Publications by authors named "Eric C Holland"

100Publications

Incorporating genomic signatures into surgical and medical decision-making for elderly glioblastoma patients.

Neurosurg Focus 2020 Oct;49(4):E11

4Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.3171/2020.7.FOCUS20418DOI Listing
October 2020

Mathematical modeling of PDGF-driven glioma reveals the dynamics of immune cells infiltrating into tumors.

Neoplasia 2020 09 23;22(9):323-332. Epub 2020 Jun 23.

Department of Mathematical Sciences, New Mexico State University, 1780 E University Ave, Las Cruces, NM 88003, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2020.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322103PMC
September 2020

Stochastic growth pattern of untreated human glioblastomas predicts the survival time for patients.

Sci Rep 2020 04 20;10(1):6642. Epub 2020 Apr 20.

Department of Mathematical Sciences, New Mexico State University, 1780 E University Ave, Las Cruces, NM, 88003, USA.

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http://dx.doi.org/10.1038/s41598-020-63394-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171128PMC
April 2020

Variability in estimated gene expression among commonly used RNA-seq pipelines.

Sci Rep 2020 02 17;10(1):2734. Epub 2020 Feb 17.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.

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http://dx.doi.org/10.1038/s41598-020-59516-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026138PMC
February 2020

Translating Basic Science Discoveries into Improved Outcomes for Glioblastoma.

Clin Cancer Res 2020 Jun 14;26(11):2457-2460. Epub 2020 Feb 14.

Departments of Neurology, Pediatrics, Neurological Surgery, Brain Tumor Research Center and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-3924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269826PMC
June 2020

Mitotic Index Thresholds Do Not Predict Clinical Outcome for IDH-Mutant Astrocytoma.

J Neuropathol Exp Neurol 2019 11;78(11):1002-1010

Department of Pathology, Division of Neuropathology.

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http://dx.doi.org/10.1093/jnen/nlz082DOI Listing
November 2019

Phase II trial of an AKT inhibitor (perifosine) for recurrent glioblastoma.

J Neurooncol 2019 Sep 19;144(2):403-407. Epub 2019 Jul 19.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1007/s11060-019-03243-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493746PMC
September 2019

The molecular landscape of adult diffuse gliomas and relevance to clinical trials.

Oncotarget 2019 Mar 5;10(19):1758-1759. Epub 2019 Mar 5.

Patrick J. Cimino: Department of Pathology, Division of Neuropathology, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.18632/oncotarget.26750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443000PMC
March 2019

Targeted copy number analysis outperforms histologic grading in predicting patient survival for WHO grades II/III IDH-mutant astrocytomas.

Neuro Oncol 2019 06;21(6):819-821

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1093/neuonc/noz052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556841PMC
June 2019

A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.

Cell Rep 2018 06;23(13):3787-3797

Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA; Seattle Tumor Translational Research (STTR), Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA; Alvord Brain Tumor Center, University of Washington, Seattle, WA 98109, USA; Department of Neurosurgery, University of Washington, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411037PMC
June 2018

Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment.

Neuro Oncol 2018 02;20(3):355-366

Cellular Neurosciences, Max Delbrueck Center for Molecular Medicine in the Helmholtz Association and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1093/neuonc/nox165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817947PMC
February 2018

Putting Glioblastoma in Its Place: IRF3 Inhibits Invasion.

Trends Mol Med 2017 09 31;23(9):773-776. Epub 2017 Jul 31.

Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Seattle Tumor and Translational Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Neurological Surgery, Alvord Brain Tumor Center, University of Washington School of Medicine, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843370PMC
September 2017

Nanoparticle-mediated knockdown of DNA repair sensitizes cells to radiotherapy and extends survival in a genetic mouse model of glioblastoma.

Nanomedicine 2017 Oct 11;13(7):2131-2139. Epub 2017 Jun 11.

Department of Neurological Surgery, University of Washington, Seattle, WA, United States; Department of Materials Science and Engineering, University of Washington, Seattle, WA, United States; Department of Radiology, University of Washington, Seattle, WA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002851PMC
October 2017

Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery.

Acta Neuropathol Commun 2017 05 22;5(1):39. Epub 2017 May 22.

Division of Human Biology, and Seattle Tumor and Translational Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N., Mailstop C3-168, Seattle, WA, 98109, USA.

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http://dx.doi.org/10.1186/s40478-017-0443-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439117PMC
May 2017

Reply: Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.

Brain 2017 03;140(3):e17

Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1093/brain/aww325DOI Listing
March 2017

Tissue mechanics promote IDH1-dependent HIF1α-tenascin C feedback to regulate glioblastoma aggression.

Nat Cell Biol 2016 Dec 7;18(12):1336-1345. Epub 2016 Nov 7.

Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/ncb3429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361403PMC
December 2016

Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples.

Glia 2016 08;64(8):1416-36

Department of Cellular Neurosciences, Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Society, Berlin, Germany.

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http://dx.doi.org/10.1002/glia.23014DOI Listing
August 2016

High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive SERRS Molecular Imaging Probe.

Theranostics 2016 7;6(8):1075-84. Epub 2016 May 7.

1. Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;; 4. Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;; 5. Center for Molecular Imaging and Nanotechnology (CMINT), Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;; 6. Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.7150/thno.13842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893636PMC
October 2017

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.

Science 2016 May;352(6288):aad3018

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA. Department of Oncology, University of Lausanne, CH-1066, Lausanne, Switzerland. Ludwig Institute for Cancer Research, University of Lausanne, CH-1066, Lausanne, Switzerland.

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http://dx.doi.org/10.1126/science.aad3018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450629PMC
May 2016

Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma.

Cancer Cell 2016 05;29(5):669-683

Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 25229, USA; Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946168PMC
May 2016

Big data visualization identifies the multidimensional molecular landscape of human gliomas.

Proc Natl Acad Sci U S A 2016 May 26;113(19):5394-9. Epub 2016 Apr 26.

Division of Human Biology, and Solid Tumor and Translational Research, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, WA 98109; Department of Neurological Surgery, Alvord Brain Tumor Center, University of Washington, Seattle, WA 98195

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http://dx.doi.org/10.1073/pnas.1601591113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868421PMC
May 2016

Corticosteroids compromise survival in glioblastoma.

Brain 2016 05 28;139(Pt 5):1458-71. Epub 2016 Mar 28.

2 Department of Neurosciences at the Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, 44195, USA 3 Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA

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http://brain.oxfordjournals.org/content/brain/early/2016/03/
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http://pdfs.journals.lww.com/neurosurgery/2016/10000/Do_Cort
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http://dx.doi.org/10.1093/brain/aww046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006251PMC
May 2016

Glioma Stem-like Cells Keep Their H3.3 Variant Levels at Bay.

Cancer Cell 2015 Dec;28(6):679-680

Division of Human Biology, Solid Tumor and Translational Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Alvord Brain Tumor Center, University of Washington, Seattle, WA 98104, USA. Electronic address:

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http://www.cell.com/cancer-cell/pdf/S1535-6108(15)00432-8.pd
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http://linkinghub.elsevier.com/retrieve/pii/S153561081500432
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http://dx.doi.org/10.1016/j.ccell.2015.12.001DOI Listing
December 2015

Image-Guided Tumor Resection.

Cancer J 2015 May-Jun;21(3):206-12

From the *Research and Project Management, Blaze Bioscience, Inc; †Human Biology Division, Fred Hutchinson Cancer Research Center; and ‡Fred Hutchinson Cancer Research Center, Seattle, WA.

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http://dx.doi.org/10.1097/PPO.0000000000000113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459523PMC
February 2016

Personalized medicine for gliomas.

Surg Neurol Int 2015 13;6(Suppl 1):S89-95. Epub 2015 Feb 13.

Department of Neurological Surgery, University of Washington School of Medicine, Seattle, Washington, U.S.A ; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, U.S.A ; Alvord Brain Tumor Center, University of Washington, Seattle, Washington, U.S.A.

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http://surgicalneurologyint.com/surgicalint-articles/persona
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http://dx.doi.org/10.4103/2152-7806.151351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338492PMC
February 2015

Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.

Sci Transl Med 2015 Jan;7(271):271ra7

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Center for Molecular Imaging and Nanotechnology (CMINT), Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1126/scitranslmed.3010633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414254PMC
January 2015

Rethinking glioma treatment strategy.

Oncotarget 2014 Oct;5(20):9532-3

Division of Human Biology and Solid Tumor Translational Research (STTR), Fred Hutchinson Cancer Research Center, Department of Neurosurgery and Alvord Brain Tumor Center University of Washington.

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http://www.oncotarget.com/fulltext/2619
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259417PMC
http://dx.doi.org/10.18632/oncotarget.2619DOI Listing
October 2014

Oncogenic signaling is dominant to cell of origin and dictates astrocytic or oligodendroglial tumor development from oligodendrocyte precursor cells.

J Neurosci 2014 Oct;34(44):14644-51

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Rudbeck Laboratory, SE-75185 Uppsala, Sweden,

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http://dx.doi.org/10.1523/JNEUROSCI.2977-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608431PMC
October 2014

Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.

Cancer Cell 2014 Aug;26(2):288-300

Division of Human Biology and Solid Tumor Translational Research, Fred Hutchinson Cancer Research Center, Department of Neurosurgery and Alvord Brain Tumor Center, University of Washington, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143139PMC
August 2014

Guiding brain tumor resection using surface-enhanced Raman scattering nanoparticles and a hand-held Raman scanner.

ACS Nano 2014 Oct 22;8(10):9755-66. Epub 2014 Aug 22.

Department of Radiology, Memorial Sloan Kettering Cancer Center , New York, New York 10065, United States.

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http://dx.doi.org/10.1021/nn503948bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212801PMC
October 2014

Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma.

EMBO J 2014 Sep 24;33(18):1984-6. Epub 2014 Jul 24.

Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA Alvord Brain Tumor Center, University of Washington, Seattle, WA, USA.

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http://emboj.embopress.org/cgi/doi/10.15252/embj.201489479
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http://dx.doi.org/10.15252/embj.201489479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195767PMC
September 2014

The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions.

Glia 2014 Oct 4;62(10):1595-607. Epub 2014 Jun 4.

Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York; The Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1002/glia.22702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489138PMC
October 2014

In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift.

Proc Natl Acad Sci U S A 2014 Apr 24;111(14):5248-53. Epub 2014 Mar 24.

Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1321014111
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http://dx.doi.org/10.1073/pnas.1321014111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986190PMC
April 2014

Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth.

Cell Stem Cell 2014 Mar;14(3):357-69

Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Alvord Brain Tumor Center, University of Washington, Seattle, WA 98104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999042PMC
March 2014

Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules.

Cell 2014 Jan;156(3):603-616

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.cell.2013.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923371PMC
January 2014

A high-content assay strategy for the identification and profiling of ABCG2 modulators in live cells.

Assay Drug Dev Technol 2014 Jan-Feb;12(1):28-42. Epub 2013 Aug 30.

1 High-Throughput Screening Core Facility, Memorial Sloan-Kettering Cancer Center , New York, New York.

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http://dx.doi.org/10.1089/adt.2013.521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934439PMC
October 2014

A physical sciences network characterization of non-tumorigenic and metastatic cells.

Authors:
David B Agus Jenolyn F Alexander Wadih Arap Shashanka Ashili Joseph E Aslan Robert H Austin Vadim Backman Kelly J Bethel Richard Bonneau Wei-Chiang Chen Chira Chen-Tanyolac Nathan C Choi Steven A Curley Matthew Dallas Dhwanil Damania Paul C W Davies Paolo Decuzzi Laura Dickinson Luis Estevez-Salmeron Veronica Estrella Mauro Ferrari Claudia Fischbach Jasmine Foo Stephanie I Fraley Christian Frantz Alexander Fuhrmann Philippe Gascard Robert A Gatenby Yue Geng Sharon Gerecht Robert J Gillies Biana Godin William M Grady Alex Greenfield Courtney Hemphill Barbara L Hempstead Abigail Hielscher W Daniel Hillis Eric C Holland Arig Ibrahim-Hashim Tyler Jacks Roger H Johnson Ahyoung Joo Jonathan E Katz Laimonas Kelbauskas Carl Kesselman Michael R King Konstantinos Konstantopoulos Casey M Kraning-Rush Peter Kuhn Kevin Kung Brian Kwee Johnathon N Lakins Guillaume Lambert David Liao Jonathan D Licht Jan T Liphardt Liyu Liu Mark C Lloyd Anna Lyubimova Parag Mallick John Marko Owen J T McCarty Deirdre R Meldrum Franziska Michor Shannon M Mumenthaler Vivek Nandakumar Thomas V O'Halloran Steve Oh Renata Pasqualini Matthew J Paszek Kevin G Philips Christopher S Poultney Kuldeepsinh Rana Cynthia A Reinhart-King Robert Ros Gregg L Semenza Patti Senechal Michael L Shuler Srimeenakshi Srinivasan Jack R Staunton Yolanda Stypula Hariharan Subramanian Thea D Tlsty Garth W Tormoen Yiider Tseng Alexander van Oudenaarden Scott S Verbridge Jenny C Wan Valerie M Weaver Jonathan Widom Christine Will Denis Wirtz Jonathan Wojtkowiak Pei-Hsun Wu

Sci Rep 2013 ;3:1449

Center for Applied Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1038/srep01449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636513PMC
October 2013

Identification of global alteration of translational regulation in glioma in vivo.

PLoS One 2012 3;7(10):e46965. Epub 2012 Oct 3.

Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America .

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046965PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463531PMC
May 2013

The role of radiotherapy following gross-total resection of atypical meningiomas.

J Neurosurg 2012 Oct 24;117(4):679-86. Epub 2012 Aug 24.

Department of Neurological Surgery, The University of Miami Miller School of Medicine, Miami, FL, USA.

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https://thejns.org/view/journals/j-neurosurg/117/4/article-p
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http://dx.doi.org/10.3171/2012.7.JNS112113DOI Listing
October 2012

53BP1 is a haploinsufficient tumor suppressor and protects cells from radiation response in glioma.

Cancer Res 2012 Oct 21;72(20):5250-60. Epub 2012 Aug 21.

Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771704PMC
October 2012

Animal models for glioma drug discovery.

Expert Opin Drug Discov 2011 Dec 28;6(12):1271-83. Epub 2011 Oct 28.

University of Tennessee Health Science Center , Department of Clinical Pharmacy , 19 S. Manassas, Memphis, TN, 39103 , USA +901 448 1136 ; +901 448 6064 ;

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https://www.tandfonline.com/doi/full/10.1517/17460441.2011.6
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http://dx.doi.org/10.1517/17460441.2011.632628DOI Listing
December 2011

Low Concentration Microenvironments Enhance the Migration of Neonatal Cells of Glial Lineage.

Cell Mol Bioeng 2012 Jun;5(2)

Department of Biomedical Engineering, The City College of The City University of New York (CCNY), 160 Convent Avenue, Steinman Hall Room 403D, New York, NY 10031, USA ; Department of Biochemistry, The City Graduate Center of The City University of New York (CCNY), 365 Fifth Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1007/s12195-012-0226-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839109PMC
June 2012

Astrocyte-specific expression patterns associated with the PDGF-induced glioma microenvironment.

PLoS One 2012 29;7(2):e32453. Epub 2012 Feb 29.

Biochemistry, Cell, and Molecular Biology Program, Weill Medical College of Cornell University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032453PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290579PMC
July 2012

The brain tumor microenvironment.

Glia 2012 Mar;60(3):502-14

Brain Tumor Center and Department of Neurosurgery, Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1002/glia.21264DOI Listing
March 2012

PDGF in gliomas: more than just a growth factor?

Ups J Med Sci 2012 May 29;117(2):92-8. Epub 2012 Feb 29.

Department of Neurosurgery, Department of Cancer Biology and Genetics, and Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021, USA.

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http://dx.doi.org/10.3109/03009734.2012.654860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339541PMC
May 2012

Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia.

PLoS One 2012 11;7(1):e30059. Epub 2012 Jan 11.

Department of Neurological Surgery, Weill Cornell Brain Tumor Center, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030059PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256196PMC
May 2012

A mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis.

PLoS Comput Biol 2012 Jan 5;8(1):e1002337. Epub 2012 Jan 5.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.plos.org/10.1371/journal.pcbi.1002337
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http://dx.doi.org/10.1371/journal.pcbi.1002337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252265PMC
January 2012

The probable cell of origin of NF1- and PDGF-driven glioblastomas.

PLoS One 2011 9;6(9):e24454. Epub 2011 Sep 9.

Department of Regenerative Medicine, Cleveland Clinic, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024454PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170338PMC
June 2012

DNA damage response and growth factor signaling pathways in gliomagenesis and therapeutic resistance.

Cancer Res 2011 Sep 13;71(18):5945-9. Epub 2011 Sep 13.

Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-11-1245DOI Listing
September 2011

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas.

EMBO J 2011 Sep 13;30(19):4084-97. Epub 2011 Sep 13.

Department of Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/emboj.2011.259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209773PMC
September 2011

MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas.

FASEB J 2011 Dec 19;25(12):4138-49. Epub 2011 Aug 19.

Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065, USA.

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http://www.fasebj.org/doi/10.1096/fj.11-185033
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http://dx.doi.org/10.1096/fj.11-185033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236625PMC
December 2011

Cyclin D1 and cdk4 mediate development of neurologically destructive oligodendroglioma.

Cancer Res 2011 Oct 15;71(19):6174-83. Epub 2011 Aug 15.

Program in Molecular Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-11-1031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185142PMC
October 2011