Dr. Enrique Teran, MD, PhD - Universidad San Francisco de Quito - Professor

Dr. Enrique Teran

MD, PhD

Universidad San Francisco de Quito

Professor

Quito | Ecuador

Main Specialties: Pharmacology

ORCID logohttps://orcid.org/0000-0001-6979-5655


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Dr. Enrique Teran, MD, PhD - Universidad San Francisco de Quito - Professor

Dr. Enrique Teran

MD, PhD

Introduction

Dr. Teran is Professor at School of Medicine in the Universidad San Francisco de Quito (USFQ). He received his MD from Central University of Ecuador and his PhD from University College London in the UK. As pharmacologist, he has been working for more than 20 years on vascular factors, infectious diseases, oxidative stress and pharmacogenetics in Ecuadorian population. To reach this, he has develop a very well structure relationship with the Ecuadorian Ministry of Health and he has been successful in set up all necessary lab facilities to perform in house the majority of the analysis included in his studies. He also dedicated some of his time to the study of metabolic syndrome both in indigenous and mestizo population in Ecuador. Dr. Teran has been PI or co-Investigator on several university- and externally-funded grants, and then he has the expertise, leadership and motivation necessary to successfully carry out the proposed role in this proposal, as local counterpart.

Primary Affiliation: Universidad San Francisco de Quito - Quito , Ecuador

Specialties:


View Dr. Enrique Teran’s Resume / CV

Education

Jan 1998 - May 2002
University College London
PhD
Wolfson Institute for Biomedical Research
Oct 1988 - Jul 1996
Universidad Central del Ecuador
Medical Doctor (MD)
Facultad de Ciencias Medicas

Experience

Sep 2013 - Sep 2013
Universidad San Francisco de Quito
Associate Professor
Colegio de Ciencias de la Salud
Oct 2016
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Publications

45Publications

579Reads

1Profile Views

76PubMed Central Citations

Mitochondria and Coenzyme Q10 in the Pathogenesis of Preeclampsia.

Front Physiol 2018 15;9:1561. Epub 2018 Nov 15.

Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.

Hypertensive disorders during pregnancy constitute one of the main causes of maternal and perinatal morbidity and mortality across the world and particularly in developing countries such as Ecuador. However, despite its impact on public health, the primary pathophysiological processes involved are yet to be elucidated. It has been proposed, among other theories, that an abnormal placentation may induce an endothelial dysfunction, which is ultimately responsible for the final clinical manifestations. Mitochondria, particularly from trophoblastic cells, are responsible for the production of energy, which is extremely important for normal placentation. The malfunction in this supply of energy may produce higher levels of free radicals. In both production of energy and free radicals, coenzyme Q10 (CoQ10) plays a crucial role in electron transport. As such, the role of CoQ10 in the genesis and prevention of preeclampsia has become the focus of a number of research groups, including that of the authors. Developing an in-depth understanding of these mechanisms might allow us to design new and feasible strategies with which we can reduce preeclampsia, particularly in the Latin-American countries.

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http://dx.doi.org/10.3389/fphys.2018.01561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249996PMC
November 2018
5 Reads

"Cancer is in style": lifestyle change and the perceived impact of globalization on Andean indigenous communities in Ecuador.

Ethn Health 2018 Jul 4:1-15. Epub 2018 Jul 4.

e Department of Health Sciences , Northern Arizona University , Flagstaff , AZ , USA.

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http://dx.doi.org/10.1080/13557858.2018.1493437DOI Listing
July 2018
12 Reads
1.280 Impact Factor

Nebulization of antimicrobial agents in mechanically ventilated adults in 2017: an international cross-sectional survey.

Eur J Clin Microbiol Infect Dis 2018 Apr 9;37(4):785-794. Epub 2018 Jan 9.

Critical Care Department, Vall d'Hebron Institut of Research, Barcelona, Spain.

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http://link.springer.com/10.1007/s10096-017-3175-5
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http://dx.doi.org/10.1007/s10096-017-3175-5DOI Listing
April 2018
29 Reads
2 Citations
2.670 Impact Factor

Foreword from the guest editors.

Growth Horm IGF Res 2018 02 28;38. Epub 2017 Dec 28.

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http://dx.doi.org/10.1016/j.ghir.2017.12.014DOI Listing
February 2018
6 Reads
1.330 Impact Factor

Meeting Reports: The 2017-USFQ Biennial Meeting on Growth Hormone and IGF1 Research.

Pediatr Endocrinol Rev 2017 Dec;15(2):173-184

Oregon Health and Science University, Portland, Oregon, Stanford University, CA, USA.

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http://dx.doi.org/10.17458/per.vol15.2017.gtr.mr.2017usfqbiennialmeetingDOI Listing
December 2017
9 Reads

Post-earthquake Zika virus surge: Disaster and public health threat amid climatic conduciveness.

Sci Rep 2017 11 13;7(1):15408. Epub 2017 Nov 13.

Department of Global Health, College of Public Health, University of South Florida, Tampa, FL, USA.

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http://dx.doi.org/10.1038/s41598-017-15706-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684400PMC
November 2017
33 Reads
5.080 Impact Factor

Vascular Dysfunction in Mother and Offspring During Preeclampsia: Contributions from Latin-American Countries.

Curr Hypertens Rep 2017 Oct 6;19(10):83. Epub 2017 Oct 6.

Vascular Physiology Laboratory Group of Investigation in Tumor Angiogenesis (GIANT) Group of Research and Innovation in Vascular Health (GRIVAS Health) Basic Sciences Department Faculty of Sciences, Universidad del Bio-Bio, Chillan, Chile.

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http://dx.doi.org/10.1007/s11906-017-0781-7DOI Listing
October 2017
26 Reads
3.440 Impact Factor

Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans.

J Neurosci 2017 02 10;37(7):1696-1707. Epub 2017 Jan 10.

Leonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089,

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http://dx.doi.org/10.1523/JNEUROSCI.1929-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320603PMC
February 2017
29 Reads
3 Citations
6.344 Impact Factor

To Genotype or Phenotype for Personalized Medicine? CYP450 Drug Metabolizing Enzyme Genotype-Phenotype Concordance and Discordance in the Ecuadorian Population.

OMICS 2016 12 16;20(12):699-710. Epub 2016 Nov 16.

1 CICAB Clinical Research Centre, Extremadura University Hospital and Medical School , Badajoz, Spain .

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http://dx.doi.org/10.1089/omi.2016.0148DOI Listing
December 2016
15 Reads
3 Citations
2.362 Impact Factor

Sublingual misoprostol is as effective as intravenous oxytocin to reduce intra-operative blood loss during cesarean delivery in women living at high altitude.

J Matern Fetal Neonatal Med 2016 10;29(4):559-61. Epub 2015 Feb 10.

b Colegio de Ciencias de la Salud, Universidad San Francisco de Quito , Quito , Ecuador.

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http://dx.doi.org/10.3109/14767058.2015.1011115DOI Listing
September 2016
5 Reads

Five-Year Eradication of Hepatitis B Infection After an Outreach Immunization Program in the Waorani Population in the Ecuadorian Amazon.

Am J Trop Med Hyg 2016 09 5;95(3):670-3. Epub 2016 Jul 5.

Colegio de Ciencias de la Salud, Universidad San Francisco de Quito, Quito, Ecuador.

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http://dx.doi.org/10.4269/ajtmh.16-0248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014276PMC
September 2016
3 Reads
2.700 Impact Factor

Foreword from the editors.

Growth Horm IGF Res 2016 06;28

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http://dx.doi.org/10.1016/j.ghir.2016.04.002DOI Listing
June 2016
5 Reads
1.330 Impact Factor

Despite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives.

Growth Horm IGF Res 2016 06 5;28:76-8. Epub 2015 Aug 5.

Colegio de Ciencias de la Salud, Universidad San Francisco de Quito, Ecuador.

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http://dx.doi.org/10.1016/j.ghir.2015.08.002DOI Listing
June 2016
13 Reads
2 Citations
1.330 Impact Factor

Growth and growth hormone: An overview.

Growth Horm IGF Res 2016 06 23;28:3-5. Epub 2016 Feb 23.

Division of Pediatric Endocrinology and Diabetes, Icahn School of Medicine at Mount Sina, 1 Gustave L. Levy Place, NY, USA.

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http://dx.doi.org/10.1016/j.ghir.2016.02.004DOI Listing
June 2016
6 Reads
1 Citation
1.330 Impact Factor

Multiplex Phenotyping for Systems Medicine: A One-Point Optimized Practical Sampling Strategy for Simultaneous Estimation of CYP1A2, CYP2C9, CYP2C19, and CYP2D6 Activities Using a Cocktail Approach.

OMICS 2016 Feb 24;20(2):88-96. Epub 2015 Nov 24.

1 CICAB Clinical Research Centre, Extremadura University Hospital and Medical School , Badajoz, Spain .

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http://dx.doi.org/10.1089/omi.2015.0131DOI Listing
February 2016
11 Reads
3 Citations
2.362 Impact Factor

GH Receptor Deficiency in Ecuadorian Adults Is Associated With Obesity and Enhanced Insulin Sensitivity.

J Clin Endocrinol Metab 2015 Jul 18;100(7):2589-96. Epub 2015 May 18.

Universidad San Francisco de Quito (J.G.-A., E.T.), Quito, Ecuador; Instituto de Endocrinologia, Metabolismo y Repróduccion (J.G.-A., A.L.R., M.G.-A., C.G., P.P., L.N., J.S.), Quito Ecuador; University of Florida College of Medicine (A.L.R.), Gainesville, Florida 32608; Davis School of Gerontology (P.B., S.D.B., V.D.L.), University of Southern California, Los Angeles, California 90089; Experimental Gerontology Section (I.A., R.D.C.), Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224; and Longevity Institute (V.D.L.), University of Southern California, Los Angeles, California 90089.

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http://dx.doi.org/10.1210/jc.2015-1678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490304PMC
July 2015
37 Reads
9 Citations
6.210 Impact Factor

Meeting Report: The 2015-USFQ Biennial Meeting on Growth Hormone Research.

Pediatr Endocrinol Rev 2015 Jun;12(4):396-407

Health and Science University, Portland, Oregon, and STAT5 LLC, Los Altos, CA, USA.

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June 2015
15 Reads

Relationship between the CYP2C9 IVS8-109A>T polymorphism and high losartan hydroxylation in healthy Ecuadorian volunteers.

Pharmacogenomics 2014 Aug;15(11):1417-21

CICAB Clinical Research Centre, Extremadura University Hospital & Medical School, Servicio Extremeño de Salud, Badajoz 06080, Spain.

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http://dx.doi.org/10.2217/pgs.14.85DOI Listing
August 2014
6 Reads
2 Citations
3.220 Impact Factor

Perception of the usefulness of drug/gene pairs and barriers for pharmacogenomics in Latin America.

Curr Drug Metab 2014 Feb;15(2):202-8

Laboratory of Chemical Carcinogenesis and Pharmacogenetics, IFT, Molecular and Clinical Pharmacology Program, ICBM, Faculty of Medicine, University of Chile; P.O. Box 70111. Carlos Schachtebeck 299, Quinta Normal, Santiago, Chile.

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February 2014
20 Reads
4 Citations
2.980 Impact Factor

Erythrocyte folate content and serum folic acid and homocysteine levels in preeclamptic primigravidae teenagers living at high altitude.

Arch Gynecol Obstet 2013 Nov 23;288(5):1011-5. Epub 2013 Apr 23.

Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador.

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http://dx.doi.org/10.1007/s00404-013-2851-7DOI Listing
November 2013
9 Reads
4 Citations
1.280 Impact Factor

Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes.

Drug Metabol Drug Interact 2012 ;27(4):217-33

CICAB Clinical Research Centre, Extremadura University Hospital and Medical School, Badajoz, Spain.

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http://dx.doi.org/10.1515/dmdi-2012-0018DOI Listing
June 2013
12 Reads
1 Citation

Losartan hydroxylation phenotype in an Ecuadorian population: influence of CYP2C9 genetic polymorphism, habits and gender.

Pharmacogenomics 2012 Nov;13(15):1711-7

CICAB Centro de Investigación Clínica, University of Extremadura, SES Servicio Extremeño de Salud, Hospital Universitario Infanta Cristina, 06080 Badajoz, Spain.

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http://dx.doi.org/10.2217/pgs.12.160DOI Listing
November 2012
5 Reads
3 Citations
3.220 Impact Factor

CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population.

Eur J Clin Pharmacol 2012 May 15;68(5):637-44. Epub 2011 Nov 15.

CICAB Clinical Research Centre, Extremadura University Hospital and Medical School, Badajoz, Spain.

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http://dx.doi.org/10.1007/s00228-011-1147-8DOI Listing
May 2012
13 Reads
3 Citations
2.970 Impact Factor

Effect of intravenous hydralazine infusion on maternal plasma nitric oxide levels in gestations complicated with severe preeclampsia: a pilot study.

Arch Gynecol Obstet 2012 Apr 19;285(4):1183-7. Epub 2012 Jan 19.

Biomedical Center, Universidad Central del Ecuador, Quito, Ecuador.

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http://dx.doi.org/10.1007/s00404-012-2217-6DOI Listing
April 2012
9 Reads
1.280 Impact Factor

Maternal plasma and amniotic fluid coenzyme Q10 levels in preterm and term gestations: a pilot study.

Arch Gynecol Obstet 2011 Mar 29;283 Suppl 1:67-71. Epub 2011 Mar 29.

Centro de Biomedicina, Universidad Central del Ecuador, Quito, Ecuador.

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http://dx.doi.org/10.1007/s00404-011-1894-xDOI Listing
March 2011
9 Reads
3 Citations
1.280 Impact Factor

Coenzyme Q10 supplementation during pregnancy reduces the risk of pre-eclampsia.

Int J Gynaecol Obstet 2009 Apr 19;105(1):43-5. Epub 2009 Jan 19.

Experimental Pharmacology and Cellular Metabolism Unit, Biomedical Center, Central University of Ecuador, Quito, Ecuador.

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http://dx.doi.org/10.1016/j.ijgo.2008.11.033DOI Listing
April 2009
23 Reads
10 Citations
1.563 Impact Factor

Coenzyme Q10 levels in women with preeclampsia living at different altitudes.

Biofactors 2008 ;32(1-4):185-90

Biomedical Center, Central University of Ecuador, Quito, Ecuador.

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February 2009
4 Reads
4.592 Impact Factor

Plasma and placental nitric oxide levels in women with and without pre-eclampsia living at different altitudes.

Int J Gynaecol Obstet 2009 Feb 22;104(2):140-2. Epub 2008 Nov 22.

Biomedical Center, Central University of Ecuador, Quito, Ecuador.

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http://dx.doi.org/10.1016/j.ijgo.2008.09.010DOI Listing
February 2009
6 Reads
3 Citations
1.563 Impact Factor

Molecular identification of endocervical Chlamydia trachomatis infection among gestations at risk for preterm birth in Ecuador.

Arch Gynecol Obstet 2009 Jan 15;279(1):9-10. Epub 2008 Apr 15.

Enrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, Ecuador.

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http://dx.doi.org/10.1007/s00404-008-0647-yDOI Listing
January 2009
5 Reads
3 Citations
1.280 Impact Factor

Prevalence of VP4 and VP7 genotypes of human rotavirus in Ecuadorian children with acute diarrhea.

J Med Virol 2008 Jun;80(6):1106-11

Hospital Metropolitano, Quito, Ecuador.

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http://dx.doi.org/10.1002/jmv.21181DOI Listing
June 2008
7 Reads
4 Citations
2.350 Impact Factor

Endothelial dysfunction and preeclampsia.

Am J Hypertens 2007 Sep;20(9):1026-7; author reply 1027

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http://dx.doi.org/10.1016/j.amjhyper.2007.01.022DOI Listing
September 2007
6 Reads
2.852 Impact Factor

Coenzyme Q10 is increased in placenta and cord blood during preeclampsia.

Biofactors 2005 ;25(1-4):153-8

Experimental Pharmacology and Cellular Metabolism Unit, Biomedical Center, Central University of Ecuador, Quito.

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October 2006
5 Reads
1 Citation
4.592 Impact Factor

NO in early pregnancy and development of preeclampsia.

Hypertension 2006 Apr 13;47(4):e17. Epub 2006 Feb 13.

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http://dx.doi.org/10.1161/01.HYP.0000205226.01641.feDOI Listing
April 2006
16 Reads
6.480 Impact Factor

Intraplatelet cyclic guanosine-3',5'-monophosphate levels during pregnancy and preeclampsia.

Hypertens Pregnancy 2004 ;23(3):303-8

Experimental Pharmacology and Cellular Metabolism Unit, Biomedical Center, Central University of Ecuador, Quito, Ecuador.

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http://dx.doi.org/10.1081/PRG-200030860DOI Listing
February 2005
3 Reads
1 Citation
1.192 Impact Factor

Oral ambroxol supplement in pregnant women induces fetal lung maturation.

Am J Obstet Gynecol 2004 Dec;191(6):2177; author reply 2178

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http://dx.doi.org/10.1016/j.ajog.2004.07.043DOI Listing
December 2004
5 Reads
1 Citation
4.704 Impact Factor

Preeclampsia is associated with a decrease in plasma coenzyme Q10 levels.

Free Radic Biol Med 2003 Dec;35(11):1453-6

Experimental Pharmacology and Cellular Metabolism Unit, Biomedical Center, Central University of Ecuador, Quito, Ecuador.

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December 2003
21 Reads
2 Citations
5.740 Impact Factor

Seroprevalence of antibodies to chlamydia pneumoniae in women with preeclampsia.

Obstet Gynecol 2003 Jul;102(1):198-9; author reply 199

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July 2003
8 Reads
3 Citations
5.175 Impact Factor

Physiological changes in platelet aggregation and nitric oxide levels during menstrual cycle in healthy women.

Nitric Oxide 2002 Nov;7(3):217-20

Experimental Pharmacology and Cellular Metabolism Unit, Biomedical Center, School of Medicine, Central University of Ecuador, Quito, Ecuador.

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November 2002
4 Reads
3.521 Impact Factor

Top co-authors

Enrique Teran
Enrique Teran

Universidad San Francisco de Quito

11
Sandra Vivero
Sandra Vivero

Central University of Ecuador

9
Carlos Escudero
Carlos Escudero

University of Oxford

7
Jaime Guevara-Aguirre
Jaime Guevara-Aguirre

Institute of Endocrinology

7
Adrian Llerena
Adrian Llerena

Extremadura University Hospital & Medical School

7
Peter Chedraui
Peter Chedraui

Institute of Biomedicine

6
Ricardo Izurieta
Ricardo Izurieta

University of South Florida

4
Ron Rosenfeld
Ron Rosenfeld

Oregon Health and Science University

4