Enzo Martegani

Enzo Martegani

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Enzo Martegani

Publications by authors named "Enzo Martegani"

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Dynamic of VE-cadherin-mediated spermatid-Sertoli cell contacts in the mouse seminiferous epithelium.

Histochem Cell Biol 2018 Aug 25;150(2):173-185. Epub 2018 May 25.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1007/s00418-018-1682-9DOI Listing
August 2018

Antagonism between salicylate and the cAMP signal controls yeast cell survival and growth recovery from quiescence.

Microb Cell 2018 Mar 26;5(7):344-356. Epub 2018 Mar 26.

Dipartimento di Biotecnologie e Bioscienze, Università Milano Bicocca, 20126 Milano, Italy.

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http://dx.doi.org/10.15698/mic2018.07.640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035838PMC
March 2018

Guidelines and recommendations on yeast cell death nomenclature.

Microb Cell 2018 Jan 1;5(1):4-31. Epub 2018 Jan 1.

Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.

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http://dx.doi.org/10.15698/mic2018.01.607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772036PMC
January 2018

Detection of cAMP and of PKA activity in Saccharomyces cerevisiae single cells using Fluorescence Resonance Energy Transfer (FRET) probes.

Biochem Biophys Res Commun 2017 06 19;487(3):594-599. Epub 2017 Apr 19.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy; SysBio Centre of Systems Biology, Piazza della Scienza 2, I-20126 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.04.097DOI Listing
June 2017

Involvement of Aif1 in apoptosis triggered by lack of Hxk2 in the yeast Saccharomyces cerevisiae.

FEMS Yeast Res 2016 May 18;16(3). Epub 2016 Feb 18.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, I-20126 Milan, Italy SysBio Centre of Systems Biology, Piazza della Scienza 2, I-20126 Milan, Italy

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http://dx.doi.org/10.1093/femsyr/fow016DOI Listing
May 2016

The transcription factor Swi4 is target for PKA regulation of cell size at the G1 to S transition in Saccharomyces cerevisiae.

Cell Cycle 2015 Aug 5;14(15):2429-38. Epub 2015 Jun 5.

a Dipartimento di Biotecnologie e Bioscienze ; Università di Milano Bicocca ; Milano , Italy.

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http://dx.doi.org/10.1080/15384101.2015.1055997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614678PMC
August 2015

The deubiquitinating enzyme UBPy/USP8 interacts with TrkA and inhibits neuronal differentiation in PC12 cells.

Exp Cell Res 2015 Apr 4;333(1):49-59. Epub 2015 Feb 4.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144827150003
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http://dx.doi.org/10.1016/j.yexcr.2015.01.019DOI Listing
April 2015

Peptide-nanoparticle ligation mediated by cutinase fusion for the development of cancer cell-targeted nanoconjugates.

Bioconjug Chem 2015 Apr 13;26(4):680-9. Epub 2015 Mar 13.

†Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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http://pubs.acs.org/doi/10.1021/acs.bioconjchem.5b00005
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http://dx.doi.org/10.1021/acs.bioconjchem.5b00005DOI Listing
April 2015

Monitoring yeast intracellular Ca2+ levels using an in vivo bioluminescence assay.

Cold Spring Harb Protoc 2015 Feb 2;2015(2):210-3. Epub 2015 Feb 2.

Laboratório de Bioquímica e Biotecnologia de Leveduras, Núcleo de Pesquisas em Ciências Biológicas, Escola de Farmácia, Universidade Federal de Ouro Preto, Campus do Morro do Cruzeiro, 35.400-000 Ouro Preto, Minas Gerais, Brazil.

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http://dx.doi.org/10.1101/pdb.prot076851DOI Listing
February 2015

Total cellular Ca2+ measurements in yeast using flame photometry.

Cold Spring Harb Protoc 2015 Feb 2;2015(2):214-6. Epub 2015 Feb 2.

Laboratório de Bioquímica e Biotecnologia de Leveduras, Núcleo de Pesquisas em Ciências Biológicas, Escola de Farmácia, Universidade Federal de Ouro Preto, Campus do Morro do Cruzeiro, 35.400-000 Ouro Preto, Minas Gerais, Brazil.

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http://dx.doi.org/10.1101/pdb.prot076869DOI Listing
February 2015

Measurement of calcium uptake in yeast using 45Ca.

Cold Spring Harb Protoc 2015 Feb 2;2015(2):217-8. Epub 2015 Feb 2.

Laboratório de Bioquímica e Biotecnologia de Leveduras, Núcleo de Pesquisas em Ciências Biológicas, Escola de Farmácia, Universidade Federal de Ouro Preto, Campus do Morro do Cruzeiro, 35.400-000 Ouro Preto, Minas Gerais, Brazil.

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http://dx.doi.org/10.1101/pdb.prot076877DOI Listing
February 2015

Nuclear Ras2-GTP controls invasive growth in Saccharomyces cerevisiae.

PLoS One 2013 14;8(11):e79274. Epub 2013 Nov 14.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079274PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828362PMC
November 2014

Yeast as a model for Ras signalling.

Methods Mol Biol 2014 ;1120:359-90

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1007/978-1-62703-791-4_23DOI Listing
September 2014

Methods to study the Ras2 protein activation state and the subcellular localization of Ras-GTP in Saccharomyces cerevisiae.

Methods Mol Biol 2014 ;1120:391-405

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1007/978-1-62703-791-4_24DOI Listing
September 2014

Lack of HXK2 induces localization of active Ras in mitochondria and triggers apoptosis in the yeast Saccharomyces cerevisiae.

Oxid Med Cell Longev 2013 5;2013:678473. Epub 2013 Sep 5.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, 20126 Milan, Italy ; SysBio Centre of Systems Biology, Piazza Della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1155/2013/678473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780702PMC
May 2014

Evidence for adenylate cyclase as a scaffold protein for Ras2-Ira interaction in Saccharomyces cerevisie.

Cell Signal 2014 May 8;26(5):1147-54. Epub 2014 Feb 8.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, 20126 Milan, Italy; SysBio Centre of Systems Biology, Piazza della Scienza 2, 20126 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.02.001DOI Listing
May 2014

Live-cell imaging of endogenous Ras-GTP shows predominant Ras activation at the plasma membrane and in the nucleus in Saccharomyces cerevisiae.

Int J Biochem Cell Biol 2013 Feb 2;45(2):384-94. Epub 2012 Nov 2.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1016/j.biocel.2012.10.013DOI Listing
February 2013

Simulation of the Ras/cAMP/PKA pathway in budding yeast highlights the establishment of stable oscillatory states.

Biotechnol Adv 2012 Jan-Feb;30(1):99-107. Epub 2011 Jun 29.

Università degli Studi di Milano-Bicocca, Dipartimento di Statistica, Milano, Italy.

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http://dx.doi.org/10.1016/j.biotechadv.2011.06.014DOI Listing
July 2012

Localization of Ras signaling complex in budding yeast.

Biochim Biophys Acta 2012 Jul 7;1823(7):1208-16. Epub 2012 May 7.

Department of Biotechnology and Biosciences, Umiversity of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1016/j.bbamcr.2012.04.016DOI Listing
July 2012

The role of feedback control mechanisms on the establishment of oscillatory regimes in the Ras/cAMP/PKA pathway in S. cerevisiae.

EURASIP J Bioinform Syst Biol 2012 Jul 20;2012(1):10. Epub 2012 Jul 20.

Università degli Studi di Milano, Dipartimento di Informatica, Via Comelico 39, 20135 Milano, Italy.

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http://dx.doi.org/10.1186/1687-4153-2012-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479052PMC
July 2012

PKA-dependent regulation of Cdc25 RasGEF localization in budding yeast.

FEBS Lett 2011 Dec 25;585(24):3914-20. Epub 2011 Oct 25.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1016/j.febslet.2011.10.032DOI Listing
December 2011

Glucose-induced calcium influx in budding yeast involves a novel calcium transport system and can activate calcineurin.

Cell Calcium 2011 Jun 21;49(6):376-86. Epub 2011 Apr 21.

Dep. Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1016/j.ceca.2011.03.006DOI Listing
June 2011

Activation of amyloid precursor protein processing by growth factors is dependent on Ras GTPase activity.

Neurochem Res 2011 Mar 15;36(3):392-8. Epub 2010 Dec 15.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, 20126, Milan, Italy.

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http://dx.doi.org/10.1007/s11064-010-0343-8DOI Listing
March 2011

The PH-PxxP domain of RalGPS2 promotes PC12 cells differentiation acting as a dominant negative for RalA GTPase activation.

Neurosci Res 2010 Mar 16;66(3):290-8. Epub 2009 Dec 16.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, Milan, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S016801020902072
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http://dx.doi.org/10.1016/j.neures.2009.11.013DOI Listing
March 2010

Structure-activity studies on arylamides and arysulfonamides Ras inhibitors.

Curr Cancer Drug Targets 2010 Mar;10(2):192-9

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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March 2010

Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).

Biochem Biophys Res Commun 2009 Sep 18;386(4):593-7. Epub 2009 Jun 18.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 20126 Milan, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2009.06.069DOI Listing
September 2009

Identification of novel RasGRF1 interacting partners by large-scale proteomic analysis.

J Mol Neurosci 2009 Mar 8;37(3):212-24. Epub 2008 Jul 8.

Department of Biomolecular Sciences and Biotechnology, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1007/s12031-008-9118-yDOI Listing
March 2009

Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast.

J Cell Sci 2009 Mar 10;122(Pt 5):706-15. Epub 2009 Feb 10.

Department of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.

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http://dx.doi.org/10.1242/jcs.042424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720921PMC
March 2009

The budding yeast RasGEF Cdc25 reveals an unexpected nuclear localization.

Biochim Biophys Acta 2008 Dec 27;1783(12):2363-74. Epub 2008 Sep 27.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126, Milan, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S016748890800309
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http://dx.doi.org/10.1016/j.bbamcr.2008.09.004DOI Listing
December 2008

Carbonyl cyanide m-chlorophenylhydrazone induced calcium signaling and activation of plasma membrane H(+)-ATPase in the yeast Saccharomyces cerevisiae.

FEMS Yeast Res 2008 Jun 8;8(4):622-30. Epub 2008 Apr 8.

Laboratório de Biologia Celular e Molecular, Núcleo de Pesquisas em Ciências Biológicas, Escola de Farmácia, Universidade Federal de Ouro Preto, Campus do Morro do Cruzeiro, Ouro Preto, MG - Brazil.

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http://dx.doi.org/10.1111/j.1567-1364.2008.00380.xDOI Listing
June 2008

Functional coupling of the mammalian EGF receptor to the Ras/cAMP pathway in the yeast Saccharomyces cerevisiae.

Curr Genet 2008 Mar 9;53(3):153-62. Epub 2008 Jan 9.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126, Milan, Italy.

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http://dx.doi.org/10.1007/s00294-007-0173-7DOI Listing
March 2008

Modeling and stochastic simulation of the Ras/cAMP/PKA pathway in the yeast Saccharomyces cerevisiae evidences a key regulatory function for intracellular guanine nucleotides pools.

J Biotechnol 2008 Feb 11;133(3):377-85. Epub 2007 Oct 11.

Università degli Studi di Milano-Bicocca, Dipartimento di Informatica, Sistemistica e Comunicazione, Viale Sarca 336, 20126 Milano, Italy.

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http://dx.doi.org/10.1016/j.jbiotec.2007.09.019DOI Listing
February 2008

The large N-terminal domain of Cdc25 protein of the yeast Saccharomyces cerevisiae is required for glucose-induced Ras2 activation.

FEMS Yeast Res 2007 Dec 29;7(8):1270-5. Epub 2007 Aug 29.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1111/j.1567-1364.2007.00300.xDOI Listing
December 2007

Glucose-derived Ras pathway inhibitors: evidence of Ras-ligand binding and Ras-GEF (Cdc25) interaction inhibition.

Chembiochem 2007 Aug;8(12):1376-9

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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http://dx.doi.org/10.1002/cbic.200700185DOI Listing
August 2007

Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase.

Exp Cell Res 2007 Jul 24;313(11):2293-307. Epub 2007 Mar 24.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, Milan, Italy.

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http://dx.doi.org/10.1016/j.yexcr.2007.03.016DOI Listing
July 2007

Calcium signaling and sugar-induced activation of plasma membrane H(+)-ATPase in Saccharomyces cerevisiae cells.

Biochem Biophys Res Commun 2006 May 23;343(4):1234-43. Epub 2006 Mar 23.

Laboratório de Biologia Celular e Molecular, Núcleo de Pesquisas em Ciências Biológicas, Departamento de Farmácia, Escola de Farmácia, Universidade Federal de Ouro Preto, Campus do Morro do Cruzeiro, 35.400-000 Ouro Preto, MG, Brazil.

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http://dx.doi.org/10.1016/j.bbrc.2006.03.078DOI Listing
May 2006

The N-terminal region of the Saccharomyces cerevisiae RasGEF Cdc25 is required for nutrient-dependent cell-size regulation.

Microbiology 2006 Apr;152(Pt 4):1231-42

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1099/mic.0.28683-0DOI Listing
April 2006

Recombinant human nerve growth factor with a marked activity in vitro and in vivo.

Proc Natl Acad Sci U S A 2005 Dec;102(51):18658-63

Laboratory of Neuroscience R. Levi-Montalcini, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1073/pnas.0508734102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317951PMC
December 2005

Design, synthesis and biological evaluation of sugar-derived Ras inhibitors.

Chembiochem 2005 Oct;6(10):1839-48

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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http://dx.doi.org/10.1002/cbic.200400420DOI Listing
October 2005

The deubiquitinating enzyme mUBPy interacts with the sperm-specific molecular chaperone MSJ-1: the relation with the proteasome, acrosome, and centrosome in mouse male germ cells.

Biol Reprod 2005 Jan 1;72(1):14-21. Epub 2004 Sep 1.

Dipartimento di Biologia, Università di Milano, 20133 Milan, Italy.

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http://dx.doi.org/10.1095/biolreprod.104.030866DOI Listing
January 2005

Design and characterization of a new class of inhibitors of ras activation.

Ann N Y Acad Sci 2004 Dec;1030:52-61

Laboratory of Molecular Biology, Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, Milan 20126, Italy.

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http://dx.doi.org/10.1196/annals.1329.007DOI Listing
December 2004

Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae.

J Biol Chem 2004 Nov 31;279(45):46715-22. Epub 2004 Aug 31.

Dipartimento di Biotecnologie e Bioscienze, Università Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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http://dx.doi.org/10.1074/jbc.M405136200DOI Listing
November 2004

Analysis of the gene expression profile of mouse male meiotic germ cells.

Gene Expr Patterns 2004 May;4(3):267-81

Dipartimento di Sanita Pubblica e Biologia Cellulare, Sezione di Anatomia, Universita di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.modgep.2003.11.003DOI Listing
May 2004

Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast.

Curr Genet 2004 Feb 15;45(2):83-9. Epub 2003 Nov 15.

Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1007/s00294-003-0465-5DOI Listing
February 2004

mUBPy and MSJ-1, a deubiquitinating enzyme and a molecular chaperone specifically expressed in testis, associate with the acrosome and centrosome in mouse germ cells.

Ann N Y Acad Sci 2002 Nov;973:5-7

Dipartimento di Biologia, Università di Milano, Via Celoria 26, 20133 Milano, Italy.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb04597.xDOI Listing
November 2002

Cloning and characterization of a new Ral-GEF expressed in mouse testis.

Ann N Y Acad Sci 2002 Nov;973:135-7

Dipartimento di Biotecnologie e Bioscienze, Universitá degli Studi di Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb04621.xDOI Listing
November 2002

Phospholipase C is required for glucose-induced calcium influx in budding yeast.

FEBS Lett 2002 Jun;520(1-3):133-8

Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1016/s0014-5793(02)02806-5DOI Listing
June 2002

Molecular cloning and transcriptional analysis of the start gene CDC25 of Saccharomyces cerevisiae.

EMBO J 1986 Sep;5(9):2363-2369

Dipartimento di Fisiologia e Biochimica Generali, Sezione di Biochimica Comparata, Universita' di Milano, via Celoria 26, 20133 Milano, Italy.

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1167121/pdf/emb
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1167121PMC
September 1986