Eric Delabesse

Eric Delabesse

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Eric Delabesse

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More than ten percent of relapses occur after five years in AML patients with mutation.

Leuk Lymphoma 2020 Feb 5:1-4. Epub 2020 Feb 5.

Service d'Hématologie, Institut Universitaire du Cancer de Toulouse-Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1080/10428194.2019.1706733DOI Listing
February 2020

Outcome of patients aged 60-75 years with newly diagnosed secondary acute myeloid leukemia: A single-institution experience.

Cancer Med 2019 Jul 7;8(8):3846-3854. Epub 2019 Jun 7.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1002/cam4.2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639188PMC
July 2019

Outcome of AML patients with IDH2 mutations in real world before the era of IDH2 inhibitors.

Leuk Res 2019 Jun 27;81:82-87. Epub 2019 Apr 27.

Université Toulouse III Paul Sabatier, Toulouse, France; Cancer Research Center of Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.04.010DOI Listing
June 2019

The impact of chronic myeloid leukemia on employment: the French prospective study.

Ann Hematol 2019 Mar 17;98(3):615-623. Epub 2018 Nov 17.

Department of Occupational Diseases, Toulouse University Hospital, Bâtiment Turiaf, Place du Dr Baylac, 31059, Toulouse Cedex 9, France.

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http://link.springer.com/10.1007/s00277-018-3549-5
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http://dx.doi.org/10.1007/s00277-018-3549-5DOI Listing
March 2019

Hydroxyurea prior to intensive chemotherapy in AML with moderate leukocytosis.

Leuk Res 2018 12 31;75:7-10. Epub 2018 Oct 31.

Service d'Hématologie, CHU de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France; Université Toulouse III Paul Sabatier, Toulouse, France; Cancer Research Center of Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01452126183045
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http://dx.doi.org/10.1016/j.leukres.2018.10.015DOI Listing
December 2018

A case of B-cell precursor acute lymphoblastic leukemia with IL3-IGH rearrangement revealed by thromboembolism and marked eosinophilia.

Leuk Lymphoma 2018 10 9;59(10):2489-2492. Epub 2018 Feb 9.

c Service d'Hématologie Clinique , Grand Hôpital de l'Est Francilien , Meaux , France.

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http://dx.doi.org/10.1080/10428194.2018.1430796DOI Listing
October 2018

PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.

Proc Natl Acad Sci U S A 2018 10 26;115(41):10357-10362. Epub 2018 Sep 26.

Centre de Recherches en Cancérologie de Toulouse (CRCT), Université de Toulouse, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Toulouse III Paul Sabatier (UPS), 31037 Toulouse, France;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1721678115
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http://dx.doi.org/10.1073/pnas.1721678115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187160PMC
October 2018

Improved Survival by Adding Lomustine to Conventional Chemotherapy for Elderly Patients With AML Without Unfavorable Cytogenetics: Results of the LAM-SA 2007 FILO Trial.

J Clin Oncol 2018 Sep 27:JCO2018787366. Epub 2018 Sep 27.

Arnaud Pigneux and Pierre-Yves Dumas, Bordeaux University Hospital, Bordeaux University, INSERM 1035; Louis-Rachid Salmi, Ariane Mineur, and Julien Asselineau, Bordeaux University Hospital, Bordeaux; Marie C. Béné, and Jacques Delaunay, Nantes University Hospital, Nantes; Caroline Bonmati, Nancy University Hospital, Nancy; Romain Guièze, Clermont-Ferrand University Hospital, Clermont Ferrand; Isabelle Luquet, Eric Delabesse, and Christian Récher, Toulouse University Hospital, Toulouse; Pascale Cornillet-Lefebvre, Reims University Hospital, Reims; Jean-Christophe Ianotto, Brest University Hospital, Brest; Mario Ojeda-Uribe, Mulhouse Regional Hospital, Mulhouse; Mathilde Hunault and Norbert Ifrah, Angers University Hospital and INSERM U 892/CNRS 6299, Angers; Anne Banos, Cote Basque General Hospital, Bayonne; Luc Matthieu Fornecker, Strasbourg University Hospital, Strasbourg; Marc Bernard, Rennes University Hospital, Rennes; Eric Jourdan, Nîmes University Hospital, Nîmes; Norbert Vey, Institut Paoli Calmettes, Marseilles; Hacene Zerazhi, Avignon General Hospital, Avignon; Yosr Hishri, Montpellier University Hospital, Montpellier; Roselyne Delepine, Tours University Hospital, Tours; and Jean-Yves Cahn, Grenoble University Hospital, Grenoble, France.

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http://dx.doi.org/10.1200/JCO.2018.78.7366DOI Listing
September 2018

Intensified Therapy of Acute Lymphoblastic Leukemia in Adults: Report of the Randomized GRAALL-2005 Clinical Trial.

J Clin Oncol 2018 08 4;36(24):2514-2523. Epub 2018 Jun 4.

Françoise Huguet, Eric Delabesse, Institut Universitaire du Cancer, Toulouse; Sylvie Chevret, Nicolas Boissel, Hervé Dombret, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP); Université Paris Diderot; Agnès Buzyn, Vahid Asnafi, Elizabeth Macintyre, Hôpital Necker, AP-HP; Université Paris Descartes, Paris; Thibaut Leguay, Centre Hospitalier Universitaire, Pessac; Xavier Thomas, Véronique Lhéritier, Hôpital Lyon-Sud, Pierre Bénite; Martine Escoffre-Barbe, Centre Hospitalier Universitaire, Rennes; Patrice Chevallier, Marie C. Béné, Centre Hospitalier Universitaire, Nantes; Mathilde Hunault, Norbert Ifrah, Centre Hospitalier Universitaire, Angers; Norbert Vey, Institut Paoli-Calmettes, Marseille; Caroline Bonmati, Centre Hospitalier Universitaire, Nancy; Stéphane Lepretre, Centre Henri Becquerel, Rouen; Jean-Pierre Marolleau, Centre Hospitalier Universitaire, Amiens; Philippe Rousselot, Centre Hospitalier, Versailles; Jean-Yves Cahn, Centre Hospitalier Universitaire Grenoble-Alpes, La Tronche, France; Thomas Pabst, Inselspital; Swiss Group for Clinical Cancer Research, Bern; and Yves Chalandon, Swiss Group for Clinical Cancer Research, Bern; Hôpital Universitaire, Geneva, Switzerland.

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http://dx.doi.org/10.1200/JCO.2017.76.8192DOI Listing
August 2018

and isoforms are both efficient to drive B cell differentiation.

Oncotarget 2018 Aug 28;9(67):32841-32854. Epub 2018 Aug 28.

Inserm, UMR1037 CRCT, F-31000, Université Toulouse III-Paul Sabatier, UMR1037 CRCT, Oncopole, F-31000 Toulouse, France.

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http://dx.doi.org/10.18632/oncotarget.26003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132355PMC
August 2018

Major prognostic value of complex karyotype in addition to TP53 and IGHV mutational status in first-line chronic lymphocytic leukemia.

Hematol Oncol 2017 Dec 28;35(4):664-670. Epub 2016 Sep 28.

Service d'Hématologie Clinique, CHU de Toulouse, Institut Universitaire du Cancer Toulouse-Oncopole, Toulouse, France.

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https://www.researchgate.net/profile/Yannick_Le_Bris/publica
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http://dx.doi.org/10.1002/hon.2349DOI Listing
December 2017

Improved outcome for AML patients over the years 2000-2014.

Blood Cancer J 2017 11 29;7(12):635. Epub 2017 Nov 29.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1038/s41408-017-0011-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802565PMC
November 2017

Platelet transfusion refractoriness in patients with acute myeloid leukemia treated by intensive chemotherapy.

Leuk Res 2017 10 30;61:62-67. Epub 2017 Aug 30.

Université Toulouse III Paul Sabatier, Toulouse, France; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France; Centre de Recherches en Cancérologie de Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France.

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http://dx.doi.org/10.1016/j.leukres.2017.08.015DOI Listing
October 2017

Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia.

Blood Adv 2017 Sep 8;1(20):1760-1772. Epub 2017 Sep 8.

Laboratoire de Recherche sur les Cellules Souches Hématopoïétiques et Leucémiques, Equipe Labellisée Ligue Nationale contre le Cancer, Institut de Radiobiologie Cellulaire et Moléculaire, Commissariat à l'énergie Atomique et aux Energies Alternatives (CEA), Fontenay-aux-Roses, France.

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http://dx.doi.org/10.1182/bloodadvances.2017004960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728329PMC
September 2017

CHK1 as a therapeutic target to bypass chemoresistance in AML.

Sci Signal 2016 09 13;9(445):ra90. Epub 2016 Sep 13.

Equipe Labellisée, La Ligue Contre Le Cancer, Toulouse, France. Laboratoire d'Excellence Toulouse Cancer Labex TOUCAN, Cancer Research Center of Toulouse, Inserm U1037, CNRS ERL5294, Toulouse, France. Université Paul Sabatier, Toulouse, France.

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http://dx.doi.org/10.1126/scisignal.aac9704DOI Listing
September 2016

Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells.

Blood 2016 Feb 18;127(7):882-92. Epub 2015 Aug 18.

Cancer Research Center of Toulouse, Unité Mixte de Recherche (UMR)1037 INSERM, ERL5294 Centre National de la Recherche Scientifique (CNRS), Toulouse, France; Université Toulouse III Paul Sabatier, Toulouse, France; Université Paris Descartes, Faculté de Médecine Sorbonne Paris Cité, Paris, France.

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http://www.bloodjournal.org/content/bloodjournal/early/2015/
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http://www.bloodjournal.org/content/bloodjournal/127/7/882.f
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2015-05-64
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http://dx.doi.org/10.1182/blood-2015-05-646497DOI Listing
February 2016

Impact of obesity in favorable-risk AML patients receiving intensive chemotherapy.

Am J Hematol 2016 Feb 26;91(2):193-8. Epub 2015 Nov 26.

Service d'hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1002/ajh.24228DOI Listing
February 2016

Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations.

Mol Cancer Ther 2015 Oct 23;14(10):2364-73. Epub 2015 Jul 23.

Cancer Research Center of Toulouse (CRCT), UMR1037 INSERM, ERL5294 CNRS, Toulouse, France. Université Toulouse III Paul Sabatier, Toulouse, France. Service d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0163DOI Listing
October 2015

Comparison of 60 or 90 mg/m(2) of daunorubicin in induction therapy for acute myeloid leukemia with intermediate or unfavorable cytogenetics.

Am J Hematol 2015 Feb 19;90(2):E29-30. Epub 2014 Nov 19.

Hematology Department, Institut Paoli Calmettes, Marseille, France; Aix-Marseille University, Medecine Faculty, Marseille, France.

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http://dx.doi.org/10.1002/ajh.23884DOI Listing
February 2015

Sorafenib plus all-trans retinoic acid for AML patients with FLT3-ITD and NPM1 mutations.

Eur J Haematol 2014 Dec 18;93(6):533-6. Epub 2014 Apr 18.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Hôpital Purpan, Toulouse, France.

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http://dx.doi.org/10.1111/ejh.12334DOI Listing
December 2014

Intensive chemotherapy, azacitidine, or supportive care in older acute myeloid leukemia patients: an analysis from a regional healthcare network.

Am J Hematol 2014 Dec 20;89(12):E244-52. Epub 2014 Oct 20.

Département d'Hématologie-Médecine Interne, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France; Service d'Hématologie, Hôpitaux Universitaires de Strasbourg, F-67098, Strasbourg, France.

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http://dx.doi.org/10.1002/ajh.23848DOI Listing
December 2014

Primary leptomeningeal ALK+ lymphoma in a 13-year-old child.

J Pediatr Hematol Oncol 2008 Dec;30(12):963-7

CHU Clermont-Ferrand, Centre Régional de Cancérologie et Thérapie Cellulaire Pédiatrique, Hôtel-Dieu, France.

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http://dx.doi.org/10.1097/MPH.0b013e31818a959aDOI Listing
December 2008

Primary cutaneous Epstein-Barr virus-related lymphoproliferative disorders in 4 immunosuppressed children.

J Am Acad Dermatol 2008 Jan 19;58(1):74-80. Epub 2007 Sep 19.

Department of Pathology, Groupe Hospitalier Necker Enfants-Malades, Assistance Publique-Hôpitaux de Paris, Université Paris-Descartes, Paris, France.

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http://dx.doi.org/10.1016/j.jaad.2007.08.013DOI Listing
January 2008

A multicenter evaluation of comprehensive analysis of MLL translocations and fusion gene partners in acute leukemia using the MLL FusionChip device.

Cancer Genet Cytogenet 2007 Feb;173(1):17-22

Leukaemia Research Cytogenetics Group, Cancer Sciences Division, University of Southampton, MP 822 Duthie Building, Southampton General Hospital, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1016/j.cancergencyto.2006.09.006DOI Listing
February 2007

Expression of T-lineage-affiliated transcripts and TCR rearrangements in acute promyelocytic leukemia: implications for the cellular target of t(15;17).

Blood 2006 Nov 20;108(10):3484-93. Epub 2006 Jul 20.

Department of Hematology, Université Paris-Descartes, Faculté de Médecine, and Institut National de la Santé et de la Recherche Médicale (INSERM) EMI0210, Assistance Publique-Hôpitaux de Paris (AP-HP) Necker-Enfants Malades, Paris, France.

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http://dx.doi.org/10.1182/blood-2005-09-009977DOI Listing
November 2006

AF4p12, a human homologue to the furry gene of Drosophila, as a novel MLL fusion partner.

Cancer Res 2005 Aug;65(15):6521-5

Laboratoire d'Hématologie et de Cytogénétique, Centre Hospitalier Lyon Sud and EA 3737, Pierre-Benite, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1325DOI Listing
August 2005

Mono/oligoclonal pattern of Kaposi Sarcoma-associated herpesvirus (KSHV/HHV-8) episomes in primary effusion lymphoma cells.

Int J Cancer 2005 Jul;115(4):511-8

Unité d'Epidémiologie et de Physiopathologie des Virus Oncogènes, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1002/ijc.20926DOI Listing
July 2005

Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy.

Blood 2004 Dec 30;104(13):4173-80. Epub 2004 Mar 30.

Necker-Enfants-Malades and Trousseau, Assistance Publique-Hopitaux de Paris, INSERM EMIU210 and Université Paris V, Hôpital Purpan, Toulouse, France.

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http://dx.doi.org/10.1182/blood-2003-11-3944DOI Listing
December 2004

Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tumour suppressor gene, in patients with myeloid malignancies.

Br J Haematol 2004 Dec;127(5):509-18

Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2004.05278.xDOI Listing
December 2004

FLT3 and MLL intragenic abnormalities in AML reflect a common category of genotoxic stress.

Blood 2003 Sep 5;102(6):2198-204. Epub 2003 Jun 5.

Laboratoire d'Hématologie, Tour Pasteur, Hôpital Necker, 149-161 rue de Sèvres, 75743 Paris cedex 15, France.

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http://dx.doi.org/10.1182/blood-2003-01-0162DOI Listing
September 2003

CALM-AF10 is a common fusion transcript in T-ALL and is specific to the TCRgammadelta lineage.

Blood 2003 Aug 3;102(3):1000-6. Epub 2003 Apr 3.

Laboratoire d'Hematologie, Service d'Histologie, Embryologie, et de Cytogenetic, Service d'Hematologie Clinique, Centre Hospitalier Universitaire (CHU) Necker Enfants Malades and University Paris V, France.

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http://dx.doi.org/10.1182/blood-2002-09-2913DOI Listing
August 2003

Analysis of TCR, pT alpha, and RAG-1 in T-acute lymphoblastic leukemias improves understanding of early human T-lymphoid lineage commitment.

Blood 2003 Apr 21;101(7):2693-703. Epub 2002 Nov 21.

Department of Biological and Clinical Hematology, Centre Hospitalier-Universitaire/Assistance Publique-Hopitaux de Paris (CHU/AP-HP) Necker-Enfants Malades and Université Paris V, France.

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http://dx.doi.org/10.1182/blood-2002-08-2438DOI Listing
April 2003

Absence of SCL mutations in myeloid malignancies.

Br J Haematol 2003 Feb;120(3):482-3

University of Cambridge, Department of Haematology, Cambridge Institute for Medical Research, Cambridge, UK.

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http://dx.doi.org/10.1046/j.1365-2141.2003.04122.xDOI Listing
February 2003