Eric J Enemark

Eric J Enemark

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Eric J Enemark

Eric J Enemark

Publications by authors named "Eric J Enemark"

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DNA translocation mechanism of the MCM complex and implications for replication initiation.

Nat Commun 2019 Jul 15;10(1):3117. Epub 2019 Jul 15.

Department of Structural Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 311, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41467-019-11074-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629641PMC
July 2019

Fundamental Characteristics of AAA+ Protein Family Structure and Function.

Archaea 2016 14;2016:9294307. Epub 2016 Sep 14.

Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1155/2016/9294307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039278PMC
July 2017

Structure of a double hexamer of the Pyrococcus furiosus minichromosome maintenance protein N-terminal domain.

Acta Crystallogr F Struct Biol Commun 2016 07 22;72(Pt 7):545-51. Epub 2016 Jun 22.

Department of Structural Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1107/S2053230X1600858XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933004PMC
July 2016

Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and Function.

Archaea 2015 11;2015:305497. Epub 2015 Oct 11.

Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1155/2015/305497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619765PMC
November 2015

MCM ring hexamerization is a prerequisite for DNA-binding.

Nucleic Acids Res 2015 Oct 13;43(19):9553-63. Epub 2015 Sep 13.

Department of Structural Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 311, Memphis, TN 38105, USA

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http://dx.doi.org/10.1093/nar/gkv914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627082PMC
October 2015

Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis.

J Mol Biol 2015 May 25;427(9):1779-1796. Epub 2015 Feb 25.

Department of Structural Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 311, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.jmb.2015.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402148PMC
May 2015

Analysis of the crystal structure of an active MCM hexamer.

Elife 2014 Sep 29;3:e03433. Epub 2014 Sep 29.

Department of Structural Biology, St Jude Children's Research Hospital, Memphis, United States.

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http://publishing-cdn.elifesciences.org/03433/elife-03433-v1
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http://elifesciences.org/lookup/doi/10.7554/eLife.03433
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http://dx.doi.org/10.7554/eLife.03433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359371PMC
September 2014

A conserved MCM single-stranded DNA binding element is essential for replication initiation.

Elife 2014 Apr 1;3:e01993. Epub 2014 Apr 1.

Department of Structural Biology, St Jude Children's Research Hospital, Memphis, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970758PMC
http://dx.doi.org/10.7554/eLife.01993DOI Listing
April 2014

Dynamic look at DNA unwinding by a replicative helicase.

Proc Natl Acad Sci U S A 2014 Mar 18;111(9):E827-35. Epub 2014 Feb 18.

W. M. Keck Structural Biology Laboratory, Howard Hughes Medical Institute, and Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.

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http://dx.doi.org/10.1073/pnas.1322254111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948270PMC
March 2014

Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia.

Clin Cancer Res 2013 Oct 22;19(20):5758-68. Epub 2013 Aug 22.

Authors' Affiliations: Departments of Pharmaceutical Sciences, Structural Biology, Pathology, and Oncology, Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital; and Department of Pediatrics, University of Tennessee, Memphis, Tennessee.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878304PMC
October 2013

On helicases and other motor proteins.

Curr Opin Struct Biol 2008 Apr 10;18(2):243-57. Epub 2008 Mar 10.

W.M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, United States.

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http://dx.doi.org/10.1016/j.sbi.2008.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396192PMC
April 2008

Mechanism of DNA translocation in a replicative hexameric helicase.

Nature 2006 Jul;442(7100):270-5

W. M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

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http://dx.doi.org/10.1038/nature04943DOI Listing
July 2006

Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum.

Cell 2005 Jul;122(2):183-93

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

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http://dx.doi.org/10.1016/j.cell.2005.05.033DOI Listing
July 2005

Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.

EMBO J 2002 Mar;21(6):1487-96

W.M.Keck Structural Biology Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1093/emboj/21.6.1487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125917PMC
March 2002

Stereospecificity and Self-Selectivity in the Generation of a Chiral Molecular Tetrahedron by Metal-Assisted Self-Assembly.

Angew Chem Int Ed Engl 1998 Apr;37(7):932-935

Department of Chemistry, Stanford University, Stanford, CA 94305-5080 (USA), Fax: (+1) 650-725-0259.

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http://dx.doi.org/10.1002/(SICI)1521-3773(19980420)37:7<932::AID-ANIE932>3.0.CO;2-CDOI Listing
April 1998

Ligand Self-Recognition in the Self-Assembly of a [{Cu(L)} ] Complex: The Role of Chirality.

Angew Chem Int Ed Engl 1998 Apr;37(7):928-932

Department of Chemistry, Stanford University, Stanford, CA 94305-5080 (USA), Fax: (+1) 650-725-0259.

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http://dx.doi.org/10.1002/(SICI)1521-3773(19980420)37:7<928::AID-ANIE928>3.0.CO;2-TDOI Listing
April 1998