Eric J Small

Eric J Small

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Androgen decline and survival during docetaxel therapy in metastatic castration resistant prostate cancer (mCRPC).

Authors:
Charles J Ryan Sandipan Dutta William K Kelly Carly Russell Eric J Small Michael J Morris Mary-Ellen Taplin Susan Halabi

Prostate Cancer Prostatic Dis 2020 Mar 3;23(1):66-73. Epub 2019 May 3.

Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1038/s41391-019-0152-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825875PMC
March 2020

Clinical Outcomes in Cyclin-dependent Kinase 12 Mutant Advanced Prostate Cancer.

Authors:
Melissa A Reimers Steven M Yip Li Zhang Marcin Cieslik Mallika Dhawan Bruce Montgomery Alexander W Wyatt Kim N Chi Eric J Small Arul M Chinnaiyan Ajjai S Alva Felix Y Feng Jonathan Chou

Eur Urol 2020 Mar 20;77(3):333-341. Epub 2019 Oct 20.

Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.eururo.2019.09.036DOI Listing
March 2020

Effect of a Behavioral Intervention to Increase Vegetable Consumption on Cancer Progression Among Men With Early-Stage Prostate Cancer: The MEAL Randomized Clinical Trial.

Authors:
J Kellogg Parsons David Zahrieh James L Mohler Electra Paskett Donna E Hansel Adam S Kibel Heshan Liu Drew K Seisler Loki Natarajan Martha White Olwen Hahn John Taylor Sheri J Hartman Sean P Stroup Peter Van Veldhuizen Lannis Hall Eric J Small Michael J Morris John P Pierce James Marshall

JAMA 2020 01;323(2):140-148

Department of Prevention and Population Sciences, Roswell Park Comprehensive Cancer Center, Buffalo, New York.

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http://dx.doi.org/10.1001/jama.2019.20207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990696PMC
January 2020

MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer.

Authors:
Nicholas G Nickols Ramin Nazarian Shuang G Zhao Victor Tan Vladislav Uzunangelov Zheng Xia Robert Baertsch Elad Neeman Allen C Gao George V Thomas Lauren Howard Amanda M De Hoedt Josh Stuart Theodore Goldstein Kim Chi Martin E Gleave Julie N Graff Tomasz M Beer Justin M Drake Christopher P Evans Rahul Aggarwal Adam Foye Felix Y Feng Eric J Small William J Aronson Stephen J Freedland Owen N Witte Jiaoti Huang Joshi J Alumkal Robert E Reiter Matthew B Rettig

Prostate Cancer Prostatic Dis 2019 12 25;22(4):531-538. Epub 2019 Feb 25.

Department of Urology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1038/s41391-019-0134-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853839PMC
December 2019

The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance.

Authors:
Himisha Beltran Andrew Hruszkewycz Howard I Scher Jeffrey Hildesheim Jennifer Isaacs Evan Y Yu Kathleen Kelly Daniel Lin Adam Dicker Julia Arnold Toby Hecht Max Wicha Rosalie Sears David Rowley Richard White James L Gulley John Lee Maria Diaz Meco Eric J Small Michael Shen Karen Knudsen David W Goodrich Tamara Lotan Amina Zoubeidi Charles L Sawyers Charles M Rudin Massimo Loda Timothy Thompson Mark A Rubin Abdul Tawab-Amiri William Dahut Peter S Nelson

Clin Cancer Res 2019 Dec 30;25(23):6916-6924. Epub 2019 Jul 30.

University of Washington, Fred Hutchinson Cancer Center, Seattle, Washington.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891154PMC
December 2019

Prostate-Specific Membrane Antigen Ligand Positron Emission Tomography in Men with Nonmetastatic Castration-Resistant Prostate Cancer.

Authors:
Wolfgang P Fendler Manuel Weber Amir Iravani Michael S Hofman Jérémie Calais Johannes Czernin Harun Ilhan Fred Saad Eric J Small Matthew R Smith Paola M Perez Thomas A Hope Isabel Rauscher Anil Londhe Angela Lopez-Gitlitz Shinta Cheng Tobias Maurer Ken Herrmann Matthias Eiber Boris Hadaschik

Clin Cancer Res 2019 Dec 11;25(24):7448-7454. Epub 2019 Sep 11.

University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1050DOI Listing
December 2019

How current reporting practices may mask differences: A call for examining cancer-specific demographic enrollment patterns in cancer treatment clinical trials.

Authors:
Hala T Borno Eric J Small Li Zhang Mindy C DeRouen Ann Griffin Joseph McGuire Charles J Ryan Robert A Hiatt Celia P Kaplan

Contemp Clin Trials Commun 2019 Dec 28;16:100476. Epub 2019 Oct 28.

University of California at San Francisco, Division of General Internal Medicine, United States.

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http://dx.doi.org/10.1016/j.conctc.2019.100476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915794PMC
December 2019

Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer.

Authors:
William S Chen Rahul Aggarwal Li Zhang Shuang G Zhao George V Thomas Tomasz M Beer David A Quigley Adam Foye Denise Playdle Jiaoti Huang Paul Lloyd Eric Lu Duanchen Sun Xiangnan Guan Matthew Rettig Martin Gleave Christopher P Evans Jack Youngren Lawrence True Primo Lara Vishal Kothari Zheng Xia Kim N Chi Robert E Reiter Christopher A Maher Felix Y Feng Eric J Small Joshi J Alumkal

Eur Urol 2019 Nov 28;76(5):562-571. Epub 2019 Mar 28.

Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1016/j.eururo.2019.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764911PMC
November 2019

Cabozantinib Versus Sunitinib for Untreated Patients with Advanced Renal Cell Carcinoma of Intermediate or Poor Risk: Subgroup Analysis of the Alliance A031203 CABOSUN trial.

Authors:
Daniel J George Colin Hessel Susan Halabi M Dror Michaelson Olwen Hahn Meghara Walsh Joel Picus Eric J Small Shaker Dakhil Darren R Feldman Milan Mangeshkar Christian Scheffold Michael J Morris Toni K Choueiri

Oncologist 2019 Nov 9;24(11):1497-1501. Epub 2019 Aug 9.

Dana-Farber/Partners CancerCare, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1634/theoncologist.2019-0316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853096PMC
November 2019

Hyperpolarized C-pyruvate MRI detects real-time metabolic flux in prostate cancer metastases to bone and liver: a clinical feasibility study.

Authors:
Hsin-Yu Chen Rahul Aggarwal Robert A Bok Michael A Ohliger Zi Zhu Philip Lee Jeremy W Gordon Mark van Criekinge Lucas Carvajal James B Slater Peder E Z Larson Eric J Small John Kurhanewicz Daniel B Vigneron

Prostate Cancer Prostatic Dis 2019 Nov 4. Epub 2019 Nov 4.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41391-019-0180-zDOI Listing
November 2019

Germline polymorphisms associated with impaired survival outcomes and somatic tumor alterations in advanced prostate cancer.

Authors:
William S Chen Eric L Feng Rahul Aggarwal Adam Foye Tomasz M Beer Joshi J Alumkal Martin Gleave Kim N Chi Robert E Reiter Matthew B Rettig Christopher P Evans Eric J Small Nima Sharifi Shuang G Zhao

Prostate Cancer Prostatic Dis 2019 Nov 19. Epub 2019 Nov 19.

Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41391-019-0188-4DOI Listing
November 2019

Relationship Between Metastasis-free Survival and Overall Survival in Patients With Nonmetastatic Castration-resistant Prostate Cancer.

Authors:
Matthew R Smith Maneesha Mehra Sandhya Nair Joe Lawson Eric J Small

Clin Genitourin Cancer 2019 Nov 6. Epub 2019 Nov 6.

Division of Hematology and Oncology, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1016/j.clgc.2019.10.030DOI Listing
November 2019

Phase I Study of CTT1057, an F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer.

Authors:
Spencer C Behr Rahul Aggarwal Henry F VanBrocklin Robert R Flavell Kenneth Gao Eric J Small Joseph Blecha Salma Jivan Thomas A Hope Jeffry P Simko John Kurhanewicz Susan M Noworolski Natalie J Korn Romelyn De Los Santos Matthew R Cooperberg Peter R Carroll Hao G Nguyen Kirsten L Greene Beatrice Langton-Webster Clifford E Berkman Youngho Seo

J Nucl Med 2019 Jul 21;60(7):910-916. Epub 2018 Nov 21.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.2967/jnumed.118.220715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604687PMC
July 2019

Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types.

Authors:
William S Chen Mohammed Alshalalfa Shuang G Zhao Yang Liu Brandon A Mahal David A Quigley Ting Wei Elai Davicioni Timothy R Rebbeck Philip W Kantoff Christopher A Maher Karen E Knudsen Eric J Small Paul L Nguyen Felix Y Feng

Clin Cancer Res 2019 Jul 22;25(14):4290-4299. Epub 2019 Apr 22.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0404DOI Listing
July 2019

Treatment of advanced renal cell carcinoma patients with cabozantinib, an oral multityrosine kinase inhibitor of MET, AXL and VEGF receptors.

Authors:
Arpita Desai Eric J Small

Future Oncol 2019 Jul 11;15(20):2337-2348. Epub 2019 Jun 11.

Department of Medicine, Division of Hematology/Oncology, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.2217/fon-2019-0021DOI Listing
July 2019

Whole-Genome and Transcriptional Analysis of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer Demonstrates Intraclass Heterogeneity.

Authors:
Rahul R Aggarwal David A Quigley Jiaoti Huang Li Zhang Tomasz M Beer Matthew B Rettig Rob E Reiter Martin E Gleave George V Thomas Adam Foye Denise Playdle Paul Lloyd Kim N Chi Christopher P Evans Primo N Lara Felix Y Feng Joshi J Alumkal Eric J Small

Mol Cancer Res 2019 06 27;17(6):1235-1240. Epub 2019 Mar 27.

University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-1101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548614PMC
June 2019

Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial.

Authors:
Wolfgang P Fendler Jeremie Calais Matthias Eiber Robert R Flavell Ashley Mishoe Felix Y Feng Hao G Nguyen Robert E Reiter Matthew B Rettig Shozo Okamoto Louise Emmett Helle D Zacho Harun Ilhan Axel Wetter Christoph Rischpler Heiko Schoder Irene A Burger Jeannine Gartmann Raven Smith Eric J Small Roger Slavik Peter R Carroll Ken Herrmann Johannes Czernin Thomas A Hope

JAMA Oncol 2019 Jun;5(6):856-863

Departments of Radiology and Biomedical Imaging and Pharmaceutical Chemistry, University of California San Francisco, San Francisco.

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http://dx.doi.org/10.1001/jamaoncol.2019.0096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567829PMC
June 2019

Management of recurrent prostate cancer after radiotherapy: long-term results from CALGB 9687 (Alliance), a prospective multi-institutional salvage prostatectomy series.

Authors:
James L Mohler Susan Halabi Stephen T Ryan Ali Al-Daghmin Mitchell H Sokoloff Gary D Steinberg Ben L Sanford James A Eastham Philip J Walther Michael J Morris Eric J Small

Prostate Cancer Prostatic Dis 2019 05 1;22(2):309-316. Epub 2018 Nov 1.

University of California at San Francisco, San Francisco, CA, CA60138, United States.

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http://www.nature.com/articles/s41391-018-0106-1
Publisher Site
http://dx.doi.org/10.1038/s41391-018-0106-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494708PMC
May 2019

Incidentally Detected Oropharyngeal Squamous Cell Carcinoma on 18F-Fluciclovine PET/CT.

Authors:
Kesav Raghavan Kwun Wah Wen Eric J Small Patrick Ha Robert R Flavell

Clin Nucl Med 2019 May;44(5):e367-e369

From the Division of Nuclear Medicine, Department of Radiology and Biomedical Imaging.

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http://dx.doi.org/10.1097/RLU.0000000000002507DOI Listing
May 2019

Prostate Cancer, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.

Authors:
James L Mohler Emmanuel S Antonarakis Andrew J Armstrong Anthony V D'Amico Brian J Davis Tanya Dorff James A Eastham Charles A Enke Thomas A Farrington Celestia S Higano Eric Mark Horwitz Michael Hurwitz Joseph E Ippolito Christopher J Kane Michael R Kuettel Joshua M Lang Jesse McKenney George Netto David F Penson Elizabeth R Plimack Julio M Pow-Sang Thomas J Pugh Sylvia Richey Mack Roach Stan Rosenfeld Edward Schaeffer Ahmad Shabsigh Eric J Small Daniel E Spratt Sandy Srinivas Jonathan Tward Dorothy A Shead Deborah A Freedman-Cass

J Natl Compr Canc Netw 2019 May;17(5):479-505

28National Comprehensive Cancer Network.

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http://dx.doi.org/10.6004/jnccn.2019.0023DOI Listing
May 2019

Germline and Somatic Mutations in Prostate Cancer for the Clinician.

Authors:
Heather H Cheng Alexandra O Sokolova Edward M Schaeffer Eric J Small Celestia S Higano

J Natl Compr Canc Netw 2019 May;17(5):515-521

aDivision of Medical Oncology, University of Washington, and.

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http://dx.doi.org/10.6004/jnccn.2019.7307DOI Listing
May 2019

Clinical and Genomic Implications of Luminal and Basal Subtypes Across Carcinomas.

Authors:
Shuang G Zhao William S Chen Rajdeep Das S Laura Chang Scott A Tomlins Jonathan Chou David A Quigley Ha X Dang Travis J Barnard Brandon A Mahal Ewan A Gibb Yang Liu Elai Davicioni Linda R Duska Edwin M Posadas Shruti Jolly Daniel E Spratt Paul L Nguyen Christopher A Maher Eric J Small Felix Y Feng

Clin Cancer Res 2019 04 20;25(8):2450-2457. Epub 2018 Dec 20.

Department of Radiation Oncology, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3121DOI Listing
April 2019

Itraconazole as a Noncastrating Treatment for Biochemically Recurrent Prostate Cancer: A Phase 2 Study.

Authors:
Mina Lee Haemin Hong Won Kim Li Zhang Terence W Friedlander Lawrence Fong Amy M Lin Eric J Small Xiao X Wei Tammy J Rodvelt Brigid Miralda Brian Stocksdale Charles J Ryan Rahul Aggarwal

Clin Genitourin Cancer 2019 Feb 24;17(1):e92-e96. Epub 2018 Sep 24.

University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2018.09.013DOI Listing
February 2019

Apalutamide and its use in the treatment of prostate cancer.

Authors:
Hala T Borno Eric J Small

Future Oncol 2019 Feb 14;15(6):591-599. Epub 2018 Nov 14.

Division of Hematology/Oncology, Department of Medicine, University of California at San Francisco, CA 94158, USA.

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https://www.futuremedicine.com/doi/10.2217/fon-2018-0546
Publisher Site
http://dx.doi.org/10.2217/fon-2018-0546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391625PMC
February 2019

Reply to A. Dalla Volta et al.

Authors:
Rahul Aggarwal Jiaoti Huang Joshi Alumkal Felix Y Feng Li Zhang Joshua M Stuart Eric J Small

J Clin Oncol 2019 02 17;37(4):351-352. Epub 2018 Dec 17.

Rahul Aggarwal, MD, University of California San Francisco, San Francisco, CA; Jiaoti Huang, MD, PhD, Duke University, Durham, NC; Joshi Alumkal, MD, Oregon Health Sciences University, Portland, OR; Felix Y. Feng, MD and Li Zhang, PhD, University of California San Francisco, San Francisco, CA; Joshua M. Stuart, PhD, University of California Santa Cruz, Santa Cruz, CA; and Eric J. Small, MD, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.18.01487DOI Listing
February 2019

Overall Survival of Black and White Men With Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel.

Authors:
Susan Halabi Sandipan Dutta Catherine M Tangen Mark Rosenthal Daniel P Petrylak Ian M Thompson Kim N Chi John C Araujo Christopher Logothetis David I Quinn Karim Fizazi Michael J Morris Mario A Eisenberger Daniel J George Johann S De Bono Celestia S Higano Ian F Tannock Eric J Small William Kevin Kelly

J Clin Oncol 2019 02 21;37(5):403-410. Epub 2018 Dec 21.

15 Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, PA.

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http://ascopubs.org/doi/10.1200/JCO.18.01279
Publisher Site
http://dx.doi.org/10.1200/JCO.18.01279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804881PMC
February 2019

Intertumoral Heterogeneity of 18F-FDG and 68Ga-PSMA Uptake in Prostate Cancer Pulmonary Metastases.

Authors:
Paola M Perez Thomas A Hope Spencer C Behr Annemieke van Zante Eric J Small Robert R Flavell

Clin Nucl Med 2019 Jan;44(1):e28-e32

From the Departments of Radiology and Biomedical Imaging.

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http://dx.doi.org/10.1097/RLU.0000000000002367DOI Listing
January 2019

A bilingual, Internet-based, targeted advertising campaign for prostate cancer clinical trials: Assessing the feasibility, acceptability, and efficacy of a novel recruitment strategy.

Authors:
Celia P Kaplan Adam Siegel Yan Leykin Nynikka R Palmer Hala Borno Jessica Bielenberg Jennifer Livaudais-Toman Charles Ryan Eric J Small

Contemp Clin Trials Commun 2018 Dec 15;12:60-67. Epub 2018 Aug 15.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, USA.

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http://dx.doi.org/10.1016/j.conctc.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158958PMC
December 2018

Apalutamide in the treatment of castrate-resistant prostate cancer: evidence from clinical trials.

Authors:
Vadim S Koshkin Eric J Small

Ther Adv Urol 2018 Dec 11;10(12):445-454. Epub 2018 Nov 11.

Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.

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http://journals.sagepub.com/doi/10.1177/1756287218811450
Publisher Site
http://dx.doi.org/10.1177/1756287218811450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295778PMC
December 2018

Corrigendum to 'Cabozantinib versus sunitinib as initial therapy for metastatic renal cell carcinoma of intermediate or poor risk (Alliance A031203 CABOSUN randomised trial): Progression-free survival by independent review and overall survival update' [Eur J Cancer 94 (May 2018) 115-125].

Authors:
Toni K Choueiri Colin Hessel Susan Halabi Ben Sanford M Dror Michaelson Olwen Hahn Meghara Walsh Thomas Olencki Joel Picus Eric J Small Shaker Dakhil Darren R Feldman Milan Mangeshkar Christian Scheffold Daniel George Michael J Morris

Eur J Cancer 2018 11 27;103:287. Epub 2018 Sep 27.

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.ejca.2018.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299293PMC
November 2018

Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival.

Authors:
Emmanuel S Antonarakis Eric J Small Daniel P Petrylak David I Quinn Adam S Kibel Nancy N Chang Erica Dearstyne Matt Harmon Dwayne Campogan Heather Haynes Tuyen Vu Nadeem A Sheikh Charles G Drake

Clin Cancer Res 2018 10 1;24(19):4662-4671. Epub 2018 Jun 1.

Columbia University Herbert Irving Comprehensive Cancer Center, Department of Urology, and the Columbia Center for Translational Immunology (CCTI), New York, New York.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-18-0638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481607PMC
October 2018

Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial.

Authors:
Fred Saad David Cella Ethan Basch Boris A Hadaschik Paul N Mainwaring Stéphane Oudard Julie N Graff Kelly McQuarrie Susan Li Stacie Hudgens Joe Lawson Angela Lopez-Gitlitz Margaret K Yu Matthew R Smith Eric J Small

Lancet Oncol 2018 10 10;19(10):1404-1416. Epub 2018 Sep 10.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/S1470-2045(18)30456-XDOI Listing
October 2018

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Authors:
David A Quigley Ha X Dang Shuang G Zhao Paul Lloyd Rahul Aggarwal Joshi J Alumkal Adam Foye Vishal Kothari Marc D Perry Adina M Bailey Denise Playdle Travis J Barnard Li Zhang Jin Zhang Jack F Youngren Marcin P Cieslik Abhijit Parolia Tomasz M Beer George Thomas Kim N Chi Martin Gleave Nathan A Lack Amina Zoubeidi Robert E Reiter Matthew B Rettig Owen Witte Charles J Ryan Lawrence Fong Won Kim Terence Friedlander Jonathan Chou Haolong Li Rajdeep Das Hui Li Ruhollah Moussavi-Baygi Hani Goodarzi Luke A Gilbert Primo N Lara Christopher P Evans Theodore C Goldstein Joshua M Stuart Scott A Tomlins Daniel E Spratt R Keira Cheetham Donavan T Cheng Kyle Farh Julian S Gehring Jörg Hakenberg Arnold Liao Philip G Febbo John Shon Brad Sickler Serafim Batzoglou Karen E Knudsen Housheng H He Jiaoti Huang Alexander W Wyatt Scott M Dehm Alan Ashworth Arul M Chinnaiyan Christopher A Maher Eric J Small Felix Y Feng

Cell 2018 10;175(3):889

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http://dx.doi.org/10.1016/j.cell.2018.10.019DOI Listing
October 2018

Targeting CD46 for both adenocarcinoma and neuroendocrine prostate cancer.

Authors:
Yang Su Yue Liu Christopher R Behrens Scott Bidlingmaier Nam-Kyung Lee Rahul Aggarwal Daniel W Sherbenou Alma L Burlingame Byron C Hann Jeffry P Simko Gayatri Premasekharan Pamela L Paris Marc A Shuman Youngho Seo Eric J Small Bin Liu

JCI Insight 2018 09 6;3(17). Epub 2018 Sep 6.

Department of Anesthesia.

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http://dx.doi.org/10.1172/jci.insight.121497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171802PMC
September 2018

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.

Authors:
Rahul Aggarwal Jiaoti Huang Joshi J Alumkal Li Zhang Felix Y Feng George V Thomas Alana S Weinstein Verena Friedl Can Zhang Owen N Witte Paul Lloyd Martin Gleave Christopher P Evans Jack Youngren Tomasz M Beer Matthew Rettig Christopher K Wong Lawrence True Adam Foye Denise Playdle Charles J Ryan Primo Lara Kim N Chi Vlado Uzunangelov Artem Sokolov Yulia Newton Himisha Beltran Francesca Demichelis Mark A Rubin Joshua M Stuart Eric J Small

J Clin Oncol 2018 08 9;36(24):2492-2503. Epub 2018 Jul 9.

Rahul Aggarwal, Li Zhang, Felix Y. Feng, Paul Lloyd, Jack Youngren, Adam Foye, Denise Playdle, Charles J. Ryan, and Eric J. Small, University of California San Francisco, San Francisco; Alana S. Weinstein, Verena Friedl, Can Zhang, Christopher K. Wong, Vlado Uzunangelov, Artem Sokolov, Yulia Newton, and Joshua M. Stuart, University of California Santa Cruz, Santa Cruz; Owen N. Witte and Matthew Rettig, University of California Los Angeles, Los Angeles; Christopher P. Evans and Primo Lara, University of California Davis, Davis, CA; Jiaoti Huang, Duke University, Durham, NC; Joshi J. Alumkal, George V. Thomas, and Tomasz M. Beer, Oregon Health Sciences University, Portland, OR; Martin Gleave and Kim N. Chi, University of British Columbia, Vancouver, British Columbia, Canada; Lawrence True, University of Washington, Seattle, WA; Himisha Beltran and Mark A. Rubin, Weill Cornell Medicine, New York, NY; and Francesca Demichelis, University of Trento, Trento, Italy.

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http://dx.doi.org/10.1200/JCO.2017.77.6880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366813PMC
August 2018

DNA Repair Gene Alterations and PARP Inhibitor Response in Patients With Metastatic Castration-Resistant Prostate Cancer.

Authors:
Eric Lu George V Thomas Yiyi Chen Alexander W Wyatt Paul Lloyd Jack Youngren David Quigley Raymond Bergan Shawna Bailey Tomasz M Beer Felix Y Feng Eric J Small Joshi J Alumkal

J Natl Compr Canc Netw 2018 08;16(8):933-937

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http://dx.doi.org/10.6004/jnccn.2018.7020DOI Listing
August 2018

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Authors:
David A Quigley Ha X Dang Shuang G Zhao Paul Lloyd Rahul Aggarwal Joshi J Alumkal Adam Foye Vishal Kothari Marc D Perry Adina M Bailey Denise Playdle Travis J Barnard Li Zhang Jin Zhang Jack F Youngren Marcin P Cieslik Abhijit Parolia Tomasz M Beer George Thomas Kim N Chi Martin Gleave Nathan A Lack Amina Zoubeidi Robert E Reiter Matthew B Rettig Owen Witte Charles J Ryan Lawrence Fong Won Kim Terence Friedlander Jonathan Chou Haolong Li Rajdeep Das Hui Li Ruhollah Moussavi-Baygi Hani Goodarzi Luke A Gilbert Primo N Lara Christopher P Evans Theodore C Goldstein Joshua M Stuart Scott A Tomlins Daniel E Spratt R Keira Cheetham Donavan T Cheng Kyle Farh Julian S Gehring Jörg Hakenberg Arnold Liao Philip G Febbo John Shon Brad Sickler Serafim Batzoglou Karen E Knudsen Housheng H He Jiaoti Huang Alexander W Wyatt Scott M Dehm Alan Ashworth Arul M Chinnaiyan Christopher A Maher Eric J Small Felix Y Feng

Cell 2018 07 19;174(3):758-769.e9. Epub 2018 Jul 19.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA, USA; Division of Hematology and Oncology, Department of Medicine, UCSF, San Francisco, CA, USA; Department of Radiation Oncology, UCSF, San Francisco, CA, USA; Department of Urology, UCSF, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425931PMC
July 2018

Clinical Variables Associated With Overall Survival in Metastatic Castration-Resistant Prostate Cancer Patients Treated With Sipuleucel-T Immunotherapy.

Authors:
Xiao X Wei Jaselle Perry Emily Chang Li Zhang Robert A Hiatt Charles J Ryan Eric J Small Lawrence Fong

Clin Genitourin Cancer 2018 06 27;16(3):184-190.e2. Epub 2017 Dec 27.

Division of Hematology/Oncology, University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA.

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http://dx.doi.org/10.1016/j.clgc.2017.12.004DOI Listing
June 2018

Apalutamide and Metastasis-free Survival in Prostate Cancer.

Authors:
Matthew R Smith Margaret K Yu Eric J Small

N Engl J Med 2018 06;378(26):2542

University of California San Francisco, San Francisco, CA

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http://www.nejm.org/doi/10.1056/NEJMc1806189
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http://dx.doi.org/10.1056/NEJMc1806189DOI Listing
June 2018

Cabozantinib versus sunitinib as initial therapy for metastatic renal cell carcinoma of intermediate or poor risk (Alliance A031203 CABOSUN randomised trial): Progression-free survival by independent review and overall survival update.

Authors:
Toni K Choueiri Colin Hessel Susan Halabi Ben Sanford M Dror Michaelson Olwen Hahn Meghara Walsh Thomas Olencki Joel Picus Eric J Small Shaker Dakhil Darren R Feldman Milan Mangeshkar Christian Scheffold Daniel George Michael J Morris

Eur J Cancer 2018 05 20;94:115-125. Epub 2018 Mar 20.

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.ejca.2018.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057479PMC
May 2018

Heterogeneous Flare in Prostate-specific Membrane Antigen Positron Emission Tomography Tracer Uptake with Initiation of Androgen Pathway Blockade in Metastatic Prostate Cancer.

Authors:
Rahul Aggarwal Xiao Wei Won Kim Eric J Small Charles J Ryan Peter Carroll Matthew Cooperberg Michael J Evans Thomas Hope

Eur Urol Oncol 2018 05 15;1(1):78-82. Epub 2018 May 15.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.euo.2018.03.010DOI Listing
May 2018

Low testosterone at first prostate-specific antigen failure and assessment of risk of death in men with unfavorable-risk prostate cancer treated on prospective clinical trials.

Authors:
Katelyn M Atkins Ming-Hui Chen Jing Wu Andrew A Renshaw Marian Loffredo Philip W Kantoff Eric J Small Anthony V D'Amico

Cancer 2018 04 20;124(7):1383-1390. Epub 2017 Dec 20.

Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.31204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034656PMC
April 2018

Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer.

Authors:
Matthew R Smith Fred Saad Simon Chowdhury Stéphane Oudard Boris A Hadaschik Julie N Graff David Olmos Paul N Mainwaring Ji Youl Lee Hiroji Uemura Angela Lopez-Gitlitz Géralyn C Trudel Byron M Espina Youyi Shu Youn C Park Wayne R Rackoff Margaret K Yu Eric J Small

N Engl J Med 2018 Apr 8;378(15):1408-1418. Epub 2018 Feb 8.

From the Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston (M.R.S.); Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montreal (F.S.); Guy's, King's and St. Thomas' Hospitals, Great Maze Pond, London (S.C.); Georges Pompidou Hospital, Paris (S.O.); University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany (B.A.H.); Veterans Affairs Portland Health Care System, Portland, and Knight Cancer Institute, Oregon Health and Science University, Portland (J.N.G.); Spanish National Cancer Research Center, Madrid, and Hospitales Universitarios Virgen de la Victoria y Regional, Institute of Biomedical Research in Malaga, Malaga - both in Spain (D.O.); Centre for Personalised Nanomedicine, University of Queensland, Brisbane, Australia (P.N.M.); St. Mary's Hospital of Catholic University, Seoul, South Korea (J.Y.L.); Yokohama City University Medical Center, Yokohama, Japan (H.U.); Janssen Research and Development, Los Angeles (A.L.-G., G.C.T., B.M.E., Y.S., Y.C.P., W.R.R., M.K.Y.); and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco (E.J.S.).

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http://dx.doi.org/10.1056/NEJMoa1715546DOI Listing
April 2018

Impact of Ga-PSMA-11 PET on Management in Patients with Biochemically Recurrent Prostate Cancer.

Authors:
Thomas A Hope Rahul Aggarwal Bryant Chee Dora Tao Kirsten L Greene Matthew R Cooperberg Felix Feng Albert Chang Charles J Ryan Eric J Small Peter R Carroll

J Nucl Med 2017 12 18;58(12):1956-1961. Epub 2017 May 18.

UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.

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http://jnm.snmjournals.org/lookup/doi/10.2967/jnumed.117.192
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http://dx.doi.org/10.2967/jnumed.117.192476DOI Listing
December 2017

High-Dose Abiraterone Acetate in Men With Castration Resistant Prostate Cancer.

Authors:
Terence W Friedlander Julie N Graff Kreshnik Zejnullahu Archana Anantharaman Li Zhang Rosa Paz Gayatri Premasekharan Carly Russell Yong Huang Won Kim Rahul R Aggarwal Amy M Lin Lawrence Fong Joshi J Alumkal Tomasz M Beer Nima Sharifi Mohammad Alyamani Ryan Dittamore Eric J Small Pamela L Paris Charles J Ryan

Clin Genitourin Cancer 2017 12 3;15(6):733-741.e1. Epub 2017 Jun 3.

Division of Genitourinary Medical Oncology, University of California, San Francisco, CA.

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http://dx.doi.org/10.1016/j.clgc.2017.05.026DOI Listing
December 2017

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer.

Authors:
Alexander W Wyatt Matti Annala Rahul Aggarwal Kevin Beja Felix Feng Jack Youngren Adam Foye Paul Lloyd Matti Nykter Tomasz M Beer Joshi J Alumkal George V Thomas Robert E Reiter Matthew B Rettig Christopher P Evans Allen C Gao Kim N Chi Eric J Small Martin E Gleave

J Natl Cancer Inst 2017 Dec;109(12)

Department of Urologic Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada; Institute of Biosciences and Medical Technology, University of Tampere, Tampere, Finland; Department of Medicine and Department of Radiation Oncology, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA; Oregon Health and Science University (OHSU) Knight Cancer Institute, Portland, OR; Department of Urology, University of California, Davis, School of Medicine, Sacremento, CA; Department of Medical Oncology, British Columbia Cancer Agency, Vancouver, Canada.

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http://dx.doi.org/10.1093/jnci/djx118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440274PMC
December 2017

Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of Reversion Mutations Associated with Resistance to PARP Inhibitors.

Authors:
David Quigley Joshi J Alumkal Alexander W Wyatt Vishal Kothari Adam Foye Paul Lloyd Rahul Aggarwal Won Kim Eric Lu Jacob Schwartzman Kevin Beja Matti Annala Rajdeep Das Morgan Diolaiti Colin Pritchard George Thomas Scott Tomlins Karen Knudsen Christopher J Lord Charles Ryan Jack Youngren Tomasz M Beer Alan Ashworth Eric J Small Felix Y Feng

Cancer Discov 2017 09 27;7(9):999-1005. Epub 2017 Apr 27.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, California.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8290.CD-17-0146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581695PMC
September 2017

Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer.

Authors:
Rahul Aggarwal Spencer C Behr Pamela L Paris Charles Truillet Matthew F L Parker Loc T Huynh Junnian Wei Byron Hann Jack Youngren Jiaoti Huang Gayatri Premasekharan Nimna Ranatunga Emily Chang Kenneth T Gao Charles J Ryan Eric J Small Michael J Evans

Mol Cancer Res 2017 09 7;15(9):1221-1229. Epub 2017 Jun 7.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581675PMC
September 2017

Redefining Hormonal Therapy for Advanced Prostate Cancer: Results from the LATITUDE and STAMPEDE Studies.

Authors:
Eric J Small

Cancer Cell 2017 09;32(3):392

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http://dx.doi.org/10.1016/j.ccell.2017.08.009DOI Listing
September 2017

Optimal MRI sequences for Ga-PSMA-11 PET/MRI in evaluation of biochemically recurrent prostate cancer.

Authors:
Spencer T Lake Kirsten L Greene Antonio C Westphalen Spencer C Behr Ronald Zagoria Eric J Small Peter R Carroll Thomas A Hope

EJNMMI Res 2017 Sep 19;7(1):77. Epub 2017 Sep 19.

Department of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue - 0628, San Francisco, CA, 94143-0628, USA.

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http://ejnmmires.springeropen.com/articles/10.1186/s13550-01
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http://dx.doi.org/10.1186/s13550-017-0327-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605480PMC
September 2017

Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer.

Authors:
Jennifer Podolak Kristi Eilers Timothy Newby Rachel Slottke Erin Tucker Susan B Olson Hui-Wen Lue Jack Youngren Rahul Aggarwal Eric J Small Julie N Graff Joshi J Alumkal Tomasz M Beer George V Thomas

Oncotarget 2017 Sep 13;8(42):71447-71455. Epub 2017 Mar 13.

Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.

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http://dx.doi.org/10.18632/oncotarget.16169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641061PMC
September 2017

CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield.

Authors:
Michael G Holmes Erik Foss Gabby Joseph Adam Foye Brooke Beckett Daria Motamedi Jack Youngren George V Thomas Jiaoti Huang Rahul Aggarwal Joshi J Alumkal Tomasz M Beer Eric J Small Thomas M Link

J Vasc Interv Radiol 2017 Aug 24;28(8):1073-1081.e1. Epub 2017 May 24.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Avenue, S-261, San Francisco, CA 94143-0628.

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http://dx.doi.org/10.1016/j.jvir.2017.04.019DOI Listing
August 2017

Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair-deficient Prostate Cancer.

Authors:
Matti Annala Werner J Struss Evan W Warner Kevin Beja Gillian Vandekerkhove Amanda Wong Daniel Khalaf Irma-Liisa Seppälä Alan So Gregory Lo Rahul Aggarwal Eric J Small Matti Nykter Martin E Gleave Kim N Chi Alexander W Wyatt

Eur Urol 2017 07 1;72(1):34-42. Epub 2017 Mar 1.

Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.02.023DOI Listing
July 2017

Clinical Outcomes from Androgen Signaling-directed Therapy after Treatment with Abiraterone Acetate and Prednisone in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302.

Authors:
Matthew R Smith Fred Saad Dana E Rathkopf Peter F A Mulders Johann S de Bono Eric J Small Neal D Shore Karim Fizazi Thian Kheoh Jinhui Li Peter De Porre Mary B Todd Margaret K Yu Charles J Ryan

Eur Urol 2017 07 15;72(1):10-13. Epub 2017 Mar 15.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.eururo.2017.03.007DOI Listing
July 2017

Tackling non-metastatic castration-resistant prostate cancer: special considerations in treatment.

Authors:
Archana Anantharaman Eric J Small

Expert Rev Anticancer Ther 2017 07 31;17(7):625-633. Epub 2017 May 31.

a Department of Medicine , University of California, San Francisco , San Francisco , CA , USA.

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http://dx.doi.org/10.1080/14737140.2017.1333903DOI Listing
July 2017

Redefining Hormonal Therapy for Advanced Prostate Cancer: Results from the LATITUDE and STAMPEDE Studies.

Authors:
Eric J Small

Cancer Cell 2017 07;32(1):6-8

University of California, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.06.007DOI Listing
July 2017

Molecular Testing in Patients With Castration-Resistant Prostate Cancer and Its Impact on Clinical Decision Making.

Authors:
Derrick L Tao Shawna Bailey Tomasz M Beer Erik Foss Brooke Beckett Alice Fung Bryan R Foster Alexander Guimaraes Jeremy P Cetnar Julie N Graff Kristine M Eilers Eric J Small Christopher L Corless George V Thomas Joshi J Alumkal

JCO Precis Oncol 2017 28;1. Epub 2017 Jun 28.

Derrick L. Tao, Shawna Bailey, Tomasz M. Beer, Erik Foss, Brooke Beckett, Alice Fung, Bryan R. Foster, Alexander Guimaraes, Jeremy P. Cetnar, Julie N. Graff, Kristine M. Eilers, Christopher L. Corless, George V. Thomas, and Joshi J. Alumkal, Oregon Health & Science University, Portland, OR; and Eric J. Small, University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/PO.16.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812573PMC
June 2017

Emerging Categories of Disease in Advanced Prostate Cancer and Their Therapeutic Implications.

Authors:
Rahul R Aggarwal Felix Y Feng Eric J Small

Oncology (Williston Park) 2017 06;31(6):467-74

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June 2017

Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302.

Authors:
Johann S de Bono Matthew R Smith Fred Saad Dana E Rathkopf Peter F A Mulders Eric J Small Neal D Shore Karim Fizazi Peter De Porre Thian Kheoh Jinhui Li Mary B Todd Charles J Ryan Thomas W Flaig

Eur Urol 2017 04 9;71(4):656-664. Epub 2016 Jul 9.

University of Colorado Cancer Center, Aurora, CO, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03022838163038
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http://dx.doi.org/10.1016/j.eururo.2016.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609503PMC
April 2017

A multicenter phase I study of cabazitaxel, mitoxantrone, and prednisone for chemotherapy-naïve patients with metastatic castration-resistant prostate cancer: A department of defense prostate cancer clinical trials consortium study.

Authors:
Rahul Aggarwal Alan Bryce Charles J Ryan Andrea Harzstark Christina Derleth Won Kim Terence Friedlander Amy M Lin Tammy Rodvelt-Bagchi Mallika Dhawan Li Zhang Mina Lee Eric Siebeneck Jeffrey Hough Eric J Small

Urol Oncol 2017 04 1;35(4):149.e7-149.e13. Epub 2017 Feb 1.

Department of Medicine, Division of Hematology/Oncology, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA.

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http://dx.doi.org/10.1016/j.urolonc.2016.11.005DOI Listing
April 2017

Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial.

Authors:
Toni K Choueiri Susan Halabi Ben L Sanford Olwen Hahn M Dror Michaelson Meghara K Walsh Darren R Feldman Thomas Olencki Joel Picus Eric J Small Shaker Dakhil Daniel J George Michael J Morris

J Clin Oncol 2017 02 14;35(6):591-597. Epub 2016 Nov 14.

Toni K. Choueiri and Meghara K. Walsh, Dana-Farber Cancer Institute; M. Dror Michaelson, Massachusetts General Hospital Cancer Center, Boston, MA; Susan Halabi and Ben L. Sanford, Alliance Statistics and Data Center and Duke University; Daniel J. George, Duke Cancer Institute, Duke University Medical Center, Durham, NC; Olwen Hahn, Alliance Protocol Operations Office, Chicago, IL; Darren R. Feldman and Michael J. Morris, Memorial Sloan Kettering Cancer Center, New York, NY; Thomas Olencki, Ohio State University Medical Center, Columbus, OH; Joel Picus, Siteman Cancer Center, Washington University School of Medicine, St Louis, MO; Eric J. Small, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA; and Shaker Dakhil, University of Kansas Wichita, Wichita, KS.

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http://dx.doi.org/10.1200/JCO.2016.70.7398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455807PMC
February 2017

68Ga-PSMA-11 PET Imaging of Response to Androgen Receptor Inhibition: First Human Experience.

Authors:
Thomas A Hope Charles Truillet Eric C Ehman Ali Afshar-Oromieh Rahul Aggarwal Charles J Ryan Peter R Carroll Eric J Small Michael J Evans

J Nucl Med 2017 Jan 22;58(1):81-84. Epub 2016 Sep 22.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.2967/jnumed.116.181800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209643PMC
January 2017

A Feasibility Study Showing [Ga]Citrate PET Detects Prostate Cancer.

Authors:
Spencer C Behr Rahul Aggarwal Youngho Seo Carina M Aparici Emily Chang Kenneth T Gao Dora H Tao Eric J Small Michael J Evans

Mol Imaging Biol 2016 12;18(6):946-951

Department of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Lobby 6, Suite 350, San Francisco, CA, 94107, USA.

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http://dx.doi.org/10.1007/s11307-016-0966-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430569PMC
December 2016

Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer: Update on the Stand Up 2 Cancer/Prostate Cancer Foundation-Supported West Coast Prostate Cancer Dream Team.

Authors:
Rahul Aggarwal Tomasz M Beer Martin Gleave Joshua M Stuart Matthew Rettig Christopher P Evans Jack Youngren Joshi J Alumkal Jiaoti Huang George Thomas Owen Witte Eric J Small

Eur Urol Focus 2016 Dec 14;2(5):469-471. Epub 2016 Nov 14.

University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.euf.2016.10.011DOI Listing
December 2016

Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer.

Authors:
Xiao X Wei Stephen Chan Serena Kwek Jera Lewis Vinh Dao Li Zhang Matthew R Cooperberg Charles J Ryan Amy M Lin Terence W Friedlander Brian Rini Christopher Kane Jeffry P Simko Peter R Carroll Eric J Small Lawrence Fong

Cancer Immunol Res 2016 11 29;4(11):948-958. Epub 2016 Sep 29.

University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, California.

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http://dx.doi.org/10.1158/2326-6066.CIR-16-0042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115633PMC
November 2016

Prospects for the use of ipilimumab in treating advanced prostate cancer.

Authors:
Xiao X Wei Lawrence Fong Eric J Small

Expert Opin Biol Ther 2016 25;16(3):421-32. Epub 2016 Jan 25.

a Division of Hematology and Oncology, UCSF Helen Diller Family Comprehensive Cancer Center , University of California, San Francisco , San Francisco , CA , USA.

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http://dx.doi.org/10.1517/14712598.2016.1136284DOI Listing
October 2016

Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.

Authors:
Daniel L Hertz Kouros Owzar Sherrie Lessans Claudia Wing Chen Jiang William Kevin Kelly Jai Patel Susan Halabi Yoichi Furukawa Heather E Wheeler Alexander B Sibley Cameron Lassiter Lois Weisman Dorothy Watson Stefanie D Krens Flora Mulkey Cynthia L Renn Eric J Small Phillip G Febbo Ivo Shterev Deanna L Kroetz Paula N Friedman John F Mahoney Michael A Carducci Michael J Kelley Yusuke Nakamura Michiaki Kubo Susan G Dorsey M Eileen Dolan Michael J Morris Mark J Ratain Howard L McLeod

Clin Cancer Res 2016 Oct 3;22(19):4890-4900. Epub 2016 May 3.

UNC Institute for Pharmacogenomics and Individualized Therapy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Personalized Medicine Institute, Moffitt Cancer Center, Tampa, Florida.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050068PMC
http://dx.doi.org/10.1158/1078-0432.CCR-15-2823DOI Listing
October 2016

An improved CTC isolation scheme for pairing with downstream genomics: Demonstrating clinical utility in metastatic prostate, lung and pancreatic cancer.

Authors:
Gayatri Premasekharan Elizabeth Gilbert Ross A Okimoto Ashiya Hamirani Karla J Lindquist Vy T Ngo Ritu Roy Jeffrey Hough Matthew Edwards Rosa Paz Adam Foye Riddhi Sood Kirsten A Copren Matthew Gubens Eric J Small Trever G Bivona Eric A Collisson Terence W Friedlander Pamela L Paris

Cancer Lett 2016 09 22;380(1):144-52. Epub 2016 Jun 22.

Department of Urology, University of California, San Francisco (UCSF), San Francisco, CA, USA; Division of Hematology & Oncology, University of California, San Francisco (UCSF), San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.06.017DOI Listing
September 2016

Prostate Cancer Immunotherapy with Sipuleucel-T: Current Standards and Future Directions.

Authors:
Xiao X Wei Lawrence Fong Eric J Small

Expert Rev Vaccines 2015 21;14(12):1529-41. Epub 2015 Oct 21.

a UCSF Helen Diller Family Comprehensive Cancer Center , University of California, San Francisco , San Francisco , CA , USA.

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http://dx.doi.org/10.1586/14760584.2015.1099437DOI Listing
August 2016

Prior Endocrine Therapy Impact on Abiraterone Acetate Clinical Efficacy in Metastatic Castration-resistant Prostate Cancer: Post-hoc Analysis of Randomised Phase 3 Studies.

Authors:
Joaquim Bellmunt Thian Kheoh Margaret K Yu Matthew R Smith Eric J Small Peter F A Mulders Karim Fizazi Dana E Rathkopf Fred Saad Howard I Scher Mary-Ellen Taplin Ian D Davis Dirk Schrijvers Andrew Protheroe Arturo Molina Peter De Porre Thomas W Griffin Johann S de Bono Charles J Ryan Stéphane Oudard

Eur Urol 2016 05 24;69(5):924-32. Epub 2015 Oct 24.

Georges Pompidou Hospital, University René Descartes, Paris, France.

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http://dx.doi.org/10.1016/j.eururo.2015.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465643PMC
May 2016

Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer.

Authors:
Susan Halabi William Kevin Kelly Hua Ma Haojin Zhou Nicole C Solomon Karim Fizazi Catherine M Tangen Mark Rosenthal Daniel P Petrylak Maha Hussain Nicholas J Vogelzang Ian M Thompson Kim N Chi Johann de Bono Andrew J Armstrong Mario A Eisenberger Abderrahim Fandi Shaoyi Li John C Araujo Christopher J Logothetis David I Quinn Michael J Morris Celestia S Higano Ian F Tannock Eric J Small

J Clin Oncol 2016 05 7;34(14):1652-9. Epub 2016 Mar 7.

Susan Halabi, Hua Ma, Nicole C. Solomon, and Andrew J. Armstrong, Duke University, Durham, NC; William Kevin Kelly, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA; Haojin Zhou, Merck, Beijing, China; Karim Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif, France; Catherine M. Tangen, Southwest Oncology Group Statistical Center; Mark Rosenthal, Royal Melbourne Hospital, Melbourne, Victoria, Australia; Daniel P. Petrylak, Yale Cancer Center, New Haven, CT; Maha Hussain, University of Michigan, Ann Arbor, MI; Nicholas J. Vogelzang, US Oncology, Las Vegas, NV; Ian M. Thompson, University of Texas at San Antonio, San Antonio; John C. Araujo and Christopher J. Logothetis, The University of Texas MD Anderson Cancer Center, Houston, TX; Kim N. Chi, British Columbia Cancer Agency-Vancouver Cancer Centre, Vancouver, British Columbia; Ian F. Tannock, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada; Johann de Bono, Institute for Cancer Research, Royal Marsden Hospital, Sutton, Surrey, United Kingdom; Mario A. Eisenberger, Johns Hopkins University-School of Medicine, Oncology Center, Baltimore, MD; Abderrahim Fandi and Shaoyi Li, Celgene Corporation, Summit, NJ; David I. Quinn, University of Southern California Norris Cancer Center, Los Angeles; Eric J. Small, University of California San Francisco, San Francisco, CA; Celestia S. Higano, University of Washington, Seattle, WA; and Michael J. Morris, Memorial Sloan-Kettering Cancer Center New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2015.65.7270
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http://dx.doi.org/10.1200/JCO.2015.65.7270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872320PMC
May 2016

Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.

Authors:
Howard I Scher Michael J Morris Walter M Stadler Celestia Higano Ethan Basch Karim Fizazi Emmanuel S Antonarakis Tomasz M Beer Michael A Carducci Kim N Chi Paul G Corn Johann S de Bono Robert Dreicer Daniel J George Elisabeth I Heath Maha Hussain Wm Kevin Kelly Glenn Liu Christopher Logothetis David Nanus Mark N Stein Dana E Rathkopf Susan F Slovin Charles J Ryan Oliver Sartor Eric J Small Matthew Raymond Smith Cora N Sternberg Mary-Ellen Taplin George Wilding Peter S Nelson Lawrence H Schwartz Susan Halabi Philip W Kantoff Andrew J Armstrong

J Clin Oncol 2016 Apr 22;34(12):1402-18. Epub 2016 Feb 22.

Howard I. Scher, Michael J. Morris, Dana E. Rathkopf, and Susan F. Slovin, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College; David Nanus, NewYork Presbyterian Weill Cornell Medical Center; Lawrence W. Schwartz, NewYork Presbyterian Columbia University Medical Center, New York, NY; Walter M. Stadler, University of Chicago Medicine, Chicago, IL; Celestina Higano and Peter S. Nelson, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Ethan Basch, University of North Carolina at Chapel Hill, Chapel Hill, NC; Emmanual S. Antonarakis and Michael A. Carducci, Johns Hopkins University School of Medicine, Baltimore, MD; Tomasz M. Beer, Oregon Health and Science University, Portland, OR; Paul G. Corn and Christopher Logothetis, MD Anderson Cancer Center, Houston, TX; Robert Dreicer, University of Virginia School of Medicine, Charlottesville, VA; Daniel J. George, Susan Halabi, and Andrew J. Armstrong, Duke University and Duke Cancer Institute, Durham, NC; Elisabeth I. Heath, Wayne State University Karmanos Cancer Institute, Detroit; and Maha Hussain, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Wm. Kevin Kelly, Sidney Kimmel School of Medicine at Thomas Jefferson University, Philadelphia, PA; Glenn Liu and George Wilding, University of Wisconsin Carbone Cancer Center, Madison, WI; Mark N. Stein, The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ; Charles S. Ryan and Eric J. Small, University of California Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; Oliver Sartor, Tulane School of Medicine, New Orleans, LA; Matthew Raymond Smith, Massachusetts General Hospital Cancer Center and Harvard Medical School; Mary-Ellen Taplin and Philip W. Kantoff, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA; Karim Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif, Franc

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http://dx.doi.org/10.1200/JCO.2015.64.2702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872347PMC
April 2016

Prostate Cancer, Version 1.2016.

Authors:
James L Mohler Andrew J Armstrong Robert R Bahnson Anthony Victor D'Amico Brian J Davis James A Eastham Charles A Enke Thomas A Farrington Celestia S Higano Eric M Horwitz Michael Hurwitz Christopher J Kane Mark H Kawachi Michael Kuettel Richard J Lee Joshua J Meeks David F Penson Elizabeth R Plimack Julio M Pow-Sang David Raben Sylvia Richey Mack Roach Stan Rosenfeld Edward Schaeffer Ted A Skolarus Eric J Small Guru Sonpavde Sandy Srinivas Seth A Strope Jonathan Tward Dorothy A Shead Deborah A Freedman-Cass

J Natl Compr Canc Netw 2016 01;14(1):19-30

National Comprehensive Cancer Network

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http://dx.doi.org/10.6004/jnccn.2016.0004DOI Listing
January 2016

Optimal timing of sipuleucel-T treatment in metastatic castration-resistant prostate cancer.

Authors:
E David Crawford Daniel P Petrylak Celestia S Higano Adam S Kibel Philip W Kantoff Eric J Small Neal D Shore Anna Ferrari

Can J Urol 2015 Dec;22(6):8048-55

University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

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December 2015

Knowledge and attitudes regarding clinical trials and willingness to participate among prostate cancer patients.

Authors:
Celia P Kaplan Anna Maria Nápoles Steven Narine Steven Gregorich Jennifer Livaudais-Toman Tung Nguyen Yan Leykin Mack Roach Eric J Small

Contemp Clin Trials 2015 Nov 3;45(Pt B):443-448. Epub 2015 Oct 3.

Helen Diller Family Comprehensive Cancer Center,University of CaliforniaSan Francisco, USA; Department of Medicine, Division of Hematology and Oncology,University of CaliforniaSan Francisco, USA.

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http://dx.doi.org/10.1016/j.cct.2015.09.023DOI Listing
November 2015

A Molecular Model for Predicting Overall Survival in Patients with Metastatic Clear Cell Renal Carcinoma: Results from CALGB 90206 (Alliance).

Authors:
Hyung L Kim Susan Halabi Ping Li Greg Mayhew Jeff Simko Andrew B Nixon Eric J Small Brian Rini Michael J Morris Mary-Ellen Taplin Daniel George

EBioMedicine 2015 Nov 8;2(11):1814-20. Epub 2015 Sep 8.

Department of Biostatistics and Bioinformatics, and Alliance Statistics and Data Center, Duke University, Durham, NC, United States.

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http://dx.doi.org/10.1016/j.ebiom.2015.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740313PMC
November 2015

Impact of bone-targeted therapies in chemotherapy-naïve metastatic castration-resistant prostate cancer patients treated with abiraterone acetate: post hoc analysis of study COU-AA-302.

Authors:
Fred Saad Neal Shore Hendrik Van Poppel Dana E Rathkopf Matthew R Smith Johann S de Bono Christopher J Logothetis Paul de Souza Karim Fizazi Peter F A Mulders Paul Mainwaring John D Hainsworth Tomasz M Beer Scott North Yves Fradet Thomas A Griffin Peter De Porre Anil Londhe Thian Kheoh Eric J Small Howard I Scher Arturo Molina Charles J Ryan

Eur Urol 2015 Oct 16;68(4):570-7. Epub 2015 May 16.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056561PMC
http://dx.doi.org/10.1016/j.eururo.2015.04.032DOI Listing
October 2015

A Randomized Phase II Trial of Sipuleucel-T with Concurrent versus Sequential Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer.

Authors:
Eric J Small Raymond S Lance Thomas A Gardner Lawrence I Karsh Lawrence Fong Candice McCoy Todd DeVries Nadeem A Sheikh Debraj GuhaThakurta Nancy Chang Charles H Redfern Neal D Shore

Clin Cancer Res 2015 Sep 29;21(17):3862-9. Epub 2015 Apr 29.

Carolina Urologic Research Center, Myrtle Beach, South Carolina.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0079DOI Listing
September 2015

Preexisting Levels of CD4 T Cells Expressing PD-1 Are Related to Overall Survival in Prostate Cancer Patients Treated with Ipilimumab.

Authors:
Serena S Kwek Jera Lewis Li Zhang Vivian Weinberg Samantha K Greaney Andrea L Harzstark Amy M Lin Charles J Ryan Eric J Small Lawrence Fong

Cancer Immunol Res 2015 Sep 12;3(9):1008-16. Epub 2015 May 12.

Division of Hematology/Oncology, University of California, San Francisco, California. UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561203PMC
September 2015

Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome.

Authors:
Debraj GuhaThakurta Nadeem A Sheikh Li-Qun Fan Harini Kandadi T Craig Meagher Simon J Hall Philip W Kantoff Celestia S Higano Eric J Small Thomas A Gardner Kate Bailey Tuyen Vu Todd DeVries James B Whitmore Mark W Frohlich James B Trager Charles G Drake

Clin Cancer Res 2015 Aug 3;21(16):3619-30. Epub 2015 Feb 3.

Johns Hopkins University School of Medicine, the Brady Urological Institute, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868054PMC
August 2015

Intermittent Chemotherapy as a Platform for Testing Novel Agents in Patients With Metastatic Castration-Resistant Prostate Cancer: A Department of Defense Prostate Cancer Clinical Trials Consortium Randomized Phase II Trial of Intermittent Docetaxel With Prednisone With or Without Maintenance GM-CSF.

Authors:
Rahul R Aggarwal Tomasz M Beer Vivian K Weinberg Celestia Higano Mary-Ellen Taplin Charles J Ryan Amy M Lin Joshi Alumkal Julie N Graff Luke T Nordquist Isheen Herrera Eric J Small

Clin Genitourin Cancer 2015 Jun 9;13(3):e191-8. Epub 2014 Dec 9.

Department of Medicine, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1016/j.clgc.2014.12.004DOI Listing
June 2015

Progression-free survival: does a correlation with survival justify its role as a surrogate clinical endpoint?

Authors:
Susan Halabi Brian I Rini Bernard Escudier Walter M Stadler Eric J Small

Cancer 2015 Jun 11;121(11):1906. Epub 2015 Feb 11.

Department of Urology, University of California at San Francisco, San Francisco, California.

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http://dx.doi.org/10.1002/cncr.29252DOI Listing
June 2015

Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer.

Authors:
Arun A Azad Stanislav V Volik Alexander W Wyatt Anne Haegert Stephane Le Bihan Robert H Bell Shawn A Anderson Brian McConeghy Robert Shukin Jenny Bazov Jack Youngren Pamela Paris George Thomas Eric J Small Yuzhuo Wang Martin E Gleave Colin C Collins Kim N Chi

Clin Cancer Res 2015 May 23;21(10):2315-24. Epub 2015 Feb 23.

Vancouver Prostate Centre, Vancouver, British Columbia, Canada. Department of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada. University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2666DOI Listing
May 2015

Bevacizumab and the risk of arterial and venous thromboembolism in patients with metastatic, castration-resistant prostate cancer treated on Cancer and Leukemia Group B (CALGB) 90401 (Alliance).

Authors:
Jai N Patel Chen Jiang Daniel L Hertz Flora A Mulkey Kouros Owzar Susan Halabi Mark J Ratain Paula N Friedman Eric J Small Michael A Carducci John F Mahoney Michael J Kelley Michael J Morris William K Kelly Howard L McLeod

Cancer 2015 Apr 21;121(7):1025-31. Epub 2014 Nov 21.

Levine Cancer Institute, Carolinas HealthCare System, Charlotte, North Carolina.

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http://dx.doi.org/10.1002/cncr.29169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368497PMC
April 2015

Radiographic progression-free survival as a response biomarker in metastatic castration-resistant prostate cancer: COU-AA-302 results.

Authors:
Michael J Morris Arturo Molina Eric J Small Johann S de Bono Christopher J Logothetis Karim Fizazi Paul de Souza Philip W Kantoff Celestia S Higano Jinhui Li Thian Kheoh Steven M Larson Shannon L Matheny Vahid Naini Tomasz Burzykowski Thomas W Griffin Howard I Scher Charles J Ryan

J Clin Oncol 2015 Apr 26;33(12):1356-63. Epub 2015 Jan 26.

Michael J. Morris, Steven M. Larson, and Howard I. Scher, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY; Arturo Molina, Thian Kheoh, Shannon L. Matheny, Vahid Naini, and Thomas W. Griffin, Janssen Research & Development, Los Angeles; Eric J. Small and Charles J. Ryan, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA; Johann S. de Bono, Institute for Cancer Research and Royal Marsden Hospital, Sutton, United Kingdom; Christopher J. Logothetis, MD Anderson Cancer Center, Houston, TX; Karim Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif, France; Paul de Souza, University of Western Sydney School of Medicine, Ingham Institute, Liverpool, New South Wales, Australia; Philip W. Kantoff, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; Celestia S. Higano, University of Washington, Seattle, WA; Jinhui Li, Janssen Research & Development, Raritan, NJ; and Tomasz Burzykowski, International Drug Development Institute, Louvain-la-Neuve, Belgium.

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http://dx.doi.org/10.1200/JCO.2014.55.3875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881370PMC
April 2015

Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study.

Authors:
Charles J Ryan Matthew R Smith Karim Fizazi Fred Saad Peter F A Mulders Cora N Sternberg Kurt Miller Christopher J Logothetis Neal D Shore Eric J Small Joan Carles Thomas W Flaig Mary-Ellen Taplin Celestia S Higano Paul de Souza Johann S de Bono Thomas W Griffin Peter De Porre Margaret K Yu Youn C Park Jinhui Li Thian Kheoh Vahid Naini Arturo Molina Dana E Rathkopf

Lancet Oncol 2015 Feb 16;16(2):152-60. Epub 2015 Jan 16.

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1016/S1470-2045(14)71205-7DOI Listing
February 2015

Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens.

Authors:
Won Kim Li Zhang John H Wilton Gerald Fetterly James L Mohler Vivian Weinberg Allison Morse Russell Z Szmulewitz Terence W Friedlander Lawrence Fong Amy M Lin Andrea L Harzstark Arturo Molina Eric J Small Charles J Ryan

Clin Cancer Res 2014 Dec 21;20(24):6269-76. Epub 2014 Oct 21.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277885PMC
December 2014

Updated interim efficacy analysis and long-term safety of abiraterone acetate in metastatic castration-resistant prostate cancer patients without prior chemotherapy (COU-AA-302).

Authors:
Dana E Rathkopf Matthew R Smith Johann S de Bono Christopher J Logothetis Neal D Shore Paul de Souza Karim Fizazi Peter F A Mulders Paul Mainwaring John D Hainsworth Tomasz M Beer Scott North Yves Fradet Hendrik Van Poppel Joan Carles Thomas W Flaig Eleni Efstathiou Evan Y Yu Celestia S Higano Mary-Ellen Taplin Thomas W Griffin Mary B Todd Margaret K Yu Youn C Park Thian Kheoh Eric J Small Howard I Scher Arturo Molina Charles J Ryan Fred Saad

Eur Urol 2014 Nov 6;66(5):815-25. Epub 2014 Mar 6.

CRCHUM, University of Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1016/j.eururo.2014.02.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418928PMC
November 2014

Reply to F. Valcamonico et al.

Authors:
Matthew R Smith Susan Halabi Eric J Small

J Clin Oncol 2014 Nov 15;32(32):3685. Epub 2014 Sep 15.

University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2014.57.3808DOI Listing
November 2014

Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer.

Authors:
Lawrence Fong Peter Carroll Vivian Weinberg Stephen Chan Jera Lewis John Corman Christopher L Amling Robert A Stephenson Jeffrey Simko Nadeem A Sheikh Robert B Sims Mark W Frohlich Eric J Small

J Natl Cancer Inst 2014 Nov 24;106(11). Epub 2014 Sep 24.

University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA (LF, PC, VW, SC, JL, JS, EJS); Virginia Mason Medical Center, Seattle, WA (JC); Oregon Health & Science University, Portland, OR (CLA); University of Utah School of Medicine, Salt Lake City, UT (RAS); Dendreon Corporation, Seattle, WA (NAS, RBS, MWF).

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http://dx.doi.org/10.1093/jnci/dju268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241888PMC
November 2014

Can targeting the androgen receptor in localized prostate cancer provide insights into why men with metastatic castration-resistant prostate cancer die?

Authors:
Eric J Small

J Clin Oncol 2014 Nov 13;32(33):3689-91. Epub 2014 Oct 13.

University of California, San Francisco, San Francisco, CA

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http://dx.doi.org/10.1200/JCO.2014.57.8534DOI Listing
November 2014

Response to subsequent docetaxel in a patient cohort with metastatic castration-resistant prostate cancer after abiraterone acetate treatment.

Authors:
Rahul Aggarwal Anna Harris Carl Formaker Eric J Small Arturo Molina Thomas W Griffin Charles J Ryan

Clin Genitourin Cancer 2014 Oct 28;12(5):e167-72. Epub 2014 Mar 28.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1016/j.clgc.2014.03.010DOI Listing
October 2014

A transient increase in eosinophils is associated with prolonged survival in men with metastatic castration-resistant prostate cancer who receive sipuleucel-T.

Authors:
Douglas G McNeel Thomas A Gardner Celestia S Higano Philip W Kantoff Eric J Small Mark H Wener Robert B Sims Todd DeVries Nadeem A Sheikh Robert Dreicer

Cancer Immunol Res 2014 Oct 4;2(10):988-99. Epub 2014 Sep 4.

Department of Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185225PMC
October 2014

Small-cell/neuroendocrine prostate cancer: a growing threat?

Authors:
Rahul R Aggarwal Eric J Small

Oncology (Williston Park) 2014 Oct;28(10):838-40

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October 2014

Prostate cancer, version 2.2014.

Authors:
James L Mohler Philip W Kantoff Andrew J Armstrong Robert R Bahnson Michael Cohen Anthony Victor D'Amico James A Eastham Charles A Enke Thomas A Farrington Celestia S Higano Eric Mark Horwitz Christopher J Kane Mark H Kawachi Michael Kuettel Timothy M Kuzel Richard J Lee Arnold W Malcolm David Miller Elizabeth R Plimack Julio M Pow-Sang David Raben Sylvia Richey Mack Roach Eric Rohren Stan Rosenfeld Edward Schaeffer Eric J Small Guru Sonpavde Sandy Srinivas Cy Stein Seth A Strope Jonathan Tward Dorothy A Shead Maria Ho

J Natl Compr Canc Netw 2014 May;12(5):686-718

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http://dx.doi.org/10.6004/jnccn.2014.0072DOI Listing
May 2014

Neuroendocrine prostate cancer: subtypes, biology, and clinical outcomes.

Authors:
Rahul Aggarwal Tian Zhang Eric J Small Andrew J Armstrong

J Natl Compr Canc Netw 2014 May;12(5):719-26

From the aDepartment of Medicine, Division of Hematology/Oncology, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, and Department of Medicine, and bDepartment of Medicine, Division of Medical Oncology, Duke Cancer Institute, Durham, North Carolina.

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http://dx.doi.org/10.6004/jnccn.2014.0073DOI Listing
May 2014

Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance).

Authors:
Matthew R Smith Susan Halabi Charles J Ryan Arif Hussain Nicholas Vogelzang Walter Stadler Ralph J Hauke J Paul Monk Philip Saylor Nirmala Bhoopalam Fred Saad Ben Sanford W Kevin Kelly Michael Morris Eric J Small

J Clin Oncol 2014 Apr 3;32(11):1143-50. Epub 2014 Mar 3.

Matthew R. Smith and Philip Saylor, Massachusetts General Hospital Cancer Center, Boston, MA; Susan Halabi and Ben Sanford, Alliance Statistics and Data Center, Duke University Medical Center, Durham, NC; Charles J. Ryan and Eric J. Small, University of California at San Francisco, San Francisco, CA; Walter Stadler, University of Chicago; Nirmala Bhoopalam, Loyola University of Chicago, Chicago, IL; Arif Hussain, University of Maryland, Baltimore, MD; Nicholas Vogelzang, Nevada Cancer Research Foundation CCOP, Las Vegas, NV; Ralph J. Hauke, University of Nebraska, Omaha, NE; J. Paul Monk, Ohio State University, Columbus, OH; W. Kevin Kelly, Thomas Jefferson University, Philadelphia, PA; Michael Morris, Memorial Sloan-Kettering Cancer Center, New York, NY; Fred Saad, Centre Hospitalier de l'Université de Montréal, Montreal, Canada.

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http://dx.doi.org/10.1200/JCO.2013.51.6500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970172PMC
April 2014

Updated prognostic model for predicting overall survival in first-line chemotherapy for patients with metastatic castration-resistant prostate cancer.

Authors:
Susan Halabi Chen-Yen Lin W Kevin Kelly Karim S Fizazi Judd W Moul Ellen B Kaplan Michael J Morris Eric J Small

J Clin Oncol 2014 Mar 21;32(7):671-7. Epub 2014 Jan 21.

Susan Halabi, Chen-Yen Lin, and Ellen B. Kaplan, Duke University; Judd W. Moul, Duke Cancer Institute, Durham, NC; W. Kevin Kelly, Thomas Jefferson University, Philadelphia, PA; Karim S. Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif, France; Michael J. Morris, Memorial Sloan-Kettering Cancer Center, New York, NY; and Eric J. Small, University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2013.52.3696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927736PMC
March 2014

Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic renal cell carcinoma.

Authors:
Susan Halabi Brian Rini Bernard Escudier Walter M Stadler Eric J Small

Cancer 2014 Jan 8;120(1):52-60. Epub 2013 Oct 8.

Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina; Alliance Statistical and Data Center, Duke University, Durham, North Carolina.

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http://doi.wiley.com/10.1002/cncr.28221
Publisher Site
http://dx.doi.org/10.1002/cncr.28221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869105PMC
January 2014

Prostate cancer, version 1.2014.

Authors:
James L Mohler Philip W Kantoff Andrew J Armstrong Robert R Bahnson Michael Cohen Anthony Victor D'Amico James A Eastham Charles A Enke Thomas A Farrington Celestia S Higano Eric Mark Horwitz Mark H Kawachi Michael Kuettel Richard J Lee Gary R Macvicar Arnold W Malcolm David Miller Elizabeth R Plimack Julio M Pow-Sang Sylvia Richey Mack Roach Eric Rohren Stan Rosenfeld Eric J Small Sandy Srinivas Cy Stein Seth A Strope Jonathan Tward Patrick C Walsh Dorothy A Shead Maria Ho

J Natl Compr Canc Netw 2013 Dec;11(12):1471-9

From 1Roswell Park Cancer Institute; 2Dana-Farber/Brigham and Women's Cancer Center; 3Duke Cancer Institute; 4The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; 5Huntsman Cancer Institute at the University of Utah; 6Memorial Sloan-Kettering Cancer Center; 7Fred & Pamela Buffett Cancer Center at The Nebraska Medical Center; 8Prostate Health Education Network; 9University of Washington/Seattle Cancer Care Alliance; 10Fox Chase Cancer Center; 11City of Hope Comprehensive Cancer Center; 12Massachusetts General Hospital Cancer Center; 13Robert H. Lurie Comprehensive Cancer Center of Northwestern University; 14Vanderbilt-Ingram Cancer Center; 15University of Michigan Comprehensive Cancer Center; 16Moffitt Cancer Center; 17St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; 18UCSF Helen Diller Family Comprehensive Cancer Center; 19The University of Texas MD Anderson Cancer Center; 20Patient Advocate; 21Stanford Cancer Institute; 22Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; 23The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; and 24National Comprehensive Cancer Network.

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http://dx.doi.org/10.6004/jnccn.2013.0174DOI Listing
December 2013