Eric J Vallender

Eric J Vallender

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Eric J Vallender

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Decreased core symptoms of mania and utilization of lithium/mood stabilizing anticonvulsants in U.S. bipolar I patients of African vs European ancestry.

J Affect Disord 2019 Sep 4;260:361-365. Epub 2019 Sep 4.

Department of Psychiatry & Psychology, Mayo Clinic, 200 First ST SW, Rochester, MN, 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.09.022DOI Listing
September 2019

Alcohol-induced changes in the gut microbiome and metabolome of rhesus macaques.

Psychopharmacology (Berl) 2019 May 22;236(5):1531-1544. Epub 2019 Mar 22.

Program in Neuroscience, University of Mississippi Medical Center, Jackson, MS, USA.

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http://dx.doi.org/10.1007/s00213-019-05217-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613802PMC
May 2019

Altered neuro-inflammatory gene expression in hippocampus in major depressive disorder.

Prog Neuropsychopharmacol Biol Psychiatry 2018 03 22;82:177-186. Epub 2017 Nov 22.

Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS, USA; Psychiatry, Case Western Reserve University, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2017.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801125PMC
March 2018

Persistent negative effects of alcohol drinking on aspects of novelty-directed behavior in male rhesus macaques.

Alcohol 2017 Sep 23;63:19-26. Epub 2017 Jun 23.

Graduate Program in Neuroscience, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Psychiatry & Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Neurobiology & Anatomical Sciences, University of Mississippi Medical Center, Jackson, MS 39216, USA; Harvard Medical School/NEPRC, Southborough, MA 01772, USA. Electronic address:

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http://dx.doi.org/10.1016/j.alcohol.2017.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584881PMC
September 2017

Convergent Balancing Selection on the Mu-Opioid Receptor in Primates.

Mol Biol Evol 2017 07;34(7):1629-1643

Division of Neuroscience, New England Primate Research Center, Harvard Medical School, Southborough, MA.

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http://dx.doi.org/10.1093/molbev/msx105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279279PMC
July 2017

Transcriptomic profiling of the ventral tegmental area and nucleus accumbens in rhesus macaques following long-term cocaine self-administration.

Drug Alcohol Depend 2017 06 18;175:9-23. Epub 2017 Mar 18.

Harvard Medical School, New England Primate Research Center, Southborough, MA 01772, United States; University of Mississippi Medical Center, Jackson, MS 39216, United States; Tulane National Primate Research Center, Covington, LA 70433, United States; University of Massachusetts-Amherst, Amherst, MA 01003, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2017.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693237PMC
June 2017

Biogeography of the intestinal mucosal and lumenal microbiome in the rhesus macaque.

Cell Host Microbe 2015 Mar 26;17(3):385-391. Epub 2015 Feb 26.

Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369771PMC
March 2015

Genetic substructure in cynomolgus macaques (Macaca fascicularis) on the island of Mauritius.

BMC Genomics 2014 Aug 31;15:748. Epub 2014 Aug 31.

New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1186/1471-2164-15-748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167525PMC
August 2014

Evolutionary conservation in genes underlying human psychiatric disorders.

Front Hum Neurosci 2014 6;8:283. Epub 2014 May 6.

Division of Neuroscience, New England Primate Research Center, Harvard Medical School Southborough, MA, USA.

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http://dx.doi.org/10.3389/fnhum.2014.00283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018557PMC
May 2014

Twinning and survivorship of captive common marmosets (Callithrix jacchus) and cotton-top tamarins (Saguinus oedipus).

J Am Assoc Lab Anim Sci 2014 Jan;53(1):7-11

New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894641PMC
January 2014

Large-scale polymorphism discovery in macaque G-protein coupled receptors.

BMC Genomics 2013 Oct 11;14:703. Epub 2013 Oct 11.

New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1186/1471-2164-14-703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907043PMC
October 2013

How brains are built: genetics and evolution.

Authors:
Eric J Vallender

Brain Behav Evol 2013 6;81(2):71-3. Epub 2013 Mar 6.

New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1159/000347054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632431PMC
September 2013

Trace amine associated receptor 1 modulates behavioral effects of ethanol.

Subst Abuse 2013 4;7:117-26. Epub 2013 Jun 4.

Division of Neuroscience, New England Primate Research Center, Harvard Medical School, Southborough, MA, USA.

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http://dx.doi.org/10.4137/SART.S12110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682756PMC
July 2013

Naturally occurring, physiologically normal, primate chimeras.

Chimerism 2012 Apr-Jun;3(2):43-4. Epub 2012 Apr 1.

New England Primate Research Center, Harvard Medical School, Southborough, MA, USA.

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http://dx.doi.org/10.4161/chim.20729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442812PMC
January 2013

Trace amine associated receptor 1 signaling in activated lymphocytes.

J Neuroimmune Pharmacol 2012 Dec 29;7(4):866-76. Epub 2011 Oct 29.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s11481-011-9321-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593117PMC
December 2012

The resurgence and genetic implications of New World primates in biomedical research.

Trends Genet 2012 Dec 22;28(12):586-91. Epub 2012 Oct 22.

New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1016/j.tig.2012.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500444PMC
December 2012

Genetic correlates of the evolving primate brain.

Authors:
Eric J Vallender

Prog Brain Res 2012 ;195:27-44

New England Primate Research Center, Harvard Medical School, Southborough, MA, USA.

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http://dx.doi.org/10.1016/B978-0-444-53860-4.00002-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514414PMC
May 2012

Augmentation of methamphetamine-induced behaviors in transgenic mice lacking the trace amine-associated receptor 1.

Pharmacol Biochem Behav 2012 Apr 4;101(2):201-7. Epub 2011 Nov 4.

Division of Neuroscience, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S009130571100354
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http://dx.doi.org/10.1016/j.pbb.2011.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288391PMC
April 2012

Quantitative molecular assessment of chimerism across tissues in marmosets and tamarins.

BMC Genomics 2012 Mar 19;13:98. Epub 2012 Mar 19.

New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1186/1471-2164-13-98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337283PMC
March 2012

Growth-associated protein-43 and ephrin B3 induction in the brain of adult SIV-infected rhesus macaques.

J Neurovirol 2011 Oct 26;17(5):455-68. Epub 2011 Jul 26.

Division of Comparative Pathology, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1007/s13365-011-0047-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777635PMC
October 2011

Expanding whole exome resequencing into non-human primates.

Authors:
Eric J Vallender

Genome Biol 2011 Sep 14;12(9):R87. Epub 2011 Sep 14.

New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2011-12-9-r87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308050PMC
September 2011

Comparative genetic approaches to the evolution of human brain and behavior.

Authors:
Eric J Vallender

Am J Hum Biol 2011 Jan-Feb;23(1):53-64

New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, USA.

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http://dx.doi.org/10.1002/ajhb.21132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264672PMC
March 2011

A pharmacogenetic model of naltrexone-induced attenuation of alcohol consumption in rhesus monkeys.

Drug Alcohol Depend 2010 Jun 13;109(1-3):252-6. Epub 2010 Feb 13.

New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2010.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875311PMC
June 2010

Functional evolution of the trace amine associated receptors in mammals and the loss of TAAR1 in dogs.

BMC Evol Biol 2010 Feb 18;10:51. Epub 2010 Feb 18.

New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1186/1471-2148-10-51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838891PMC
February 2010

Bioinformatic approaches to identifying orthologs and assessing evolutionary relationships.

Authors:
Eric J Vallender

Methods 2009 Sep 23;49(1):50-5. Epub 2009 May 23.

Division of Neurosciences, New England Primate Research Center, Harvard Medical School, Pine Hill Drive, Southborough Campus, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1016/j.ymeth.2009.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732758PMC
September 2009

Polymorphisms in the 3' UTR of the serotonin transporter are associated with cognitive flexibility in rhesus macaques.

Am J Med Genet B Neuropsychiatr Genet 2009 Jun;150B(4):467-75

Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA.

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http://dx.doi.org/10.1002/ajmg.b.30835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702718PMC
June 2009

Exploring the origins of the human brain through molecular evolution.

Authors:
Eric J Vallender

Brain Behav Evol 2008 7;72(2):168-77. Epub 2008 Oct 7.

Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1159/000151476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700753PMC
December 2008

Genetic basis of human brain evolution.

Trends Neurosci 2008 Dec 8;31(12):637-44. Epub 2008 Oct 8.

Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1016/j.tins.2008.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715140PMC
December 2008

Cloning, expression, and functional analysis of rhesus monkey trace amine-associated receptor 6: evidence for lack of monoaminergic association.

J Neurosci Res 2008 Nov;86(15):3435-46

Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA.

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http://dx.doi.org/10.1002/jnr.21783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644554PMC
November 2008

Human expression variation in the mu-opioid receptor is paralleled in rhesus macaque.

Behav Genet 2008 Jul 1;38(4):390-5. Epub 2008 Apr 1.

Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1007/s10519-008-9207-2DOI Listing
July 2008

Functional characterization of the human TPH2 5' regulatory region: untranslated region and polymorphisms modulate gene expression in vitro.

Hum Genet 2008 Jan 31;122(6):645-57. Epub 2007 Oct 31.

New England Primate Research Center, Division of Neurochemistry, Harvard Medical School, One Pine Hill Drive, Southborough, MA, 01772-9102, USA.

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http://dx.doi.org/10.1007/s00439-007-0443-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734478PMC
January 2008

Uncovering the mutation-fixation correlation in short lineages.

BMC Evol Biol 2007 Sep 21;7:168. Epub 2007 Sep 21.

Howard Hughes Medical Institute, Department of Human Genetics, and Committee on Genetics, University of Chicago, USA.

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http://dx.doi.org/10.1186/1471-2148-7-168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071921PMC
September 2007

Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro.

J Pharmacol Exp Ther 2007 Apr 18;321(1):116-27. Epub 2007 Jan 18.

Division of Neurochemistry, New England Primate Research Center, Harvard Medical School, One Pine Hill Dr., Southborough, MA 01772, USA.

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http://dx.doi.org/10.1124/jpet.106.116863DOI Listing
April 2007

Evolutionary and biomedical insights from the rhesus macaque genome.

Authors:
Richard A Gibbs Jeffrey Rogers Michael G Katze Roger Bumgarner George M Weinstock Elaine R Mardis Karin A Remington Robert L Strausberg J Craig Venter Richard K Wilson Mark A Batzer Carlos D Bustamante Evan E Eichler Matthew W Hahn Ross C Hardison Kateryna D Makova Webb Miller Aleksandar Milosavljevic Robert E Palermo Adam Siepel James M Sikela Tony Attaway Stephanie Bell Kelly E Bernard Christian J Buhay Mimi N Chandrabose Marvin Dao Clay Davis Kimberly D Delehaunty Yan Ding Huyen H Dinh Shannon Dugan-Rocha Lucinda A Fulton Ramatu Ayiesha Gabisi Toni T Garner Jennifer Godfrey Alicia C Hawes Judith Hernandez Sandra Hines Michael Holder Jennifer Hume Shalini N Jhangiani Vandita Joshi Ziad Mohid Khan Ewen F Kirkness Andrew Cree R Gerald Fowler Sandra Lee Lora R Lewis Zhangwan Li Yih-Shin Liu Stephanie M Moore Donna Muzny Lynne V Nazareth Dinh Ngoc Ngo Geoffrey O Okwuonu Grace Pai David Parker Heidie A Paul Cynthia Pfannkoch Craig S Pohl Yu-Hui Rogers San Juana Ruiz Aniko Sabo Jireh Santibanez Brian W Schneider Scott M Smith Erica Sodergren Amanda F Svatek Teresa R Utterback Selina Vattathil Wesley Warren Courtney Sherell White Asif T Chinwalla Yucheng Feng Aaron L Halpern Ladeana W Hillier Xiaoqiu Huang Pat Minx Joanne O Nelson Kymberlie H Pepin Xiang Qin Granger G Sutton Eli Venter Brian P Walenz John W Wallis Kim C Worley Shiaw-Pyng Yang Steven M Jones Marco A Marra Mariano Rocchi Jacqueline E Schein Robert Baertsch Laura Clarke Miklós Csürös Jarret Glasscock R Alan Harris Paul Havlak Andrew R Jackson Huaiyang Jiang Yue Liu David N Messina Yufeng Shen Henry Xing-Zhi Song Todd Wylie Lan Zhang Ewan Birney Kyudong Han Miriam K Konkel Jungnam Lee Arian F A Smit Brygg Ullmer Hui Wang Jinchuan Xing Richard Burhans Ze Cheng John E Karro Jian Ma Brian Raney Xinwei She Michael J Cox Jeffery P Demuth Laura J Dumas Sang-Gook Han Janet Hopkins Anis Karimpour-Fard Young H Kim Jonathan R Pollack Tomas Vinar Charles Addo-Quaye Jeremiah Degenhardt Alexandra Denby Melissa J Hubisz Amit Indap Carolin Kosiol Bruce T Lahn Heather A Lawson Alison Marklein Rasmus Nielsen Eric J Vallender Andrew G Clark Betsy Ferguson Ryan D Hernandez Kashif Hirani Hildegard Kehrer-Sawatzki Jessica Kolb Shobha Patil Ling-Ling Pu Yanru Ren David Glenn Smith David A Wheeler Ian Schenck Edward V Ball Rui Chen David N Cooper Belinda Giardine Fan Hsu W James Kent Arthur Lesk David L Nelson William E O'brien Kay Prüfer Peter D Stenson James C Wallace Hui Ke Xiao-Ming Liu Peng Wang Andy Peng Xiang Fan Yang Galt P Barber David Haussler Donna Karolchik Andy D Kern Robert M Kuhn Kayla E Smith Ann S Zwieg

Science 2007 Apr;316(5822):222-34

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1126/science.1139247DOI Listing
April 2007

Systematically assessing the influence of 3-dimensional structural context on the molecular evolution of mammalian proteomes.

Mol Biol Evol 2006 Nov 10;23(11):2131-3. Epub 2006 Aug 10.

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, USA.

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http://dx.doi.org/10.1093/molbev/msl086DOI Listing
November 2006

SPEED: a molecular-evolution-based database of mammalian orthologous groups.

Bioinformatics 2006 Nov 11;22(22):2835-7. Epub 2006 Sep 11.

Department of Human Genetics and Committee on Genetics, Howard Hughes Medical Institute, University of Chicago 920 East 58th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/bioinformatics/btl471DOI Listing
November 2006

Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage.

Proc Natl Acad Sci U S A 2006 Nov 7;103(48):18178-83. Epub 2006 Nov 7.

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.0606966103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635020PMC
November 2006

Multiple independent origins of sex chromosomes in amniotes.

Proc Natl Acad Sci U S A 2006 Nov 20;103(48):18031-2. Epub 2006 Nov 20.

New England Primate Research Center, Division of Neurochemistry, Harvard Medical School, Southborough, MA 01772-9102, USA.

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http://dx.doi.org/10.1073/pnas.0608879103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838700PMC
November 2006

A primate-specific acceleration in the evolution of the caspase-dependent apoptosis pathway.

Hum Mol Genet 2006 Oct 15;15(20):3034-40. Epub 2006 Sep 15.

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1093/hmg/ddl245DOI Listing
October 2006

Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates.

Hum Mol Genet 2006 Jul 10;15(13):2031-7. Epub 2006 May 10.

Department of Human Genetics, Howard Hughes Medical Institute, USA.

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http://dx.doi.org/10.1093/hmg/ddl123DOI Listing
July 2006

Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ.

Gene 2006 Jun 14;375:75-9. Epub 2006 Mar 14.

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.gene.2006.02.019DOI Listing
June 2006

Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans.

Science 2005 Sep;309(5741):1717-20

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1126/science.1113722DOI Listing
September 2005

Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens.

Science 2005 Sep;309(5741):1720-2

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1126/science.1116815DOI Listing
September 2005

A highly unexpected strong correlation between fixation probability of nonsynonymous mutations and mutation rate.

Trends Genet 2005 Jul;21(7):381-5

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.tig.2005.05.005DOI Listing
July 2005

The X chromosome: not just her brother's keeper.

Nat Genet 2005 Apr;37(4):343-5

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http://dx.doi.org/10.1038/ng0405-343DOI Listing
April 2005

Accelerated evolution of nervous system genes in the origin of Homo sapiens.

Cell 2004 Dec;119(7):1027-40

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.cell.2004.11.040DOI Listing
December 2004

Positive selection on the human genome.

Hum Mol Genet 2004 Oct;13 Spec No 2:R245-54

Department of Human Genetics, Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddh253DOI Listing
October 2004

Effects of chromosomal rearrangements on human-chimpanzee molecular evolution.

Genomics 2004 Oct;84(4):757-61

Department of Human Genetics, Howard Hughes Medical Institute, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1016/j.ygeno.2004.07.005DOI Listing
October 2004

Diverse fates of paralogs following segmental duplication of telomeric genes.

Genomics 2004 Aug;84(2):239-47

Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.ygeno.2004.03.001DOI Listing
August 2004

Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size.

Hum Mol Genet 2004 Jun 31;13(11):1139-45. Epub 2004 Mar 31.

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddh126DOI Listing
June 2004

Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans.

Hum Mol Genet 2004 Mar 13;13(5):489-94. Epub 2004 Jan 13.

Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddh055DOI Listing
March 2004

How mammalian sex chromosomes acquired their peculiar gene content.

Bioessays 2004 Feb;26(2):159-69

Howard Hughes Medical Institute and Department of Human Genetics, University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1002/bies.10393DOI Listing
February 2004