Publications by authors named "Erdal Bedir"

70Publications

Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative.

Chem Res Toxicol 2020 Nov 2;33(11):2880-2891. Epub 2020 Nov 2.

Department of Bioengineering, Izmir Institute of Technology, 35430 Urla-İzmir, Turkey.

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http://dx.doi.org/10.1021/acs.chemrestox.0c00339DOI Listing
November 2020

Adjuvant potency of Astragaloside VII embedded cholesterol nanoparticles for H3N2 influenza vaccine.

Turk J Biol 2020 13;44(5):304-314. Epub 2020 Oct 13.

Department of Bioengineering, Faculty of Engineering, İzmir Institute of Technology, İzmir Turkey.

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http://dx.doi.org/10.3906/biy-2003-49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585159PMC
October 2020

Investigations on the anti-ulcerogenic activity of Sideritis caesarea H. Duman, Aytaç & Başer.

J Ethnopharmacol 2020 Aug 30;258:112920. Epub 2020 Apr 30.

Ege University, Faculty of Pharmacy, Department of Pharmacognosy, Bornova, 35040, Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2020.112920DOI Listing
August 2020

Evaluation of the potential aphrodisiac activity of sesquiterpenoids from roots of Ferula huber-morathii Peşmen in male rats.

J Ethnopharmacol 2020 Jul 13;257:112868. Epub 2020 Apr 13.

Department of Bioengineering, Faculty of Engineering, Izmir Institute of Technology, 35430 Urla, İzmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2020.112868DOI Listing
July 2020

Microbial Transformation of Cycloastragenol and Astragenol by Endophytic Fungi Isolated from Species.

J Nat Prod 2019 11 12;82(11):2979-2985. Epub 2019 Nov 12.

Department of Bioengineering, Faculty of Engineering , Izmir Institute of Technology , 35430 Urla-Izmir , Turkey.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00336DOI Listing
November 2019

Development of adjuvant nanocarrier systems for seasonal influenza A (H3N2) vaccine based on Astragaloside VII and gum tragacanth (APS).

Vaccine 2019 06 30;37(28):3638-3645. Epub 2019 May 30.

Izmir Institute of Technology, Faculty of Engineering, Department of Bioengineering, 35433 Gülbahçe, Urla, Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2019.05.038DOI Listing
June 2019

Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of M. Bieb. extracts.

Saudi Pharm J 2019 May 2;27(4):525-531. Epub 2019 Feb 2.

Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

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http://dx.doi.org/10.1016/j.jsps.2019.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488826PMC
May 2019

Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.

Chem Biol Interact 2019 Jul 3;307:167-178. Epub 2019 May 3.

Department of Bioengineering, Izmir Institute of Technology, Urla, 35430, Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.04.035DOI Listing
July 2019

Biotransformation of Neoruscogenin by the Endophytic Fungus Alternaria eureka.

J Nat Prod 2018 06 12;81(6):1357-1367. Epub 2018 Jun 12.

Department of Bioengineering, Faculty of Engineering , Izmir Institute of Technology , 35430 Urla - Izmir , Turkey.

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http://dx.doi.org/10.1021/acs.jnatprod.7b00898DOI Listing
June 2018

Biotransformation of ruscogenins by Cunninghamella blakesleeana NRRL 1369 and neoruscogenin by endophytic fungus Neosartorya hiratsukae.

Phytochemistry 2018 Aug 22;152:1-9. Epub 2018 Apr 22.

Department of Bioengineering, Faculty of Engineering, Izmir Institute of Technology, 35430 Urla, Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2018.04.002DOI Listing
August 2018

Biotransformation of cyclocanthogenol by the endophytic fungus Alternaria eureka 1E1BL1.

Phytochemistry 2018 Jul 17;151:91-98. Epub 2018 Apr 17.

Department of Bioengineering, Faculty of Engineering, Izmir Institute of Technology, 35430 Urla-Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2018.04.006DOI Listing
July 2018

Secondary metabolites from Astragalus karjaginii BORISS and the evaluation of their effects on cytokine release and hemolysis.

Fitoterapia 2017 Oct 18;122:26-33. Epub 2017 Aug 18.

Department of Bioengineering, Faculty of Engineering, Izmir Institute of Technology, Urla, 35430 Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2017.08.008DOI Listing
October 2017

Specialized metabolites from the aerial parts of Centaurea polyclada DC.

Phytochemistry 2017 Nov;143:12-18

Department of Bioengineering, Faculty of Engineering, Izmir Institute of Technology, 35430, Urla, Izmir, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2017.07.002DOI Listing
November 2017

Effects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα.

Chem Res Toxicol 2016 Mar 26;29(3):415-20. Epub 2016 Feb 26.

VA Tennessee Valley Healthcare System , Nashville, Tennessee 37212, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.6b00009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864862PMC
March 2016

Two rare quinone-type metabolites from the fungus Septofusidium berolinense and their biological activities.

J Antibiot (Tokyo) 2016 Feb 2;69(2):111-3. Epub 2015 Sep 2.

Department of Bioengineering, Faculty of Engineering, Ege University, Izmir, Turkey.

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http://dx.doi.org/10.1038/ja.2015.84DOI Listing
February 2016

Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016.

J Antibiot (Tokyo) 2016 Jan 1;69(1):51-6. Epub 2015 Jul 1.

Ege University, Department of Bioengineering, Izmir, Turkey.

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http://dx.doi.org/10.1038/ja.2015.72DOI Listing
January 2016

An analytical approach based on ESI-MS, LC-MS and PCA for the quali-quantitative analysis of cycloartane derivatives in Astragalus spp.

J Pharm Biomed Anal 2013 Nov 8;85:46-54. Epub 2013 Jul 8.

Dipartimento di Farmacia, Università degli Studi di Salerno, Via Giovanni Paolo II, n. 132, 84084 Fisciano, SA, Italy.

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http://dx.doi.org/10.1016/j.jpba.2013.06.021DOI Listing
November 2013

Unusual secondary metabolites from Astragalus halicacabus LAM.

Chem Biodivers 2013 Jul;10(7):1328-34

Ege University, Faculty of Science, Department of Chemistry, Bornova, 35100, İzmir, Turkey.

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http://dx.doi.org/10.1002/cbdv.201200436DOI Listing
July 2013

Microbial transformation of cycloastragenol.

Phytochemistry 2013 Apr 26;88:99-104. Epub 2013 Jan 26.

Ege University, Faculty of Engineering, Department of Bioengineering, 35100 Bornova, İzmir, Turkey.

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http://dx.doi.org/10.1016/j.phytochem.2012.12.007DOI Listing
April 2013

Saponins from Astragalus hareftae (NAB.) SIRJ.

Phytochemistry 2012 Dec 25;84:147-53. Epub 2012 Aug 25.

Department of Chemistry, Faculty of Science, Ege University, 35100 Bornova, İzmir, Turkey.

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http://linkinghub.elsevier.com/retrieve/pii/S003194221200338
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http://dx.doi.org/10.1016/j.phytochem.2012.07.015DOI Listing
December 2012

Triterpene glycosides from Astragalus angustifolius.

Planta Med 2012 May 21;78(7):720-9. Epub 2012 Mar 21.

Department of Chemistry, Faculty of Science, Ege University, Bornova, Izmir, Turkey.

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https://www.thieme-connect.com/products/ejournals/pdf/10.105
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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0031-1298337
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http://dx.doi.org/10.1055/s-0031-1298337DOI Listing
May 2012

Analysis of saponins and phenolic compounds as inhibitors of α-carbonic anhydrase isoenzymes.

J Enzyme Inhib Med Chem 2013 Apr 3;28(2):412-7. Epub 2012 Feb 3.

Department of Chemistry, Faculty of Science, Ege University, Bornova, İzmir, Turkey.

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http://dx.doi.org/10.3109/14756366.2011.651464DOI Listing
April 2013

Evaluation of the immunomodulatory properties in mice and in vitro anti-inflammatory activity of cycloartane type saponins from Astragalus species.

J Ethnopharmacol 2012 Jan 6;139(2):574-81. Epub 2011 Dec 6.

Ege University, Faculty of Engineering, Bioengineering Department, Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1016/j.jep.2011.11.053DOI Listing
January 2012

Identification of hypoglycaemic compounds from berries of Juniperus oxycedrus subsp. oxycedrus through bioactivity guided isolation technique.

J Ethnopharmacol 2012 Jan 29;139(1):110-8. Epub 2011 Oct 29.

Gazi University, Faculty of Pharmacy, Department of Pharmacognosy, 06330, Etiler, Ankara, Turkey.

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http://dx.doi.org/10.1016/j.jep.2011.10.027DOI Listing
January 2012

ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line.

Biochem Biophys Res Commun 2011 Jun 23;409(4):738-44. Epub 2011 May 23.

Ege University, Faculty of Engineering, Department of Bioengineering, Cancer Biology Laboratory, 35100 Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1016/j.bbrc.2011.05.078DOI Listing
June 2011

Cycloartane glycosides from Astragalus aureus.

Phytochemistry 2011 Jun 4;72(8):761-8. Epub 2011 Mar 4.

Department of Chemistry, Faculty of Science, Ege University, Bornova-İzmir, Turkey.

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http://dx.doi.org/10.1016/j.phytochem.2011.02.006DOI Listing
June 2011

Adjuvant effects of Astragalus saponins macrophyllosaponin B and astragaloside VII.

J Ethnopharmacol 2011 Apr 4;134(3):897-903. Epub 2011 Feb 4.

Ege University, Faculty of Engineering, Bioengineering Department, 35100 Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1016/j.jep.2011.01.054DOI Listing
April 2011

In vitro growth stimulatory and in vivo wound healing studies on cycloartane-type saponins of Astragalus genus.

J Ethnopharmacol 2011 Apr 1;134(3):844-50. Epub 2011 Feb 1.

Department of Bioengineering, Engineering Faculty, Ege University, Bornova, 35100 İzmir, Turkey.

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http://dx.doi.org/10.1016/j.jep.2011.01.030DOI Listing
April 2011

Phenolic Glycosides with antiproteasomal activity from Centaurea urvillei DC. subsp. urvillei.

Carbohydr Res 2010 Nov 7;345(17):2529-33. Epub 2010 Sep 7.

Department of Chemistry, Faculty of Science, Ege University, Bornova, 35100 Izmir, Turkey.

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https://linkinghub.elsevier.com/retrieve/pii/S00086215100037
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http://dx.doi.org/10.1016/j.carres.2010.09.002DOI Listing
November 2010

Biotransformation of cycloastragenol by Cunninghamella blakesleeana NRRL 1369 resulting in a novel framework.

Org Lett 2010 Oct;12(19):4252-5

Department of Bioengineering, Ege University, 35100 Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1021/ol101642aDOI Listing
October 2010

Alpha-glucosidase inhibitory constituents of Linaria kurdica subsp. eriocalyx.

Nat Prod Commun 2010 Jun;5(6):841-4

Department of Chemistry, Faculty of Science, Ege University, Bornova, Izmir 35100, Turkey.

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June 2010

Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines.

Plant Foods Hum Nutr 2010 Jun;65(2):158-63

Department of Bioengineering, Faculty of Engineering, Ege University, 35100, Bornova, Izmir, Turkey.

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http://link.springer.com/10.1007/s11130-010-0166-4
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http://dx.doi.org/10.1007/s11130-010-0166-4DOI Listing
June 2010

Cytotoxic naphthoquinones from Alkanna cappadocica ( perpendicular).

J Nat Prod 2010 May;73(5):860-4

Department of Bioengineering, Faculty of Engineering, Ege University, 35100 Bornova-Izmir, Turkey.

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http://dx.doi.org/10.1021/np900778jDOI Listing
May 2010

Bioassay-guided isolation of antibacterial and cytotoxic compounds from the mesophilic Actinomycete M-33-5.

Nat Prod Commun 2010 Feb;5(2):249-52

Department of Biology, Faculty of Science, Ege University, Bornova, 35100 Izmir, Turkey.

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February 2010

Triterpene glycosides from Astragalus icmadophilus.

Phytochemistry 2010 Jun 16;71(8-9):956-63. Epub 2010 Mar 16.

Ege University, Faculty of Science, Department of Chemistry, Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1016/j.phytochem.2010.02.014DOI Listing
June 2010

Triterpenoid saponins from Astragalus wiedemannianus Fischer.

Phytochemistry 2010 Apr 12;71(5-6):658-62. Epub 2010 Jan 12.

Ege University, Faculty of Science, Department of Chemistry, Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1016/j.phytochem.2009.11.013DOI Listing
April 2010

Triterpene glycosides from Agrostemma gracilis.

Phytochemistry 2010 Apr 6;71(5-6):663-8. Epub 2010 Jan 6.

Ege University, Faculty of Science, Department of Chemistry, Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1016/j.phytochem.2009.12.001DOI Listing
April 2010

Monoterpenoid glucoindole alkaloids and iridoids from Pterocephalus pinardii.

Magn Reson Chem 2010 Mar;48(3):239-43

Department of Chemistry, Faculty of Science, Ege University, Bornova, 35100 Izmir, Turkey.

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http://dx.doi.org/10.1002/mrc.2559DOI Listing
March 2010

Cycloartane-type glycosides from Astragalus amblolepis.

Phytochemistry 2009 Mar 6;70(5):628-34. Epub 2009 Apr 6.

Ege University, Faculty of Science, Department of Chemistry, Bornova, 35100 Izmir, Turkey.

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http://dx.doi.org/10.1016/j.phytochem.2009.03.006DOI Listing
March 2009

Tryptamine derived amides with thiazole ring system from Thermoactinomyces strain TA66-2.

Magn Reson Chem 2008 Jan;46(1):80-3

Science Technology Center (EBILTEM), Ege University, 35100 Bornova, Izmir, Turkey.

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http://dx.doi.org/10.1002/mrc.2101DOI Listing
January 2008

Chionaeosides A-D, triterpene saponins from Paronychia chionaea.

J Nat Prod 2007 Nov 19;70(11):1830-3. Epub 2007 Oct 19.

Department of Chemistry, Faculty of Sciences, Ege University, Bornova, Izmir, 35100 Turkey.

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http://dx.doi.org/10.1021/np0704607DOI Listing
November 2007

Determination of phenolic content and antioxidant activity of extracts obtained from Rosmarinus officinalis' calli.

J Plant Physiol 2007 Nov;164(11):1536-42

Ege University Science and Technology Center, 35100 Bornova-Izmir, Turkey.

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http://dx.doi.org/10.1016/j.jplph.2007.05.013DOI Listing
November 2007

Determination of naphthazarin derivatives in endemic Turkish Alkanna species by reversed phase high performance liquid chromatography.

Planta Med 2007 Mar 22;73(3):267-72. Epub 2007 Feb 22.

Department of Bioengineering, Faculty of Engineering, Ege University, Izmir, Turkey.

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http://dx.doi.org/10.1055/s-2007-967110DOI Listing
March 2007

Bioactive constituents from Turkish Pimpinella species.

Chem Biodivers 2005 Feb;2(2):221-32

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

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http://dx.doi.org/10.1002/cbdv.200590005DOI Listing
February 2005

Elemanolide sesquiterpenes and eudesmane sesquiterpene glycosides from Centaurea hierapolitana.

Phytochemistry 2007 Mar 28;68(5):609-15. Epub 2006 Nov 28.

Department of Pharmaceutical Botany, Ege University, 35100 Bornova-Izmir, Turkey.

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http://dx.doi.org/10.1016/j.phytochem.2006.10.013DOI Listing
March 2007

Gas chromatographic-mass spectrometric analysis of essential oils from Pimpinella species gathered from Central and Northern Turkey.

J Chromatogr A 2006 Jun 17;1117(2):194-205. Epub 2006 Apr 17.

USDA-ARS-NPURU, The University of Mississippi, University, MS 38677, USA.

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http://dx.doi.org/10.1016/j.chroma.2006.03.075DOI Listing
June 2006

Secondary metabolites from Phlomis oppositiflora.

Nat Prod Res 2005 Jul;19(5):493-501

Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey.

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http://dx.doi.org/10.1080/14786410412331280069DOI Listing
July 2005

Melanin: dietary mucosal immune modulator from Echinacea and other botanical supplements.

Int Immunopharmacol 2005 Apr;5(4):637-47

National Center for Natural Products Research, University of Mississippi, University, MS 38677, USA.

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http://dx.doi.org/10.1016/j.intimp.2004.12.011DOI Listing
April 2005

Effects of triterpene saponins from Astragalus species on in vitro cytokine release.

J Ethnopharmacol 2005 Jan;96(1-2):71-7

Faculty of Pharmacy, Gazi University, Hipodrom, 06330 Ankara, Turkey.

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https://linkinghub.elsevier.com/retrieve/pii/S03788741040045
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http://dx.doi.org/10.1016/j.jep.2004.08.036DOI Listing
January 2005

Antioxidant lignans from Larrea tridentata.

Phytochemistry 2004 Sep;65(17):2499-505

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS 38677, USA.

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http://dx.doi.org/10.1016/j.phytochem.2004.07.009DOI Listing
September 2004

Inhibition of human cytochromes P450 by components of Ginkgo biloba.

J Pharm Pharmacol 2004 Aug;56(8):1039-44

Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA 02111, USA.

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http://dx.doi.org/10.1211/0022357044021DOI Listing
August 2004

A new antimalarial quassinoid from Simaba orinocensis.

J Nat Prod 2004 May;67(5):772-7

Departments of Pharmacognosy and Pharmacology, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA.

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http://dx.doi.org/10.1021/np030524nDOI Listing
May 2004

Synthesis, anti-inflammatory and analgesic activity of some new 4(3H)-quinazolinone derivatives.

Arch Pharm (Weinheim) 2004 Feb;337(2):96-104

Hacettepe University, Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Ankara, Turkey.

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http://dx.doi.org/10.1002/ardp.200200752DOI Listing
February 2004

Antifungal clerodane diterpenes from Macaranga monandra (L) Muell. et Arg. (Euphorbiaceae).

J Agric Food Chem 2003 Dec;51(26):7607-10

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA.

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http://dx.doi.org/10.1021/jf034682wDOI Listing
December 2003

Antimicrobial compounds from Pimpinella species growing in Turkey.

Planta Med 2003 Oct;69(10):933-8

Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey.

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http://dx.doi.org/10.1055/s-2003-45103DOI Listing
October 2003

Eurycomaoside: a new quassinoid-type glycoside from the roots of Eurycoma longifolia.

Chem Pharm Bull (Tokyo) 2003 Nov;51(11):1301-3

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, MS 38677, USA.

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http://dx.doi.org/10.1248/cpb.51.1301DOI Listing
November 2003

Wiedemanniosides A-E: new phenylethanoid glycosides from the roots of Verbascum wiedemannianum.

Planta Med 2003 Sep;69(9):814-9

Faculty of Pharmacy, Department of Pharmacognosy, Hacettepe University, TR-06100 Ankara, Turkey.

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http://dx.doi.org/10.1055/s-2003-43214DOI Listing
September 2003

Neo-clerodane diterpenoids and phenylethanoid glycosides from Teucrium chamaedrys L.

Phytochemistry 2003 Aug;63(8):977-83

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, MS 38677, USA.

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http://dx.doi.org/10.1016/s0031-9422(03)00378-9DOI Listing
August 2003

Antiparasitic alkaloids from Psychotria klugii.

J Nat Prod 2003 Jul;66(7):962-7

National Center for Natural Products Research and Department of Pharmacology, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA.

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http://pubs.acs.org/doi/abs/10.1021/np030086k
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http://dx.doi.org/10.1021/np030086kDOI Listing
July 2003

The role of chemical fingerprinting: application to Ephedra.

Phytochemistry 2003 Mar;62(6):911-8

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

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http://dx.doi.org/10.1016/s0031-9422(02)00716-1DOI Listing
March 2003

Biologically active secondary metabolites from Ginkgo biloba.

J Agric Food Chem 2002 May;50(11):3150-5

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, and Department of Pharmacology and Pharmacognosy, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, USA.

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http://dx.doi.org/10.1021/jf011682sDOI Listing
May 2002