Eric J Gowans

Eric J Gowans

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Eric J Gowans

Eric J Gowans

Publications by authors named "Eric J Gowans"

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Cytolytic Perforin as an Adjuvant to Enhance the Immunogenicity of DNA Vaccines.

Vaccines (Basel) 2019 Apr 30;7(2). Epub 2019 Apr 30.

Virology Laboratory, Discipline of Surgery, Basil Hetzel Institute for Translational Health Research and University of Adelaide, Adelaide 5011, Australia.

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http://dx.doi.org/10.3390/vaccines7020038DOI Listing
April 2019

Antibody Responses to a Quadrivalent Hepatitis C Viral-Like Particle Vaccine Adjuvanted with Toll-Like Receptor 2 Agonists.

Viral Immunol 2018 05 28;31(4):338-343. Epub 2018 Feb 28.

1 Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne , Melbourne, Australia .

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http://dx.doi.org/10.1089/vim.2017.0182DOI Listing
May 2018

Preclinical Development and Production of Virus-Like Particles As Vaccine Candidates for Hepatitis C.

Front Microbiol 2017 5;8:2413. Epub 2017 Dec 5.

Virology Laboratory, Basil Hetzel Institute for Translational Medicine, Discipline of Surgery, University of Adelaide, Adelaide, SA, Australia.

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http://dx.doi.org/10.3389/fmicb.2017.02413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723323PMC
December 2017

Emerging Targets for Developing T Cell-Mediated Vaccines for Human Immunodeficiency Virus (HIV)-1.

Front Microbiol 2017 25;8:2091. Epub 2017 Oct 25.

Virology Laboratory, Basil Hetzel Institute for Translational Medicine, Discipline of Surgery, University of Adelaide, Adelaide, SA, Australia.

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http://dx.doi.org/10.3389/fmicb.2017.02091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660999PMC
October 2017

Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner.

Sci Rep 2017 08 17;7(1):8530. Epub 2017 Aug 17.

Virology Laboratory, The Basil Hetzel Institute for Translational Health Research, The University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1038/s41598-017-08063-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561019PMC
August 2017

Mucosal vaccination with a live recombinant rhinovirus followed by intradermal DNA administration elicits potent and protective HIV-specific immune responses.

Sci Rep 2016 11 17;6:36658. Epub 2016 Nov 17.

Virology Laboratory, Basil Hetzel Institute, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1038/srep36658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113119PMC
November 2016

A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice.

Sci Rep 2016 06 30;6:29131. Epub 2016 Jun 30.

Virology Laboratory, Basil Hetzel Institute, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.

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http://www.nature.com/articles/srep29131
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http://dx.doi.org/10.1038/srep29131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928126PMC
June 2016

Encoded novel forms of HSP70 or a cytolytic protein increase DNA vaccine potency.

Hum Vaccin Immunother 2014 19;10(9):2679-83. Epub 2014 Nov 19.

a Discipline of Surgery ; the University of Adelaide; Basil Hetzel Institute ; Adelaide , SA Australia.

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http://dx.doi.org/10.4161/hv.29527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975063PMC
May 2016

A Multiantigenic DNA Vaccine That Induces Broad Hepatitis C Virus-Specific T-Cell Responses in Mice.

J Virol 2015 Aug 27;89(15):7991-8002. Epub 2015 May 27.

Virology Laboratory, Discipline of Surgery, University of Adelaide and Basil Hetzel Institute for Translational Medicine, Adelaide, South Australia, Australia

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http://dx.doi.org/10.1128/JVI.00803-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505674PMC
August 2015

Immunocompetent mouse models to evaluate intrahepatic T cell responses to HCV vaccines.

Hum Vaccin Immunother 2014 ;10(12):3576-8

a Discipline of Surgery ; University of Adelaide; Basil Hetzel Institute ; Adelaide , SA , Australia.

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http://dx.doi.org/10.4161/hv.34343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514132PMC
May 2015

Engineering human rhinovirus serotype-A1 as a vaccine vector.

Virus Res 2015 May 11;203:72-6. Epub 2015 Apr 11.

Virology Laboratory, Basil Hetzel Institute, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2015.04.002DOI Listing
May 2015

Loss of long term protection with the inclusion of HIV pol to a DNA vaccine encoding gag.

Virus Res 2014 Nov 23;192:25-33. Epub 2014 Aug 23.

Virology Laboratory, Basil Hetzel Institute, Department of Surgery, University of Adelaide, Adelaide, Australia.

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http://dx.doi.org/10.1016/j.virusres.2014.08.008DOI Listing
November 2014

DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency.

Eur J Immunol 2014 Jul 11;44(7):1992-2002. Epub 2014 May 11.

Department of Surgery, Virology Laboratory, Basil Hetzel Institute, University of Adelaide, Adelaide, Australia.

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http://dx.doi.org/10.1002/eji.201343983DOI Listing
July 2014

A summary of the 20th International Symposium on Hepatitis C Virus and Related Viruses.

Gastroenterology 2014 Jul 23;147(1):e1-4. Epub 2014 May 23.

Centre for Biomedicine, Burnet Institute, Melbourne, Australia; Department of Microbiology and Immunology, University of Melbourne, Parkville, Australia; Department of Microbiology, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1053/j.gastro.2014.05.022DOI Listing
July 2014

A novel challenge model to evaluate the efficacy of hepatitis C virus vaccines in mice.

Vaccine 2014 Jun 16;32(27):3409-16. Epub 2014 Apr 16.

Virology Laboratory, Discipline of Surgery, University of Adelaide, Basil Hetzel Institute for Translational Medicine, Adelaide, SA 5011, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2014.04.014DOI Listing
June 2014

Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein.

Clin Transl Immunology 2014 Jun 27;3(6):e18. Epub 2014 Jun 27.

Discipline of Surgery, The University of Adelaide, Basil Hetzel Institute , Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1038/cti.2014.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232068PMC
June 2014

Induction of antigen-positive cell death by the expression of perforin, but not DTa, from a DNA vaccine enhances the immune response.

Immunol Cell Biol 2014 Apr 10;92(4):359-67. Epub 2013 Dec 10.

Virology Laboratory, Discipline of Surgery, University of Adelaide, Basil Hetzel Institute for Translational Medicine, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1038/icb.2013.93DOI Listing
April 2014

Hepatitis C virus nonstructural protein 5B is involved in virus morphogenesis.

J Virol 2012 May 15;86(9):5080-8. Epub 2012 Feb 15.

The Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1128/JVI.07089-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347352PMC
May 2012

The dengue virus M protein localises to the endoplasmic reticulum and forms oligomers.

FEBS Lett 2012 Apr 8;586(7):1032-7. Epub 2012 Mar 8.

Burnet Institute, 85 Commercial Road, Prahran, Victoria 3004, Australia.

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http://dx.doi.org/10.1016/j.febslet.2012.02.047DOI Listing
April 2012

Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes.

Virology 2011 Mar 22;412(1):83-90. Epub 2011 Jan 22.

Burnet Institute, 85 Commercial Road, Melbourne, Vic. 3004, Australia.

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http://dx.doi.org/10.1016/j.virol.2010.12.050DOI Listing
March 2011

Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors.

Arch Virol 2009 26;154(7):1129-38. Epub 2009 Jun 26.

The Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/s00705-009-0423-8DOI Listing
July 2009

A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection.

Vaccine 2008 Sep 7;26(37):4866-75. Epub 2008 Apr 7.

Department of Microbiology and Immunology, The University of Melbourne, Royal Parade, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.vaccine.2008.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526279PMC
September 2008

Virus-specific T-cell immunity correlates with control of GB virus B infection in marmosets.

J Virol 2008 Mar 19;82(6):3054-60. Epub 2007 Dec 19.

The Burnet Institute, G.P.O. Box 2284, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1128/JVI.01153-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259009PMC
March 2008

Natural regulatory T cells and persistent viral infection.

J Virol 2008 Jan 12;82(1):21-30. Epub 2007 Sep 12.

HCV Laboratory, Macfarlane Burnet Institute, GPO Box 2284, Melbourne, VIC 3001, Australia.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01768-07
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http://dx.doi.org/10.1128/JVI.01768-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224364PMC
January 2008

Defining target antigens for CD25+ FOXP3 + IFN-gamma- regulatory T cells in chronic hepatitis C virus infection.

Immunol Cell Biol 2007 Apr-May;85(3):197-204. Epub 2007 Jan 2.

Macfarlane Burnet Institute, Melbourne, Victoria, Australia.

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http://doi.wiley.com/10.1038/sj.icb.7100020
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http://dx.doi.org/10.1038/sj.icb.7100020DOI Listing
November 2007

Long-term storage of DNA-free RNA for use in vaccine studies.

Biotechniques 2007 Nov;43(5):675-81

Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526277PMC
http://dx.doi.org/10.2144/000112593DOI Listing
November 2007

Amantadine inhibits the function of an ion channel encoded by GB virus B, but fails to inhibit virus replication.

Antivir Ther 2006 ;11(3):289-95

John Curtin School of Medical Research, Australian National University, Canberra ACT, Australia.

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July 2006

Prospects for dendritic cell vaccination in persistent infection with hepatitis C virus.

J Clin Virol 2004 Aug;30(4):283-90

Macfarlane Burnet Institute for Medical Research and Public Health, GPO Box 2284, Melbourne, VIC 3001, Australia.

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http://dx.doi.org/10.1016/j.jcv.2004.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526278PMC
August 2004

Neutralising antibody, CTL and dendritic cell responses to hepatitis C virus: a preventative vaccine strategy.

Curr Drug Targets 2004 Jan;5(1):41-56

Department of Medicine (RMH/WH), University of Melbourne, Centre for Medical Research, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.

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January 2004

Immunogenicity of recombinant HBsAg/HCV particles in mice pre-immunised with hepatitis B virus-specific vaccine.

Vaccine 2003 Jun;21(21-22):2692-7

Sir Albert Sakzewski Virus Research Centre, Royal Children's Hospital, Herston, QLD 4029, Australia.

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June 2003

Immune responses in hepatitis C virus infection: the role of dendritic cells.

Immunol Cell Biol 2003 Feb;81(1):63-6

Macfarlane Burnet Institute for Medical Research and Public Health, Prahran, Victoria, Australia.

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http://dx.doi.org/10.1046/j.0818-9641.2002.01138.xDOI Listing
February 2003

Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus.

Immunol Cell Biol 2003 Feb;81(1):67-72

Cooperative Research Centre for Vaccine Technology, Department of Microbiology and Immunology, The University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1046/j.1440-1711.2003.01133.xDOI Listing
February 2003

Generation of CTL responses using Kunjin replicon RNA.

Immunol Cell Biol 2003 Feb;81(1):73-8

Clinical Medical Virology Centre, The University of Queensland, St Lucia and Sir Albert Sakzewski Virus Research Centre, Royal Children's Hospital, Herston, Queensland, Australia.

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http://dx.doi.org/10.1046/j.0818-9641.2002.01137.xDOI Listing
February 2003

Vitamin B12 stalls the 80 S ribosomal complex on the hepatitis C internal ribosome entry site.

J Mol Biol 2002 May;319(1):1-8

Sir Albert Sakzewski Virus Research Centre, Royal Children's Hospital, Herston, Qld 4029, Australia.

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http://dx.doi.org/10.1016/S0022-2836(02)00300-5DOI Listing
May 2002