Eric Kleerup

Eric Kleerup

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Eric Kleerup

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Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users.

Chest 2019 Oct 22;156(4):764-773. Epub 2019 Jun 22.

Bioinformatics Program, Boston University, Boston, MA; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1016/j.chest.2019.05.022DOI Listing
October 2019

Genome-wide association study of lung function and clinical implication in heavy smokers.

BMC Med Genet 2018 08 1;19(1):134. Epub 2018 Aug 1.

Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, BioScience Research Lab, Room 253, 1230 N. Cherry Avenue, PO Box 210242, Tucson, AZ, 85721, USA.

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http://dx.doi.org/10.1186/s12881-018-0656-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090900PMC
August 2018

Fungi stabilize connectivity in the lung and skin microbial ecosystems.

Microbiome 2018 01 15;6(1):12. Epub 2018 Jan 15.

Center for Genomics and Systems Biology, New York University, New York, 10003, NY, USA.

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http://dx.doi.org/10.1186/s40168-017-0393-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769346PMC
January 2018

Use of rosuvastatin in HIV-associated chronic obstructive pulmonary disease.

AIDS 2017 02;31(4):539-544

aDepartment of Medicine bEpidemiology Data Coordinating Center, University of Pittsburgh School of Medicine cGraduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania dDepartment of Medicine, University of California San Francisco, San Francisco, California eDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania fDepartment of Medicine, University of California Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263188PMC
February 2017

Molecular Impact of Electronic Cigarette Aerosol Exposure in Human Bronchial Epithelium.

Toxicol Sci 2017 01 3;155(1):248-257. Epub 2016 Oct 3.

Section of Computational Biomedicine, Department of Medicine Boston University School of Medicine, Boston, Massachusetts 02118.

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http://dx.doi.org/10.1093/toxsci/kfw198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216655PMC
January 2017

Evaluating small-airways disease in asthmatic patients: The utility of quantitative computed tomography.

J Allergy Clin Immunol 2017 01 21;139(1):49-51.e2. Epub 2016 Nov 21.

Department of Radiologic Sciences, David Geffen School of Medicine at UCLA, Los Angeles, Calif.

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http://dx.doi.org/10.1016/j.jaci.2016.11.010DOI Listing
January 2017

Transitions to different patterns of interstitial lung disease in scleroderma with and without treatment.

Ann Rheum Dis 2016 Jul 12;75(7):1367-71. Epub 2016 Jan 12.

Department of Radiological Science, Center for Computer Vision Imaging Biomarker, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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http://dx.doi.org/10.1136/annrheumdis-2015-208929DOI Listing
July 2016

Novel relationships of markers of monocyte activation and endothelial dysfunction with pulmonary dysfunction in HIV-infected persons.

AIDS 2016 06;30(9):1327-39

aDepartment of Medicine, University of Pittsburgh, Pittsburgh bDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California cDepartment of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh dDepartment of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948184PMC
June 2016

Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function.

N Engl J Med 2016 May;374(19):1811-21

From the Cardiovascular Research Institute (P.G.W., S.C.L.) and the Department of Medicine, Division of Pulmonary, Critical Care, Sleep, and Allergy (P.G.W., S.A.C., S.C.L.), University of California at San Francisco, San Francisco; the Departments of Medicine and Epidemiology, Columbia University Medical Center (R.G.B.), and the Department of Medicine, Weill-Cornell Medical College (F.J.M.) - both in New York; the Department of Medicine, Center for Genomics and Personalized Medicine Research, Wake Forest University, Winston-Salem (E.B.), and the Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill (D.C., N.A.G.) - both in North Carolina; the Section of Pulmonary and Critical Care Medicine, Medical Service, Veterans Affairs Ann Arbor Healthcare System (J.L.C.), and the Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan (J.L.C., M.K.H.) - both in Ann Arbor; the Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore (N.N.H.); the Department of Radiology, University of Iowa Carver College of Medicine, Iowa City (E.A.H.); the Department of Medicine, University of Utah Hospitals and Clinics, Salt Lake City (R.E.K., R.P.); the Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles (E.K., D.P.T.); the Department of Medicine, University of Nebraska Medical Center, Omaha (S.R.); and the Clinical Discovery Unit, AstraZeneca, Cambridge, United Kingdom (S.R.).

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http://dx.doi.org/10.1056/NEJMoa1505971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968204PMC
May 2016

Factors associated with abnormal spirometry among HIV-infected individuals.

AIDS 2015 Aug;29(13):1691-700

aDepartment of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland bDepartment of Medicine, School of Medicine, University of California San Francisco, San Francisco, California cDepartment of Medicine, Ohio State University, Columbus, Ohio dDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland eDepartment of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California fDepartments of Medicine and Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania gDivision of Pulmonary & Critical Care Medicine, Departments of Medicine and Environmental Medicine, New York University School of Medicine, New York hClinical Trials and Survey Corporation, Owings Mills, Maryland iDepartment of Medicine, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571285PMC
August 2015

Medicare Payment Policy Creates Incentives For Long-Term Care Hospitals To Time Discharges For Maximum Reimbursement.

Health Aff (Millwood) 2015 Jun;34(6):907-15

Jack Needleman is the Fred W. and Pamela K. Wasserman Professor and Chair of the Department of Health Policy and Management, Fielding School of Public Health, UCLA.

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http://dx.doi.org/10.1377/hlthaff.2014.0778DOI Listing
June 2015

Differences between attendings' and fellows' perceptions of futile treatment in the intensive care unit at one academic health center: implications for training.

Acad Med 2015 Mar;90(3):324-30

Dr. Neville is assistant professor, Department of Medicine, Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Mr. Wiley is a doctoral student in health and quantitative psychology, University of California, Los Angeles, Los Angeles, California. Dr. Holmboe is senior vice president, Milestones Development and Evaluation, Accreditation Council for Graduate Medical Education, and professor adjunct of medicine, Yale University School of Medicine, New Haven, Connecticut. Dr. Tseng is associate professor, Department of Medicine, Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Dr. Vespa is professor of neurology and neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Dr. Kleerup is clinical professor, Department of Medicine, Division of Pulmonary and Critical Care, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Dr. Wenger is professor, Department of Medicine, Division of General Internal Medicine and Health Services Research, and director, Health System Ethics Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, and a scientist at RAND Health, Santa Monica, California.

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http://dx.doi.org/10.1097/ACM.0000000000000617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339400PMC
March 2015

The opportunity cost of futile treatment in the ICU*.

Crit Care Med 2014 Sep;42(9):1977-82

1Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA. 2Emergency Room, Ronald Reagan-UCLA Medical Center, Los Angeles, CA. 3UCLA Health Ethics Center, Los Angeles, CA. 4Division of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA. 5RAND Health, Santa Monica, CA.

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http://www.medical-horizons.net/uploads/files/3.pdf
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CCM.0000000000000402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134705PMC
September 2014

Annual rates of change in pre- vs. post-bronchodilator FEV1 and FVC over 4 years in moderate to very severe COPD.

Respir Med 2013 Dec 22;107(12):1904-11. Epub 2013 Aug 22.

David Geffen School of Medicine at UCLA, 10833 Le Conte Ave., Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2013.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284059PMC
December 2013

HIV infection is associated with diffusing capacity impairment in women.

J Acquir Immune Defic Syndr 2013 Nov;64(3):284-8

*Department of Medicine, University of Pittsburgh, Pittsburgh, PA; †Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA; ‡Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, CA; Departments of §Medicine; ‖Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, CA; and ¶Department of Immunology, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/QAI.0b013e3182a9213aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857225PMC
November 2013

HIV infection is associated with reduced pulmonary diffusing capacity.

J Acquir Immune Defic Syndr 2013 Nov;64(3):271-8

*Department of Medicine, University of Washington, Seattle, WA; †Department of Medicine, University of Pittsburgh, Pittsburgh, PA; ‡Department of Medicine, University of California, Los Angeles, Los Angeles, CA; §Department of Medicine, Atlanta Veterans Affairs Medical Center (VAMC) and Emory University, Atlanta, GA; ‖Department of Medicine, West Los Angeles VAMC and David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, CA; ¶Department of Medicine, James J. Peters Bronx VAMC, Bronx, NY; #Department of Medicine, Michael E. DeBakey Houston VAMC and Baylor College of Medicine, Houston, TX; **Department of Medicine, University of California, San Francisco, San Francisco, CA; ††Department of Medicine, Clinical Trials and Survey Corporation, Owings Mills, MD; ‡‡Department of Medicine, Ohio State University Medical Center, Columbus, OH; §§Department of Medicine, Johns Hopkins University, Baltimore, MD; ‖‖Department of Medicine, New York University School of Medicine, New York, NY; ¶¶Departments of Infectious Diseases and Microbiology; and Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA; and ##Departments of Medicine and Immunology, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/QAI.0b013e3182a9215aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845879PMC
November 2013

The frequency and cost of treatment perceived to be futile in critical care.

JAMA Intern Med 2013 Nov;173(20):1887-94

Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles.

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http://dx.doi.org/10.1001/jamainternmed.2013.10261DOI Listing
November 2013

Factors associated with palliative withdrawal of mechanical ventilation and time to death after withdrawal.

J Palliat Med 2013 Nov 1;16(11):1368-74. Epub 2013 Oct 1.

1 Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California , Los Angeles.

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http://dx.doi.org/10.1089/jpm.2013.0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822388PMC
November 2013

Prognostic factors and outcomes of patients with pulmonary hypertension admitted to the intensive care unit.

J Crit Care 2012 Dec 22;27(6):739.e7-13. Epub 2012 Oct 22.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, UCLA, BOX 951690, 37-131 CHS, Los Angeles, CA 90095-1690, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S08839441120025
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http://dx.doi.org/10.1016/j.jcrc.2012.08.006DOI Listing
December 2012

HIF-1 expression is associated with CCL2 chemokine expression in airway inflammatory cells: implications in allergic airway inflammation.

Respir Res 2012 Jul 23;13:60. Epub 2012 Jul 23.

Hospital Infantil de Mexico, Federico Gomez, Unidad de Investigacion en Enfermedades Oncologicas, Dr, Marquez No 262, Col, Doctores, Delegacion Cuahutemos, Mexico City CP 06720, Mexico.

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http://dx.doi.org/10.1186/1465-9921-13-60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439306PMC
July 2012

Quantitative texture-based assessment of one-year changes in fibrotic reticular patterns on HRCT in scleroderma lung disease treated with oral cyclophosphamide.

Eur Radiol 2011 Dec 17;21(12):2455-65. Epub 2011 Sep 17.

Center for Computer Vision and Imaging Biomarker, Department of Radiological Sciences, David Geffen School of Medicine, UCLA, 924 Westwood Blvd., Suite 650, Los Angeles, CA 90024-2926, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs00330-011-22
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http://link.springer.com/10.1007/s00330-011-2223-2
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http://dx.doi.org/10.1007/s00330-011-2223-2DOI Listing
December 2011

HIV and chronic obstructive pulmonary disease: is it worse and why?

Proc Am Thorac Soc 2011 Jun;8(3):320-5

Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1513/pats.201006-045WRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132792PMC
June 2011

Reproducibility of lung and lobar volume measurements using computed tomography.

Acad Radiol 2010 Mar 8;17(3):316-22. Epub 2009 Dec 8.

Thoracic Imaging Research Group, Los Angeles, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1016/j.acra.2009.10.005DOI Listing
March 2010

Time course and degree of hyperinflation with metronome-paced tachypnea in COPD patients.

COPD 2008 Oct;5(5):298-304

Exercise Physiology Research Laboratory, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1690, USA.

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http://dx.doi.org/10.1080/15412550802363428DOI Listing
October 2008

Quality indicators for the care of chronic obstructive pulmonary disease in vulnerable elders.

Authors:
Eric Kleerup

J Am Geriatr Soc 2007 Oct;55 Suppl 2:S270-6

Division of Pulmonary, Critical Care Medicine and Hospitalists, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2007.01332.xDOI Listing
October 2007

Small airways response to naturalistic cat allergen exposure in subjects with asthma.

J Allergy Clin Immunol 2006 Nov 8;118(5):1075-81. Epub 2006 Sep 8.

Division of Pulmonary, David Geffen School of Medicine and Allergy Research Foundation, University of California, Los Angeles, CA 90025, USA.

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http://search.proquest.com/openview/f9ef465230eadcb60271fa56
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http://linkinghub.elsevier.com/retrieve/pii/S009167490601577
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http://dx.doi.org/10.1016/j.jaci.2006.06.042DOI Listing
November 2006

Exhaled nitric oxide in the assessment of asthma.

Curr Opin Pulm Med 2004 Jan;10(1):31-6

David Geffen School of Medicine at University of California, Los Angeles, USA.

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January 2004

Chronic and acute effects of "crack" cocaine on diffusing capacity, membrane diffusion, and pulmonary capillary blood volume in the lung.

Chest 2002 Aug;122(2):629-38

Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095-1690, USA.

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http://dx.doi.org/10.1378/chest.122.2.629DOI Listing
August 2002

Evidence of chronic damage to the pulmonary microcirculation in habitual users of alkaloidal ("crack") cocaine.

Chest 2002 Apr;121(4):1231-8

Division of Hematology, UCLA School of Medicine, Los Angeles, CA 90095-1678, USA.

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http://dx.doi.org/10.1378/chest.121.4.1231DOI Listing
April 2002

Asthma type A...Z.

Authors:
Eric C Kleerup

Curr Opin Pulm Med 2002 Jan;8(1):1-3

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January 2002