Publications Authored by Eric D Wieben

Recommendations for performance optimizations when using GATK3.8 and GATK4.

Authors:

Jacob R Heldenbrand Saurabh Baheti Matthew A Bockol Travis M Drucker Steven N Hart Matthew E Hudson Ravishankar K Iyer Michael T Kalmbach Katherine I Kendig Eric W Klee Nathan R Mattson Eric D Wieben Mathieu Wiepert Derek E Wildman Liudmila S Mainzer

BMC Bioinformatics 2019 Nov 8;20(1):557. Epub 2019 Nov 8.

National Center for Supercomputing Applications, University of Illinois at Urbana-Champaign, 1205 W. Clark St., Urbana, IL, USA.

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http://dx.doi.org/10.1186/s12859-019-3169-7	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842142	PMC

November 2019

Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy.

Authors:

Eric D Wieben Keith H Baratz Ross A Aleff Krishna R Kalari Xiaojia Tang Leo J Maguire Sanjay V Patel Michael P Fautsch

Invest Ophthalmol Vis Sci 2019 Aug;60(10):3636-3643

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.

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http://dx.doi.org/10.1167/iovs.19-27689	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716950	PMC

August 2019

Sentieon DNASeq Variant Calling Workflow Demonstrates Strong Computational Performance and Accuracy.

Authors:

Katherine I Kendig Saurabh Baheti Matthew A Bockol Travis M Drucker Steven N Hart Jacob R Heldenbrand Mikel Hernaez Matthew E Hudson Michael T Kalmbach Eric W Klee Nathan R Mattson Christian A Ross Morgan Taschuk Eric D Wieben Mathieu Wiepert Derek E Wildman Liudmila S Mainzer

Front Genet 2019 20;10:736. Epub 2019 Aug 20.

National Center for Supercomputing Applications, University of Illinois at Urbana-Champaign, Urbana, IL, United States.

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http://dx.doi.org/10.3389/fgene.2019.00736	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710408	PMC

August 2019

Association of rs613872 and Trinucleotide Repeat Expansion in the TCF4 Gene of German Patients With Fuchs Endothelial Corneal Dystrophy.

Authors:

Naoki Okumura Ryousuke Hayashi Masakazu Nakano Kei Tashiro Kengo Yoshii Ross Aleff Malinda Butz Edward W Highsmith Eric D Wieben Michael P Fautsch Keith H Baratz Yuya Komori Emi Ueda Makiko Nakahara Julia Weller Theofilos Tourtas Ursula Schlötzer-Schrehardt Friedrich Kruse Noriko Koizumi

Cornea 2019 Jul;38(7):799-805

Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.

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http://dx.doi.org/10.1097/ICO.0000000000001952	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554040	PMC

July 2019

Amplification-free long-read sequencing of TCF4 expanded trinucleotide repeats in Fuchs Endothelial Corneal Dystrophy.

Authors:

Eric D Wieben Ross A Aleff Shubham Basu Vivekananda Sarangi Brett Bowman Ian J McLaughlin John R Mills Malinda L Butz Edward W Highsmith Cristiane M Ida Jenny M Ekholm Keith H Baratz Michael P Fautsch

PLoS One 2019 5;14(7):e0219446. Epub 2019 Jul 5.

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219446	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611681	PMC

July 2019

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy.

Authors:

Naoki Okumura Ryosuke Hayashi Masakazu Nakano Kengo Yoshii Kei Tashiro Takahiko Sato Derek J Blake Ross Aleff Malinda Butz Edward W Highsmith Eric D Wieben Michael P Fautsch Keith H Baratz Yuya Komori Makiko Nakahara Theofilos Tourtas Ursula Schlötzer-Schrehardt Friedrich Kruse Noriko Koizumi

Invest Ophthalmol Vis Sci 2019 02;60(2):779-786

Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.

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http://dx.doi.org/10.1167/iovs.18-25760	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392475	PMC

February 2019

Gene expression in the corneal endothelium of Fuchs endothelial corneal dystrophy patients with and without expansion of a trinucleotide repeat in TCF4.

Authors:

Eric D Wieben Ross A Aleff Xiaojia Tang Krishna R Kalari Leo J Maguire Sanjay V Patel Keith H Baratz Michael P Fautsch

PLoS One 2018 2;13(7):e0200005. Epub 2018 Jul 2.

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200005	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028112	PMC

January 2019

Germline Rare Coding Variants and Risk of Pancreatic Cancer in Minority Populations.

Cancer Epidemiol Biomarkers Prev 2018 11 23;27(11):1364-1370. Epub 2018 Jul 23.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-1065	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214745	PMC

November 2018

Fuchs' Endothelial Corneal Dystrophy in Patients With Myotonic Dystrophy, Type 1.

Authors:

Nelson S Winkler Margherita Milone Jennifer M Martinez-Thompson Harish Raja Ross A Aleff Sanjay V Patel Michael P Fautsch Eric D Wieben Keith H Baratz

Invest Ophthalmol Vis Sci 2018 06;59(7):3053-3057

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.

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http://dx.doi.org/10.1167/iovs.17-23160	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005624	PMC

June 2018

Autosomal dominant calpainopathy due to heterozygous CAPN3 C.643_663del21.

Authors:

Jennifer M Martinez-Thompson Zhiyv Niu Jennifer A Tracy Steven A Moore Andrea Swenson Eric D Wieben Margherita Milone

Muscle Nerve 2018 04 30;57(4):679-683. Epub 2017 Sep 30.

Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.

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http://dx.doi.org/10.1002/mus.25970	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915624	PMC

April 2018

Utility of DNA, RNA, Protein, and Functional Approaches to Solve Cryptic Immunodeficiencies.

Authors:

Margot A Cousin Matthew J Smith Ashley N Sigafoos Jay J Jin Marine I Murphree Nicole J Boczek Patrick R Blackburn Gavin R Oliver Ross A Aleff Karl J Clark Eric D Wieben Avni Y Joshi Pavel N Pichurin Roshini S Abraham Eric W Klee

J Clin Immunol 2018 04 18;38(3):307-319. Epub 2018 Apr 18.

Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s10875-018-0499-6	DOI Listing

April 2018

Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy.

Authors:

Elisabetta Soragni Lina Petrosyan Tommy A Rinkoski Eric D Wieben Keith H Baratz Michael P Fautsch Joel M Gottesfeld

Invest Ophthalmol Vis Sci 2018 04;59(5):1888-1896

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, United States.

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http://dx.doi.org/10.1167/iovs.17-23265	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886103	PMC

April 2018

Molecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.

Authors:

Jan B Egan David L Marks Tara L Hogenson Anne M Vrabel Ashley N Sigafoos Ezequiel J Tolosa Ryan M Carr Stephanie L Safgren Elisa Enriquez Hesles Luciana L Almada Paola A Romecin-Duran Eriko Iguchi Aryan Ala'Aldeen Jean-Pierre A Kocher Gavin R Oliver Naresh Prodduturi David W Mead Asif Hossain Norine E Huneke Colleen M Tagtow Sikander Ailawadhi Stephen M Ansell Michaela S Banck Alan H Bryce Estrella M Carballido Asher A Chanan-Khan Kelly K Curtis Ernesto Resnik Chelsea D Gawryletz Ronald S Go Thorvardur R Halfdanarson Thai H Ho Richard W Joseph Prashant Kapoor Aaron S Mansfield Nathalie Meurice Amulya A Nageswara Rao Grzegorz S Nowakowski Animesh Pardanani Sameer A Parikh John C Cheville Andrew L Feldman Ramesh K Ramanathan Steven I Robinson Raoul Tibes Heidi D Finnes Jennifer B McCormick Robert R McWilliams Aminah Jatoi Mrinal M Patnaik Alvin C Silva Eric D Wieben Tammy M McAllister Kandelaria M Rumilla Sarah E Kerr Konstantinos N Lazaridis Gianrico Farrugia A Keith Stewart Karl J Clark Eileen J Kennedy Eric W Klee Mitesh J Borad Martin E Fernandez-Zapico

JCO Precis Oncol 2017 1;2017. Epub 2017 Aug 1.

David L. Marks, Tara L. Hogenson, Anne M. Vrabel, Ashley N. Sigafoos, Ezequiel J. Tolosa, Ryan M. Carr, Stephanie L. Safgren, Elisa Enriquez Hesles, Luciana L. Almada, Paola A. Romecin-Duran, Eriko Iguchi, Aryan Ala'Aldeen, Jean-Pierre A. Kocher, Gavin R. Oliver, Naresh Prodduturi, David W. Mead, Asif Hossain, Norine E. Huneke, Colleen M. Tagtow, Sikander Ailawadhi, Stephen M. Ansell, Michaela S. Banck, Asher A. Chanan-Khan, Ronald S. Go, Thorvardur R. Halfdanarson, Richard W. Joseph, Prashant Kapoor, Aaron S. Mansfield, Amulya A. Nageswara Rao, Grzegorz S. Nowakowski, Animesh Pardanani, Sameer A. Parikh, John C. Cheville, Andrew L. Feldman, Ramesh K. Ramanathan, Steven I. Robinson, Heidi D. Finnes, Jennifer B. McCormick, Robert R. McWilliams, Aminah Jatoi, Mrinal M. Patnaik, Eric D. Wieben, Tammy M. McAllister, Kandelaria M. Rumilla, Sarah E. Kerr, Konstantinos N. Lazaridis, Gianrico Farrugia, Karl J. Clark, Eric W. Klee, and Martin E. Fernandez-Zapico, Mayo Clinic, Rochester; Ernesto Resnik, Bio-Techne, Minneapolis, MN; Sikander Ailawadhi, Asher A. Chanan-Khan, and Richard W. Joseph, Mayo Clinic, Jacksonville, FL; Jan B. Egan, Alan H. Bryce, Estrella M. Carballido, KellyK. Curtis, Chelsea D. Gawryletz, Thai H. Ho,Nathalie Meurice, Ramesh K. Ramanathan, Raoul Tibes, Alvin C. Silva, A. Keith Stewart, and Mitesh J. Borad, Mayo Clinic, Phoenix, AZ; and Eileen J. Kennedy, University of Georgia, Athens, GA.

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http://dx.doi.org/10.1200/PO.17.00018	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369924	PMC

August 2017

Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance.

Clin Cancer Res 2017 Aug 4;23(16):4704-4715. Epub 2017 May 4.

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0017	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644285	PMC

August 2017

Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer.

J Natl Cancer Inst 2017 07;109(7)

Department of Surgery, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1093/jnci/djw306	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408989	PMC

July 2017

Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma.

Authors:

Xueju Wang Surendra Dasari Grzegorz S Nowakowski Konstantinos N Lazaridis Eric D Wieben Marshall E Kadin Andrew L Feldman Rebecca L Boddicker

Oncotarget 2017 Apr;8(16):26245-26255

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.18632/oncotarget.15441	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432253	PMC

April 2017

Erratum to: Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers.

Authors:

Zhifu Sun Liang Wang Bruce W Eckloff Bo Deng Yi Wang Jason A Wampfler JinSung Jang Eric D Wieben Jin Jen Ming You Ping Yang

BMC Med Genomics 2017 01 5;10(1). Epub 2017 Jan 5.

Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12	Publisher Site
http://dx.doi.org/10.1186/s12920-016-0237-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217568	PMC

January 2017

Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy.

Authors:

Eric D Wieben Ross A Aleff Xiaojia Tang Malinda L Butz Krishna R Kalari Edward W Highsmith Jin Jen George Vasmatzis Sanjay V Patel Leo J Maguire Keith H Baratz Michael P Fautsch

Invest Ophthalmol Vis Sci 2017 01;58(1):343-352

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.

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http://dx.doi.org/10.1167/iovs.16-20900	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270622	PMC

January 2017

Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy.

PLoS One 2015 22;10(12):e0145176. Epub 2015 Dec 22.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145176	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687867	PMC

June 2016

Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic: The Mayo Clinic Experience.

Mayo Clin Proc 2016 Mar;91(3):297-307

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN; Center for Individualized Medicine, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2015.12.018	DOI Listing

March 2016

Whole Exome Sequencing and Heterologous Cellular Electrophysiology Studies Elucidate a Novel Loss-of-Function Mutation in the CACNA1A-Encoded Neuronal P/Q-Type Calcium Channel in a Child With Congenital Hypotonia and Developmental Delay.

Authors:

Derek L Weyhrauch Dan Ye Nicole J Boczek David J Tester Ralitza H Gavrilova Marc C Patterson Eric D Wieben Michael J Ackerman

Pediatr Neurol 2016 Feb 6;55:46-51. Epub 2015 Nov 6.

Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota; Department of Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), Mayo Clinic, Rochester, Minnesota; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2015.10.014	DOI Listing

February 2016

Whole-Exome Sequencing of 10 Scientists: Evaluation of the Process and Outcomes.

Mayo Clin Proc 2015 Oct;90(10):1327-37

Biomedical Ethics Program, Mayo Clinic, Rochester, MN; Division of General Internal Medicine, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2015.05.021	DOI Listing

October 2015

Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy.

Breast Cancer Res Treat 2015 Sep 22;153(2):435-43. Epub 2015 Aug 22.

Center for Individualized Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s10549-015-3545-6	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559569	PMC

September 2015

Recessive MYH6 Mutations in Hypoplastic Left Heart With Reduced Ejection Fraction.

Authors:

Jeanne L Theis Michael T Zimmermann Jared M Evans Bruce W Eckloff Eric D Wieben Muhammad Y Qureshi Patrick W O'Leary Timothy M Olson

Circ Cardiovasc Genet 2015 Aug 17;8(4):564-71. Epub 2015 Jun 17.

From the Cardiovascular Genetics Research Laboratory (J.L.T., T.M.O.), Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine (M.Y.Q., P.W.O'L., T.M.O.), Division of Cardiovascular Diseases, Department of Internal Medicine (T.M.O.), Departments of Health Sciences Research and Biomedical Statistics and Informatics (M.T.Z., J.M.E.), Medical Genome Facility (B.W.E., E.D.W.), and Department of Biochemistry and Molecular Biology (E.D.W.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1161/CIRCGENETICS.115.001070	DOI Listing

August 2015

How well do whole exome sequencing results correlate with medical findings? A study of 89 Mayo Clinic Biobank samples.

Authors:

Sumit Middha Noralane M Lindor Shannon K McDonnell Janet E Olson Kiley J Johnson Eric D Wieben Gianrico Farrugia James R Cerhan Stephen N Thibodeau

Front Genet 2015 24;6:244. Epub 2015 Jul 24.

Center for Individualized Medicine, Mayo Clinic Rochester, MN, USA ; Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN, USA.

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http://dx.doi.org/10.3389/fgene.2015.00244	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513238	PMC

August 2015

Trinucleotide Repeat Expansion in the TCF4 Gene in Fuchs' Endothelial Corneal Dystrophy in Japanese.

Authors:

Masakazu Nakano Naoki Okumura Hiroko Nakagawa Noriko Koizumi Yoko Ikeda Morio Ueno Kengo Yoshii Hiroko Adachi Ross A Aleff Malinda L Butz W Edward Highsmith Kei Tashiro Eric D Wieben Shigeru Kinoshita Keith H Baratz

Invest Ophthalmol Vis Sci 2015 Jul;56(8):4865-9

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.

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http://dx.doi.org/10.1167/iovs.15-17082	DOI Listing

July 2015

RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy.

Authors:

Jintang Du Ross A Aleff Elisabetta Soragni Krishna Kalari Jinfu Nie Xiaojia Tang Jaime Davila Jean-Pierre Kocher Sanjay V Patel Joel M Gottesfeld Keith H Baratz Eric D Wieben

J Biol Chem 2015 Mar 15;290(10):5979-90. Epub 2015 Jan 15.

the Departments of Biochemistry and Molecular Biology,

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http://dx.doi.org/10.1074/jbc.M114.621607	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358235	PMC

March 2015

Case-only exome sequencing and complex disease susceptibility gene discovery: study design considerations.

Authors:

Lang Wu Daniel J Schaid Hugues Sicotte Eric D Wieben Hu Li Gloria M Petersen

J Med Genet 2015 Jan 4;52(1):10-6. Epub 2014 Nov 4.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1136/jmedgenet-2014-102697	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503357	PMC

January 2015

TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy.

Authors:

Jeanne L Theis Michael T Zimmermann Brandon T Larsen Inna N Rybakova Pamela A Long Jared M Evans Sumit Middha Mariza de Andrade Richard L Moss Eric D Wieben Virginia V Michels Timothy M Olson

Hum Mol Genet 2014 Nov 11;23(21):5793-804. Epub 2014 Jun 11.

Cardiovascular Genetics Research Laboratory, Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine,

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http://dx.doi.org/10.1093/hmg/ddu297	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189907	PMC

November 2014

Novel de novo heterozygous FGFR1 mutation in two siblings with Hartsfield syndrome: a case of gonadal mosaicism.

Authors:

Radhika Dhamija Salman Kirmani Xiangling Wang Matthew J Ferber Eric D Wieben Konstantinos N Lazaridis Dusica Babovic-Vuksanovic

Am J Med Genet A 2014 Sep 28;164A(9):2356-9. Epub 2014 May 28.

Department of Medical Genetics, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/ajmg.a.36621	DOI Listing

September 2014

Promoter-proximal transcription factor binding is transcriptionally active when coupled with nucleosome repositioning in immediate vicinity.

Authors:

Vinod Kumar Yadav Ram Krishna Thakur Bruce Eckloff Aradhita Baral Ankita Singh Rashi Halder Akinchan Kumar Mohammad Parwez Alam Tapas K Kundu Raj Pandita Tej K Pandita Eric D Wieben Shantanu Chowdhury

Nucleic Acids Res 2014 Sep 31;42(15):9602-11. Epub 2014 Jul 31.

GNR Center for Genome Informatics, Institute of Genomics and Integrative Biology, Delhi, India Proteomics and Structural Biology Unit, Institute of Genomics and Integrative Biology, Delhi, India

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http://dx.doi.org/10.1093/nar/gku596	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150765	PMC

September 2014

Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA.

Authors:

Bo Deng Julian Molina Marie C Aubry Zhifu Sun Liang Wang Bruce W Eckloff George Vasmatzis Ming You Eric D Wieben Jin Jen Dennis A Wigle Ping Yang

Cell Biosci 2014 9;4:35. Epub 2014 Jul 9.

Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1186/2045-3701-4-35	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124500	PMC

August 2014

Comprehensive assessment of genetic variants within TCF4 in Fuchs' endothelial corneal dystrophy.

Authors:

Eric D Wieben Ross A Aleff Bruce W Eckloff Elizabeth J Atkinson Saurabh Baheti Sumit Middha William L Brown Sanjay V Patel Jean-Pierre A Kocher Keith H Baratz

Invest Ophthalmol Vis Sci 2014 Aug 28;55(9):6101-7. Epub 2014 Aug 28.

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.

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http://dx.doi.org/10.1167/iovs.14-14958	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179444	PMC

August 2014

Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers.

Authors:

Zhifu Sun Liang Wang Bruce W Eckloff Bo Deng Yi Wang Jason A Wampfler JinSung Jang Eric D Wieben Jin Jen Ming You Ping Yang

BMC Med Genomics 2014 Jun 4;7:32. Epub 2014 Jun 4.

Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/1755-8794-7-32	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060138	PMC

June 2014

Genomic medicine and incidental findings: balancing actionability and patient autonomy.

Authors:

Jennifer B McCormick Richard R Sharp Gianrico Farrugia Noralane M Lindor Dusica Babovic-Vuksanovic Mitesh J Borad Alan H Bryce Richard J Caselli Matthew J Ferber Kiley J Johnson Konstantinos N Lazaridis Robert R McWilliams Joseph A Murray Alexander S Parker Kimberly A Schahl Eric D Wieben

Mayo Clin Proc 2014 Jun;89(6):718-21

Center for Individualized Medicine, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2014.04.008	DOI Listing

June 2014

Contribution of FKBP5 genetic variation to gemcitabine treatment and survival in pancreatic adenocarcinoma.

Authors:

Katarzyna A Ellsworth Bruce W Eckloff Liang Li Irene Moon Brooke L Fridley Gregory D Jenkins Erin Carlson Abra Brisbin Ryan Abo William Bamlet Gloria Petersen Eric D Wieben Liewei Wang

PLoS One 2013 1;8(8):e70216. Epub 2013 Aug 1.

Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070216	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731355	PMC

March 2014

Implementing individualized medicine into the medical practice.

Am J Med Genet C Semin Med Genet 2014 Mar 10;166C(1):15-23. Epub 2014 Mar 10.

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http://doi.wiley.com/10.1002/ajmg.c.31387	Publisher Site
http://dx.doi.org/10.1002/ajmg.c.31387	DOI Listing

March 2014

Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol.

Mayo Clin Proc 2014 Jan;89(1):25-33

Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2013.10.021	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932754	PMC

January 2014

PredictSNP: robust and accurate consensus classifier for prediction of disease-related mutations.

Authors:

Jaroslav Bendl Jan Stourac Ondrej Salanda Antonin Pavelka Eric D Wieben Jaroslav Zendulka Jan Brezovsky Jiri Damborsky

PLoS Comput Biol 2014 Jan 16;10(1):e1003440. Epub 2014 Jan 16.

Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic ; Center of Biomolecular and Cellular Engineering, International Centre for Clinical Research, St. Anne's University Hospital Brno, Brno, Czech Republic.

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http://dx.doi.org/10.1371/journal.pcbi.1003440	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894168	PMC

January 2014

Multi-platform analysis of microRNA expression measurements in RNA from fresh frozen and FFPE tissues.

Authors:

Christopher P Kolbert Rod M Feddersen Fariborz Rakhshan Diane E Grill Gyorgy Simon Sumit Middha Jin Sung Jang Vernadette Simon Debra A Schultz Michael Zschunke Wilma Lingle Jennifer M Carr E Aubrey Thompson Ann L Oberg Bruce W Eckloff Eric D Wieben Peter Li Ping Yang Jin Jen

PLoS One 2013 31;8(1):e52517. Epub 2013 Jan 31.

Medical Genome Facility Gene Expression Core, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052517	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561362	PMC

September 2013

The genomic landscape of small intestine neuroendocrine tumors.

Authors:

Michaela S Banck Rahul Kanwar Amit A Kulkarni Ganesh K Boora Franziska Metge Benjamin R Kipp Lizhi Zhang Erik C Thorland Kay T Minn Ramesh Tentu Bruce W Eckloff Eric D Wieben Yanhong Wu Julie M Cunningham David M Nagorney Judith A Gilbert Matthew M Ames Andreas S Beutler

J Clin Invest 2013 Jun 15;123(6):2502-8. Epub 2013 May 15.

Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1172/JCI67963	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668835	PMC

June 2013

A common trinucleotide repeat expansion within the transcription factor 4 (TCF4, E2-2) gene predicts Fuchs corneal dystrophy.

Authors:

Eric D Wieben Ross A Aleff Nirubol Tosakulwong Malinda L Butz W Edward Highsmith Albert O Edwards Keith H Baratz

PLoS One 2012 21;7(11):e49083. Epub 2012 Nov 21.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049083	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504061	PMC

May 2013

Natriuretic peptide receptor-3 gene (NPR3): nonsynonymous polymorphism results in significant reduction in protein expression because of accelerated degradation.

Authors:

Naveen L Pereira Dong Lin Linda Pelleymounter Irene Moon Gail Stilling Bruce W Eckloff Eric D Wieben Margaret M Redfield John C Burnett Vivien C Yee Richard M Weinshilboum

Circ Cardiovasc Genet 2013 Apr 14;6(2):201-10. Epub 2013 Mar 14.

Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.112.964742	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685298	PMC

April 2013

FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder.

Authors:

Katarzyna A Ellsworth Irene Moon Bruce W Eckloff Brooke L Fridley Gregory D Jenkins Anthony Batzler Joanna M Biernacka Ryan Abo Abra Brisbin Yuan Ji Scott Hebbring Eric D Wieben David A Mrazek Richard M Weinshilboum Liewei Wang

Pharmacogenet Genomics 2013 Mar;23(3):156-66

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835dc133	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784025	PMC

March 2013

Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation.

Authors:

Yuan Ji Kendra K S Nordgren Yubo Chai Scott J Hebbring Gregory D Jenkins Ryan P Abo Yi Peng Linda L Pelleymounter Irene Moon Bruce W Eckloff Xiaoshan Chai Jianping Zhang Brooke L Fridley Vivien C Yee Eric D Wieben Richard M Weinshilboum

Drug Metab Dispos 2012 Oct 17;40(10):1984-92. Epub 2012 Jul 17.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/dmd.112.046953	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463826	PMC

October 2012

Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.

Authors:

Scott J Hebbring Yubo Chai Yuan Ji Ryan P Abo Gregory D Jenkins Brooke Fridley Jianping Zhang Bruce W Eckloff Eric D Wieben Richard M Weinshilboum

J Neurochem 2012 Mar 6;120(6):881-90. Epub 2012 Feb 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07646.x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296836	PMC

March 2012

Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer.

Authors:

Liang Li Daniel J Schaid Brooke L Fridley Krishna R Kalari Gregory D Jenkins Ryan P Abo Anthony Batzler Irene Moon Linda Pelleymounter Bruce W Eckloff Eric D Wieben Zhifu Sun Ping Yang Liewei Wang

Pharmacogenet Genomics 2012 Feb;22(2):105-16

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://pdfs.journals.lww.com/jpharmacogenetics/2012/02000/Ge	Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land	Publisher Site
http://dx.doi.org/10.1097/FPC.0b013e32834dd7e2	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259218	PMC

February 2012

Homozygosity mapping and exome sequencing reveal GATAD1 mutation in autosomal recessive dilated cardiomyopathy.

Authors:

Jeanne L Theis Katharine M Sharpe Martha E Matsumoto High Seng Chai Asha A Nair Jason D Theis Mariza de Andrade Eric D Wieben Virginia V Michels Timothy M Olson

Circ Cardiovasc Genet 2011 Dec 30;4(6):585-94. Epub 2011 Sep 30.

Cardiovascular Genetics Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.111.961052	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248690	PMC

December 2011

Hereditary hyperferritinemia-cataract syndrome in two large multigenerational American families.

Authors:

Julia Shekunov Piet C de Groen Noralane M Lindor George G Klee Ross A Aleff Eric D Wieben Brian G Mohney

J AAPOS 2011 Aug;15(4):356-61

College of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1016/j.jaapos.2011.03.020	DOI Listing

August 2011

Prevalence of CDKN2A mutations in pancreatic cancer patients: implications for genetic counseling.

Authors:

Robert R McWilliams Eric D Wieben Kari G Rabe Katrina S Pedersen Yanhong Wu Hugues Sicotte Gloria M Petersen

Eur J Hum Genet 2011 Apr 8;19(4):472-8. Epub 2010 Dec 8.

Department of Oncology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/ejhg.2010.198	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060321	PMC

April 2011

Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing.

Authors:

Andrew L Feldman Ahmet Dogan David I Smith Mark E Law Stephen M Ansell Sarah H Johnson Julie C Porcher Nazan Ozsan Eric D Wieben Bruce W Eckloff George Vasmatzis

Blood 2011 Jan 28;117(3):915-9. Epub 2010 Oct 28.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1182/blood-2010-08-303305	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035081	PMC

January 2011

Natriuretic peptide pharmacogenetics: membrane metallo-endopeptidase (MME): common gene sequence variation, functional characterization and degradation.

Authors:

Naveen L Pereira Pinar Aksoy Irene Moon Yi Peng Margaret M Redfield John C Burnett Eric D Wieben Vivien C Yee Richard M Weinshilboum

J Mol Cell Cardiol 2010 Nov 6;49(5):864-74. Epub 2010 Aug 6.

Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2010.07.020	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092155	PMC

November 2010

Myosin individualized: single nucleotide polymorphisms in energy transduction.

Authors:

Thomas P Burghardt Kevin L Neff Eric D Wieben Katalin Ajtai

BMC Genomics 2010 Mar 15;11:172. Epub 2010 Mar 15.

Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/1471-2164-11-172	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848645	PMC

March 2010

Functional genetic polymorphisms in the aromatase gene CYP19 vary the response of breast cancer patients to neoadjuvant therapy with aromatase inhibitors.

Authors:

Liewei Wang Katarzyna A Ellsworth Irene Moon Linda L Pelleymounter Bruce W Eckloff Yvette N Martin Brooke L Fridley Gregory D Jenkins Anthony Batzler Vera J Suman Saranya Ravi J Michael Dixon William R Miller Eric D Wieben Aman Buzdar Richard M Weinshilboum James N Ingle

Cancer Res 2010 Jan;70(1):319-28

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3224	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804935	PMC

January 2010

3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer.

Authors:

Yan W Asmann Eric W Klee E Aubrey Thompson Edith A Perez Sumit Middha Ann L Oberg Terry M Therneau David I Smith Gregory A Poland Eric D Wieben Jean-Pierre A Kocher

BMC Genomics 2009 Nov 16;10:531. Epub 2009 Nov 16.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/1471-2164-10-531	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781828	PMC

November 2009

Human S-adenosylhomocysteine hydrolase: common gene sequence variation and functional genomic characterization.

Authors:

Qiping Feng Mani Keshtgarpour Linda L Pelleymounter Irene Moon Krishna R Kalari Bruce W Eckloff Eric D Wieben Richard M Weinshilboum

J Neurochem 2009 Sep 8;110(6):1806-17. Epub 2009 Jul 8.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic-Mayo Medical School, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2009.06276.x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838417	PMC

September 2009

Human glucocorticoid receptor alpha gene (NR3C1) pharmacogenomics: gene resequencing and functional genomics.

Authors:

Nifang Niu Venkatraman Manickam Krishna R Kalari Irene Moon Linda L Pelleymounter Bruce W Eckloff Eric D Wieben Daniel J Schaid Liewei Wang

J Clin Endocrinol Metab 2009 Aug 12;94(8):3072-84. Epub 2009 May 12.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.	Publisher Site
http://dx.doi.org/10.1210/jc.2008-2109	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730876	PMC

August 2009

Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics.

Authors:

Pinar Aksoy Min Jia Zhu Krishna R Kalari Irene Moon Linda L Pelleymounter Bruce W Eckloff Eric D Wieben Vivien C Yee Richard M Weinshilboum Liewei Wang

Pharmacogenet Genomics 2009 Aug;19(8):567-76

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32832c14b8	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763634	PMC

August 2009

Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry.

Authors:

Victor M Karpyak Jeong-Hyun Kim Joanna M Biernacka Eric D Wieben David A Mrazek John L Black Doo-Sup Choi

Alcohol Clin Exp Res 2009 Apr 21;33(4):712-21. Epub 2009 Jan 21.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1111/j.1530-0277.2008.00888.x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819379	PMC

April 2009

Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics.

Authors:

Neslihan Aygun Kocabas Pinar Aksoy Linda L Pelleymounter Irene Moon Jeong-Seon Ryu Judith A Gilbert Oreste Ezequel Salavaggione Bruce W Eckloff Eric D Wieben Vivien Yee Richard M Weinshilboum Matthew M Ames

Drug Metab Dispos 2008 Sep 12;36(9):1951-9. Epub 2008 Jun 12.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.108.020925	Publisher Site
http://dx.doi.org/10.1124/dmd.108.020925	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066084	PMC

September 2008

Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization.

Authors:

Fang Li Qiping Feng Candace Lee Shuzhan Wang Linda L Pelleymounter Irene Moon Bruce W Eckloff Eric D Wieben Daniel J Schaid Vivien Yee Richard M Weinshilboum

Mol Genet Metab 2008 Jul 23;94(3):326-35. Epub 2008 May 23.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.ymgme.2008.03.013	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515933	PMC

July 2008

Dok-7 myasthenia: phenotypic and molecular genetic studies in 16 patients.

Authors:

Duygu Selcen Margherita Milone Xin-Ming Shen C Michel Harper Anthony A Stans Eric D Wieben Andrew G Engel

Ann Neurol 2008 Jul;64(1):71-87

Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1002/ana.21408	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570015	PMC

July 2008

Proteasome beta subunit pharmacogenomics: gene resequencing and functional genomics.

Authors:

Liewei Wang Shaji Kumar Brooke L Fridley Krishna R Kalari Irene Moon Linda L Pelleymounter Michelle A T Hildebrandt Anthony Batzler Bruce W Eckloff Eric D Wieben Philip R Greipp

Clin Cancer Res 2008 Jun;14(11):3503-13

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-5150	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778274	PMC

June 2008

Glutathione s-transferase p1: gene sequence variation and functional genomic studies.

Authors:

Ann M Moyer Oreste E Salavaggione Tse-Yu Wu Irene Moon Bruce W Eckloff Michelle A T Hildebrandt Daniel J Schaid Eric D Wieben Richard M Weinshilboum

Cancer Res 2008 Jun;68(12):4791-801

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Medical School-Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6724	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490824	PMC

June 2008

Glutathione S-transferase T1 and M1: gene sequence variation and functional genomics.

Authors:

Ann M Moyer Oreste E Salavaggione Scott J Hebbring Irene Moon Michelle A T Hildebrandt Bruce W Eckloff Daniel J Schaid Eric D Wieben Richard M Weinshilboum

Clin Cancer Res 2007 Dec;13(23):7207-16

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0	Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-07-0635	DOI Listing

December 2007

Human hydroxysteroid sulfotransferase SULT2B1 pharmacogenomics: gene sequence variation and functional genomics.

Authors:

Yuan Ji Irene Moon Jelena Zlatkovic Oreste E Salavaggione Bianca A Thomae Bruce W Eckloff Eric D Wieben Daniel J Schaid Richard M Weinshilboum

J Pharmacol Exp Ther 2007 Aug 11;322(2):529-40. Epub 2007 May 11.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/jpet.107.122895	DOI Listing

August 2007

Glutathione S-transferase omega 1 and omega 2 pharmacogenomics.

Authors:

Baidehi Mukherjee Oreste E Salavaggione Linda L Pelleymounter Irene Moon Bruce W Eckloff Daniel J Schaid Eric D Wieben Richard M Weinshilboum

Drug Metab Dispos 2006 Jul 25;34(7):1237-46. Epub 2006 Apr 25.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/dmd.106.009613	DOI Listing

July 2006

Human methylenetetrahydrofolate reductase pharmacogenomics: gene resequencing and functional genomics.

Authors:

Yvette N Martin Oreste E Salavaggione Bruce W Eckloff Eric D Wieben Daniel J Schaid Richard M Weinshilboum

Pharmacogenet Genomics 2006 Apr;16(4):265-77

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1097/01.fpc.0000194423.20393.08	DOI Listing

April 2006

Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies.

Authors:

Thomas C Wood Oreste E Salavagionne Baidehi Mukherjee Liewei Wang Annette F Klumpp Bianca A Thomae Bruce W Eckloff Daniel J Schaid Eric D Wieben Richard M Weinshilboum

J Biol Chem 2006 Mar 6;281(11):7364-73. Epub 2006 Jan 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1074/jbc.M512227200	DOI Listing

March 2006

Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics.

Authors:

Judith A Gilbert Oreste E Salavaggione Yuan Ji Linda L Pelleymounter Bruce W Eckloff Eric D Wieben Matthew M Ames Richard M Weinshilboum

Clin Cancer Res 2006 Mar;12(6):1794-803

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0	Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-05-1969	DOI Listing