Publications by authors named "Eran Eyal"

48Publications

Whole exome sequencing (WES) approach for diagnosing primary immunodeficiencies (PIDs) in a highly consanguineous community.

Clin Immunol 2020 05 3;214:108376. Epub 2020 Mar 3.

Pediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, "Edmond and Lily Safra" Children's Hospital, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2020.108376DOI Listing
May 2020

Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With Mutation.

Front Immunol 2019 17;10:1672. Epub 2019 Jul 17.

The National Lab for Diagnosing SCID - The Israeli Newborn Screening Program, Pediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, Sheba Medical Center, Edmond and Lily Safra Children's Hospital, Israel Ministry of Health, Tel HaShomer, Israel.

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http://dx.doi.org/10.3389/fimmu.2019.01672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650764PMC
September 2020

c.259A>C in the fibrinogen gene of alpha chain () is a fibrinogen with thrombotic phenotype.

Appl Clin Genet 2019 28;12:27-33. Epub 2019 Feb 28.

Cancer Research Center, Wohl Institute of Translational Medicine, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.2147/TACG.S190599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400116PMC
February 2019

Congenital Sucrase-isomaltase Deficiency: A Novel Compound Heterozygous Mutation Causing Aberrant Protein Localization.

J Pediatr Gastroenterol Nutr 2017 05;64(5):770-776

*Division of Pediatric Gastroenterology, Hepatology and Nutrition, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel †Cincinnati Children's Hospital Medical Center, Cincinnati, OH ‡Cancer Research Center §Institute of Pathology, Sheba Medical Center, Tel Hashomer ||Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv ¶Metabolic Disease Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1097/MPG.0000000000001424DOI Listing
May 2017

A Novel Mutation in a Critical Region for the Methyl Donor Binding in DNMT3B Causes Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome (ICF).

J Clin Immunol 2016 11 12;36(8):801-809. Epub 2016 Oct 12.

Pediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel-Hashomer, Ramat Gan, Israel.

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http://link.springer.com/10.1007/s10875-016-0340-z
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http://dx.doi.org/10.1007/s10875-016-0340-zDOI Listing
November 2016

Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.

J Exp Med 2016 07 18;213(8):1429-40. Epub 2016 Jul 18.

Pediatric Department A and Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel The Wohl Institute for Translational Medicine, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel

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http://dx.doi.org/10.1084/jem.20151618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986528PMC
July 2016

Loss of function of NaPiIIa causes nephrocalcinosis and possibly kidney insufficiency.

Pediatr Nephrol 2016 12 4;31(12):2289-2297. Epub 2016 Jul 4.

Institute of Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00467-016-3443-0DOI Listing
December 2016

e23D: database and visualization of A-to-I RNA editing sites mapped to 3D protein structures.

Bioinformatics 2016 07 19;32(14):2213-5. Epub 2016 Apr 19.

Cancer Research Center, Sheba Medical Center, Ramat-Gan, Israel Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

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http://dx.doi.org/10.1093/bioinformatics/btw204DOI Listing
July 2016

TECPR2 mutations cause a new subtype of familial dysautonomia like hereditary sensory autonomic neuropathy with intellectual disability.

Eur J Paediatr Neurol 2016 Jan 22;20(1):69-79. Epub 2015 Oct 22.

Pediatric Neurology Unit, Edmond and Lily Safra Children's Hospital, The Chaim Sheba Med. Ctr., Israel; The Sackler School of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10903798150017
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http://dx.doi.org/10.1016/j.ejpn.2015.10.003DOI Listing
January 2016

High metallothionein predicts poor survival in glioblastoma multiforme.

BMC Med Genomics 2015 Oct 22;8:68. Epub 2015 Oct 22.

Pediatric Hemato-Oncology, Edmond and Lilly Safra Children's Hospital and Cancer Research Center, Sheba Medical Center, Tel Hashomer affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12920-015-0137-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618994PMC
October 2015

The anisotropic network model web server at 2015 (ANM 2.0).

Bioinformatics 2015 May 6;31(9):1487-9. Epub 2015 Jan 6.

Cancer Research Institute, Sheba Medical Center, 2 Sheba Rd, Ramat Gan 52621, Israel and Department of Computational and System Biology, University of Pittsburgh, 3501 Fifth Ave, Pittsburgh, PA 15213, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btu847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410662PMC
May 2015

Characterizing of functional human coding RNA editing from evolutionary, structural, and dynamic perspectives.

Proteins 2014 Nov 3;82(11):3117-31. Epub 2014 Sep 3.

Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, 52621, Ramat Gan, Israel; The Everard & Mina Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, 52900, Israel.

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http://dx.doi.org/10.1002/prot.24672DOI Listing
November 2014

Detection of BCR-ABL1 mutations in chronic myeloid leukaemia by massive parallel sequencing.

Br J Haematol 2013 Feb 17;160(4):477-86. Epub 2012 Dec 17.

Cancer Research Centre, Chaim Sheba Medical Centre, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1111/bjh.12171DOI Listing
February 2013

Cooperative dynamics of proteins unraveled by network models.

Wiley Interdiscip Rev Comput Mol Sci 2011 May-Jun;1(3):426-439. Epub 2011 Apr 11.

Department of Computational & Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/wcms.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059977PMC
April 2011

Global dynamics of proteins: bridging between structure and function.

Annu Rev Biophys 2010 ;39:23-42

Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.biophys.093
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http://dx.doi.org/10.1146/annurev.biophys.093008.131258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938190PMC
July 2010

Principal component analysis of native ensembles of biomolecular structures (PCA_NEST): insights into functional dynamics.

Bioinformatics 2009 Mar 15;25(5):606-14. Epub 2009 Jan 15.

University of Tokyo, Institute of Molecular and Cellular Bioscience, Tokyo, Japan.

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http://dx.doi.org/10.1093/bioinformatics/btp023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647834PMC
March 2009

Analysis of correlated mutations in HIV-1 protease using spectral clustering.

Bioinformatics 2008 May 28;24(10):1243-50. Epub 2008 Mar 28.

Department of Computational Biology, School of Medicine, University of Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1093/bioinformatics/btn110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373918PMC
May 2008

Toward a molecular understanding of the anisotropic response of proteins to external forces: insights from elastic network models.

Biophys J 2008 May 25;94(9):3424-35. Epub 2008 Jan 25.

Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1529/biophysj.107.120733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292382PMC
May 2008

Anisotropic fluctuations of amino acids in protein structures: insights from X-ray crystallography and elastic network models.

Bioinformatics 2007 Jul;23(13):i175-84

Department of Computational Biology, School of Medicine, University of Pittsburgh, Suite 3064, Biomedical Science Tower 3, 3051 Fifth Ave., Pittsburgh, PA 15213, USA.

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https://academic.oup.com/bioinformatics/article/23/13/i175/2
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http://dx.doi.org/10.1093/bioinformatics/btm186DOI Listing
July 2007

Refining intra-protein contact prediction by graph analysis.

BMC Bioinformatics 2007 May 24;8 Suppl 5:S6. Epub 2007 May 24.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1186/1471-2105-8-S5-S6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892094PMC
May 2007

Insights into equilibrium dynamics of proteins from comparison of NMR and X-ray data with computational predictions.

Structure 2007 Jun;15(6):741-9

Department of Computational Biology, School of Medicine, University of Pittsburgh, Biomedical Science Tower 3, 3051 Fifth Avenue, Pittsburgh, PA 15213, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096921260700183
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http://dx.doi.org/10.1016/j.str.2007.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760440PMC
June 2007

Rapid assessment of correlated amino acids from pair-to-pair (P2P) substitution matrices.

Bioinformatics 2007 Jul 12;23(14):1837-9. Epub 2007 May 12.

Department of Computational Biology, School of Medicine, University of Pittsburgh, 3501 Fifth Avenue, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/bioinformatics/btm256DOI Listing
July 2007

A pair-to-pair amino acids substitution matrix and its applications for protein structure prediction.

Proteins 2007 Apr;67(1):142-53

Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1002/prot.21223DOI Listing
April 2007

RUN-CBFbeta interaction in C. elegans: computational prediction and experimental verification.

J Biomol Struct Dyn 2007 Feb;24(4):343-58

Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1080/07391102.2007.10507124DOI Listing
February 2007

Anisotropic network model: systematic evaluation and a new web interface.

Bioinformatics 2006 Nov 23;22(21):2619-27. Epub 2006 Aug 23.

Department of Computational Biology, School of Medicine, University of Pittsburgh, PA 15213, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btl448DOI Listing
November 2006

The limit of accuracy of protein modeling: influence of crystal packing on protein structure.

J Mol Biol 2005 Aug;351(2):431-42

Department of Plant Sciences, Weizmann Institute of Science, 76100, Rehovot, Israel.

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http://dx.doi.org/10.1016/j.jmb.2005.05.066DOI Listing
August 2005

SPACE: a suite of tools for protein structure prediction and analysis based on complementarity and environment.

Nucleic Acids Res 2005 Jul;33(Web Server issue):W39-43

Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1093/nar/gki398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160159PMC
July 2005

Importance of solvent accessibility and contact surfaces in modeling side-chain conformations in proteins.

J Comput Chem 2004 Apr;25(5):712-24

Department of Plant Sciences, Weizmann Institute of Science, 76100, Rehovot, Israel.

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http://doi.wiley.com/10.1002/jcc.10420
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http://dx.doi.org/10.1002/jcc.10420DOI Listing
April 2004

Protein side-chain rearrangement in regions of point mutations.

Proteins 2003 Feb;50(2):272-82

Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1002/prot.10276DOI Listing
February 2003