S., A.U., Eric Schulze-Bahr), University Hospital Münster.

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http://dx.doi.org/10.1161/CIRCGEN.119.002491DOI Listing
August 2019

Familial Sinus Node Disease Caused by a Gain of GIRK (G-Protein Activated Inwardly Rectifying K Channel) Channel Function.

Circ Genom Precis Med 2019 01;12(1):e002238

Department of Cardiovascular Medicine, Institute for Genetics of Heart Diseases (IfGH), University Hospital Münster, Germany (J.K., B.S., S.Z., G.S., E.S.-B.).

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https://www.ahajournals.org/doi/10.1161/CIRCGEN.118.002238
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http://dx.doi.org/10.1161/CIRCGEN.118.002238DOI Listing
January 2019

In Vitro Analyses of Novel HCN4 Gene Mutations.

Cell Physiol Biochem 2018 7;49(3):1197-1207. Epub 2018 Sep 7.

Myocellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1159/000493301DOI Listing
October 2018

Nonsynonymous TNNI3K mutations and phenotypes: More than a "simple" cardiomyopathy.

Heart Rhythm 2019 01 29;16(1):106-107. Epub 2018 Jul 29.

Institute for Genetics of Heart Diseases (IfGH), University Hospital Münster, Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.07.033DOI Listing
January 2019

SCN10A-Dependent Late I Current: Never Too Late for Cardiac Conduction?

Circ Genom Precis Med 2018 05;11(5):e002167

Institute for Genetics of Heart Diseases, University Hospital Münster, Germany (E.S.-B.).

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http://dx.doi.org/10.1161/CIRCGEN.118.002167DOI Listing
May 2018

Impact of presynaptic sympathetic imbalance in long-QT syndrome by positron emission tomography.

Heart 2018 02 1;104(4):332-339. Epub 2017 Sep 1.

Department of Cardiovascular Medicine, Institute for Genetics of Heart Diseases (IfGH), University Hospital Münster, Münster, Germany.

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2017-311667
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http://dx.doi.org/10.1136/heartjnl-2017-311667DOI Listing
February 2018

(Tpeak - Tend)/QRS and (Tpeak - Tend)/(QT × QRS) as risk markers in Brugada syndrome: authors' reply.

Europace 2017 04;19(4):696-697

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Gebäude D3, Münster D-48149, Germany.

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http://dx.doi.org/10.1093/europace/euw210DOI Listing
April 2017

A Mutation in the G-Protein Gene Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction.

Circ Res 2017 May 20;120(10):e33-e44. Epub 2017 Feb 20.

From the Institute for Genetics of Heart Diseases, Department of Cardiology and Angiology, University Hospital Muenster, Germany (B.S., J.K., S.Z., C.F., E.S.-B., G.S., E.S.-B.); Department of Pediatric Cardiology (S.K.) and Department of General Pediatrics (S.R.), University Children's Hospital Muenster, Germany; and Institute for Physiology and Pathophysiology, Vegetative Physiology, Philipps University of Marburg, Germany (K.V., S.R., L.A.M., N.D.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310112DOI Listing
May 2017

Tpeak-Tend interval and Tpeak-Tend/QT ratio in patients with Brugada syndrome.

Europace 2016 Dec 3;18(12):1866-1872. Epub 2016 Mar 3.

Department of Cardiovascular Medicine, Institute for Genetics of Heart Diseases (IfGH), University Hospital Münster, Albert-Schweitzer-Campus 1, Gebäude D3, D-48149 Münster, Germany.

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http://dx.doi.org/10.1093/europace/euw033DOI Listing
December 2016

Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction.

Basic Res Cardiol 2016 Mar 23;111(2):14. Epub 2016 Jan 23.

Human Stem Cell Pluripotency Group, Max Planck Institute for Molecular Biomedicine, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00395-016-0530-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724360PMC
March 2016

NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes.

Front Cell Neurosci 2015 6;9:387. Epub 2015 Oct 6.

Department of Cardiovascular Medicine, Institute for Genetics of Heart Diseases (IfGH), University Hospital Muenster Muenster, Germany.

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http://dx.doi.org/10.3389/fncel.2015.00387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594022PMC
October 2015

[Molecular diagnosis for cardiovascular diseases].

Dtsch Med Wochenschr 2015 Oct 7;140(20):1538. Epub 2015 Oct 7.

Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum und Technische Universität München, Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Munich Heart Alliance, München.

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http://dx.doi.org/10.1055/s-0041-106132DOI Listing
October 2015

A Common Mutation of Long QT Syndrome Type 1 in Japan.

Circ J 2015 29;79(9):2026-30. Epub 2015 Jun 29.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-15-0342DOI Listing
May 2016

Cardiovascular disease and sudden cardiac death: between genetics and genomics.

Eur Heart J 2015 Jul 8;36(26):1643-5. Epub 2015 May 8.

Institute for Genetics of Heart Diseases (IFGH), Department of Cardiovascular Medicine, University Hospital Münster, Germany Interdisciplinary Center for Clinical Research (IZKF), University Hospital Münster, Germany Collaborative Research Centre 656 'Molecular Cardiovascular Imaging' of the University of Münster, Germany

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http://eurheartj.oxfordjournals.org/content/ehj/early/2015/0
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http://eurheartj.oxfordjournals.org/lookup/doi/10.1093/eurhe
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http://dx.doi.org/10.1093/eurheartj/ehv173DOI Listing
July 2015

Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2.

Circ Cardiovasc Genet 2015 Jun 3;8(3):447-456. Epub 2015 Mar 3.

Department of Clinical and Experimental Cardiology (I.C.R.M.K., P.G.P., J.B., T.T.K., A.A.M.W., C.R.B.), Department of Clinical Epidemiology, Biostatistics and Bioinformatics (I.C.R.M.K., M.W.T.T.), and Department of Clinical Genetics (N.H.), Academic Medical Center, Amsterdam, the Netherlands; ICIN (Netherlands Heart Institute) (J.B., A.A.M.W., C.R.B.), Utrecht, the Netherlands; Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, L'Institut du Thorax, Nantes, France (J.B., J.-J.S.); Centre National de la Recherche Scientifique (CNRS) UMR 6291, Nantes, France (J.B., J.-J.S.); Université de Nantes, Nantes, France (J.B., J.-J.S.); Department of Medicine I, University Hospital Munich, Campus Grosshadern and Innenstadt, Ludwig-Maximilians University, Munich, Germany (M.F.S., B.M.B., S.K.); German Center for Cardiovascular Research (DZHK), Munich Heart Alliance, Munich, Germany (S.K.T.M.); Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany (S.Z., A.H., B.S., E.S.-B.); Interdisciplinary Centre for Clinical Research (IZKF) of the University of Münster, Münster, Germany (S.Z., A.H., B.S., E.S.-B.); Institute of Bioinformatics and Systems Biology (A.P.), and Institute of Human Genetics (A.P., P.L., T.M.), Helmholtz Zentrum München, Neuherberg, Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany (A.P., P.L., T.M.); Department of Medicine (R.J.M., N.H.B.), Department of Molecular and Cellular Pharmacology (R.J.M., N.H.B.), and Hussmann Institute of Human Genomics (R.J.M., N.H.B.), University of Miami Miller School of Medicine, FL; Department of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, TN (D.M.R.); Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, Jeddah, Kingdom of Saudi Arabia (A.A.M.W.); and Centre Hospitalier Universitaire (CHU) Nantes, L'Institut du Thorax, Service de Cardiologie, Nantes, France (J.-J.S.).

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770255PMC
June 2015

TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes.

J Mol Cell Cardiol 2015 Apr 2;81:71-80. Epub 2015 Feb 2.

Institut für Physiologie und Pathophysiologie, Abteilung vegetative Physiologie, Universität Marburg, 35037 Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.01.017DOI Listing
April 2015

Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome.

J Mol Cell Cardiol 2015 Mar 26;80:186-95. Epub 2015 Jan 26.

Institute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University of Marburg, Deutschhausstr. 1-2, 35037 Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.01.002DOI Listing
March 2015

First report on an inotropic peptide activating tetrodotoxin-sensitive, "neuronal" sodium currents in the heart.

Circ Heart Fail 2015 Jan 25;8(1):79-88. Epub 2014 Nov 25.

From the Department of Cardiovascular Medicine (P.K., L.F., S.N., L.F.), Department of Pharmacology and Toxicology (J.K., J.S.S., F.U.M., W.S., U.K.), and Department of Cardiovascular Medicine, Institute for Genetics of Heart Disease (IfGH) (B.S., E.S.-B.), Hospital of the University of Muenster, Muenster, Germany; Center for Cardiovascular Sciences, School of Clinical and Experimental Medicine, and SWBH NHS Trust, University of Birmingham, Birmingham, United Kingdom (P.K., L.F.); Technion Israel Institute of Technology, Haifa, Israel (T.T.); Department of Animal and Cell Biology, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel (T.T., N.N., E.Z.); Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic (J.K.); Department of Neurology, and Division of Neuropathophysiology, Institute of Physiology I (P.E.) and Institute of Physiology I (T.K., T.B.), University of Muenster, Muenster, Germany; and Department of Clinical and Interventional Angiology, Asklepios Clinic St. Georg, Hamburg, Germany (S.N.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.113.001066DOI Listing
January 2015

The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias.

Pflugers Arch 2015 May 19;467(5):1055-67. Epub 2014 Nov 19.

Institut für Physiologie und Pathophysiologie, Vegetative Physiologie, Philipps-Universität Marburg, Deutschhausstraße 2, 35037, Marburg, Germany,

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http://dx.doi.org/10.1007/s00424-014-1637-5DOI Listing
May 2015

Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A).

Pflugers Arch 2014 Oct 5;466(10):1885-97. Epub 2014 Jan 5.

Institute for Genetics of Heart Diseases (IfGH), -Myocellular Electrophysiology, Department of Cardiovascular Medicine, University Hospital Muenster, 48149, Muenster, Germany.

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http://dx.doi.org/10.1007/s00424-013-1424-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159565PMC
October 2014

Cardiac sympathetic innervation in a patient with catecholaminergic polymorphic ventricular tachycardia.

Heart Rhythm 2014 Aug 22;11(8):1490-1. Epub 2013 Oct 22.

Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2013.10.037DOI Listing
August 2014

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

Nat Genet 2013 Sep 21;45(9):1044-9. Epub 2013 Jul 21.

Department of Clinical and Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.2712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869788PMC
September 2013

A common structural component for β-subunit mediated modulation of slow inactivation in different KV channels.

Cell Physiol Biochem 2013 26;31(6):968-80. Epub 2013 Jun 26.

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1159/000350115DOI Listing
February 2014

Coxsackievirus B3 modulates cardiac ion channels.

FASEB J 2013 Oct 27;27(10):4108-21. Epub 2013 Jun 27.

2Institut für Genetik von Herzerkrankungen (IfGH), Abteilung Myozelluläre Elektrophysiologie, Albert-Schweitzer-Campus 1 (Gebäude D3), D-48149 Münster.

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http://dx.doi.org/10.1096/fj.13-230193DOI Listing
October 2013

Non dominant-negative KCNJ2 gene mutations leading to Andersen-Tawil syndrome with an isolated cardiac phenotype.

Basic Res Cardiol 2013 May 5;108(3):353. Epub 2013 May 5.

Institut für Physiologie und Pathophysiologie, Vegetative Physiologie, Philipps-University Marburg, Deutschhausstraße 1-2, 35037 Marburg, Germany.

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http://dx.doi.org/10.1007/s00395-013-0353-1DOI Listing
May 2013

Connexin expression patterns in arrhythmogenic right ventricular cardiomyopathy.

Am J Cardiol 2013 May 29;111(10):1488-95. Epub 2013 Mar 29.

Division of Cardiology, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1016/j.amjcard.2013.01.299DOI Listing
May 2013

Inherited long QT syndrome: clinical manifestation, genetic diagnostics, and therapy.

Herzschrittmacherther Elektrophysiol 2012 Sep 21;23(3):211-9. Epub 2012 Sep 21.

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Gebäude D3, 48149, Münster, Germany.

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http://link.springer.com/10.1007/s00399-012-0232-8
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http://dx.doi.org/10.1007/s00399-012-0232-8DOI Listing
September 2012

Arrhythmia-associated cardiac Ca²(+) cycling proteins and gene mutations.

Wien Med Wochenschr 2012 Jul 25;162(13-14):292-6. Epub 2012 Jun 25.

Division of Experimental and Clinical Electrophysiology,Department of Cardiology and Angiology,University Hospital Münster,Albert-Schweitzer-Campus 1 (Gebäude A1),48149 Muenster, Germany.

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http://dx.doi.org/10.1007/s10354-012-0114-zDOI Listing
July 2012

Overlapping cardiac phenotype associated with a familial mutation in the voltage sensor of the KCNQ1 channel.

Cell Physiol Biochem 2012 11;29(5-6):809-18. Epub 2012 May 11.

Biochemistry I - Cation Channel Group, Ruhr University Bochum, Bochum, Germany.

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http://dx.doi.org/10.1159/000178470DOI Listing
November 2012

Guiding the molecular diagnosis of hypertrophic cardiomyopathy.

J Thorac Cardiovasc Surg 2012 May;143(5):1234

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http://dx.doi.org/10.1016/j.jtcvs.2012.01.062DOI Listing
May 2012

Identification of novel mutations in LMNA associated with familial forms of dilated cardiomyopathy.

Genet Test Mol Biomarkers 2012 Jun 6;16(6):543-9. Epub 2012 Jan 6.

Institut für Genetik von Herzerkrankungen (IfGH), Universitätsklinik Münster, Münster, Germany.

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http://dx.doi.org/10.1089/gtmb.2011.0214DOI Listing
June 2012

Microvascular dysfunction in nonfailing arrhythmogenic right ventricular cardiomyopathy.

Eur J Nucl Med Mol Imaging 2012 Mar 24;39(3):416-20. Epub 2011 Nov 24.

Department of Cardiology and Angiology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1007/s00259-011-1985-8DOI Listing
March 2012

Role of implantable cardioverter defibrillator therapy in patients with acquired long QT syndrome: a long-term follow-up.

Europace 2012 Mar 6;14(3):396-401. Epub 2011 Oct 6.

Department of Cardiology and Angiology, Division of Experimental and Clinical Electrophysiology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1093/europace/eur316DOI Listing
March 2012

Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome.

Eur J Nucl Med Mol Imaging 2011 Oct 21;38(10):1899-907. Epub 2011 Jun 21.

Department of Nuclear Medicine, University Hospital Münster, and Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany.

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October 2011

Totally subcutaneous implantable cardioverter defibrillator with an alternative, right parasternal, electrode placement.

Pacing Clin Electrophysiol 2012 Sep 14;35(9):e254-7. Epub 2011 Mar 14.

Institute for Genetics of Heart Diseases, University Hospital Münster, Münster, Germany.

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September 2012

Successful treatment of catecholaminergic polymorphic ventricular tachycardia with flecainide: a case report and review of the current literature.

Europace 2011 Jun 2;13(6):897-901. Epub 2011 Feb 2.

Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer Strasse 33, 48149 Münster, Germany.

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http://dx.doi.org/10.1093/europace/euq517DOI Listing
June 2011

Ivabradine in patients with inappropriate sinus tachycardia.

Naunyn Schmiedebergs Arch Pharmacol 2010 Dec 22;382(5-6):483-6. Epub 2010 Sep 22.

Department of Cardiology and Angiology, Hospital of the University of Münster, Münster, Germany.

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December 2010

A homozygous SCN5A mutation in a severe, recessive type of cardiac conduction disease.

Hum Mutat 2010 Aug;31(8):E1609-21

Experimental Neuropediatrics, University Medical Center Hamburg-Eppendorf, Germany.

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http://dx.doi.org/10.1002/humu.21302DOI Listing
August 2010

The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling.

J Mol Cell Cardiol 2010 Jul 17;49(1):95-105. Epub 2010 Mar 17.

Institut für Pharmakologie und Toxikologie, Universitätsklinikum Münster, Domagkstr. 12, 48149 Münster, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2010.03.006DOI Listing
July 2010

Absence of pathognomonic or inflammatory patterns in cardiac biopsies from patients with Brugada syndrome.

Circ Arrhythm Electrophysiol 2009 Feb 7;2(1):16-23. Epub 2008 Dec 7.

Department of Cardiology and Angiology, Hospital of the University of Münster, Münster, Germany.

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http://dx.doi.org/10.1161/CIRCEP.107.737882DOI Listing
February 2009

Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I.

J Clin Invest 2009 Sep 24;119(9):2737-44. Epub 2009 Aug 24.

Institut für Neurale Signalverarbeitung, Zentrum für Molekulare Neurobiologie, Universität Hamburg, Hamburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735920PMC
September 2009

Making sense in a nonsense reading frame: suppression of cardiac sodium channel dysfunction.

Cardiovasc Res 2009 Aug 15;83(3):423-4. Epub 2009 Jun 15.

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http://dx.doi.org/10.1093/cvr/cvp196DOI Listing
August 2009

Genes causing inherited forms of cardiomyopathies. A current compendium.

Herz 2009 Mar;34(2):98-109

Department of Cardiology and Angiology, University Hospital Münster, Münster, Germany.

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March 2009

Susceptibility genes & modifiers for cardiac arrhythmias.

Prog Biophys Mol Biol 2008 Oct-Nov;98(2-3):289-300. Epub 2009 Jan 29.

Leibniz Institute for Arteriosclerosis Research (LIFA), Molecular Cardiology, University of Münster, Germany.

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May 2009

Risk assessment in Brugada-syndrome: the way back to the surface ECG.

J Cardiovasc Electrophysiol 2008 Apr 12;19(4):384-5. Epub 2008 Feb 12.

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April 2008

Cardiac sodium channels: dysregulation meets myocardial failure.

Cardiovasc Res 2007 Aug 19;75(3):455-6. Epub 2007 Jun 19.

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August 2007

Life-threatening hobbies in the youth? Two autoptic cases suggesting arrhythmogenic right ventricular cardiomyopathy.

Forensic Sci Int 2007 Aug 1;171(1):e1-4. Epub 2007 Jun 1.

Institute of Legal Medicine, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.

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August 2007

Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published data.

Eur Heart J 2007 Sep 5;28(17):2126-33. Epub 2007 May 5.

Department of Cardiology and Angiology, University Hospital of Muenster, Albert-Schweitzer-Str. 33, D-48149 Muenster, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehm116DOI Listing
September 2007

The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

Biochem Biophys Res Commun 2007 Jun 27;358(1):304-10. Epub 2007 Apr 27.

Department of Biomedical Sciences, The Danish National Research Foundation Centre for Cardiac Arrhythmia, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.

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June 2007

Sudden cardiac death in Andersen-Tawil syndrome.

Europace 2007 Mar 1;9(3):162-6. Epub 2007 Feb 1.

Klinikum Dorothea Christiane Erxleben Quedlinburg, Academic Teaching Hospital of the University Hospital Magdeburg, Innere Medizin II-Kardiologie, Ditfurter Weg 24, 06484 Quedlinburg, Germany.

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http://dx.doi.org/10.1093/europace/eul188DOI Listing
March 2007

Female predominance and transmission distortion in the long-QT syndrome.

N Engl J Med 2006 Dec;355(26):2744-51

INSERM, Institut de Myologie, Université Pierre et Marie Curie, Institut Fédératif de Recherche 14 and Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1056/NEJMoa042786DOI Listing
December 2006

Genotype-specific onset of arrhythmias in congenital long-QT syndrome: possible therapy implications.

Circulation 2006 Nov 6;114(20):2096-103. Epub 2006 Nov 6.

Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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November 2006

C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.

Hum Mol Genet 2006 Oct 21;15(19):2888-902. Epub 2006 Aug 21.

Institute for Neural Signal Transduction, ZMNH, Department of Pediatrics, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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October 2006

Electrocardiographic risk stratification in families with congenital long QT syndrome.

Eur Heart J 2006 Sep 1;27(17):2074-80. Epub 2006 Aug 1.

Department of Cardiology and Angiology, Medizinische Klinik und Poliklinik C, University Hospital Münster, Albert-Schweitzer-Str. 33, D-48149 Münster, Germany.

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September 2006

Mutation detection beyond: an example from congenital long QT syndrome.

Heart Rhythm 2006 Jul 6;3(7):822-3. Epub 2006 Apr 6.

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July 2006

[Short QT Syndromes].

Herz 2006 Apr;31(2):118-22; quiz 142-3

Medizinische Klinik und Poliklinik C (Kardiologie und Angiologie), Universitätsklinikum Münster (UKM), Münster.

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April 2006