Eric Orwoll

Eric Orwoll

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Eric Orwoll

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Association of dietary patterns with the gut microbiota in older, community-dwelling men.

Am J Clin Nutr 2019 Oct;110(4):1003-1014

Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1093/ajcn/nqz174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766444PMC
October 2019

Association of change in muscle mass assessed by D -creatine dilution with changes in grip strength and walking speed.

J Cachexia Sarcopenia Muscle 2019 Oct 17. Epub 2019 Oct 17.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/jcsm.12494DOI Listing
October 2019

Proteomic studies of bone and skeletal health outcomes.

Bone 2019 Sep 4;126:18-26. Epub 2019 Apr 4.

Oregon Health & Science University, Portland, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.03.032DOI Listing
September 2019

The Relationships Between Physical Performance, Activity Levels, and Falls in Older Men.

J Gerontol A Biol Sci Med Sci 2019 Aug;74(9):1475-1483

Department of Biostatistics, School of Public Health and the Biostatistics and Design Program, Oregon Health & Science University, Portland.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/gly248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696710PMC
August 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 08 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Alterations in non-type I collagen biomarkers in osteogenesis imperfecta.

Bone 2019 03 2;120:70-74. Epub 2018 Oct 2.

Department of Medicine, Division of Endocrinology, Oregon Health & Science University, Portland, OR, United States of America.

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https://linkinghub.elsevier.com/retrieve/pii/S87563282183036
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http://dx.doi.org/10.1016/j.bone.2018.09.024DOI Listing
March 2019

Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 02;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

D -Creatine dilution and the importance of accuracy in the assessment of skeletal muscle mass.

J Cachexia Sarcopenia Muscle 2019 02 21;10(1):14-21. Epub 2019 Mar 21.

California Pacific Medical Center, Research Institute, University of San Francisco, USA.

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http://dx.doi.org/10.1002/jcsm.12390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438329PMC
February 2019

Association of High-resolution Peripheral Quantitative Computed Tomography (HR-pQCT) bone microarchitectural parameters with previous clinical fracture in older men: The Osteoporotic Fractures in Men (MrOS) study.

Bone 2018 08 8;113:49-56. Epub 2018 May 8.

Center for Chronic Disease Outcomes Research, Veterans Affairs Health Care System, Minneapolis, MN, USA; Department of Medicine, University of Minnesota, Minneapolis, MN, USA; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S87563282183018
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http://dx.doi.org/10.1016/j.bone.2018.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040812PMC
August 2018

The importance of the circadian system & sleep for bone health.

Metabolism 2018 07 9;84:28-43. Epub 2017 Dec 9.

Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, USA; OHSU-PSU School of Public Health, Portland, OR, USA.

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http://dx.doi.org/10.1016/j.metabol.2017.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994176PMC
July 2018

Comparison of Associations of DXA and CT Visceral Adipose Tissue Measures With Insulin Resistance, Lipid Levels, and Inflammatory Markers.

J Clin Densitom 2017 Apr - Jun;20(2):256-264. Epub 2017 Feb 24.

Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN; Department of Medicine, University of Minnesota, Minneapolis, MN, USA; Center for Chronic Disease Outcomes Research, Minneapolis VA Health Care System, Minneapolis, MN, USA.

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http://dx.doi.org/10.1016/j.jocd.2017.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560438PMC
June 2018

Serum Sodium and Cognition in Older Community-Dwelling Men.

Clin J Am Soc Nephrol 2018 03 8;13(3):366-374. Epub 2018 Feb 8.

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

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http://dx.doi.org/10.2215/CJN.07400717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967671PMC
March 2018

Serum Sclerostin Levels in Adults With Osteogenesis Imperfecta: Comparison With Normal Individuals and Response to Teriparatide Therapy.

J Bone Miner Res 2018 02 7;33(2):307-315. Epub 2017 Dec 7.

Department of Medicine, Division of Endocrinology, Oregon Health & Sciences University, Portland, OR, USA.

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http://dx.doi.org/10.1002/jbmr.3312DOI Listing
February 2018

Vertebral Fracture Risk in Diabetic Elderly Men: The MrOS Study.

J Bone Miner Res 2018 01 27;33(1):63-69. Epub 2017 Dec 27.

Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/jbmr.3287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702944PMC
January 2018

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

Am J Hum Genet 2018 01;102(1):88-102

Department of Internal Medicine, Erasmus MC, 3000 CA Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC, 3000 CA Rotterdam, the Netherlands; Department of Epidemiology, Erasmus MC, 3000 CA Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777980PMC
January 2018

Rest-activity circadian rhythms and bone mineral density in elderly men.

Bone Rep 2017 Dec 10;7:156-163. Epub 2017 Nov 10.

Center for Musculoskeletal Health, University of California, Davis Medical Center, 4625 2nd Avenue, Suite 2000, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1016/j.bonr.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695538PMC
December 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans.

J Clin Endocrinol Metab 2017 10;102(10):3722-3730

Division of Endocrinology and Bone and Mineral Unit, Oregon Health & Science University, Portland, Oregon 97239.

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http://dx.doi.org/10.1210/jc.2017-01147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630251PMC
October 2017

and Loci Associate with Plasma Osmolality.

Authors:
Carsten A Böger Mathias Gorski Gearoid M McMahon Huichun Xu Yen-Pei C Chang Peter J van der Most Gerjan Navis Ilja M Nolte Martin H de Borst Weihua Zhang Benjamin Lehne Marie Loh Sian-Tsung Tan Eric Boerwinkle Morgan E Grams Peggy Sekula Man Li Beth Wilmot James G Moon Paul Scheet Francesco Cucca Xiangjun Xiao Leo-Pekka Lyytikäinen Graciela Delgado Tanja B Grammer Marcus E Kleber Sanaz Sedaghat Fernando Rivadeneira Tanguy Corre Zoltan Kutalik Sven Bergmann Carrie M Nielson Priya Srikanth Alexander Teumer Martina Müller-Nurasyid Anne Catharina Brockhaus Arne Pfeufer Wolfgang Rathmann Annette Peters Martha Matsumoto Mariza de Andrade Elizabeth J Atkinson Cassianne Robinson-Cohen Ian H de Boer Shih-Jen Hwang Iris M Heid Martin Gögele Maria Pina Concas Toshiko Tanaka Stefania Bandinelli Mike A Nalls Andrew Singleton Salman M Tajuddin Adebowale Adeyemo Jie Zhou Ayo Doumatey Shannon McWeeney Joanne Murabito Nora Franceschini Michael Flessner Michael Shlipak James G Wilson Guanjie Chen Charles N Rotimi Alan B Zonderman Michele K Evans Luigi Ferrucci Olivier Devuyst Mario Pirastu Alan Shuldiner Andrew A Hicks Peter Paul Pramstaller Bryan Kestenbaum Sharon L R Kardia Stephen T Turner LifeLines Cohort Study Tamara Ellefson Briske Christian Gieger Konstantin Strauch Christa Meisinger Thomas Meitinger Uwe Völker Matthias Nauck Henry Völzke Peter Vollenweider Murielle Bochud Gerard Waeber Mika Kähönen Terho Lehtimäki Winfried März Abbas Dehghan Oscar H Franco Andre G Uitterlinden Albert Hofman Herman A Taylor John C Chambers Jaspal S Kooner Caroline S Fox Robert Hitzemann Eric S Orwoll Cristian Pattaro David Schlessinger Anna Köttgen Harold Snieder Afshin Parsa David M Cohen

J Am Soc Nephrol 2017 Aug 30;28(8):2311-2321. Epub 2017 Mar 30.

Due to the number of contributing authors, the affiliations are listed in the supplemental material.

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http://dx.doi.org/10.1681/ASN.2016080892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533231PMC
August 2017

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Am J Hum Genet 2017 Aug 27;101(2):227-238. Epub 2017 Jul 27.

Department of Human Genetics, McGill University, Montreal, QC H3A 1B1, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK; Department of Medicine, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544392PMC
August 2017

Cystatin C and the Risk of Frailty and Mortality in Older Men.

J Gerontol A Biol Sci Med Sci 2017 Jul;72(7):965-970

Department of Medicine, University of Minnesota, Minneapolis.

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http://dx.doi.org/10.1093/gerona/glw223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458398PMC
July 2017

Actigraphy- and Polysomnography-Measured Sleep Disturbances, Inflammation, and Mortality Among Older Men.

Psychosom Med 2016 Jul-Aug;78(6):686-96

From the Department of Epidemiology, Graduate School of Public Health (Smagula, Cauley), and Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center (Smagula, Cauley), University of Pittsburgh, Pittsburgh, Pennsylvania; Research Institute (Stone), California Pacific Medical Center, San Francisco, California; Division of Sleep Medicine (Redline), Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Boston, Massachusetts; Departments of Psychiatry and Medicine (Ancoli-Israel) and Family and Preventive Medicine, Division of Epidemiology (Barrett-Connor), University of California San Diego, La Jolla, California; Department of Veterans Affairs San Diego Center of Excellence for Stress and Mental Health (CESAMH; Ancoli-Israel), San Diego, California; Aging Center, Medicine and Rheumatology (Lane), University of California at Davis School of Medicine, Sacramento, CA; Division of Endocrinology, Diabetes, and Clinical Nutrition, Department of Medicine (Orwoll), Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.1097/PSY.0000000000000312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765903PMC
July 2017

Older Men With Anemia Have Increased Fracture Risk Independent of Bone Mineral Density.

J Clin Endocrinol Metab 2017 07;102(7):2199-2206

Division of Endocrinology, Stanford University School of Medicine, Stanford, California 94305.

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http://dx.doi.org/10.1210/jc.2017-00266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505193PMC
July 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study.

J Bone Miner Res 2017 Jun 27;32(6):1174-1181. Epub 2017 Feb 27.

Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/jbmr.3088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466469PMC
June 2017

Clinical Practice Guidelines for Osteoporosis: Translating Data to Patients?

Authors:
Eric S Orwoll

Ann Intern Med 2017 06 9;166(11):852-853. Epub 2017 May 9.

From Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.7326/M17-0957DOI Listing
June 2017

Trajectories of the relationships of physical activity with body composition changes in older men: the MrOS study.

BMC Geriatr 2017 06 5;17(1):119. Epub 2017 Jun 5.

Stanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1186/s12877-017-0506-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460414PMC
June 2017

Predictors of non-vertebral fracture in older Chinese males and females: Mr. OS and Ms. OS (Hong Kong).

J Bone Miner Metab 2017 May 25;35(3):330-337. Epub 2016 May 25.

Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

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http://dx.doi.org/10.1007/s00774-016-0761-zDOI Listing
May 2017

Rest-activity patterns and falls and fractures in older men.

Osteoporos Int 2017 04 24;28(4):1313-1322. Epub 2016 Dec 24.

California Pacific Medical Center Research Institute, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s00198-016-3874-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533275PMC
April 2017

Further Elucidation of the Potential Benefits of Testosterone Therapy in Older Men.

Authors:
Eric Orwoll

JAMA Intern Med 2017 04;177(4):459-460

Oregon Health & Science University, Portland.

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http://dx.doi.org/10.1001/jamainternmed.2016.9576DOI Listing
April 2017

Harmonized Reference Ranges for Circulating Testosterone Levels in Men of Four Cohort Studies in the United States and Europe.

J Clin Endocrinol Metab 2017 04;102(4):1161-1173

Research Program in Men's Health, Aging, and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-2935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460736PMC
April 2017

Bone Density Loss Is Associated With Blood Cell Counts.

J Bone Miner Res 2017 Feb 2;32(2):212-220. Epub 2016 Nov 2.

Division of Endocrinology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1002/jbmr.3000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292053PMC
February 2017

Areal and volumetric bone mineral density and risk of multiple types of fracture in older men.

Bone 2016 11 20;92:100-106. Epub 2016 Aug 20.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056840PMC
http://dx.doi.org/10.1016/j.bone.2016.08.014DOI Listing
November 2016

Association of 3D Geometric Measures Derived From Quantitative Computed Tomography With Hip Fracture Risk in Older Men.

J Bone Miner Res 2016 08 4;31(8):1550-8. Epub 2016 May 4.

Sektion Biomedizinische Bildgebung, Klinik für Radiologie und Neuroradiologie, Universitätsklinikum Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1002/jbmr.2821DOI Listing
August 2016

Lower Urinary Tract Symptoms and Risk of Nonspine Fractures among Older Community Dwelling U.S. Men.

J Urol 2016 07 22;196(1):166-72. Epub 2016 Feb 22.

Division of Urologic Oncology, Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, California; Division of Urology, San Diego Veterans Affairs Medical Center, La Jolla, California.

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http://dx.doi.org/10.1016/j.juro.2016.02.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914455PMC
July 2016

Association of urinary melatonin levels and aging-related outcomes in older men.

Sleep Med 2016 07 4;23:73-80. Epub 2016 Aug 4.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, USA; Department of Epidemiology, H.T. Chan Harvard School of Public Health, USA; Department of Epidemiology, Center for Public Health, Medical University of Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074554PMC
http://dx.doi.org/10.1016/j.sleep.2016.07.006DOI Listing
July 2016

Time to Osteoporosis and Major Fracture in Older Men: The MrOS Study.

Am J Prev Med 2016 06 25;50(6):727-736. Epub 2016 Jan 25.

Department of Medicine, University of Minnesota, Minneapolis, Minnesota; Center for Chronic Disease Outcomes Research, VA Health Care System, Minneapolis, Minnesota; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.amepre.2015.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875888PMC
June 2016

Passing the Baton--Harnessing the Full Value of Older Scientists.

Authors:
Eric Orwoll

N Engl J Med 2016 Jun;374(26):2514-7

From Oregon Health and Science University, Portland.

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http://dx.doi.org/10.1056/NEJMp1603666DOI Listing
June 2016

Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations.

J Clin Endocrinol Metab 2016 05 23;101(5):2226-34. Epub 2016 Mar 23.

Bone & Mineral Unit (C.M.N., Y.W., C.M.S., E.S.O.), Oregon Health & Science University, Portland, Oregon 97239; School of Public Health (C.M.N., J.L.), Oregon Health & Science University, Portland, Oregon 97239; Medical Research Council Human Nutrition Research (K.S.J., A.P., I.S.), Cambridge, UK CB1 9NL; Department of Orthopedics (R.F.C.), University of California, Los Angeles, California 90095; Pacific Northwest National Laboratory (J.M.J., R.D.S., T.S., Y.G., A.A.S.), Richland, Washington 99354; Institute of Metabolism and Systems Research (M.H.), University of Birmingham, Birmingham, UK B15 2TT; University of California (J.S.A.), Los Angeles, California 90095; School of Medicine (C.M.S., C.G.L., E.S.O.), Oregon Health & Science University, Portland, Oregon 97239; Portland Veterans Affairs Medical Center (C.G.L.), Oregon 97239; Laboratory of Diagnostic Medicine (D.V.), KU Leuven, 3000 Belgium; Laboratory of Clinical and Experimental Endocrinology (D.V., R.B.), KU Leuven, 3000 Belgium; Department of Cardiovascular Sciences (S.P.), KU Leuven, Belgium 3000; Department of Laboratory Medicine (S.P.), University Hospitals Leuven, 3000 Belgium; MRC Keneba (A.P.), Keneba, The Gambia; and Department of Epidemiology (J.M.Z., J.A.C.), University of Pittsburgh, Pennsylvania 15261.

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http://dx.doi.org/10.1210/jc.2016-1104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870848PMC
May 2016

Associations of Body Mass Index With Incident Fractures and Hip Structural Parameters in a Large Canadian Cohort.

J Clin Endocrinol Metab 2016 Feb 15;101(2):476-84. Epub 2015 Dec 15.

Department of Medicine (J.S., C.M.N., E.S.O.), Bone and Mineral Unit, Oregon Health & Science University, Portland, Oregon 97239; University of Manitoba (W.D.L.), Winnipeg, Canada R3T 2N2; University of Alberta (S.R.M.), Edmonton, Alberta, Canada T6G 2H7; and McGill University (S.N.M.), Montreal, Québec, Canada H9X 3V9.

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http://dx.doi.org/10.1210/jc.2015-3123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393587PMC
February 2016

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

Authors:
Yingchang Lu Felix R Day Stefan Gustafsson Martin L Buchkovich Jianbo Na Veronique Bataille Diana L Cousminer Zari Dastani Alexander W Drong Tõnu Esko David M Evans Mario Falchi Mary F Feitosa Teresa Ferreira Åsa K Hedman Robin Haring Pirro G Hysi Mark M Iles Anne E Justice Stavroula Kanoni Vasiliki Lagou Rui Li Xin Li Adam Locke Chen Lu Reedik Mägi John R B Perry Tune H Pers Qibin Qi Marianna Sanna Ellen M Schmidt William R Scott Dmitry Shungin Alexander Teumer Anna A E Vinkhuyzen Ryan W Walker Harm-Jan Westra Mingfeng Zhang Weihua Zhang Jing Hua Zhao Zhihong Zhu Uzma Afzal Tarunveer Singh Ahluwalia Stephan J L Bakker Claire Bellis Amélie Bonnefond Katja Borodulin Aron S Buchman Tommy Cederholm Audrey C Choh Hyung Jin Choi Joanne E Curran Lisette C P G M de Groot Philip L De Jager Rosalie A M Dhonukshe-Rutten Anke W Enneman Elodie Eury Daniel S Evans Tom Forsen Nele Friedrich Frédéric Fumeron Melissa E Garcia Simone Gärtner Bok-Ghee Han Aki S Havulinna Caroline Hayward Dena Hernandez Hans Hillege Till Ittermann Jack W Kent Ivana Kolcic Tiina Laatikainen Jari Lahti Irene Mateo Leach Christine G Lee Jong-Young Lee Tian Liu Youfang Liu Stéphane Lobbens Marie Loh Leo-Pekka Lyytikäinen Carolina Medina-Gomez Karl Michaëlsson Mike A Nalls Carrie M Nielson Laticia Oozageer Laura Pascoe Lavinia Paternoster Ozren Polašek Samuli Ripatti Mark A Sarzynski Chan Soo Shin Nina Smolej Narančić Dominik Spira Priya Srikanth Elisabeth Steinhagen-Thiessen Yun Ju Sung Karin M A Swart Leena Taittonen Toshiko Tanaka Emmi Tikkanen Nathalie van der Velde Natasja M van Schoor Niek Verweij Alan F Wright Lei Yu Joseph M Zmuda Niina Eklund Terrence Forrester Niels Grarup Anne U Jackson Kati Kristiansson Teemu Kuulasmaa Johanna Kuusisto Peter Lichtner Jian'an Luan Anubha Mahajan Satu Männistö Cameron D Palmer Janina S Ried Robert A Scott Alena Stancáková Peter J Wagner Ayse Demirkan Angela Döring Vilmundur Gudnason Douglas P Kiel Brigitte Kühnel Massimo Mangino Barbara Mcknight Cristina Menni Jeffrey R O'Connell Ben A Oostra Alan R Shuldiner Kijoung Song Liesbeth Vandenput Cornelia M van Duijn Peter Vollenweider Charles C White Michael Boehnke Yvonne Boettcher Richard S Cooper Nita G Forouhi Christian Gieger Harald Grallert Aroon Hingorani Torben Jørgensen Pekka Jousilahti Mika Kivimaki Meena Kumari Markku Laakso Claudia Langenberg Allan Linneberg Amy Luke Colin A Mckenzie Aarno Palotie Oluf Pedersen Annette Peters Konstantin Strauch Bamidele O Tayo Nicholas J Wareham David A Bennett Lars Bertram John Blangero Matthias Blüher Claude Bouchard Harry Campbell Nam H Cho Steven R Cummings Stefan A Czerwinski Ilja Demuth Rahel Eckardt Johan G Eriksson Luigi Ferrucci Oscar H Franco Philippe Froguel Ron T Gansevoort Torben Hansen Tamara B Harris Nicholas Hastie Markku Heliövaara Albert Hofman Joanne M Jordan Antti Jula Mika Kähönen Eero Kajantie Paul B Knekt Seppo Koskinen Peter Kovacs Terho Lehtimäki Lars Lind Yongmei Liu Eric S Orwoll Clive Osmond Markus Perola Louis Pérusse Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Fernando Rivadeneira Igor Rudan Veikko Salomaa Thorkild I A Sørensen Michael Stumvoll Anke Tönjes Bradford Towne Gregory J Tranah Angelo Tremblay André G Uitterlinden Pim van der Harst Erkki Vartiainen Jorma S Viikari Veronique Vitart Marie-Claude Vohl Henry Völzke Mark Walker Henri Wallaschofski Sarah Wild James F Wilson Loïc Yengo D Timothy Bishop Ingrid B Borecki John C Chambers L Adrienne Cupples Abbas Dehghan Panos Deloukas Ghazaleh Fatemifar Caroline Fox Terrence S Furey Lude Franke Jiali Han David J Hunter Juha Karjalainen Fredrik Karpe Robert C Kaplan Jaspal S Kooner Mark I McCarthy Joanne M Murabito Andrew P Morris Julia A N Bishop Kari E North Claes Ohlsson Ken K Ong Inga Prokopenko J Brent Richards Eric E Schadt Tim D Spector Elisabeth Widén Cristen J Willer Jian Yang Erik Ingelsson Karen L Mohlke Joel N Hirschhorn John Andrew Pospisilik M Carola Zillikens Cecilia Lindgren Tuomas Oskari Kilpeläinen Ruth J F Loos

Nat Commun 2016 Feb 1;7:10495. Epub 2016 Feb 1.

The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/ncomms10495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740398PMC
February 2016

Osteoporosis in men: findings from the Osteoporotic Fractures in Men Study (MrOS).

Ther Adv Musculoskelet Dis 2016 Feb;8(1):15-27

UC Davis Health System, 4625 2nd Avenue, Suite 2006, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1177/1759720X15621227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707416PMC
February 2016

Establishing a Framework--Does Testosterone Supplementation Help Older Men?

Authors:
Eric S Orwoll

N Engl J Med 2016 Feb;374(7):682-3

From the Department of Medicine, Oregon Health and Science University, Portland.

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http://dx.doi.org/10.1056/NEJMe1600196DOI Listing
February 2016

Subclinical Thyroid Dysfunction and Frailty Among Older Men.

J Clin Endocrinol Metab 2015 Dec 23;100(12):4524-32. Epub 2015 Oct 23.

Department of Internal Medicine (V.S.V.), University Hospital of Zürich, 8091 Zürich, Switzerland; Department of General Internal Medicine (N.R.), Inselspital, University Hospital of Bern, 3010 Bern, Switzerland; California Pacific Medical Center Research Institute (L.H.), San Francisco, California 94107; Stanford University Medical School (A.R.H.), Palo Alto, California 94305; Bone and Mineral Unit (E.S.O.), Oregon Health & Science University, Portland, Oregon 97239; Department of Medicine (K.E.E.) and Division of Epidemiology and Community Health (K.E.E.), University of Minnesota, Minneapolis, Minnesota 55455; Center for Chronic Disease Outcomes Research (K.E.E.), Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota 55417; and Departments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California 94143.

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http://dx.doi.org/10.1210/jc.2015-3191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667157PMC
December 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://dx.doi.org/10.1038/nature14878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015

Risk of Nonspine Fractures in Older Adults with Sarcopenia, Low Bone Mass, or Both.

J Am Geriatr Soc 2015 Sep 27;63(9):1733-40. Epub 2015 Aug 27.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1111/jgs.13605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625906PMC
September 2015