Publications by authors named "Eric Jorgenson"

83Publications

The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Authors:
Dragana Vuckovic Erik L Bao Parsa Akbari Caleb A Lareau Abdou Mousas Tao Jiang Ming-Huei Chen Laura M Raffield Manuel Tardaguila Jennifer E Huffman Scott C Ritchie Karyn Megy Hannes Ponstingl Christopher J Penkett Patrick K Albers Emilie M Wigdor Saori Sakaue Arden Moscati Regina Manansala Ken Sin Lo Huijun Qian Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamy N Chitrala Peter W F Wilson Hélène Choquet John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans Stephan B Felix James S Floyd Linda Broer Niels Grarup Michael H Guo Qi Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotios Koskeridis Leslie A Lange Terho Lehtimäki Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Kjell Nikus Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Stefan Weiss Na Cai Kousik Kundu Stephen B Watt Klaudia Walter Alan B Zonderman Kelly Cho Yun Li Ruth J F Loos Julian C Knight Michel Georges Oliver Stegle Evangelos Evangelou Yukinori Okada David J Roberts Michael Inouye Andrew D Johnson Paul L Auer William J Astle Alexander P Reiner Adam S Butterworth Willem H Ouwehand Guillaume Lettre Vijay G Sankaran Nicole Soranzo

Cell 2020 Sep;182(5):1214-1231.e11

Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.08.008DOI Listing
September 2020

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Authors:
Ming-Huei Chen Laura M Raffield Abdou Mousas Saori Sakaue Jennifer E Huffman Arden Moscati Bhavi Trivedi Tao Jiang Parsa Akbari Dragana Vuckovic Erik L Bao Xue Zhong Regina Manansala Véronique Laplante Minhui Chen Ken Sin Lo Huijun Qian Caleb A Lareau Mélissa Beaudoin Karen A Hunt Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamynaidu Chitrala Kelly Cho Hélène Choquet Adolfo Correa John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans James S Floyd Linda Broer Niels Grarup Michael H Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Qin Qin Huang Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotis Koskeridis Leslie A Lange Terho Lehtimäki Markus M Lerch Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Hilary C Martin Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Matthias Nauck Kjell Nikus Willem H Ouwehand Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari David J Roberts Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Richard C Trembath Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Alan B Zonderman Peter W F Wilson Yun Li Adam S Butterworth Jean-François Gauchat Charleston W K Chiang Bingshan Li Ruth J F Loos William J Astle Evangelos Evangelou David A van Heel Vijay G Sankaran Yukinori Okada Nicole Soranzo Andrew D Johnson Alexander P Reiner Paul L Auer Guillaume Lettre

Cell 2020 Sep;182(5):1198-1213.e14

Montreal Heart Institute, Montreal, QC H1T 1C8, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480402PMC
September 2020

Association of genetic risk for Alzheimer disease and hearing impairment.

Neurology 2020 Sep 2. Epub 2020 Sep 2.

Department of Epidemiology & Biostatistics, University of California, San Francisco, CA.

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http://dx.doi.org/10.1212/WNL.0000000000010709DOI Listing
September 2020

Genetic and environmental factors underlying keratinocyte carcinoma risk.

JCI Insight 2020 May 21;5(10). Epub 2020 May 21.

Kaiser Permanente Northern California, Division of Research, Oakland, California, USA.

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http://dx.doi.org/10.1172/jci.insight.134783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259534PMC
May 2020

Functional validity, role, and implications of heavy alcohol consumption genetic loci.

Sci Adv 2020 01 15;6(3):eaay5034. Epub 2020 Jan 15.

Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1126/sciadv.aay5034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962045PMC
January 2020

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.

PLoS Genet 2019 12 23;15(12):e1008500. Epub 2019 Dec 23.

Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953885PMC
December 2019

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.

Authors:
Michael A Hauser R Rand Allingham Tin Aung Carly J Van Der Heide Kent D Taylor Jerome I Rotter Shih-Hsiu J Wang Pieter W M Bonnemaijer Susan E Williams Sadiq M Abdullahi Khaled K Abu-Amero Michael G Anderson Stephen Akafo Mahmoud B Alhassan Ifeoma Asimadu Radha Ayyagari Saydou Bakayoko Prisca Biangoup Nyamsi Donald W Bowden William C Bromley Donald L Budenz Trevor R Carmichael Pratap Challa Yii-Der Ida Chen Chimdi M Chuka-Okosa Jessica N Cooke Bailey Vital Paulino Costa Dianne A Cruz Harvey DuBiner John F Ervin Robert M Feldman Miles Flamme-Wiese Douglas E Gaasterland Sarah J Garnai Christopher A Girkin Nouhoum Guirou Xiuqing Guo Jonathan L Haines Christopher J Hammond Leon Herndon Thomas J Hoffmann Christine M Hulette Abba Hydara Robert P Igo Eric Jorgenson Joyce Kabwe Ngoy Janvier Kilangalanga Nkiru Kizor-Akaraiwe Rachel W Kuchtey Hasnaa Lamari Zheng Li Jeffrey M Liebmann Yutao Liu Ruth J F Loos Monica B Melo Sayoko E Moroi Joseph M Msosa Robert F Mullins Girish Nadkarni Abdoulaye Napo Maggie C Y Ng Hugo Freire Nunes Ebenezer Obeng-Nyarkoh Anthony Okeke Suhanya Okeke Olusegun Olaniyi Olusola Olawoye Mariana Borges Oliveira Louise R Pasquale Rodolfo A Perez-Grossmann Margaret A Pericak-Vance Xue Qin Michele Ramsay Serge Resnikoff Julia E Richards Rui Barroso Schimiti Kar Seng Sim William E Sponsel Paulo Vinicius Svidnicki Alberta A H J Thiadens Nkechinyere J Uche Cornelia M van Duijn José Paulo Cabral de Vasconcellos Janey L Wiggs Linda M Zangwill Neil Risch Dan Milea Adeyinka Ashaye Caroline C W Klaver Robert N Weinreb Allison E Ashley Koch John H Fingert Chiea Chuen Khor

JAMA 2019 11;322(17):1682-1691

Singapore Eye Research Institute, Singapore.

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http://dx.doi.org/10.1001/jama.2019.16161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865235PMC
November 2019

Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol.

Clin Pharmacol Ther 2019 09 23;106(3):623-631. Epub 2019 May 23.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1002/cpt.1439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941886PMC
September 2019

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.

Authors:
Mengzhen Liu Yu Jiang Robbee Wedow Yue Li David M Brazel Fang Chen Gargi Datta Jose Davila-Velderrain Daniel McGuire Chao Tian Xiaowei Zhan Hélène Choquet Anna R Docherty Jessica D Faul Johanna R Foerster Lars G Fritsche Maiken Elvestad Gabrielsen Scott D Gordon Jeffrey Haessler Jouke-Jan Hottenga Hongyan Huang Seon-Kyeong Jang Philip R Jansen Yueh Ling Reedik Mägi Nana Matoba George McMahon Antonella Mulas Valeria Orrù Teemu Palviainen Anita Pandit Gunnar W Reginsson Anne Heidi Skogholt Jennifer A Smith Amy E Taylor Constance Turman Gonneke Willemsen Hannah Young Kendra A Young Gregory J M Zajac Wei Zhao Wei Zhou Gyda Bjornsdottir Jason D Boardman Michael Boehnke Dorret I Boomsma Chu Chen Francesco Cucca Gareth E Davies Charles B Eaton Marissa A Ehringer Tõnu Esko Edoardo Fiorillo Nathan A Gillespie Daniel F Gudbjartsson Toomas Haller Kathleen Mullan Harris Andrew C Heath John K Hewitt Ian B Hickie John E Hokanson Christian J Hopfer David J Hunter William G Iacono Eric O Johnson Yoichiro Kamatani Sharon L R Kardia Matthew C Keller Manolis Kellis Charles Kooperberg Peter Kraft Kenneth S Krauter Markku Laakso Penelope A Lind Anu Loukola Sharon M Lutz Pamela A F Madden Nicholas G Martin Matt McGue Matthew B McQueen Sarah E Medland Andres Metspalu Karen L Mohlke Jonas B Nielsen Yukinori Okada Ulrike Peters Tinca J C Polderman Danielle Posthuma Alexander P Reiner John P Rice Eric Rimm Richard J Rose Valgerdur Runarsdottir Michael C Stallings Alena Stančáková Hreinn Stefansson Khanh K Thai Hilary A Tindle Thorarinn Tyrfingsson Tamara L Wall David R Weir Constance Weisner John B Whitfield Bendik Slagsvold Winsvold Jie Yin Luisa Zuccolo Laura J Bierut Kristian Hveem James J Lee Marcus R Munafò Nancy L Saccone Cristen J Willer Marilyn C Cornelis Sean P David David A Hinds Eric Jorgenson Jaakko Kaprio Jerry A Stitzel Kari Stefansson Thorgeir E Thorgeirsson Gonçalo Abecasis Dajiang J Liu Scott Vrieze

Nat Genet 2019 02 14;51(2):237-244. Epub 2019 Jan 14.

Department of Psychology, University of Minnesota Twin Cities, Minneapolis, MN, USA.

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http://www.nature.com/articles/s41588-018-0307-5
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http://dx.doi.org/10.1038/s41588-018-0307-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358542PMC
February 2019

Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults.

J Allergy Clin Immunol 2019 04 20;143(4):1633-1635. Epub 2018 Dec 20.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Mass. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183277
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http://dx.doi.org/10.1016/j.jaci.2018.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451881PMC
April 2019

A Prediction Tool to Facilitate Risk-Stratified Screening for Squamous Cell Skin Cancer.

J Invest Dermatol 2018 12 2;138(12):2589-2594. Epub 2018 Jul 2.

Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.03.1528DOI Listing
December 2018

Genetic variants in the HLA class II region associated with risk of cutaneous squamous cell carcinoma.

Cancer Immunol Immunother 2018 Jul 12;67(7):1123-1133. Epub 2018 May 12.

Department of Dermatology, Massachusetts General Hospital, 50 Staniford Street, Suite 270, 02114, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00262-018-2168-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081741PMC
July 2018

Common Mitochondrial Haplogroups and Cutaneous Squamous Cell Carcinoma Risk.

Cancer Epidemiol Biomarkers Prev 2018 07 25;27(7):838-841. Epub 2018 Apr 25.

Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241517PMC
July 2018

Reply.

Am J Ophthalmol 2018 05 23;189:176-177. Epub 2018 Mar 23.

Pasadena, California.

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https://linkinghub.elsevier.com/retrieve/pii/S00029394183007
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http://dx.doi.org/10.1016/j.ajo.2018.02.013DOI Listing
May 2018

The Relationship Between Nonsteroidal Anti-inflammatory Drug Use and Age-related Macular Degeneration.

Am J Ophthalmol 2018 04 31;188:111-122. Epub 2018 Jan 31.

Department of Research and Evaluation, Southern California Permanente Medical Group, Pasadena, California.

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https://linkinghub.elsevier.com/retrieve/pii/S00029394183001
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http://dx.doi.org/10.1016/j.ajo.2018.01.012DOI Listing
April 2018

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

J Allergy Clin Immunol 2018 11 9;142(5):1469-1478.e2. Epub 2018 Jan 9.

Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037620PMC
November 2018

Susceptibility Loci-Associated Cutaneous Squamous Cell Carcinoma Invasiveness.

J Invest Dermatol 2018 03 17;138(3):557-561. Epub 2017 Oct 17.

Division of Research, Kaiser Permanente Northern California, Oakland, California, USA; Department of Dermatology, Massachusetts General Hospital, and Department of Population Medicine, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.09.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211552PMC
March 2018

A GWAS of Cutaneous Squamous Cell Carcinoma-Letter.

Cancer Epidemiol Biomarkers Prev 2016 11;25(11):1534

Division of Research, Kaiser Permanente Northern California, Oakland, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113720PMC
November 2016

Clinical Utility of Multimarker Genetic Risk Scores for Prediction of Incident Coronary Heart Disease: A Cohort Study Among Over 51 000 Individuals of European Ancestry.

Circ Cardiovasc Genet 2016 12 25;9(6):531-540. Epub 2016 Oct 25.

From the Kaiser Permanente Northern California Division of Research, Oakland, CA (C.I., M.L., E.J.); Gendiag, Inc/Ferrer inCode, Inc, Barcelona, Spain (M.M., C.L.-G., E.S.); CIBER of Epidemiology and Public Health, Barcelona, Spain (I.S.); and Cardiovascular Epidemiology & Genetics, IMIM, Barcelona, Spain (I.S., R.E.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001522DOI Listing
December 2016

Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma.

J Invest Dermatol 2016 05 29;136(5):930-937. Epub 2016 Jan 29.

Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842155PMC
May 2016

A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia.

Nat Commun 2015 Dec 21;6:10130. Epub 2015 Dec 21.

Kaiser Permanente Northern California, Division of Research, Oakland, California 94612, USA.

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http://dx.doi.org/10.1038/ncomms10130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703831PMC
December 2015

The Association of Refractive Error with Glaucoma in a Multiethnic Population.

Ophthalmology 2016 Jan 8;123(1):92-101. Epub 2015 Aug 8.

Division of Research, Kaiser Permanente Northern California, Oakland, California. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2015.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695304PMC
January 2016

A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.

Cancer Discov 2015 Aug 1;5(8):878-91. Epub 2015 Jun 1.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California. Institute for Human Genetics, University of California, San Francisco, San Francisco, California. Department of Urology, University of California, San Francisco, San Francisco, California. UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527942PMC
August 2015

Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort.

PLoS Genet 2015 Jan 28;11(1):e1004930. Epub 2015 Jan 28.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America; Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America; Department of Urology, University of California San Francisco, San Francisco, California, United States of America.

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http://pstorage-plos-3567654.s3.amazonaws.com/2153202/S2_Fil
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http://dx.plos.org/10.1371/journal.pgen.1004930
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http://dx.doi.org/10.1371/journal.pgen.1004930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309593PMC
January 2015

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Authors:
Michael V Holmes Caroline E Dale Luisa Zuccolo Richard J Silverwood Yiran Guo Zheng Ye David Prieto-Merino Abbas Dehghan Stella Trompet Andrew Wong Alana Cavadino Dagmar Drogan Sandosh Padmanabhan Shanshan Li Ajay Yesupriya Maarten Leusink Johan Sundstrom Jaroslav A Hubacek Hynek Pikhart Daniel I Swerdlow Andrie G Panayiotou Svetlana A Borinskaya Chris Finan Sonia Shah Karoline B Kuchenbaecker Tina Shah Jorgen Engmann Lasse Folkersen Per Eriksson Fulvio Ricceri Olle Melander Carlotta Sacerdote Dale M Gamble Sruti Rayaprolu Owen A Ross Stela McLachlan Olga Vikhireva Ivonne Sluijs Robert A Scott Vera Adamkova Leon Flicker Frank M van Bockxmeer Christine Power Pedro Marques-Vidal Tom Meade Michael G Marmot Jose M Ferro Sofia Paulos-Pinheiro Steve E Humphries Philippa J Talmud Irene Mateo Leach Niek Verweij Allan Linneberg Tea Skaaby Pieter A Doevendans Maarten J Cramer Pim van der Harst Olaf H Klungel Nicole F Dowling Anna F Dominiczak Meena Kumari Andrew N Nicolaides Cornelia Weikert Heiner Boeing Shah Ebrahim Tom R Gaunt Jackie F Price Lars Lannfelt Anne Peasey Ruzena Kubinova Andrzej Pajak Sofia Malyutina Mikhail I Voevoda Abdonas Tamosiunas Anke H Maitland-van der Zee Paul E Norman Graeme J Hankey Manuela M Bergmann Albert Hofman Oscar H Franco Jackie Cooper Jutta Palmen Wilko Spiering Pim A de Jong Diana Kuh Rebecca Hardy Andre G Uitterlinden M Arfan Ikram Ian Ford Elina Hyppönen Osvaldo P Almeida Nicholas J Wareham Kay-Tee Khaw Anders Hamsten Lise Lotte N Husemoen Anne Tjønneland Janne S Tolstrup Eric Rimm Joline W J Beulens W M Monique Verschuren N Charlotte Onland-Moret Marten H Hofker S Goya Wannamethee Peter H Whincup Richard Morris Astrid M Vicente Hugh Watkins Martin Farrall J Wouter Jukema James Meschia L Adrienne Cupples Stephen J Sharp Myriam Fornage Charles Kooperberg Andrea Z LaCroix James Y Dai Matthew B Lanktree David S Siscovick Eric Jorgenson Bonnie Spring Josef Coresh Yun R Li Sarah G Buxbaum Pamela J Schreiner R Curtis Ellison Michael Y Tsai Sanjay R Patel Susan Redline Andrew D Johnson Ron C Hoogeveen Hakon Hakonarson Jerome I Rotter Eric Boerwinkle Paul I W de Bakker Mika Kivimaki Folkert W Asselbergs Naveed Sattar Debbie A Lawlor John Whittaker George Davey Smith Kenneth Mukamal Bruce M Psaty James G Wilson Leslie A Lange Ajna Hamidovic Aroon D Hingorani Børge G Nordestgaard Martin Bobak David A Leon Claudia Langenberg Tom M Palmer Alex P Reiner Brendan J Keating Frank Dudbridge Juan P Casas

BMJ 2014 Jul 10;349:g4164. Epub 2014 Jul 10.

Genetic Epidemiology Group, Institute of Cardiovascular Science, Department of Epidemiology and Public Health, University College London, UK Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091648PMC
http://dx.doi.org/10.1136/bmj.g4164DOI Listing
July 2014

Turning of COGS moves forward findings for hormonally mediated cancers.

Nat Genet 2013 Apr;45(4):345-8

Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.

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http://dx.doi.org/10.1038/ng.2587DOI Listing
April 2013

The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies.

Genet Epidemiol 2013 May 25;37(4):383-92. Epub 2013 Mar 25.

Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158-9001, USA.

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http://dx.doi.org/10.1002/gepi.21724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291231PMC
May 2013

Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study.

Alcohol Clin Exp Res 2013 Aug 4;37(8):1311-6. Epub 2013 Mar 4.

Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research, University of California, San Francisco, San Francisco, CA 94110, USA.

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http://doi.wiley.com/10.1111/acer.12099
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http://dx.doi.org/10.1111/acer.12099DOI Listing
August 2013

Contribution of common PCSK1 genetic variants to obesity in 8,359 subjects from multi-ethnic American population.

PLoS One 2013 25;8(2):e57857. Epub 2013 Feb 25.

Ernest Gallo Clinic and Research Center, Emeryville, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057857PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581482PMC
January 2014

Detection of identity by descent using next-generation whole genome sequencing data.

BMC Bioinformatics 2012 Jun 6;13:121. Epub 2012 Jun 6.

Ernest Gallo Clinic and Research Center, University of California San Francisco, 5858 Horton St., Suite 200, Emeryville, CA 94608, USA.

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http://dx.doi.org/10.1186/1471-2105-13-121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403908PMC
June 2012

Genome-wide association studies and cancer.

Hawaii Med J 2010 Oct;69(10):249-51

Department of Neurology, Ernest Gallo Clinic and Research Center at the University of California, San Francisco, Emeryville, CA 94608, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071183PMC
October 2010

Genome-wide association studies in pharmacogenomics: successes and lessons.

Pharmacogenet Genomics 2013 Aug;23(8):383-94

Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695-7566, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32833d7b45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003940PMC
August 2013

Human genetic variation recognizes functional elements in noncoding sequence.

Genome Res 2010 Mar 23;20(3):311-9. Epub 2009 Dec 23.

Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1101/gr.094151.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840987PMC
March 2010

New tools for functional genomic analysis.

Drug Discov Today 2009 Aug 27;14(15-16):754-60. Epub 2009 May 27.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, United States.

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http://dx.doi.org/10.1016/j.drudis.2009.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720446PMC
August 2009

VALID: visualization of association study results and linkage disequilibrium.

Genet Epidemiol 2009 Nov;33(7):599-603

Department of Biopharmaceutical Sciences, University of California, San Francisco, San Francisco, California 94143-0794, USA.

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http://dx.doi.org/10.1002/gepi.20411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258024PMC
November 2009

An empirical evaluation of the common disease-common variant hypothesis.

BMC Proc 2007 18;1 Suppl 1:S5. Epub 2007 Dec 18.

Department of Epidemiology and Biostatistics, Institute for Human Genetics, Universityof California, San Francisco, California 94143-0794, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367531PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s5DOI Listing
December 2009

8q24 and prostate cancer: association with advanced disease and meta-analysis.

Eur J Hum Genet 2008 Apr 30;16(4):496-505. Epub 2008 Jan 30.

Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143-0794, USA.

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http://dx.doi.org/10.1038/sj.ejhg.5201959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819154PMC
April 2008

Genome-wide association studies of cancer.

Future Oncol 2007 Aug;3(4):419-27

University of California, Department of Epidemiology & Biostatistics , San Francisco, CA 94143-0794, USA.

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https://www.futuremedicine.com/doi/10.2217/14796694.3.4.419
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August 2007

Association of testis derived transcript gene variants and prostate cancer risk.

J Urol 2007 Mar;177(3):894-8

Department of Epidemiology and Biostatistics, and Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94143-0794, USA.

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http://dx.doi.org/10.1016/j.juro.2006.10.057DOI Listing
March 2007

Trans-fatty acid intake and increased risk of advanced prostate cancer: modification by RNASEL R462Q variant.

Carcinogenesis 2007 Jun 18;28(6):1232-6. Epub 2007 Jan 18.

Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, CA 94143-0794, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgm002DOI Listing
June 2007

Genome-wide linkage analysis of lipids in nondiabetic Chinese and Japanese from the SAPPHIRe family study.

Am J Hypertens 2006 Dec;19(12):1270-7

Division of Biostatistics and Bioinformatics, National Health Research Institutes, Miaoli, Taiwan.

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http://dx.doi.org/10.1016/j.amjhyper.2006.05.004DOI Listing
December 2006

A gene-centric approach to genome-wide association studies.

Nat Rev Genet 2006 Nov;7(11):885-91

Department of Epidemiology and Biostatistics, and Center for Human Genetics, University of California, San Francisco, California 94143-0794, USA.

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http://www.nature.com/articles/nrg1962
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November 2006

Plasminogen activator inhibitor type-1 (PAI-1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history.

Prostate 2007 Feb;67(2):172-7

Department of Epidemiology and Biostatistics, Center for Human Genetics, University of California, San Francisco, San Francisco, California 94143-0794, USA.

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http://doi.wiley.com/10.1002/pros.20512
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February 2007

Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans.

Hum Genet 2006 Jul 5;119(6):624-33. Epub 2006 May 5.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1007/s00439-006-0175-4DOI Listing
July 2006

Coverage and power in genomewide association studies.

Am J Hum Genet 2006 May 17;78(5):884-888. Epub 2006 Mar 17.

Department of Epidemiology and Biostatistics and Center for Human Genetics, University of California-San Francisco, San Francisco.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297076382
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http://dx.doi.org/10.1086/503751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474045PMC
May 2006

Hierarchical modeling in association studies of multiple phenotypes.

BMC Genet 2005 Dec 30;6 Suppl 1:S104. Epub 2005 Dec 30.

Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143-0560, USA.

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http://dx.doi.org/10.1186/1471-2156-6-S1-S104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866835PMC
December 2005

Case-control analyses: Geneopardy!

Genet Epidemiol 2005 ;29 Suppl 1:S86-90

Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1002/gepi.20114DOI Listing
April 2006

Ethnicity and human genetic linkage maps.

Am J Hum Genet 2005 Feb 30;76(2):276-90. Epub 2004 Dec 30.

Department of Genetics, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1086/427926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1196373PMC
February 2005

Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide.

Science 2003 Feb;299(5610):1221-5

National Institute on Deafness and Other Communication Disorders, National Institutes of Health, 5 Research Court, Rockville, MD 20850, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1080190
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February 2003