Eric McDade

Eric McDade

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That's Inappropriate! Social Norms in an Older Population-based Cohort.

Alzheimer Dis Assoc Disord 2018 Apr-Jun;32(2):150-155

Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/WAD.0000000000000224DOI Listing
September 2019

A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials.

Alzheimers Dement 2019 Sep 7. Epub 2019 Sep 7.

Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Departments of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.06.4955DOI Listing
September 2019

Blood Pressure and Memory: Novel Approaches to Modeling Nonlinear Effects in Longitudinal Studies.

Alzheimer Dis Assoc Disord 2019 Sep 23. Epub 2019 Sep 23.

Departments of Biostatistics.

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http://dx.doi.org/10.1097/WAD.0000000000000346DOI Listing
September 2019

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset.

Alzheimers Dement 2019 Apr 15;15(4):506-514. Epub 2019 Feb 15.

Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461496PMC
April 2019

Why Amyloid Is Still a Target for Alzheimer Disease Clinical Trials.

Authors:
Eric McDade

J Am Geriatr Soc 2019 Apr 9;67(4):845-847. Epub 2019 Mar 9.

Department of Neurology, Washington University School of Medicine, St Louis, Missouri.

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http://doi.wiley.com/10.1111/jgs.15829
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http://dx.doi.org/10.1111/jgs.15829DOI Listing
April 2019

Reply to: Major Clinical Trials Failed the Amyloid Hypothesis of Alzheimer's Disease.

Authors:
Eric McDade

J Am Geriatr Soc 2019 Apr 9;67(4):848-849. Epub 2019 Mar 9.

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1111/jgs.15826DOI Listing
April 2019

The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

Mol Psychiatry 2019 Mar 21. Epub 2019 Mar 21.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.

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http://dx.doi.org/10.1038/s41380-019-0404-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754794PMC
March 2019

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease.

Alzheimers Dement 2018 11 25;14(11):1427-1437. Epub 2018 Sep 25.

Section for Dementia Research, Department of Cellular Neurology, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.jalz.2018.06.3059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322213PMC
November 2018

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease.

Neurology 2018 10 14;91(14):e1295-e1306. Epub 2018 Sep 14.

From the Department of Neurology (E.M., J.H., V.B., A.M.F., D.M.H., J.C.M., K.P., R.J.B.), Division of Biostatistics (G.W., C.X.), Department of Radiology (B.A.G., T.L.S.B., D.S.M.), and Department of Pathology (N.J.C.), Washington University School of Medicine, Saint Louis, MO; Department of Neuroscience (A.M.J.), Icahn School of Medicine at Mount Sinai, New York, NY; Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI) (R.A.), Instituto de Investigaciones Neurológicas Raúl Correa, Buenos Aires, Argentina; University of Pittsburgh School of Medicine (S.B.B., W.K.), PA; College of Physicians and Surgeons (J.N.), Columbia University, New York, NY; Department of Neurology (J.R.), Keck School of Medicine of University of Southern California, Los Angeles; Department of Neurology (B.G., M.F.), Indiana University, Indianapolis; Massachusetts General Hospital (R.A.S., J.C.), Harvard Medical School, Boston; Butler Hospital and Brown University (S.S.), Providence, RI; Department of Neurology (N.R.G.-R.), Mayo Clinic Jacksonville, FL; Neuroscience Research Australia (P.R.S.); School of Medical Sciences (P.R.S.), University of New South Wales, Sydney; The Florey Institute and the University of Melbourne (C.M.), Parkville, Australia; Dementia Research Centre, Institute of Neurology (M.N.R., N.C.F.), University College London, UK; German Center for Neurodegenerative Diseases (DZNE) Munich (J.L.); Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) Tübingen (M.J.); and Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177272PMC
October 2018

Tau Positron Emission Tomography in Autosomal Dominant Alzheimer Disease: Small Windows, Big Picture.

JAMA Neurol 2018 05;75(5):536-538

Dominantly Inherited Alzheimer Network Trials Unit, Department of Neurology, Washington University School of Medicine, St Louis, Missouri.

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http://dx.doi.org/10.1001/jamaneurol.2017.4026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970084PMC
May 2018

Amyloid positron emission tomography candidates may focus more on benefits than risks of results disclosure.

Alzheimers Dement (Amst) 2018 30;10:413-420. Epub 2018 May 30.

Alzheimer Disease Research Center, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.dadm.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072672PMC
May 2018

Temporal Cognitive Decline Associated With Exposure to Infectious Agents in a Population-based, Aging Cohort.

Alzheimer Dis Assoc Disord 2016 Jul-Sep;30(3):216-22

Departments of *Psychiatry ∥Medicine ¶Neurology, University of Pittsburgh School of Medicine Departments of †Human Genetics §Biostatistics #Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA ‡Department of Pediatrics, Stanley Division of Neurovirology, Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1097/WAD.0000000000000133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919236PMC
November 2017

Antipsychotics Use in Parkinson Disease: Separating Appropriate Therapies from Treating Inappropriately.

Am J Geriatr Psychiatry 2017 07 14;25(7):706-707. Epub 2017 Mar 14.

Department of Neurology, Washington University in Saint Louis, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2017.03.001DOI Listing
July 2017

Stop Alzheimer's before it starts.

Nature 2017 07;547(7662):153-155

Washington University School of Medicine in St. Louis.

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http://dx.doi.org/10.1038/547153aDOI Listing
July 2017

Rapidly-progressive catatonia responsive to zolpidem in a patient with ovarian teratoma-associated paraneoplastic encephalitis.

J Clin Neurosci 2016 Aug 7;30:136-138. Epub 2016 Mar 7.

Department of Neurology, University of Washington in Saint Louis, 600 South Euclid, Box 8111, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2016.01.028DOI Listing
August 2016

The association between pulse pressure change and cognition in late life: Age and where you start matters.

Alzheimers Dement (Amst) 2016 11;4:56-66. Epub 2016 Jun 11.

Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.dadm.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961825PMC
August 2016

The Dynamic Gait Index in Evaluating Patients with Normal Pressure Hydrocephalus for Cerebrospinal Fluid Diversion.

World Neurosurg 2015 Dec 29;84(6):1871-6. Epub 2015 Aug 29.

Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.wneu.2015.08.021DOI Listing
December 2015

Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease.

Neurology 2015 Sep 5;85(9):790-8. Epub 2015 Aug 5.

From the Departments of Neurology (F.W., D.C.R., S.M., A.M.F., N.J.C., J.C.M., R.J.B.), Radiology (B.A.G., D.S.M., T.L.S.B.), Biostatistics (C.X.), Psychology (J.H.), Neurological Surgery (T.L.S.B.), and Psychiatry (A.G.), Washington University School of Medicine, Saint Louis, MO; Department of Neurology (E.M.), University of Pittsburgh, PA; Mary S. Easton Center for Alzheimer's Disease Research at UCLA (J.M.R.), Los Angeles, CA; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Department of Pathology and Laboratory Medicine (B.G.) and Department of Neurology (M.R.F.), Indiana University School of Medicine, Indianapolis; Center for Alzheimer Research and Treatment (R.S.), Brigham and Women's Hospital and Massachusetts General Hospital, Boston, MA; Department of Neurology (S.S.), Butler Hospital and Warren Alpert Medical School, Brown University, Providence, RI; Neuroscience Research Australia (P.R.S.) and University of New South Wales, Sydney, Australia; Mental Health Research Institute (C.L.M.), University of Melbourne, Parkville, Australia; Centre of Excellence for Alzheimer's Disease Research and Care (R.N.M.), School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Perth, Australia; Dementia Research Centre (M.N.R., C.A.S.L.), UCL Institute of Neurology, London, UK; German Center for Neurodegenerative Diseases (M.J.) and Hertie Institute for Clinical Brain Research, Tübingen, Germany; Neurologische Klinik Ludwig-Maximilians-Universität Munich (A.D.) and German Center for Neurodegenerative Diseases (S.F.), Klinik und Poliklinik für Nuklearmedizin & TUM-Neuroimaging Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; and Department of Neurology (F.W.), Xuan Wu Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1212/WNL.0000000000001903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553024PMC
September 2015

Cerebral bleed after shunt for normal pressure hydrocephalus with cerebral amyloid angiopathy: Coincidence or consequence?

Neurol Clin Pract 2015 Jun;5(3):263-266

Department of Neurology (EM, OL), School of Medicine, University of Pittsburgh, PA; Department of Neurology (BPB), Brigham and Women's Hospital, Boston, MA; and Department of Neurology (MR), Clínica Universidad de Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1212/CPJ.0000000000000127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469348PMC
June 2015

How well do MCI criteria predict progression to severe cognitive impairment and dementia?

Alzheimer Dis Assoc Disord 2014 Apr-Jun;28(2):113-21

Departments of *Psychiatry †Neurology §Medicine, University of Pittsburgh School of Medicine Departments of ‡Epidemiology ∥Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA.

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http://dx.doi.org/10.1097/WAD.0000000000000018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040213PMC
January 2015

Rates and risk factors for progression to incident dementia vary by age in a population cohort.

Neurology 2015 Jan 3;84(1):72-80. Epub 2014 Dec 3.

From the Departments of Psychiatry (M.G., C.-W.L., T.F.H.), Neurology (M.G., B.E.S., E.M.), and Medicine (C.-C.H.C.), School of Medicine, and Departments of Epidemiology (M.G.) and Biostatistics (C.-C.H.C.), Graduate School of Public Health, University of Pittsburgh, PA.

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http://dx.doi.org/10.1212/WNL.0000000000001113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336092PMC
January 2015

Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old.

Neurology 2014 Nov 10;83(20):1804-11. Epub 2014 Oct 10.

From the Departments of Neurology (O.L.L., J.T.B., B.S., M.I., E.M.), Psychiatry (O.L.L., W.E.K., J.T.B., H.J.A.), Radiology (C.M., R.L.C., J.P., A.C.), Pharmaceutical Sciences (C.M.), Psychology (J.T.B.), Biostatistics (L.W.), and Epidemiology, Graduate School of Public Health (L.H.K.), University of Pittsburgh, School of Medicine, PA; and Department of Neurology (S.T.D.), University of Virginia School of Medicine, Charlottesville.

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http://dx.doi.org/10.1212/WNL.0000000000000977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240431PMC
November 2014

Cerebral perfusion alterations and cerebral amyloid in autosomal dominant Alzheimer disease.

Neurology 2014 Aug 16;83(8):710-7. Epub 2014 Jul 16.

From the Departments of Neurology (E.M., S.I., O.L., B.S.), Psychiatry (A.K., J.B., W.K.), and Radiology (J.J., D.M., J.P., C.M., W.K.), School of Medicine, and Department of Psychology (L.K.S., D.C.-H.K., P.J.G.), School of Arts and Sciences, University of Pittsburgh, PA; and Medical College of Georgia (A.K.), Augusta.

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http://dx.doi.org/10.1212/WNL.0000000000000721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150128PMC
August 2014

Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis.

Neurology 2014 Jul 13;83(3):253-60. Epub 2014 Jun 13.

From the Departments of Neurology (D.C.R., J.C.M., R.J.B.), Biostatistics (C.X.), and Psychiatry (A.G.), Washington University School of Medicine, St. Louis, MO; Neurologische Klinik Ludwig-Maximilians-Universität Munich and German Center for Neurodegenerative Diseases (A.D.), Munich, Germany; Department of Neurosciences (P.S.A.), University of California San Diego; Mental Health Research Institute (C.L.M.), University of Melbourne, Australia; Grupo de Neurociencias de Antioquia (N.A.-B., F.L., S.M.), Universidad de Antioquia, Medellín, Colombia; Department of Neurology (E.M.), University of Pittsburgh, PA; Department of Neurology (T.B.), University of Washington, Seattle; Banner Alzheimer's Institute (J.B.S.L., E.M.R., P.N.T.), Phoenix, AZ; Neuroscience Research Australia and University of New South Wales (P.R.S.), Sydney, Australia; Edith Cowan University (R.M.), Western Australia; Easton Center for Alzheimer's Disease Research at UCLA (J.M.R.), Los Angeles, CA; Department of Neurology (R.P.M.), Columbia University, New York, NY; Queen Square Institute of Neurology (N.C.F.), University College London; Department of Neurology (S.S.), Warren Alpert Medical School, Brown University, Providence, RI; and Center for Alzheimer Research and Treatment (R.S.), Brigham and Women's Hospital and Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000000596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117367PMC
July 2014

Treatment of dementia with lewy bodies.

Curr Treat Options Neurol 2013 Dec;15(6):738-64

Department of Neurology, Brigham and Women's Hospital, 221 Longwood Ave, Boston, MA, 02115, USA,

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http://dx.doi.org/10.1007/s11940-013-0261-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913181PMC
December 2013

Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults.

Neurology 2013 Nov 16;81(19):1711-8. Epub 2013 Oct 16.

From the Department of Epidemiology, Graduate School of Public Health (T.M.H., L.H.K., E.J.M.B.-M., R.H.M.), and the Departments of Neurology (E.M.M., B.E.S., O.L.L.), Psychiatry (W.E.K., H.J.A., A.D.C.), and Radiology (C.A.M.), School of Medicine, University of Pittsburgh, PA; and the Office of the Dean and Department of Neurology (S.T.D.), School of Medicine, University of Virginia, Charlottesville.

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http://dx.doi.org/10.1212/01.wnl.0000435301.64776.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812104PMC
November 2013

Incidence of mild cognitive impairment in the Pittsburgh Cardiovascular Health Study-Cognition Study.

Neurology 2012 Oct 26;79(15):1599-606. Epub 2012 Sep 26.

Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1212/WNL.0b013e31826e25f0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475628PMC
October 2012

Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network.

Clin Investig (Lond) 2012 Oct;2(10):975-984

Departments of Neurology and of Pathology and Immunology, and the Programs in Physical Therapy and Occupational Therapy, Washington University, St. Louis, MO (JCM). Other authors' affiliations are as follows: the Departments of Neurology (RB, AF, DH, VB, AO, KM, NS), Biostatistics (CX), Psychiatry (AG), Radiology (TB, DM), and Pathology and Immunology (NC), Washington University School of Medicine, St. Louis; University College London Institute of Neurology, London (MR); the Department of Neurosciences, University of California, San Diego, La Jolla (PA); the Department of Pathology and Laboratory Medicine (BG) and the Center for Bioethics (KQ), Indiana University School of Medicine, Indianapolis; the Departments of Psychiatry (WK) and Neurology (WK, EM), University of Pittsburgh School of Medicine, Pittsburgh; the Centre of Excellence for Alzheimer's Disease Research and Care, Edith Cowan University, Joondalup, WA (RM), the Mental Health Research Institute, University of Melbourne, Melbourne, VIC (CM), and Neuroscience Research Australia and the School of Medical Sciences, University of New South Wales, Sydney (PS) - all in Australia; the Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Department of Neurology, Columbia University College of Physicians and Surgeons, New York (RM); the Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles (JR); the Center for Alzheimer Research and Treatment and the Department of Neurology, Brigham and Women's Hospital, Massachusetts General Hospital, and Harvard Medical School (RS) - all in Boston; the Department of Neurology and the Memory and Aging Program, Butler Hospital, Warren Alpert Medical School of Brown University, Providence, RI (SS); and the Departments of Medicine, Radiology, and Psychiatry, University of California San Francisco (MW).

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http://dx.doi.org/10.4155/cli.12.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489185PMC
October 2012

Evolution of the diagnostic criteria for degenerative and cognitive disorders.

Curr Opin Neurol 2011 Dec;24(6):532-41

Department of Neurology, Alzheimer's Disease Research Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1097/WCO.0b013e32834cd45bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268228PMC
December 2011

Normative spatiotemporal gait parameters in older adults.

Gait Posture 2011 May 29;34(1):111-8. Epub 2011 Apr 29.

Department of Physical Medicine & Rehabilitation, Program in Physical Therapy, College of Medicine, Mayo Clinic, Rochester, MN, United States.

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http://dx.doi.org/10.1016/j.gaitpost.2011.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104090PMC
May 2011

Metatarsal fracture as a consequence of foot dystonia in Parkinson's disease.

Parkinsonism Relat Disord 2008 23;14(4):353-5. Epub 2008 May 23.

Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2007.07.005DOI Listing
October 2008